{"id":"https://openalex.org/W1992054580","doi":"https://doi.org/10.1016/s0016-5085(09)60217-1","title":"246 Is the Murine Dextran Sodium Sulfate-Induced Colitis Model Valid for Predicting Drug Efficacy in IBD?","display_name":"246 Is the Murine Dextran Sodium Sulfate-Induced Colitis Model Valid for Predicting Drug Efficacy in IBD?","publication_year":2009,"publication_date":"2009-05-01","ids":{"openalex":"https://openalex.org/W1992054580","doi":"https://doi.org/10.1016/s0016-5085(09)60217-1","mag":"1992054580"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(09)60217-1","doi":"https://doi.org/10.1016/s0016-5085(09)60217-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(09)60217-1","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039343038","display_name":"Yvette M. Petersen","orcid":"https://orcid.org/0000-0002-1643-2137","observed_orcids":["https://orcid.org/0000-0002-1643-2137"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yvette M. Petersen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058707979","display_name":"Birgitte Bj\u00f6rkenberg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Birgitte Bj\u00f4rkenberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079052701","display_name":"Kennet N. Christjansen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kennet N. Christjansen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043924024","display_name":"Martin Stalhut","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martin Stalhut","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081266608","display_name":"Henrik Duelund Pedersen","orcid":"https://orcid.org/0000-0003-0687-5134","observed_orcids":["https://orcid.org/0000-0003-0687-5134"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Henrik D. Pedersen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5000047912","display_name":"Christian Thorkildsen","orcid":"https://orcid.org/0000-0001-9450-6675","observed_orcids":["https://orcid.org/0000-0001-9450-6675"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christian Thorkildsen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4180,"currency":"USD","value_usd":4180},"apc_paid":null,"fwci":0.3207,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.6623246,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"136","issue":"5","first_page":"A","last_page":"48"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dss-induced-colitis","display_name":"DSS-induced colitis","score":0.8769999742507935},{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.890999972820282},{"id":"https://openalex.org/keywords/murine-colitis-model","display_name":"murine colitis model","score":0.7599999904632568},{"id":"https://openalex.org/keywords/drug-efficacy-prediction","display_name":"drug efficacy prediction","score":0.8289999961853027},{"id":"https://openalex.org/keywords/il-21","display_name":"IL-21","score":0.8379999995231628},{"id":"https://openalex.org/keywords/il-12-23p40","display_name":"IL-12/23p40","score":0.9079999923706055},{"id":"https://openalex.org/keywords/colitis-severity","display_name":"colitis severity","score":0.5600000023841858}],"concepts":[{"id":"https://openalex.org/C2775862500","wikidata":"https://www.wikidata.org/wiki/Q2453464","display_name":"Colitis","level":2,"score":0.7657428979873657},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.61615389585495},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.6145806312561035},{"id":"https://openalex.org/C2777339698","wikidata":"https://www.wikidata.org/wiki/Q423123","display_name":"Dextran","level":2,"score":0.5399406552314758},{"id":"https://openalex.org/C2778343803","wikidata":"https://www.wikidata.org/wiki/Q172290","display_name":"Sulfate","level":2,"score":0.4368249773979187},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4347797632217407},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.4142894148826599},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38739675283432007},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.2093939185142517},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.17972460389137268},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0016-5085(09)60217-1","doi":"https://doi.org/10.1016/s0016-5085(09)60217-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(09)60217-1","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2108105869","https://openalex.org/W2084148498","https://openalex.org/W2978639670","https://openalex.org/W2011556145","https://openalex.org/W1964716453","https://openalex.org/W2001138503","https://openalex.org/W2058783730","https://openalex.org/W3194338751","https://openalex.org/W7125400249","https://openalex.org/W2003162335"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}