{"id":"https://openalex.org/W1992907565","doi":"https://doi.org/10.1016/j.nmd.2009.06.014","title":"M.P.1.03 Preliminary results from single subcutaneous administration of ACE-031, a form of the soluble activin type IIB receptor, in healthy postmenopausal volunteers","display_name":"M.P.1.03 Preliminary results from single subcutaneous administration of ACE-031, a form of the soluble activin type IIB receptor, in healthy postmenopausal volunteers","publication_year":2009,"publication_date":"2009-07-31","ids":{"openalex":"https://openalex.org/W1992907565","doi":"https://doi.org/10.1016/j.nmd.2009.06.014","mag":"1992907565"},"language":"en","primary_location":{"id":"doi:10.1016/j.nmd.2009.06.014","doi":"https://doi.org/10.1016/j.nmd.2009.06.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.nmd.2009.06.014","pdf_url":null,"source":{"id":"https://openalex.org/S50004817","display_name":"Neuromuscular Disorders","issn_l":"0960-8966","issn":["0960-8966","1873-2364"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuromuscular Disorders","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108201050","display_name":"N.G. Borgstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112018","display_name":"Acceleron Pharma (United States)","ror":"https://ror.org/023annq56","country_code":"US","type":"company","lineage":["https://openalex.org/I4210112018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N.G. Borgstein","raw_affiliation_strings":["Acceleron Pharma, Cambridge, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acceleron Pharma, Cambridge, MA, United States","institution_ids":["https://openalex.org/I4210112018"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108244045","display_name":"C.H. Condon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112018","display_name":"Acceleron Pharma (United States)","ror":"https://ror.org/023annq56","country_code":"US","type":"company","lineage":["https://openalex.org/I4210112018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.H. Condon","raw_affiliation_strings":["Acceleron Pharma, Cambridge, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acceleron Pharma, Cambridge, MA, United States","institution_ids":["https://openalex.org/I4210112018"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028343495","display_name":"Yijun Yang","orcid":"https://orcid.org/0000-0002-6971-2503","observed_orcids":["https://orcid.org/0000-0002-6971-2503"]},"institutions":[{"id":"https://openalex.org/I4210112018","display_name":"Acceleron Pharma (United States)","ror":"https://ror.org/023annq56","country_code":"US","type":"company","lineage":["https://openalex.org/I4210112018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Y. Yang","raw_affiliation_strings":["Acceleron Pharma, Cambridge, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acceleron Pharma, Cambridge, MA, United States","institution_ids":["https://openalex.org/I4210112018"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110484488","display_name":"Dawn M. Wilson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112018","display_name":"Acceleron Pharma (United States)","ror":"https://ror.org/023annq56","country_code":"US","type":"company","lineage":["https://openalex.org/I4210112018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D.M. Wilson","raw_affiliation_strings":["Acceleron Pharma, Cambridge, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acceleron Pharma, Cambridge, MA, United States","institution_ids":["https://openalex.org/I4210112018"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006368558","display_name":"Eric Haltom","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112018","display_name":"Acceleron Pharma (United States)","ror":"https://ror.org/023annq56","country_code":"US","type":"company","lineage":["https://openalex.org/I4210112018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. Haltom","raw_affiliation_strings":["Acceleron Pharma, Cambridge, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acceleron Pharma, Cambridge, MA, United States","institution_ids":["https://openalex.org/I4210112018"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041514565","display_name":"Jennifer L. Lachey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112018","display_name":"Acceleron Pharma (United States)","ror":"https://ror.org/023annq56","country_code":"US","type":"company","lineage":["https://openalex.org/I4210112018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.L. Lachey","raw_affiliation_strings":["Acceleron Pharma, Cambridge, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acceleron Pharma, Cambridge, MA, United States","institution_ids":["https://openalex.org/I4210112018"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052288239","display_name":"Jasbir S. Seehra","orcid":"https://orcid.org/0009-0002-0843-8974","observed_orcids":["https://orcid.org/0009-0002-0843-8974"]},"institutions":[{"id":"https://openalex.org/I4210112018","display_name":"Acceleron