{"id":"https://openalex.org/W1991985237","doi":"https://doi.org/10.2138/rmg.2006.64.8","title":"Bone: Nature of the Calcium Phosphate Crystals and Cellular, Structural, and Physical Chemical Mechanisms in Their Formation","display_name":"Bone: Nature of the Calcium Phosphate Crystals and Cellular, Structural, and Physical Chemical Mechanisms in Their Formation","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W1991985237","doi":"https://doi.org/10.2138/rmg.2006.64.8","mag":"1991985237"},"language":"en","primary_location":{"id":"doi:10.2138/rmg.2006.64.8","doi":"https://doi.org/10.2138/rmg.2006.64.8","is_oa":false,"landing_page_url":"https://doi.org/10.2138/rmg.2006.64.8","pdf_url":null,"source":{"id":"https://openalex.org/S4210187442","display_name":"Reviews in Mineralogy and Geochemistry","issn_l":"1529-6466","issn":["1529-6466","1943-2666"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-2","norway-1"],"host_organization":"https://openalex.org/P4310319932","host_organization_name":"Mineralogical Society of America","host_organization_lineage":["https://openalex.org/P4310319932"],"host_organization_lineage_names":["Mineralogical Society of America"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reviews in Mineralogy and Geochemistry","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1991985237"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108437170","display_name":"Melvin J. Glimcher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"M. J. Glimcher","raw_affiliation_strings":["Laboratory for the Study of Skeletal Disorders and Rehabilitation, Department of Orthopaedic Surgery, Harvard Medical School and Children\u2019s Hospital, Boston, Massachusetts, 02115, U.S.A., e-mail:"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for the Study of Skeletal Disorders and Rehabilitation, Department of Orthopaedic Surgery, Harvard Medical School and Children\u2019s Hospital, Boston, Massachusetts, 02115, U.S.A., e-mail:","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5108437170"],"corresponding_institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I136199984"],"apc_list":null,"apc_paid":null,"fwci":4.7771,"has_fulltext":false,"cited_by_count":341,"citation_normalized_percentile":{"value":0.94978895,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"64","issue":"1","first_page":"223","last_page":"282"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.36039999127388,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.36039999127388,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13453","display_name":"Alkaline Phosphatase Research Studies","score":0.2761000096797943,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12110","display_name":"Bone and Dental Protein Studies","score":0.179299995303154,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calcium-phosphate","display_name":"calcium phosphate","score":0.8420000076293945},{"id":"https://openalex.org/keywords/bone-mineral","display_name":"bone mineral","score":0.6380000114440918},{"id":"https://openalex.org/keywords/biomineralization","display_name":"biomineralization","score":0.9259999990463257},{"id":"https://openalex.org/keywords/crystal-structure","display_name":"crystal structure","score":0.6629999876022339},{"id":"https://openalex.org/keywords/mineral-formation-mechanism","display_name":"mineral formation mechanism","score":0.5789999961853027},{"id":"https://openalex.org/keywords/bone-resorption","display_name":"bone resorption","score":0.5370000004768372},{"id":"https://openalex.org/keywords/bone-remodeling","display_name":"bone remodeling","score":0.5170000195503235},{"id":"https://openalex.org/keywords/dental-tissues","display_name":"dental tissues","score":0.35899999737739563},{"id":"https://openalex.org/keywords/skeletal-tissue","display_name":"skeletal tissue","score":0.3540000021457672}],"concepts":[{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.6976287961006165},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.5310846567153931},{"id":"https://openalex.org/C2778447006","wikidata":"https://www.wikidata.org/wiki/Q1156474","display_name":"Icon","level":2,"score":0.46099284291267395},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.4477005898952484},{"id":"https://openalex.org/C111696902","wikidata":"https://www.wikidata.org/wiki/Q6864413","display_name":"Mineralization (soil science)","level":3,"score":0.4412012994289398},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4221377372741699},{"id":"https://openalex.org/C199289684","wikidata":"https://www.wikidata.org/wiki/Q83353","display_name":"Mineralogy","level":1,"score":0.34432029724121094},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3050817549228668},{"id":"https://openalex.org/C537208039","wikidata":"https://www.wikidata.org/wiki/Q627","display_name":"Nitrogen","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2138/rmg.2006.64.8","doi":"https://doi.org/10.2138/rmg.2006.64.8","is_oa":false,"landing_page_url":"https://doi.org/10.2138/rmg.2006.64.8","pdf_url":null,"source":{"id":"https://openalex.org/S4210187442","display_name":"Reviews in Mineralogy and Geochemistry","issn_l":"1529-6466","issn":["1529-6466","1943-2666"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-2","norway-1"],"host_organization":"https://openalex.org/P4310319932","host_organization_name":"Mineralogical Society of America","host_organization_lineage":["https://openalex.org/P4310319932"],"host_organization_lineage_names":["Mineralogical Society of America"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reviews in Mineralogy and Geochemistry","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":193,"referenced_works":["https://openalex.org/W31904675","https://openalex.org/W60004077","https://openalex.org/W96867450","https://openalex.org/W172817006","https://openalex.org/W190438226","https://openalex.org/W226243078","https://openalex.org/W633953874","https://openalex.org/W1480190538","https://openalex.org/W1535886804","https://openalex.org/W1559055432","https://openalex.org/W1576753890","https://openalex.org/W1591758750","https://openalex.org/W1752844820","https://openalex.org/W1775897120","https://openalex.org/W1778504633","https://openalex.org/W1813956380","https://openalex.org/W1964344251","https://openalex.org/W1964429775","https://openalex.org/W1965967087","https://openalex.org/W1966211159","https://openalex.org/W1967476074","https://openalex.org/W1969497587","https://openalex.org/W1970853795","https://openalex.org/W1972048324","https://openalex.org/W1972190722","https://openalex.org/W1972994595","https://openalex.org/W1973170341","https://openalex.org/W1973472520","https://openalex.org/W1975663935","https://openalex.org/W1975700741","https://openalex.org/W1976370207","https://openalex.org/W1976842902","https://openalex.org/W1978199478","https://openalex.org/W1978255912","https://openalex.org/W1979365147","https://openalex.org/W1981401588","https://openalex.org/W1982381283","https://openalex.org/W1983003080","https://openalex.org/W1984770143","https://openalex.org/W1984893870","https://openalex.org/W1985261798","https://openalex.org/W1987401179","https://openalex.org/W1989385157","https://openalex.org/W1990230620","https://openalex.org/W1990928683","https://openalex.org/W1991414521","https://openalex.org/W1991598648","https://openalex.org/W1992333027","https://openalex.org/W1992591531","https://openalex.org/W1992613549","https://openalex.org/W1994389982","https://openalex.org/W1994562481","https://openalex.org/W2000471781","https://openalex.org/W2000776785","https://openalex.org/W2002657799","https://openalex.org/W2002882589","https://openalex.org/W2004834641","https://openalex.org/W2004974226","https://openalex.org/W2005990056","https://openalex.org/W2006507876","https://openalex.org/W2006629115","https://openalex.org/W2007961680","https://openalex.org/W2008929290","https://openalex.org/W2008987576","https://openalex.org/W2010197729","https://openalex.org/W2012491203","https://openalex.org/W2012912790","https://openalex.org/W2014571318","https://openalex.org/W2015682679","https://openalex.org/W2018188826","https://openalex.org/W2018839559","https://openalex.org/W2019259661","https://openalex.org/W2020636038","https://openalex.org/W2020667613","https://openalex.org/W2