{"id":"https://openalex.org/W1991244575","doi":"https://doi.org/10.1620/tjem.162.261","title":"Serum Lp(a) lipoprotein concentrations of japanese patients with coronary heart disease.","display_name":"Serum Lp(a) lipoprotein concentrations of japanese patients with coronary heart disease.","publication_year":1990,"publication_date":"1990-01-01","ids":{"openalex":"https://openalex.org/W1991244575","doi":"https://doi.org/10.1620/tjem.162.261","mag":"1991244575","pmid":"https://pubmed.ncbi.nlm.nih.gov/2151070"},"language":"en","primary_location":{"id":"doi:10.1620/tjem.162.261","doi":"https://doi.org/10.1620/tjem.162.261","is_oa":true,"landing_page_url":"https://doi.org/10.1620/tjem.162.261","pdf_url":"https://www.jstage.jst.go.jp/article/tjem1920/162/3/162_3_261/_pdf","source":{"id":"https://openalex.org/S189069745","display_name":"The Tohoku Journal of Experimental Medicine","issn_l":"0040-8727","issn":["0040-8727","1349-3329"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310313307","host_organization_name":"Tohoku University","host_organization_lineage":["https://openalex.org/P4310313307"],"host_organization_lineage_names":["Tohoku University"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Tohoku Journal of Experimental Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/tjem1920/162/3/162_3_261/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"RYUICHI SANO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257744","display_name":"Yonezawa City Hospital","ror":"https://ror.org/05m88m864","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257744"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"RYUICHI SANO","raw_affiliation_strings":["Yonezawa City Hospital, Internal Medicine","Yonezawa City Hospital, Internal Medicine and Laboratory"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yonezawa City Hospital, Internal Medicine","institution_ids":["https://openalex.org/I4405257744"]},{"raw_affiliation_string":"Yonezawa City Hospital, Internal Medicine and Laboratory","institution_ids":["https://openalex.org/I4405257744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113640350","display_name":"Akihisa Fujino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257744","display_name":"Yonezawa City Hospital","ror":"https://ror.org/05m88m864","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257744"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"AKIHISA FUJINO","raw_affiliation_strings":["Yonezawa City Hospital, Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yonezawa City Hospital, Internal Medicine","institution_ids":["https://openalex.org/I4405257744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031610974","display_name":"Hiromichi Shimazu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257744","display_name":"Yonezawa City Hospital","ror":"https://ror.org/05m88m864","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257744"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"HIROMICHI SHIMAZU","raw_affiliation_strings":["Yonezawa City Hospital, Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yonezawa City Hospital, Internal Medicine","institution_ids":["https://openalex.org/I4405257744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102904383","display_name":"Masayoshi Kobayashi","orcid":"https://orcid.org/0000-0001-5830-1509","observed_orcids":["https://orcid.org/0000-0001-5830-1509"]},"institutions":[{"id":"https://openalex.org/I4405257744","display_name":"Yonezawa City Hospital","ror":"https://ror.org/05m88m864","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257744"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"MASAYOSHI KOBAYASHI","raw_affiliation_strings":["Yonezawa City Hospital, Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yonezawa City Hospital, Internal Medicine","institution_ids":["https://openalex.org/I4405257744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036025704","display_name":"Yoshikazu Yahata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257744","display_name":"Yonezawa City Hospital","ror":"https://ror.org/05m88m864","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257744"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"YOSHIKAZU YAHATA","raw_affiliation_strings":["Yonezawa City Hospital, Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yonezawa City Hospital, Internal Medicine","institution_ids":["https://openalex.org/I4405257744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008612216","display_name":"Atsuhiro Ogyuu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257744","display_name":"Yonezawa City Hospital","ror":"https://ror.org/05m88m864","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257744"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"ATSUHIRO