{"id":"https://openalex.org/W1991230253","doi":"https://doi.org/10.1007/bf02423457","title":"Identification ofStreptomyces violaceoruber T\u00fc22 genes involved in the biosynthesis of granaticin","display_name":"Identification ofStreptomyces violaceoruber T\u00fc22 genes involved in the biosynthesis of granaticin","publication_year":1995,"publication_date":"1995-09-01","ids":{"openalex":"https://openalex.org/W1991230253","doi":"https://doi.org/10.1007/bf02423457","mag":"1991230253","pmid":"https://pubmed.ncbi.nlm.nih.gov/7476861"},"language":"en","primary_location":{"id":"doi:10.1007/bf02423457","doi":"https://doi.org/10.1007/bf02423457","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02423457","pdf_url":null,"source":{"id":"https://openalex.org/S4210168070","display_name":"Molecular and General Genetics MGG","issn_l":"0026-8925","issn":["0026-8925","1432-1874"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and General Genetics MGG","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035577399","display_name":"Andreas Bechthold","orcid":"https://orcid.org/0000-0003-3594-6851","observed_orcids":["https://orcid.org/0000-0003-3594-6851"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andreas Bechthold","raw_affiliation_strings":["Department of Chemistry, University of Washington, Seattle 98195, USA","Department of Chemistry, University of Washington, 98195, Seattle, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Washington, Seattle 98195, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Chemistry, University of Washington, 98195, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062193992","display_name":"Jae Kyung Sohng","orcid":"https://orcid.org/0000-0003-1583-5046","observed_orcids":["https://orcid.org/0000-0003-1583-5046"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jae Kyung Sohng","raw_affiliation_strings":["Department of Chemistry, University of Washington, 98195, Seattle, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Washington, 98195, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086790161","display_name":"T. M. F. Smith","orcid":"https://orcid.org/0000-0002-6493-940X","observed_orcids":["https://orcid.org/0000-0002-6493-940X"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Todd M. Smith","raw_affiliation_strings":["Department of Medicinal Chemistry, University of Washington, 98195, Seattle, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry, University of Washington, 98195, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xin Chu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xin Chu","raw_affiliation_strings":["Department of Chemistry, University of Washington, 98195, Seattle, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Washington, 98195, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027410094","display_name":"Heinz G. Floss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heinz G. Floss","raw_affiliation_strings":["Department of Chemistry, University of Washington, 98195, Seattle, WA, USA","Department of Medicinal Chemistry, University of Washington, 98195, Seattle, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Washington, 98195, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Medicinal Chemistry, University of Washington, 98195, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":null,"apc_paid":null,"fwci":3.5828,"has_fulltext":false,"cited_by_count":54,"citation_normalized_percentile":{"value":0.9299569,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"248","issue":"5","first_page":"610","last_page":"620"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12673","display_name":"Microbial Metabolism and Applications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/streptomyces-violaceoruber","display_name":"Streptomyces violaceoruber","score":0.9259999990463257},{"id":"https://openalex.org/keywords/granaticin","display_name":"granaticin","score":0.9150000214576721},{"id":"https://openalex.org/keywords/polyketide-biosynthesis","display_name":"polyketide biosynthesis","score":0.7630000114440918},{"id":"https://openalex.org/keywords/efflux-pumps","display_name":"efflux pumps","score":0.5630000233650208},{"id":"https://openalex.org/keywords/tetracycline-resistance","display_name":"tetracycline resistance","score":0.796999990940094},{"id":"https://openalex.org/keywords/gene-identification","display_name":"gene identification","score":0.6269999742507935},{"id":"https://openalex.org/keywords/open-reading-frames","display_name":"open reading frames","score":0.7519999742507935},{"id":"https://openalex.org/keywords/streptomyces-griseus","display_name":"Streptomyces griseus","score":0.8880000114440918}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8931431770324707},{"id":"https://openalex.org/C2780873923","wikidata":"https://www.wikidata.org/wiki/Q7623385","display_name":"Streptomyces