{"id":"https://openalex.org/W1991661756","doi":"https://doi.org/10.1002/uog.7221","title":"P16.04: Significance of 2.5-3.5 mm NT measurements","display_name":"P16.04: Significance of 2.5-3.5 mm NT measurements","publication_year":2009,"publication_date":"2009-09-01","ids":{"openalex":"https://openalex.org/W1991661756","doi":"https://doi.org/10.1002/uog.7221","mag":"1991661756"},"language":"en","primary_location":{"id":"doi:10.1002/uog.7221","doi":"https://doi.org/10.1002/uog.7221","is_oa":false,"landing_page_url":"https://doi.org/10.1002/uog.7221","pdf_url":null,"source":{"id":"https://openalex.org/S22881060","display_name":"Ultrasound in Obstetrics and Gynecology","issn_l":"0960-7692","issn":["0960-7692","1469-0705"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ultrasound in Obstetrics & Gynecology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063515615","display_name":"Andrejz Lysikiewicz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"A. Lysikiewicz","raw_affiliation_strings":["Obstetrics & Gynecology, Roosevelt Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Obstetrics & Gynecology, Roosevelt Hospital, New York, NY, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048358651","display_name":"Manal El Daouk","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. El-Daouk","raw_affiliation_strings":["Obstetrics & Gynecology, Roosevelt Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Obstetrics & Gynecology, Roosevelt Hospital, New York, NY, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054086166","display_name":"Lois E. Brustman","orcid":"https://orcid.org/0000-0001-5311-1984","observed_orcids":["https://orcid.org/0000-0001-5311-1984"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. Brustman","raw_affiliation_strings":["Obstetrics & Gynecology, Roosevelt Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Obstetrics & Gynecology, Roosevelt Hospital, New York, NY, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029855527","display_name":"Ronnie Sue Jaffe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Jaffe","raw_affiliation_strings":["Obstetrics & Gynecology, Roosevelt Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Obstetrics & Gynecology, Roosevelt Hospital, New York, NY, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074609201","display_name":"Oded Langer","orcid":"https://orcid.org/0000-0002-8101-3908","observed_orcids":["https://orcid.org/0000-0002-8101-3908"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"O. Langer","raw_affiliation_strings":["Obstetrics & Gynecology, Roosevelt Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Obstetrics & Gynecology, Roosevelt Hospital, New York, NY, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5063515615"],"corresponding_institution_ids":[],"apc_list":{"value":4940,"currency":"USD","value_usd":4940},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"34","issue":"S1","first_page":"238","last_page":"238"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11732","display_name":"Assisted Reproductive Technology and Twin Pregnancy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12552","display_name":"Fetal and Pediatric Neurological Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nuchal-translucency","display_name":"nuchal translucency","score":0.9929999709129333},{"id":"https://openalex.org/keywords/first-trimester-screening","display_name":"first-trimester screening","score":0.7720000147819519},{"id":"https://openalex.org/keywords/aneuploidy","display_name":"aneuploidy","score":0.8479999899864197},{"id":"https://openalex.org/keywords/down-syndrome","display_name":"Down syndrome","score":0.8629999756813049},{"id":"https://openalex.org/keywords/trisomy-13","display_name":"trisomy 13","score":0.8259999752044678},{"id":"https://openalex.org/keywords/adverse-pregnancy-outcomes","display_name":"adverse pregnancy outcomes","score":0.7770000100135803},{"id":"https://openalex.org/keywords/abortion","display_name":"abortion","score":0.6150000095367432},{"id":"https://openalex.org/keywords/sequential-screening","display_name":"sequential screening","score":0.4790000021457672},{"id":"https://openalex.org/keywords/chorionic-villus-sampling","display_name":"chorionic villus sampling","score":0.8629999756813049},{"id":"https://openalex.org/keywords/amniocentesis","display_name":"amniocentesis","score":0.9739999771118164},{"id":"https://openalex.org/keywords/genetic-counseling","display_name":"genetic