{"id":"https://openalex.org/W1992010411","doi":"https://doi.org/10.1016/j.cytogfr.2014.06.004","title":"IFI16: At the interphase between innate DNA sensing and genome regulation","display_name":"IFI16: At the interphase between innate DNA sensing and genome regulation","publication_year":2014,"publication_date":"2014-06-21","ids":{"openalex":"https://openalex.org/W1992010411","doi":"https://doi.org/10.1016/j.cytogfr.2014.06.004","mag":"1992010411","pmid":"https://pubmed.ncbi.nlm.nih.gov/25027602"},"language":"en","primary_location":{"id":"doi:10.1016/j.cytogfr.2014.06.004","doi":"https://doi.org/10.1016/j.cytogfr.2014.06.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cytogfr.2014.06.004","pdf_url":null,"source":{"id":"https://openalex.org/S194552188","display_name":"Cytokine & Growth Factor Reviews","issn_l":"1359-6101","issn":["1359-6101","1879-0305"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytokine & Growth Factor Reviews","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064287991","display_name":"Martin R. Jakobsen","orcid":"https://orcid.org/0000-0001-8847-9201","observed_orcids":["https://orcid.org/0000-0001-8847-9201"]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Martin R. Jakobsen","raw_affiliation_strings":["Department of Biomedicine, Aarhus University, Aarhus, Denmark; Aarhus Research Center for Innate Immunology, Aarhus University, Aarhus, Denmark","Department of Biomedicine Aarhus University Aarhus Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, Aarhus University, Aarhus, Denmark; Aarhus Research Center for Innate Immunology, Aarhus University, Aarhus, Denmark","institution_ids":["https://openalex.org/I204337017"]},{"raw_affiliation_string":"Department of Biomedicine Aarhus University Aarhus Denmark","institution_ids":["https://openalex.org/I204337017"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082089381","display_name":"S\u00f8ren R. Paludan","orcid":"https://orcid.org/0000-0001-9180-4060","observed_orcids":["https://orcid.org/0000-0001-9180-4060"]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"S\u00f8ren R. Paludan","raw_affiliation_strings":["Department of Biomedicine, Aarhus University, Aarhus, Denmark; Aarhus Research Center for Innate Immunology, Aarhus University, Aarhus, Denmark. Electronic address: srp@biomed.au.dk","Department of Biomedicine Aarhus University Aarhus Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, Aarhus University, Aarhus, Denmark; Aarhus Research Center for Innate Immunology, Aarhus University, Aarhus, Denmark. Electronic address: srp@biomed.au.dk","institution_ids":["https://openalex.org/I204337017"]},{"raw_affiliation_string":"Department of Biomedicine Aarhus University Aarhus Denmark","institution_ids":["https://openalex.org/I204337017"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204337017"],"apc_list":{"value":4900,"currency":"USD","value_usd":4900},"apc_paid":null,"fwci":0.7438,"has_fulltext":false,"cited_by_count":73,"citation_normalized_percentile":{"value":0.60548885,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"25","issue":"6","first_page":"649","last_page":"655"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ifi16","display_name":"IFI16","score":1.0},{"id":"https://openalex.org/keywords/pyrin-domain","display_name":"pyrin domain","score":0.8809999823570251},{"id":"https://openalex.org/keywords/dna-sensing","display_name":"DNA sensing","score":0.7609999775886536},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.8600000143051147},{"id":"https://openalex.org/keywords/pattern-recognition-receptors","display_name":"pattern recognition receptors","score":0.9210000038146973},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.9380000233650208},{"id":"https://openalex.org/keywords/genome-regulation","display_name":"genome regulation","score":0.718999981880188},{"id":"https://openalex.org/keywords/cytosolic-dna","display_name":"cytosolic DNA","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C139174496","wikidata":"https://www.wikidata.org/wiki/Q24725912","display_name":"Pyrin domain","level":4,"score":0.8716636896133423},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.750985324382782},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6144524812698364},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5503312349319458},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4859529733657837},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4692437946796417},{"id":"https://openalex.org/C111289621","wikidata":"https://www.wikidata.org/wiki/Q418772","display_name":"Pattern recognition receptor","level":4,"score":0.45765459537506104},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4440488815307617},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4411270022392273},{"id":"https://openalex.org/C2777209026","wikidata":"https://www.wikidata.org/wiki/Q412405","display_name":"Inflammasome","level":3,"score":0.3967609405517578},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.32355478405952454},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2281983494758606}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D003600","descriptor_name":"Cytosol","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009687","descriptor_name":"Nuclear Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009687","descriptor_name":"Nuclear Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.cytogfr.2014.06.004","doi":"https://doi.org/10.1016/j.cytogfr.2014.06.