{"id":"https://openalex.org/W1992014434","doi":"https://doi.org/10.1111/j.1365-2133.2005.06830.x","title":"Investigation of the use of the pulsed dye laser in the treatment of Bowen's disease using 5-aminolaevulinic acid phototherapy","display_name":"Investigation of the use of the pulsed dye laser in the treatment of Bowen's disease using 5-aminolaevulinic acid phototherapy","publication_year":2005,"publication_date":"2005-09-16","ids":{"openalex":"https://openalex.org/W1992014434","doi":"https://doi.org/10.1111/j.1365-2133.2005.06830.x","mag":"1992014434","pmid":"https://pubmed.ncbi.nlm.nih.gov/16181460"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-2133.2005.06830.x","doi":"https://doi.org/10.1111/j.1365-2133.2005.06830.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-2133.2005.06830.x","pdf_url":null,"source":{"id":"https://openalex.org/S45720283","display_name":"British Journal of Dermatology","issn_l":"0007-0963","issn":["0007-0963","1365-2133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Dermatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040717428","display_name":"Jason Britton","orcid":"https://orcid.org/0000-0002-3145-9274","observed_orcids":["https://orcid.org/0000-0002-3145-9274"]},"institutions":[{"id":"https://openalex.org/I1295121038","display_name":"Leeds General Infirmary","ror":"https://ror.org/04hrjej96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1295121038","https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"J.E.R. Britton","raw_affiliation_strings":["Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K. info@dermatology.co.uk","Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K.\u2028"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K. info@dermatology.co.uk","institution_ids":["https://openalex.org/I1295121038"]},{"raw_affiliation_string":"Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K.\u2028","institution_ids":["https://openalex.org/I1295121038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075663951","display_name":"Victoria Goulden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295121038","display_name":"Leeds General Infirmary","ror":"https://ror.org/04hrjej96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1295121038","https://openalex.org/I2799390153"]},{"id":"https://openalex.org/I130828816","display_name":"University of Leeds","ror":"https://ror.org/024mrxd33","country_code":"GB","type":"education","lineage":["https://openalex.org/I130828816"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"V. Goulden","raw_affiliation_strings":["Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K. *Centre for Photobiology and Photodynamic Therapy, Department of Medical Physics, University of Leeds, Leeds, West Yorkshire, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K. *Centre for Photobiology and Photodynamic Therapy, Department of Medical Physics, University of Leeds, Leeds, West Yorkshire, U.K","institution_ids":["https://openalex.org/I1295121038","https://openalex.org/I130828816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113579541","display_name":"Graeme I Stables","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295121038","display_name":"Leeds General Infirmary","ror":"https://ror.org/04hrjej96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1295121038","https://openalex.org/I2799390153"]},{"id":"https://openalex.org/I130828816","display_name":"University of Leeds","ror":"https://ror.org/024mrxd33","country_code":"GB","type":"education","lineage":["https://openalex.org/I130828816"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"G. Stables","raw_affiliation_strings":["Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K. *Centre for Photobiology and Photodynamic Therapy, Department of Medical Physics, University of Leeds, Leeds, West Yorkshire, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K. *Centre for Photobiology and Photodynamic Therapy, Department of Medical Physics, University of Leeds, Leeds, West Yorkshire, U.K","institution_ids":["https://openalex.org/I1295121038","https://openalex.org/I130828816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105771233","display_name":"Mark R. Stringer","orcid":"https://orcid.org/0000-0003-2102-1049","observed_orcids":["https://orcid.org/0000-0003-2102-1049"]},"institutions":[{"id":"https://openalex.org/I1295121038","display_name":"Leeds General Infirmary","ror":"https://ror.org/04hrjej96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1295121038","https://openalex.org/I2799390153"]},{"id":"https://openalex.org/I130828816","display_name":"University of Leeds","ror":"https://ror.org/024mrxd33","country_code":"GB","type":"education","lineage":["https://openalex.org/I130828816"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. Stringer","raw_affiliation_strings":["Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K. *Centre for Photobiology and Photodynamic Therapy, Department of Medical Physics, University of Leeds, Leeds, West Yorkshire, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K. *Centre for Photobiology and Photodynamic Therapy, Department of Medical Physics, University of Leeds, Leeds, West Yorkshire, U.K","institution_ids":["https://openalex.org/I1295121038","https://openalex.org/I130828816"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111993666","display_name":"Robert Alexander Sheehan-Dare","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295121038","display_name":"Leeds General