griseus","level":4,"score":0.8350653648376465},{"id":"https://openalex.org/C2781374117","wikidata":"https://www.wikidata.org/wiki/Q5252382","display_name":"Dehydratase","level":3,"score":0.6698830127716064},{"id":"https://openalex.org/C47289529","wikidata":"https://www.wikidata.org/wiki/Q908550","display_name":"Open reading frame","level":4,"score":0.6138583421707153},{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.5847760438919067},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5605719089508057},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.532362699508667},{"id":"https://openalex.org/C84148353","wikidata":"https://www.wikidata.org/wiki/Q863908","display_name":"Nucleic acid sequence","level":3,"score":0.5243009328842163},{"id":"https://openalex.org/C2780530800","wikidata":"https://www.wikidata.org/wiki/Q7072921","display_name":"ORFS","level":5,"score":0.4965820908546448},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4673139452934265},{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.44679075479507446},{"id":"https://openalex.org/C2779920670","wikidata":"https://www.wikidata.org/wiki/Q1144013","display_name":"Streptomyces","level":3,"score":0.4233302175998688},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3989821672439575},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.39881980419158936},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.12887859344482422}],"mesh":[{"descriptor_ui":"D000095622","descriptor_name":"Benzoisochromanequinones","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005798","descriptor_name":"Genes, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009285","descriptor_name":"Naphthoquinones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013302","descriptor_name":"Streptomyces","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D013302","descriptor_name":"Streptomyces","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017421","descriptor_name":"Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf02423457","doi":"https://doi.org/10.1007/bf02423457","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02423457","pdf_url":null,"source":{"id":"https://openalex.org/S4210168070","display_name":"Molecular and General Genetics MGG","issn_l":"0026-8925","issn":["0026-8925","1432-1874"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and General Genetics MGG","raw_type":"journal-article"},{"id":"pmid:7476861","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7476861","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular & general genetics : MGG","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1076543508","display_name":null,"funder_award_id":"GM 43345","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G632557284","display_name":null,"funder_award_id":"GM-07750","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6430891267","display_name":"BIOSYNTHESIS OF 2,6 DIDEOXYHEXOSES","funder_award_id":"5r01gm043345-05","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7443692255","display_name":"Drug Action, Metabolism and Kinetics Training Grant","funder_award_id":"T32GM007750","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1259650361","https://openalex.org/W1489868419","https://openalex.org/W1525483941","https://openalex.org/W1532591176","https://openalex.org/W1558365920","https://openalex.org/W1559082863","https://openalex.org/W1559427338","https://openalex.org/W1570466907","https://openalex.org/W1571659342","https://openalex.org/W1971064082","https://openalex.org/W1989376656","https://openalex.org/W1994441123","https://openalex.org/W1995995599","https://openalex.org/W2000386834","https://openalex.org/W2002684744","https://openalex.org/W2009310436","https://openalex.org/W2025603165","https://openalex.org/W2028622989","https://openalex.org/W2029590297","https://openalex.org/W2039606000","https://openalex.org/W2048512524","https://openalex.org/W2058100398","https://openalex.org/W2058252407","https://openalex.org/W2065018402","https://openalex.org/W2079905424","https://openalex.org/W2080946546","https://openalex.org/W2081652281","https://openalex.org/W2090988351","https://openalex.org/W2101190117","https://openalex.org/W2135967789","https://openalex.org/W2144634347","https://openalex.org/W2164527823","https://openalex.org/W2230655792","https://openalex.org/W2246656981","https://openalex.org/W2314225431"],"related_works":["https://openalex.org/W2076416249","https://openalex.org/W2021393956","https://openalex.org/W1989857762","https://openalex.org/W2053540548","https://openalex.org/W2048512524","https://openalex.org/W1976721501","https://openalex.org/W3116318675","https://openalex.org/W782653446","https://openalex.org/W2387276727","https://openalex.org/W2119286677"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}