OGYUU","raw_affiliation_strings":["Yonezawa City Hospital, Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yonezawa City Hospital, Internal Medicine","institution_ids":["https://openalex.org/I4405257744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101399187","display_name":"Katsunori Suzuki","orcid":"https://orcid.org/0000-0001-5977-9846","observed_orcids":["https://orcid.org/0000-0001-5977-9846"]},"institutions":[{"id":"https://openalex.org/I4405257744","display_name":"Yonezawa City Hospital","ror":"https://ror.org/05m88m864","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257744"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"KATSUNORI SUZUKI","raw_affiliation_strings":["Yonezawa City Hospital, Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yonezawa City Hospital, Internal Medicine","institution_ids":["https://openalex.org/I4405257744"]}]},{"author_position":"middle","author":{"id":null,"display_name":"MASAYUKI KITAGAWA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257744","display_name":"Yonezawa City Hospital","ror":"https://ror.org/05m88m864","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257744"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"MASAYUKI KITAGAWA","raw_affiliation_strings":["Yonezawa City Hospital, Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yonezawa City Hospital, Internal Medicine","institution_ids":["https://openalex.org/I4405257744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046211477","display_name":"Tsuneyoshi Saito","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257744","display_name":"Yonezawa City Hospital","ror":"https://ror.org/05m88m864","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257744"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TSUNEYOSHI SAITO","raw_affiliation_strings":["Yonezawa City Hospital, Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yonezawa City Hospital, Internal Medicine","institution_ids":["https://openalex.org/I4405257744"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057509254","display_name":"Hiroshi Inokuchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257744","display_name":"Yonezawa City Hospital","ror":"https://ror.org/05m88m864","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257744"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"HIROSHI INOKUCHI","raw_affiliation_strings":["Yonezawa City Hospital, Laboratory"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yonezawa City Hospital, Laboratory","institution_ids":["https://openalex.org/I4405257744"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4405257744"],"apc_list":null,"apc_paid":null,"fwci":0.3783,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.59183286,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"162","issue":"3","first_page":"261","last_page":"267"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipoprotein-a","display_name":"lipoprotein(a)","score":0.8980000019073486},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.7749999761581421},{"id":"https://openalex.org/keywords/coronary-stenosis","display_name":"coronary artery stenosis","score":0.8550000190734863},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.6899999976158142},{"id":"https://openalex.org/keywords/japanese-patients","display_name":"Japanese patients","score":0.7129999995231628}],"concepts":[{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.8189177513122559},{"id":"https://openalex.org/C2776104379","wikidata":"https://www.wikidata.org/wiki/Q21112670","display_name":"Lipoprotein(a)","level":4,"score":0.7971846461296082},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7940200567245483},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6505194902420044},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6058192849159241},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.5614672303199768},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.5269915461540222},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.5059539675712585},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3246380090713501},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.20650997757911682}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001053","descriptor_name":"Apolipoproteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003251","descriptor_name":"Constriction, Pathologic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017023","descriptor_name":"Coronary Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017270","descriptor_name":"Lipoprotein(a)","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1620/tjem.162.261","doi":"https://doi.org/10.1620/tjem.162.261","is_oa":true,"landing_page_url":"https://doi.org/10.1620/tjem.162.261","pdf_url":"https://www.jstage.jst.go.jp/article/tjem1920/162/3/162_3_261/_pdf","source":{"id":"https://openalex.org/S189069745","display_name":"The