021463761","https://openalex.org/W2022294251","https://openalex.org/W2023735187","https://openalex.org/W2025444271","https://openalex.org/W2026455923","https://openalex.org/W2026706144","https://openalex.org/W2026892242","https://openalex.org/W2027011904","https://openalex.org/W2027463768","https://openalex.org/W2027658970","https://openalex.org/W2030995263","https://openalex.org/W2031789143","https://openalex.org/W2032659134","https://openalex.org/W2033275398","https://openalex.org/W2033477350","https://openalex.org/W2033591617","https://openalex.org/W2034003223","https://openalex.org/W2034275429","https://openalex.org/W2035136850","https://openalex.org/W2035325071","https://openalex.org/W2035533814","https://openalex.org/W2036260259","https://openalex.org/W2037474646","https://openalex.org/W2037864461","https://openalex.org/W2039273045","https://openalex.org/W2039286595","https://openalex.org/W2042062769","https://openalex.org/W2042441164","https://openalex.org/W2042919801","https://openalex.org/W2043445443","https://openalex.org/W2045967367","https://openalex.org/W2046281498","https://openalex.org/W2047290184","https://openalex.org/W2049263992","https://openalex.org/W2049353054","https://openalex.org/W2049616107","https://openalex.org/W2049651689","https://openalex.org/W2054083483","https://openalex.org/W2054482136","https://openalex.org/W2056085946","https://openalex.org/W2056995649","https://openalex.org/W2057004836","https://openalex.org/W2057881968","https://openalex.org/W2058579856","https://openalex.org/W2058622386","https://openalex.org/W2059659235","https://openalex.org/W2059783585","https://openalex.org/W2059943748","https://openalex.org/W2061166048","https://openalex.org/W2062374348","https://openalex.org/W2062972212","https://openalex.org/W2062979535","https://openalex.org/W2063914621","https://openalex.org/W2065079313","https://openalex.org/W2065269393","https://openalex.org/W2065788315","https://openalex.org/W2067620247","https://openalex.org/W2067878613","https://openalex.org/W2068521700","https://openalex.org/W2069616783","https://openalex.org/W2070465043","https://openalex.org/W2070975731","https://openalex.org/W2071899323","https://openalex.org/W2072066526","https://openalex.org/W2074052714","https://openalex.org/W2074538126","https://openalex.org/W2078983353","https://openalex.org/W2079282467","https://openalex.org/W2079705020","https://openalex.org/W2080157247","https://openalex.org/W2081742486","https://openalex.org/W2083030793","https://openalex.org/W2085306759","https://openalex.org/W2085445583","https://openalex.org/W2086049069","https://openalex.org/W2087026672","https://openalex.org/W2088889190","https://openalex.org/W2088964874","https://openalex.org/W2090533989","https://openalex.org/W2092055337","https://openalex.org/W2093662311","https://openalex.org/W2095451823","https://openalex.org/W2098692445","https://openalex.org/W2104235213","https://openalex.org/W2108152450","https://openalex.org/W2108886591","https://openalex.org/W2109208163","https://openalex.org/W2118770388","https://openalex.org/W2122531454","https://openalex.org/W2127053985","https://openalex.org/W2132044720","https://openalex.org/W2135339349","https://openalex.org/W2139458978","https://openalex.org/W2146957647","https://openalex.org/W2153867432","https://openalex.org/W2163402984","https://openalex.org/W2168950985","https://openalex.org/W2169170480","https://openalex.org/W2279998842","https://openalex.org/W2281017095","https://openalex.org/W2312294193","https://openalex.org/W2315761197","https://openalex.org/W2323129030","https://openalex.org/W2324009083","https://openalex.org/W2342300275","https://openalex.org/W2346551411","https://openalex.org/W2408838007","https://openalex.org/W2410585732","https://openalex.org/W2415805176","https://openalex.org/W2416353434","https://openalex.org/W2460636409","https://openalex.org/W2767155929","https://openalex.org/W2772905212","https://openalex.org/W2912230181","https://openalex.org/W3012452645","https://openalex.org/W3043719335","https://openalex.org/W4285719527","https://openalex.org/W4299979408","https://openalex.org/W4320995322"],"related_works