{"id":"https://openalex.org/W1992004735","doi":"https://doi.org/10.1021/bi00117a008","title":"HMG proteins 14 and 17 become cross-linked to the globular domain of histone H3 near the nucleosome core particle dyad","display_name":"HMG proteins 14 and 17 become cross-linked to the globular domain of histone H3 near the nucleosome core particle dyad","publication_year":1992,"publication_date":"1992-01-21","ids":{"openalex":"https://openalex.org/W1992004735","doi":"https://doi.org/10.1021/bi00117a008","mag":"1992004735","pmid":"https://pubmed.ncbi.nlm.nih.gov/1731893"},"language":"en","primary_location":{"id":"doi:10.1021/bi00117a008","doi":"https://doi.org/10.1021/bi00117a008","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi00117a008","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019132119","display_name":"James V. Brawley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James V. Brawley","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of California, Los Angeles 90024"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of California, Los Angeles 90024","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072578902","display_name":"Harold G. Martinson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Harold G. Martinson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.8885,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.70649551,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"31","issue":"2","first_page":"364","last_page":"370"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/histone-h3","display_name":"histone H3","score":0.902999997138977},{"id":"https://openalex.org/keywords/nucleosome-core-particle","display_name":"nucleosome core particle","score":0.8320000171661377},{"id":"https://openalex.org/keywords/protein-protein-cross-linking","display_name":"protein-protein cross-linking","score":0.6769999861717224},{"id":"https://openalex.org/keywords/nucleosome-dyad","display_name":"nucleosome dyad","score":0.6460000276565552},{"id":"https://openalex.org/keywords/sulfhydryl-groups","display_name":"sulfhydryl groups","score":0.7799999713897705},{"id":"https://openalex.org/keywords/chromatin-structure","display_name":"chromatin structure","score":0.3709999918937683}],"concepts":[{"id":"https://openalex.org/C2778447006","wikidata":"https://www.wikidata.org/wiki/Q1156474","display_name":"Icon","level":2,"score":0.6957153081893921},{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.5900682210922241},{"id":"https://openalex.org/C84772758","wikidata":"https://www.wikidata.org/wiki/Q271794","display_name":"Nucleosome","level":4,"score":0.5495683550834656},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5369541049003601},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.5079622864723206},{"id":"https://openalex.org/C2164484","wikidata":"https://www.wikidata.org/wiki/Q5170150","display_name":"Core (optical fiber)","level":2,"score":0.47210636734962463},{"id":"https://openalex.org/C518677369","wikidata":"https://www.wikidata.org/wiki/Q202833","display_name":"Social media","level":2,"score":0.4256621301174164},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.39606156945228577},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.36969679594039917},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.27033478021621704},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.14239531755447388},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12941411137580872},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.10795217752456665},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10006284713745117},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001386","descriptor_name":"Azides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003432","descriptor_name":"Cross-Linking Reagents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006609","descriptor_name":"High Mobility Group Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010449","descriptor_name":"Peptide Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010782","descriptor_name":"Photolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/bi00117a008","doi":"https://doi.org/10.1021/bi00117a008","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi00117a008","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},{"id":"pmid:1731893","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1731893","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2672718490","display_name":null,"funder_award_id":"1S10RR05554-01","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G3063611300","display_name":"SECOND GENERATION PROTEIN SEQUENCER","funder_award_id":"1S10RR005554-01","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G3599288430","display_name":"GENOMIC DOMAINS AND TOPOISOMERASES IN GENE REGULATION","funder_award_id":"5r01gm035750-05","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G406254060","display_name":null,"funder_award_id":"GM 35750","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1480135811","https://openalex.org/W1529933594","https://openalex.org/W1531377584","https://openalex.org/W1545939286","https://openalex.org/W1565591380","https://openalex.org/W1598561175","https://openalex.org/W1621796013","https://openalex.org/W1964313477","https://openalex.org/W1966516101","https://openalex.org/W1975085160","https://openalex.org/W1979602017","https://openalex.org/W1984769155","https://openalex.org/W1988008377","https://openalex.org/W1989564802","https://openalex.org/W2021717172","https://openalex.org/W2023928518","https://openalex.org/W2026113119","https://openalex.org/W2033244608","https://openalex.org/W2035727353","https://openalex.org/W2046225458","https://openalex.org/W2054348877","https://openalex.org/W2062227698","https://openalex.org/W2064190497","https://openalex.org/W2065367918","https://openalex.org/W2069487375","https://openalex.org/W2128318390","https://openalex.org/W2134741288","https://openalex.org/W2170033713","https://openalex.org/W2219307397"],"related_works":["https://openalex.org/W1990170899","https://openalex.org/W1531377584","https://openalex.org/W1991614012","https://openalex.org/W4251855597","https://openalex.org/W1598561175","https://openalex.org/W2077671872","https://openalex.org/W2047529459","https://openalex.org/W1988008377","https://openalex.org/W1983056003","https://openalex.org/W2046225458"],"abstract_inverted_index":{"HMG":[0,62],"proteins":[1,63],"were":[2],"derivatized":[3],"with":[4,15,54],"the":[5,24,39,58,73,77,81,90,96],"photoactivatable":[6],"cross-linker":[7],"N-succinimidyl":[8],"3-((4-azidophenyl)dithio)propionate":[9],"and":[10,65,86],"then":[11],"allowed":[12],"to":[13,41,70],"associate":[14],"nucleosome":[16],"core":[17],"particles.":[18],"Following":[19],"photolysis,":[20],"peptide":[21],"mapping":[22],"of":[23,49,76,99],"principal":[25],"dimeric":[26],"adducts":[27],"was":[28],"carried":[29],"out.":[30],"Cross-linking":[31],"occurred":[32],"primarily":[33],"from":[34,57],"a":[35,42],"central":[36,43],"location":[37,44],"in":[38,45,89],"HMGs":[40,84],"H3.":[46],"The":[47],"positions":[48],"these":[50],"cross-links,":[51],"considered":[52],"along":[53],"other":[55],"data":[56],"literature,":[59],"show":[60],"that":[61,83],"14":[64,85],"17":[66,87],"make":[67],"important":[68],"contacts":[69],"H3":[71,97],"near":[72],"front":[74],"face":[75],"nucleosome.":[78],"This":[79],"raises":[80],"possibility":[82],"participate":[88],"reported":[91],"conformational":[92],"transition":[93],"which":[94],"exposes":[95],"sulfhydryls":[98],"active":[100],"nucleosomes.":[101]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}