Pharma (United States)","ror":"https://ror.org/023annq56","country_code":"US","type":"company","lineage":["https://openalex.org/I4210112018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Seehra","raw_affiliation_strings":["Acceleron Pharma, Cambridge, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acceleron Pharma, Cambridge, MA, United States","institution_ids":["https://openalex.org/I4210112018"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084012303","display_name":"Matthew Leigh Sherman","orcid":"https://orcid.org/0009-0009-4646-5819","observed_orcids":["https://orcid.org/0009-0009-4646-5819"]},"institutions":[{"id":"https://openalex.org/I4210112018","display_name":"Acceleron Pharma (United States)","ror":"https://ror.org/023annq56","country_code":"US","type":"company","lineage":["https://openalex.org/I4210112018"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.L. Sherman","raw_affiliation_strings":["Acceleron Pharma, Cambridge, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acceleron Pharma, Cambridge, MA, United States","institution_ids":["https://openalex.org/I4210112018"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210112018"],"apc_list":{"value":3470,"currency":"USD","value_usd":3470},"apc_paid":null,"fwci":0.2672,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.55203485,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"19","issue":"8-9","first_page":"546","last_page":"547"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12400","display_name":"Neurogenetic and Muscular Disorders Research","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/activin-receptor-type-iib","display_name":"ActRIIB","score":0.8740000128746033},{"id":"https://openalex.org/keywords/myostatin","display_name":"myostatin","score":0.9629999995231628},{"id":"https://openalex.org/keywords/fc-fusion-protein","display_name":"Fc fusion protein","score":0.9049999713897705},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.8339999914169312},{"id":"https://openalex.org/keywords/lean-body-mass","display_name":"lean body mass","score":0.7440000176429749},{"id":"https://openalex.org/keywords/adiposity","display_name":"adiposity","score":0.9160000085830688},{"id":"https://openalex.org/keywords/muscle-mass","display_name":"muscle mass","score":0.652999997138977},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.8489999771118164},{"id":"https://openalex.org/keywords/healthy-volunteers","display_name":"healthy volunteers","score":0.5199999809265137}],"concepts":[{"id":"https://openalex.org/C2778649528","wikidata":"https://www.wikidata.org/wiki/Q4677603","display_name":"Activin receptor","level":3,"score":0.7551132440567017},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6452469825744629},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6428210139274597},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6333400011062622},{"id":"https://openalex.org/C120863210","wikidata":"https://www.wikidata.org/wiki/Q17064264","display_name":"Lean body mass","level":3,"score":0.5872585773468018},{"id":"https://openalex.org/C3018603563","wikidata":"https://www.wikidata.org/wiki/Q177708","display_name":"Postmenopausal women","level":2,"score":0.5524135828018188},{"id":"https://openalex.org/C2777488582","wikidata":"https://www.wikidata.org/wiki/Q29630","display_name":"Myostatin","level":3,"score":0.5520777702331543},{"id":"https://openalex.org/C123894998","wikidata":"https://www.wikidata.org/wiki/Q425158","display_name":"Fusion protein","level":4,"score":0.4235613942146301},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38944268226623535},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35406002402305603},{"id":"https://openalex.org/C167414201","wikidata":"https://www.wikidata.org/wiki/Q1955391","display_name":"Muscle hypertrophy","level":2,"score":0.21847733855247498},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.20536822080612183},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12704592943191528},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.12683743238449097},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.nmd.2009.06.014","doi":"https://doi.org/10.1016/j.nmd.2009.06.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.nmd.2009.06.014","pdf_url":null,"source":{"id":"https://openalex.org/S50004817","display_name":"Neuromuscular Disorders","issn_l":"0960-8966","issn":["0960-8966","1873-2364"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuromuscular Disorders","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2095627243","https://openalex.org/W4206581875","https://openalex.org/W7128783823","https://openalex.org/W29379521","https://openalex.org/W2007231806","https://openalex.org/W2507377129","https://openalex.org/W1846967727","https://openalex.org/W2790085936","https://openalex.org/W1978783396","https://openalex.org/W2113036381"],"abstract_inverted_index":null,"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2016-06-24T00:00:00"}