":["https://openalex.org/W978382762","https://openalex.org/W4235958354","https://openalex.org/W2392919303","https://openalex.org/W2030345505","https://openalex.org/W1981442513","https://openalex.org/W3040664731","https://openalex.org/W2223302873","https://openalex.org/W4205474059","https://openalex.org/W765559729","https://openalex.org/W1998684805"],"abstract_inverted_index":{"Research":[0],"Article|":[1],"January":[2],"01,":[3],"2006":[4],"Bone:":[5,107],"Nature":[6,108],"of":[7,32,38,109,188,198,218,225,261,271],"the":[8,30,110,177,183,194,199,209,216,236,259,265,272],"Calcium":[9,111,174],"Phosphate":[10,112],"Crystals":[11,113],"and":[12,15,35,44,67,114,117,127,169,185,196,208,246,256,268],"Cellular,":[13,115],"Structural,":[14,116],"Physical":[16,118],"Chemical":[17,119],"Mechanisms":[18,120],"in":[19,65,121,125,167,206,228,242],"Their":[20,122],"Formation":[21],"Melvin":[22,25,104],"J.":[23,26,105],"Glimcher":[24,27],"Laboratory":[28],"for":[29,54],"Study":[31],"Skeletal":[33],"Disorders":[34],"Rehabilitation,":[36],"Department":[37],"Orthopaedic":[39],"Surgery,":[40],"Harvard":[41],"Medical":[42],"School":[43],"Children's":[45],"Hospital,":[46],"Boston,":[47],"Massachusetts,":[48],"02115,":[49],"U.S.A.,":[50],"e-mail:":[51],"Melvin.Glimcher@childrens.harvard.edu":[52],"Search":[53,101,150,157,171,173],"other":[55,269],"works":[56],"by":[57,258],"this":[58,219,280],"author":[59],"on:":[60],"GSW":[61],"Google":[62],"Scholar":[63],"Reviews":[64,124],"Mineralogy":[66,126,168],"Geochemistry":[68,128,170],"(2006)":[69],"64":[70,130],"(1):":[71,131],"223\u2013282.":[72,132],"https://doi.org/10.2138/rmg.2006.64.8":[73,134],"Article":[74],"history":[75],"first":[76],"online:":[77],"14":[78],"Jul":[79],"2017":[80],"Cite":[81],"View":[82],"This":[83,190],"Citation":[84,87,103],"Add":[85],"to":[86,214,233,279,284],"Manager":[88],"Share":[89,91],"Icon":[90,97],"Facebook":[92],"Twitter":[93],"LinkedIn":[94],"MailTo":[95],"Tools":[96,98],"Get":[99],"Permissions":[100],"Site":[102],"Glimcher;":[106],"Formation.":[123],"2006;;":[129],"doi:":[133],"Download":[135],"citation":[136],"file:":[137],"Ris":[138],"(Zotero)":[139],"Refmanager":[140],"EasyBib":[141],"Bookends":[142],"Mendeley":[143],"Papers":[144],"EndNote":[145],"RefWorks":[146],"BibTex":[147],"toolbar":[148,153],"search":[149,154,155,163],"Dropdown":[151],"Menu":[152],"input":[156,158],"auto":[159],"suggest":[160],"filter":[161],"your":[162,285],"All":[164],"ContentBy":[165],"SocietyReviews":[166],"Advanced":[172],"phosphate":[175],"is":[176,231,240,247,251],"dominant":[178],"solid":[179,200],"mineral":[180,238],"phase":[181,205,239],"within":[182],"skeletal":[184],"dental":[186],"tissues":[187],"vertebrates.":[189],"chapter":[191],"concentrates":[192],"on":[193],"structure":[195,267],"composition":[197],"calcium":[201],"inorganic":[202],"orthophosphate":[203],"(Ca\u2013Pi)":[204],"bone":[207],"mechanisms":[210],"that":[211,235,250],"are":[212],"thought":[213],"induce":[215],"onset":[217],"mineralization":[220,227],"process":[221],"as":[222],"an":[223],"example":[224],"biological":[226],"general.":[229],"It":[230],"important":[232],"recognize":[234],"Ca\u2013Pi":[237],"deposited":[241],"a":[243,248],"living":[244,262],"tissue":[245],"substance":[249],"continuously":[252],"being":[253],"synthesized,":[254],"resorbed":[255],"replaced":[257],"action":[260],"cells.":[263],"Therefore,":[264],"composition,":[266],"properties":[270],"solid...":[273],"You":[274],"do":[275],"not":[276],"have":[277,293],"access":[278],"content,":[281],"please":[282],"speak":[283],"institutional":[286],"administrator":[287],"if":[288],"you":[289,291],"feel":[290],"should":[292],"access.":[294]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":21},{"year":2023,"cited_by_count":20},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":23},{"year":2019,"cited_by_count":27},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":26},{"year":2016,"cited_by_count":23},{"year":2015,"cited_by_count":16},{"year":2014,"cited_by_count":22},{"year":2013,"cited_by_count":18},{"year":2012,"cited_by_count":19}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}