Infirmary","ror":"https://ror.org/04hrjej96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1295121038","https://openalex.org/I2799390153"]},{"id":"https://openalex.org/I130828816","display_name":"University of Leeds","ror":"https://ror.org/024mrxd33","country_code":"GB","type":"education","lineage":["https://openalex.org/I130828816"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R. Sheehan-Dare","raw_affiliation_strings":["Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K. *Centre for Photobiology and Photodynamic Therapy, Department of Medical Physics, University of Leeds, Leeds, West Yorkshire, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leeds Centre for Dermatology, Leeds General Infirmary, Leeds, West Yorkshire, U.K. *Centre for Photobiology and Photodynamic Therapy, Department of Medical Physics, University of Leeds, Leeds, West Yorkshire, U.K","institution_ids":["https://openalex.org/I1295121038","https://openalex.org/I130828816"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5040717428"],"corresponding_institution_ids":["https://openalex.org/I1295121038"],"apc_list":{"value":3731,"currency":"GBP","value_usd":4920},"apc_paid":null,"fwci":5.1515,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.94676834,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"153","issue":"4","first_page":"780","last_page":"784"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.5669000148773193,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.5669000148773193,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.4255000054836273,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bowen-s-disease","display_name":"Bowen's disease","score":0.9890000224113464},{"id":"https://openalex.org/keywords/pulsed-dye-laser","display_name":"pulsed dye laser","score":0.8320000171661377},{"id":"https://openalex.org/keywords/5-aminolevulinic-acid","display_name":"5-aminolevulinic acid","score":0.9150000214576721},{"id":"https://openalex.org/keywords/photodynamic-therapy","display_name":"photodynamic therapy","score":0.9800000190734863},{"id":"https://openalex.org/keywords/protoporphyrin-ix","display_name":"protoporphyrin IX","score":0.8809999823570251},{"id":"https://openalex.org/keywords/585-nm-laser","display_name":"585 nm laser","score":0.7300000190734863},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.46700000762939453},{"id":"https://openalex.org/keywords/recurrence","display_name":"recurrence","score":0.5879999995231628},{"id":"https://openalex.org/keywords/treatment-safety","display_name":"treatment safety","score":0.5860000252723694},{"id":"https://openalex.org/keywords/skin-cancer-prevention","display_name":"skin cancer prevention","score":0.4580000042915344},{"id":"https://openalex.org/keywords/hand-lesions","display_name":"hand lesions","score":0.5699999928474426},{"id":"https://openalex.org/keywords/foot-lesions","display_name":"foot lesions","score":0.9419999718666077},{"id":"https://openalex.org/keywords/treatment-duration-reduction","display_name":"treatment time reduction","score":0.41499999165534973}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7645252346992493},{"id":"https://openalex.org/C2781280921","wikidata":"https://www.wikidata.org/wiki/Q5749018","display_name":"Bowen's disease","level":3,"score":0.6402658224105835},{"id":"https://openalex.org/C2781323092","wikidata":"https://www.wikidata.org/wiki/Q1428072","display_name":"Photodynamic therapy","level":2,"score":0.5337297320365906},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.448282390832901},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.41591739654541016},{"id":"https://openalex.org/C2776714205","wikidata":"https://www.wikidata.org/wiki/Q1193171","display_name":"Intense pulsed light","level":2,"score":0.4151875972747803},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.38833415508270264},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.34897851943969727},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.16233929991722107},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.10238757729530334},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000622","descriptor_name":"Aminolevulinic Acid","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001913","descriptor_name":"Bowen's Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001913","descriptor_name":"Bowen's Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007834","descriptor_name":"Lasers","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010778","descriptor_name":"Photochemotherapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D010778","descriptor_name":"Photochemotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017319","descriptor_name":"Photosensitizing Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D053685","descriptor_name":"Laser Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1365-2133.2005.06830.x","doi":"https://doi.org/10.1111/j.1365-2133.2005.06830.