Tohoku Journal of Experimental Medicine","issn_l":"0040-8727","issn":["0040-8727","1349-3329"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310313307","host_organization_name":"Tohoku University","host_organization_lineage":["https://openalex.org/P4310313307"],"host_organization_lineage_names":["Tohoku University"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Tohoku Journal of Experimental Medicine","raw_type":"journal-article"},{"id":"pmid:2151070","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2151070","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Tohoku journal of experimental medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1620/tjem.162.261","doi":"https://doi.org/10.1620/tjem.162.261","is_oa":true,"landing_page_url":"https://doi.org/10.1620/tjem.162.261","pdf_url":"https://www.jstage.jst.go.jp/article/tjem1920/162/3/162_3_261/_pdf","source":{"id":"https://openalex.org/S189069745","display_name":"The Tohoku Journal of Experimental Medicine","issn_l":"0040-8727","issn":["0040-8727","1349-3329"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310313307","host_organization_name":"Tohoku University","host_organization_lineage":["https://openalex.org/P4310313307"],"host_organization_lineage_names":["Tohoku University"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Tohoku Journal of Experimental Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1991244575.pdf","grobid_xml":"https://content.openalex.org/works/W1991244575.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1972444318","https://openalex.org/W1986030167","https://openalex.org/W1992992795","https://openalex.org/W1994885000","https://openalex.org/W1998239323","https://openalex.org/W2004838889","https://openalex.org/W2012098057","https://openalex.org/W2019295985","https://openalex.org/W2035598300","https://openalex.org/W2040278638","https://openalex.org/W2048880173","https://openalex.org/W2058129900","https://openalex.org/W2070285262","https://openalex.org/W2083516336","https://openalex.org/W2116404316","https://openalex.org/W2149762754","https://openalex.org/W2280133490","https://openalex.org/W2411818145"],"related_works":["https://openalex.org/W2376729076","https://openalex.org/W2355617593","https://openalex.org/W4318263103","https://openalex.org/W2349496481","https://openalex.org/W2370473619","https://openalex.org/W7017307620","https://openalex.org/W2417325050","https://openalex.org/W645745332","https://openalex.org/W2940141657","https://openalex.org/W3030813225"],"abstract_inverted_index":{"The":[0,20],"serum":[1],"Lp(a)":[2,15,23,46,74,144,167],"lipoprotein":[3],"concentration":[4],"in":[5,24,48],"103":[6],"healthy":[7],"control":[8],"subjects":[9,50,59],"was":[10,27,55,87,122,146],"determined":[11],"by":[12],"ELISA":[13],"(TintElise":[14],"kit,":[16],"Biopool,":[17],"Umea,":[18],"Sweden).":[19],"distribution":[21],"of":[22,67,71,76,92,104,151],"the":[25,41,77,93,105,149],"controls":[26,106],"highly":[28],"skewed":[29],"(mean":[30,80,96],"132,":[31],"S.D.":[32,82,98],"109,":[33],"median":[34,84,100],"99":[35],"mg/liter),":[36],"which":[37],"is":[38],"similar":[39],"to":[40],"results":[42,164],"previously":[43],"reported.":[44],"Serum":[45],"level":[47,75,145],"104":[49],"who":[51],"underwent":[52],"coronary":[53,153,178],"angiography":[54],"also":[56],"measured.":[57],"These":[58,163],"were":[60],"divided":[61,123],"into":[62,124],"two":[63],"groups:":[64],"59":[65],"cases":[66],"stenosis(-)":[68,94],"and":[69,103,113,137],"45":[70],"stenosis(+)":[72,78,120],"groups.":[73],"group":[79,95,121],"235,":[81],"197,":[83],"159":[85],"mg/liter)":[86,102],"significantly":[88],"higher":[89],"than":[90,111,116,161],"that":[91,166],"156,":[97],"133,":[99],"123":[101],"(Wilcoxon":[107],"test,":[108],"p":[109,114,159],"less":[110,115,160],"0.05":[112],"0.01,":[117],"respectively).":[118],"Further,":[119],"three":[125],"subgroups:":[126],"20":[127],"with":[128,133,139,148],"single":[129],"vessel":[130,135,141],"disease,":[131],"13":[132],"double":[134],"disease":[136,142],"12":[138],"triple":[140],"subgroups.":[143],"correlated":[147],"number":[150],"stenotic":[152],"vessels":[154],"(Spearman's":[155],"rank":[156],"correlation":[157],"coefficient,":[158],"0.05).":[162],"suggest":[165],"may":[168],"play":[169],"an":[170],"important":[171],"part":[172],"as":[173],"a":[174],"risk":[175],"factor":[176],"for":[177],"heart":[179],"disease.":[180]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}