{"id":"https://openalex.org/W1992249154","doi":"https://doi.org/10.1084/jem.171.5.1393","title":"LAG-3, a novel lymphocyte activation gene closely related to CD4.","display_name":"LAG-3, a novel lymphocyte activation gene closely related to CD4.","publication_year":1990,"publication_date":"1990-05-01","ids":{"openalex":"https://openalex.org/W1992249154","doi":"https://doi.org/10.1084/jem.171.5.1393","mag":"1992249154","pmid":"https://pubmed.ncbi.nlm.nih.gov/1692078","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2187904"},"language":"en","primary_location":{"id":"doi:10.1084/jem.171.5.1393","doi":"https://doi.org/10.1084/jem.171.5.1393","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.171.5.1393","pdf_url":"https://rupress.org/jem/article-pdf/171/5/1393/1670848/1393.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://rupress.org/jem/article-pdf/171/5/1393/1670848/1393.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013226213","display_name":"Fr\u00e9d\u00e9ric Triebel","orcid":"https://orcid.org/0000-0002-1526-7045","observed_orcids":["https://orcid.org/0000-0002-1526-7045"]},"institutions":[{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F Triebel","raw_affiliation_strings":["Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France","institution_ids":["https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010140625","display_name":"Setsuko Jitsukawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S Jitsukawa","raw_affiliation_strings":["Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France","institution_ids":["https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027017283","display_name":"Elena Baixer\u00e1s","orcid":"https://orcid.org/0000-0001-6955-2434","observed_orcids":["https://orcid.org/0000-0001-6955-2434"]},"institutions":[{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"E Baixeras","raw_affiliation_strings":["Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France","institution_ids":["https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075567455","display_name":"Sergio Roman\u2010Roman","orcid":"https://orcid.org/0000-0001-6459-2613","observed_orcids":["https://orcid.org/0000-0001-6459-2613"]},"institutions":[{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S Roman-Roman","raw_affiliation_strings":["Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France","institution_ids":["https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004764450","display_name":"Catherine Genev\u00e9e","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C Genevee","raw_affiliation_strings":["Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France","institution_ids":["https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111911183","display_name":"E. Vi\u00e9gas-P\u00e8quignot","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"E Viegas-Pequignot","raw_affiliation_strings":["Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France","institution_ids":["https://openalex.org/I2801843802"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015955183","display_name":"Thierry Hercend","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"T Hercend","raw_affiliation_strings":["Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Immunologie Cellulaire, Institut Gustave-Roussy, Villejuif, France","institution_ids":["https://openalex.org/I2801843802"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2801843802"],"apc_list":null,"apc_paid":null,"fwci":1.8327,"has_fulltext":true,"cited_by_count":940,"citation_normalized_percentile":{"value":0.85751007,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"171","issue":"5","first_page":"1393","last_page":"1405"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.011900000274181366,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lag-3","display_name":"LAG-3","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cd4","display_name":"CD4","score":0.7179999947547913},{"id":"https://openalex.org/keywords/immunoglobulin-superfamily","display_name":"immunoglobulin superfamily","score":0.8840000033378601},{"id":"https://openalex.org/keywords/t-cell-activation","display_name":"T cell activation","score":0.7310000061988831},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.9319999814033508},{"id":"https://openalex.org/keywords/gene-duplication","display_name":"gene duplication","score":0.8009999990463257},{"id":"https://openalex.org/keywords/chromosome-12","display_name":"chromosome 12","score":0.7609999775886536},{"id":"https://openalex.org/keywords/gene-structure","display_name":"gene structure","score":0.39100000262260437},{"id":"https://openalex.org/keywords/membrane-proteins","display_name":"membrane proteins","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.7157939076423645},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6994487047195435},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6919687390327454},{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.6299493312835693},{"id":"https://openalex.org/C7602840","wikidata":"https://www.wikidata.org/wiki/Q746284","display_name":"Gene duplication","level":3,"score":0.6201452612876892},{"id":"https://openalex.org/C187882448","wikidata":"https://www.wikidata.org/wiki/Q283478","display_name":"Complementary DNA","level":3,"score":0.5592124462127686},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5536254644393921},{"id":"https://openalex.org/C91682701","wikidata":"https://www.wikidata.org/wiki/Q41797304","display_name":"Immunoglobulin superfamily","level":3,"score":0.5129682421684265},{"id":"https://openalex.org/C149774189","wikidata":"https://www.wikidata.org/wiki/Q24770541","display_name":"Immunoglobulin domain","level":3,"score":0.510761022567749}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D012689","descriptor_name":"Sequence Homology, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015139","descriptor_name":"Blotting, Southern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015152","descriptor_name":"Blotting, Northern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015183","descriptor_name":"Restriction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015703","descriptor_name":"Antigens, CD","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015704","descriptor_name":"CD4 Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015723","descriptor_name":"Gene Library","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1084/jem.171.5.1393","doi":"https://doi.org/10.1084/jem.171.5.1393","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.171.5.1393","pdf_url":"https://rupress.org/jem/article-pdf/171/5/1393/1670848/1393.