counseling","score":0.5690000057220459}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9192027449607849},{"id":"https://openalex.org/C2777966818","wikidata":"https://www.wikidata.org/wiki/Q473768","display_name":"Amniocentesis","level":5,"score":0.8732550144195557},{"id":"https://openalex.org/C2776229224","wikidata":"https://www.wikidata.org/wiki/Q844903","display_name":"Trisomy","level":2,"score":0.7237399816513062},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.6501649022102356},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6267126798629761},{"id":"https://openalex.org/C2779672484","wikidata":"https://www.wikidata.org/wiki/Q529622","display_name":"Aneuploidy","level":4,"score":0.5994521379470825},{"id":"https://openalex.org/C2777943237","wikidata":"https://www.wikidata.org/wiki/Q2119430","display_name":"Diaphragmatic hernia","level":3,"score":0.5236132740974426},{"id":"https://openalex.org/C2778258057","wikidata":"https://www.wikidata.org/wiki/Q1136569","display_name":"Prenatal diagnosis","level":4,"score":0.4973335564136505},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.49093368649482727},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.40100592374801636},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.22497251629829407},{"id":"https://openalex.org/C2779096551","wikidata":"https://www.wikidata.org/wiki/Q133076","display_name":"Hernia","level":2,"score":0.15069305896759033},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.09046635031700134},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/uog.7221","doi":"https://doi.org/10.1002/uog.7221","is_oa":false,"landing_page_url":"https://doi.org/10.1002/uog.7221","pdf_url":null,"source":{"id":"https://openalex.org/S22881060","display_name":"Ultrasound in Obstetrics and Gynecology","issn_l":"0960-7692","issn":["0960-7692","1469-0705"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ultrasound in Obstetrics & Gynecology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3037912271","https://openalex.org/W2013200578","https://openalex.org/W2149556040","https://openalex.org/W4417094616","https://openalex.org/W2022416052","https://openalex.org/W2051225723","https://openalex.org/W1977312504","https://openalex.org/W1505365480","https://openalex.org/W2944375807","https://openalex.org/W3111672570"],"abstract_inverted_index":{"To":[0],"report":[1],"significance":[2],"of":[3,27,30,38,41,47,56,102,189,237],"2.5\u20133.5":[4,21,99,218],"mm":[5,22,219],"NT":[6,18,42,96,216],"measurements.":[7],"In":[8,167],"First":[9],"Trimester":[10],"Ultrasound":[11],"Screening":[12],"for":[13,225],"Aneuploidy":[14],"program,":[15],"patients":[16,35,69,88,94,106],"with":[17,83,175,186,222],"measurements":[19,43,217],"within":[20,98],"where":[23],"identified":[24],"and":[25,50,59,63,78,118,158,198,206],"analysis":[26],"the":[28,39,45,48,68],"outcome":[29],"pregnancy":[31,227],"was":[32],"performed.":[33],"All":[34,164],"were":[36,65,75,127,171],"informed":[37],"result":[40],"at":[44,192],"time":[46],"test":[49],"received":[51],"genetic":[52,71],"counseling":[53],"regarding":[54],"options":[55],"sequential":[57,110],"screening":[58,92],"risk":[60,224],"assessment.":[61],"CVS":[62,121],"amniocentesis":[64,117,124],"available":[66],"to":[67,108,173,184],"requesting":[70],"diagnosis.":[72],"Pregnancy":[73],"outcomes":[74,209],"then":[76],"followed":[77,122],"compared":[79],"between":[80],"groups":[81],"managed":[82],"diagnostic":[84],"modalities.":[85],"Among":[86],"3309":[87],"undergoing":[89],"first":[90],"trimester":[91],"48":[93],"had":[95,120],"measured":[97],"mm.":[100],"Out":[101],"this":[103,136],"number":[104],"20":[105],"elected":[107],"complete":[109],"screen,":[111],"18":[112],"have":[113],"chosen":[114],"CVS,":[115],"8":[116],"2":[119],"by":[123,204],"(mosaic).":[125],"There":[126],"total":[128,176],"7":[129],"major":[130],"fetal":[131,230],"abnormalities":[132],"detected,":[133],"found":[134],"in":[135,235],"groups:":[137],"3":[138],"trisomy":[139,144,149],"21":[140,145],"(by":[141,146,151,156,162],"CVS),":[142,152],"1":[143,148,153,159],"amniocentesis),":[147],"13":[150],"diaphragmatic":[154],"hernia":[155],"US)":[157],"duodenal":[160],"atresia":[161],"US).":[163],"underwent":[165],"TOP.":[166],"addition":[168],"two":[169,207],"pregnancies":[170,182,195,208],"lost":[172],"SAB":[174],"9":[177],"(19%)":[178],"unsuccessful":[179],"pregnancies.":[180],"35":[181],"progressed":[183],"term":[185],"good":[187],"outcome/delivery":[188],"healthy":[190],"neonates":[191],"term.":[193],"Two":[194],"are":[196],"well":[197],"on":[199],"going":[200],"(one":[201],"euploidy":[202],"confirmed":[203],"CVS)":[205],"remain":[210],"unknown.":[211],"Our":[212],"data":[213],"suggests":[214],"that":[215],"is":[220],"associated":[221],"increased":[223],"adverse":[226],"outcome.":[228],"Major":[229],"abnormality":[231],"can":[232],"be":[233],"diagnosed":[234],"19%":[236],"those":[238],"patients.":[239]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}