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cytogfr.2014.06.004","pdf_url":null,"source":{"id":"https://openalex.org/S194552188","display_name":"Cytokine & Growth Factor Reviews","issn_l":"1359-6101","issn":["1359-6101","1879-0305"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytokine & Growth Factor Reviews","raw_type":"journal-article"},{"id":"pmid:25027602","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25027602","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytokine & growth factor reviews","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:publications/6d15e69b-d1ac-4449-86fa-b029dd629a2d","doi":null,"is_oa":false,"landing_page_url":"https://pure.au.dk/portal/en/publications/6d15e69b-d1ac-4449-86fa-b029dd629a2d","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Jakobsen, M R & Paludan, S R 2014, 'IFI16 : At the interphase between innate DNA sensing and genome regulation', Cytokine & Growth Factor Reviews. https://doi.org/10.1016/j.cytogfr.2014.06.004","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1263886752","display_name":null,"funder_award_id":"12-124330","funder_id":"https://openalex.org/F4320310483","funder_display_name":"Sundhed og Sygdom, Det Frie Forskningsr\u00e5d"},{"id":"https://openalex.org/G6362567440","display_name":null,"funder_award_id":"R83-2011-7598","funder_id":"https://openalex.org/F4320321999","funder_display_name":"Lundbeckfonden"},{"id":"https://openalex.org/G7327882799","display_name":null,"funder_award_id":"10-081986","funder_id":"https://openalex.org/F4320310483","funder_display_name":"Sundhed og Sygdom, Det Frie Forskningsr\u00e5d"},{"id":"https://openalex.org/G8530078436","display_name":null,"funder_award_id":"R34-3855","funder_id":"https://openalex.org/F4320321999","funder_display_name":"Lundbeckfonden"}],"funders":[{"id":"https://openalex.org/F4320310483","display_name":"Sundhed og Sygdom, Det Frie Forskningsr\u00e5d","ror":"https://ror.org/03ge1nb22"},{"id":"https://openalex.org/F4320321999","display_name":"Lundbeckfonden","ror":"https://ror.org/03hz8wd80"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W1559117436","https://openalex.org/W1587068679","https://openalex.org/W1927742265","https://openalex.org/W1934619019","https://openalex.org/W1964253344","https://openalex.org/W1969249937","https://openalex.org/W1969404855","https://openalex.org/W1969888906","https://openalex.org/W1986164739","https://openalex.org/W1987448837","https://openalex.org/W1990469316","https://openalex.org/W1997069349","https://openalex.org/W2002525330","https://openalex.org/W2012318771","https://openalex.org/W2012580035","https://openalex.org/W2016131266","https://openalex.org/W2027130956","https://openalex.org/W2032898598","https://openalex.org/W2033448230","https://openalex.org/W2034291831","https://openalex.org/W2038433774","https://openalex.org/W2041153925","https://openalex.org/W2042433863","https://openalex.org/W2042816890","https://openalex.org/W2043215173","https://openalex.org/W2048545688","https://openalex.org/W2053543776","https://openalex.org/W2056220051","https://openalex.org/W2056615762","https://openalex.org/W2058277625","https://openalex.org/W2060552527","https://openalex.org/W2060822159","https://openalex.org/W2073207414","https://openalex.org/W2074012862","https://openalex.org/W2075225148","https://openalex.org/W2079716935","https://openalex.org/W2083093678","https://openalex.org/W2091174536","https://openalex.org/W2091386277","https://openalex.org/W2093578280","https://openalex.org/W2099610218","https://openalex.org/W2104912263","https://openalex.org/W2105121872","https://openalex.org/W2109735258","https://openalex.org/W2110104528","https://openalex.org/W2116803339","https://openalex.org/W2119864130","https://openalex.org/W2130142523","https://openalex.org/W2131617804","https://openalex.org/W2132093817","https://openalex.org/W2141515661","https://openalex.org/W2142433291","https://openalex.org/W2148824237","https://openalex.org/W2150058561","https://openalex.org/W2154171253","https://openalex.org/W2158542519","https://openalex.org/W2161327441","https://openalex.org/W2162717091","https://openalex.org/W2163362670","https://openalex.org/W2163671315","https://openalex.org/W2163804619","https://openalex.org/W2314334585"],"related_works":["https://openalex.org/W2091500277","https://openalex.org/W2094249034","https://openalex.org/W2795581574","https://openalex.org/W2131617804","https://openalex.org/W7124268751","https://openalex.org/W2094007886","https://openalex.org/W2075126232","https://openalex.org/W7135930036","https://openalex.org/W4313356755","https://openalex.org/W4313355029"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}