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"journal-article"},{"id":"pmid:1692078","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1692078","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:2187904","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2187904/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Med","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.285.1765","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.285.1765","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/39/ac/J_Exp_Med_1990_May_1_171(5)_1393-1405.tar.gz","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.329.6774","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.329.6774","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jem.rupress.org/content/171/5/1393.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1084/jem.171.5.1393","doi":"https://doi.org/10.1084/jem.171.5.1393","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.171.5.1393","pdf_url":"https://rupress.org/jem/article-pdf/171/5/1393/1670848/1393.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1992249154.pdf","grobid_xml":"https://content.openalex.org/works/W1992249154.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W1518942907","https://openalex.org/W1554864410","https://openalex.org/W1590194625","https://openalex.org/W1923598425","https://openalex.org/W1927207766","https://openalex.org/W1963769713","https://openalex.org/W1975276582","https://openalex.org/W1976887761","https://openalex.org/W1980894283","https://openalex.org/W1983224547","https://openalex.org/W1984266461","https://openalex.org/W1995948010","https://openalex.org/W2009105413","https://openalex.org/W2010320204","https://openalex.org/W2013368806","https://openalex.org/W2014669590","https://openalex.org/W2031209863","https://openalex.org/W2033472484","https://openalex.org/W2034620614","https://openalex.org/W2041154872","https://openalex.org/W2047242645","https://openalex.org/W2065692062","https://openalex.org/W2066160869","https://openalex.org/W2068802770","https://openalex.org/W2073516346","https://openalex.org/W2083556128","https://openalex.org/W2091239909","https://openalex.org/W2104307198","https://openalex.org/W2129270483","https://openalex.org/W2137129539","https://openalex.org/W2138270253","https://openalex.org/W2419387879"],"related_works":["https://openalex.org/W3028834592","https://openalex.org/W4250744419","https://openalex.org/W564866365","https://openalex.org/W3166972371","https://openalex.org/W3175920168","https://openalex.org/W2038325956","https://openalex.org/W2018710900","https://openalex.org/W2068487611","https://openalex.org/W1480698358","https://openalex.org/W3032474257"],"abstract_inverted_index":{"We":[0],"have":[1],"identified":[2],"a":[3,45,124,128],"novel":[4],"human":[5],"gene":[6,16,37,126],"of":[7,14,74,123,135,176,180],"the":[8,41,60,72,75,89,97,154,165,173,177],"Ig":[9],"superfamily,":[10],"designated":[11],"LAG-3.":[12],"Expression":[13],"this":[15],"is":[17,24,63,114,162],"undetectable":[18],"in":[19,29,71,96],"resting":[20],"PBL,":[21],"while":[22],"it":[23,62,66],"found":[25,95],"(a":[26],"2-kb":[27],"message)":[28],"activated":[30],"T":[31],"and":[32,77,103,111,137],"NK":[33],"cells.":[34],"The":[35,55,83,132],"LAG-3":[36,98,118,136],"includes":[38,67],"eight":[39],"exons;":[40],"corresponding":[42],"cDNA":[43],"encodes":[44],"498-amino":[46],"acid":[47],"membrane":[48],"protein":[49],"with":[50,139],"four":[51],"extracellular":[52],"IgSF":[53],"domains.":[54],"first":[56],"one":[57],"belongs":[58],"to":[59,88,141],"V-SET;":[61],"particular":[64],"since":[65],"an":[68,78],"extra":[69],"loop":[70],"middle":[73],"domain":[76],"unusual":[79],"intrachain":[80],"disulphide":[81],"bridge.":[82],"three":[84],"other":[85],"domains":[86,101,109],"belong":[87],"C2-SET.":[90],"Strong":[91],"internal":[92],"homologies":[93],"are":[94,157,170],"molecule":[99],"between":[100,108],"1":[102],"3,":[104],"as":[105,107,146,148],"well":[106,147],"2":[110],"4.":[112],"It":[113],"therefore":[115],"likely":[116],"that":[117,153,167],"has":[119],"evolved":[120],"by":[121,164],"duplication":[122],"pre-existing":[125],"encoding":[127],"two":[129,155],"IgSF-domain":[130],"structure.":[131],"compared":[133],"analysis":[134],"CD4,":[138],"respect":[140],"both":[142,168],"their":[143,149],"peptidic":[144],"sequence":[145],"exon/intron":[150],"organization,":[151],"indicated":[152],"molecules":[156],"closely":[158],"related.":[159],"This":[160],"point":[161],"strengthened":[163],"finding":[166],"genes":[169],"located":[171],"on":[172],"distal":[174],"part":[175],"short":[178],"arm":[179],"chromosome":[181],"12.":[182]},"counts_by_year":[{"year":2026,"cited_by_count":44},{"year":2025,"cited_by_count":82},{"year":2024,"cited_by_count":110},{"year":2023,"cited_by_count":100},{"year":2022,"cited_by_count":88},{"year":2021,"cited_by_count":84},{"year":2020,"cited_by_count":79},{"year":2019,"cited_by_count":61},{"year":2018,"cited_by_count":52},{"year":2017,"cited_by_count":38},{"year":2016,"cited_by_count":25},{"year":2015,"cited_by_count":25},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}