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-2133.2005.06830.x","pdf_url":null,"source":{"id":"https://openalex.org/S45720283","display_name":"British Journal of Dermatology","issn_l":"0007-0963","issn":["0007-0963","1365-2133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Dermatology","raw_type":"journal-article"},{"id":"pmid:16181460","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16181460","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The British journal of dermatology","raw_type":"Evaluation Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W136746920","https://openalex.org/W1506108633","https://openalex.org/W1566380245","https://openalex.org/W1965943262","https://openalex.org/W1974985063","https://openalex.org/W1981396245","https://openalex.org/W1987479252","https://openalex.org/W1999051172","https://openalex.org/W2005514258","https://openalex.org/W2025084317","https://openalex.org/W2037429015","https://openalex.org/W2037448493","https://openalex.org/W2038063038","https://openalex.org/W2039346519","https://openalex.org/W2040858046","https://openalex.org/W2080795148","https://openalex.org/W2098717091","https://openalex.org/W2114301387","https://openalex.org/W4253817109"],"related_works":["https://openalex.org/W2378839552","https://openalex.org/W1547465700","https://openalex.org/W2348417685","https://openalex.org/W1496598979","https://openalex.org/W2347940076","https://openalex.org/W2964903048","https://openalex.org/W7124548459","https://openalex.org/W2094399906","https://openalex.org/W1982224418","https://openalex.org/W2022124544"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,46,111,144,208,382],"use":[2,41,255],"of":[3,12,28,42,48,58,70,86,89,129,140,159,162,184,197,211,214,226,247,256,276,304,360],"5-aminolaevulinic":[4],"acid":[5],"photodynamic":[6],"therapy":[7,321],"(ALA-PDT)":[8],"for":[9,68,108,181,358,379],"the":[10,26,40,54,59,65,71,151,156,160,212,254,285,351,388,396],"treatment":[11,19,30,189,250,263,371,399],"Bowen's":[13,76,92,163,215,361],"disease":[14,77,93,164,216],"is":[15,353],"well":[16,385],"established.":[17],"However,":[18,387],"with":[20,83,96,132,313,395],"a":[21,84,117,127,133,138,182,224,298,308,323],"continuous":[22],"light":[23,66,356],"source":[24,67,357,364],"has":[25,348],"disadvantage":[27],"prolonged":[29,336],"time":[31,372],"during":[32,249],"which":[33],"patients":[34,82,243,312],"often":[35],"experience":[36],"significant":[37],"discomfort":[38,248,337],"requiring":[39,223],"local":[43,257],"anaesthetic.":[44,258],"OBJECTIVES:":[45],"aim":[47],"this":[49],"study":[50,347],"was":[51,217,384,391],"to":[52,74,149,187,270,405],"assess":[53,188],"efficacy":[55,414],"and":[56,153,191,200,205,238,274,335],"safety":[57],"pulsed":[60],"dye":[61],"laser":[62],"(PDL)":[63],"as":[64],"photoactivation":[69],"protoporphyrin":[72],"IX":[73],"treat":[75],"by":[78,147,165],"PDT.":[79],"METHODS:":[80],"Thirteen":[81],"total":[85],"17":[87,286],"patches":[88,112,213,295,334],"histologically":[90],"proven":[91],"were":[94,113,169,233],"treated":[95],"20%":[97],"5-ALA":[98],"in":[99,281,332,342],"Unguentum":[100],"M":[101],"(Crookes":[102],"Healthcare,":[103],"Nottingham,":[104],"U.K.)":[105],"under":[106],"occlusion":[107],"4":[109],"h.":[110],"then":[114,170,177],"irradiated":[115],"using":[116,126],"Candela":[118],"SPLTL-1b":[119],"(Candela":[120],"Corporation,":[121],"Wayland,":[122],"MA,":[123],"U.S.A.)":[124],"PDL":[125,352],"wavelength":[128],"585":[130],"nm,":[131],"7-mm":[134],"diameter":[135],"spot":[136],"at":[137,174,178,291],"fluence":[139],"10":[141,198],"J":[142],"cm(-2).":[143],"spots":[145],"overlapped":[146],"50%":[148],"cover":[150],"lesion":[152],"extend":[154],"beyond":[155],"clinical":[157,300],"margin":[158],"patch":[161],"0.5":[166],"cm.":[167],"Patients":[168],"followed":[171],"up":[172],"initially":[173],"2":[175,260],"months,":[176],"3-monthly":[179],"intervals":[180],"period":[183],"12":[185],"months":[186,261],"success":[190],"recurrence":[192],"rate.":[193],"RESULTS:":[194],"Subjects":[195],"consisted":[196],"females":[199],"three":[201,314],"males,":[202],"between":[203],"47":[204],"88":[206],"years.":[207],"mean":[209],"area":[210],"315.4":[218],"mm(2)":[219],"(range":[220,229],"36-2464":[221],"mm(2))":[222],"median":[225],"32":[227],"pulses":[228],"3-260).":[230],"Lesions":[231],"sites":[232,264],"hands":[234],"(two),":[235],"foot":[236],"(one)":[237],"lower":[239,408],"leg":[240],"(14).":[241],"All":[242],"experienced":[244],"varying":[245],"degrees":[246],"but":[251],"none":[252],"required":[253,307,319],"At":[259],"eight":[262,333],"could":[265],"not":[266,374],"be":[267,376],"assessed":[268],"due":[269],"loose":[271],"overlying":[272],"crusts":[273],"removal":[275],"these":[277,305],"revealed":[278],"superficial":[279],"erosions":[280],"seven":[282],"patients.":[283,344],"Of":[284],"lesions":[287,315],"treated,":[288],"on":[289],"follow-up":[290],"1":[292],"year,":[293],"14":[294],"(82%)":[296],"demonstrated":[297],"complete":[299],"response,":[301],"although":[302,369],"one":[303],"had":[306],"second":[309,324],"treatment.":[310,325],"Two":[311],"that":[316,350],"would":[317],"have":[318],"further":[320],"refused":[322],"Prolonged":[326],"crusting":[327],"lasting":[328,338],"8":[329],"weeks":[330,340],"occurred":[331,341],"6":[339],"four":[343],"CONCLUSIONS:":[345],"This":[346],"shown":[349],"an":[354],"effective":[355],"ALA-PDT":[359],"disease.":[362],"Light":[363],"exposure":[365],"times":[366],"are":[367,403],"shorter,":[368],"overall":[370],"may":[373],"always":[375],"significantly":[377],"reduced":[378],"larger":[380],"lesions.":[381],"procedure":[383],"tolerated.":[386],"post-treatment":[389,417],"morbidity":[390],"relatively":[392],"high":[393],"compared":[394],"more":[397],"conventional":[398],"modalities.":[400],"Further":[401],"studies":[402],"needed":[404],"determine":[406],"whether":[407],"energy":[409],"fluences":[410],"can":[411],"maintain":[412],"similar":[413],"while":[415],"reducing":[416],"morbidity.":[418]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}