{"id":"https://openalex.org/W1991114474","doi":"https://doi.org/10.1089/jmf.2010.0187","title":"Differential Antioxidant Effects of Consuming Tea from Sideritis clandestina subsp. peloponnesiaca on Cerebral Regions of Adult Mice","display_name":"Differential Antioxidant Effects of Consuming Tea from Sideritis clandestina subsp. peloponnesiaca on Cerebral Regions of Adult Mice","publication_year":2011,"publication_date":"2011-04-11","ids":{"openalex":"https://openalex.org/W1991114474","doi":"https://doi.org/10.1089/jmf.2010.0187","mag":"1991114474","pmid":"https://pubmed.ncbi.nlm.nih.gov/21480805"},"language":"en","primary_location":{"id":"doi:10.1089/jmf.2010.0187","doi":"https://doi.org/10.1089/jmf.2010.0187","is_oa":false,"landing_page_url":"https://doi.org/10.1089/jmf.2010.0187","pdf_url":null,"source":{"id":"https://openalex.org/S78718175","display_name":"Journal of Medicinal Food","issn_l":"1096-620X","issn":["1096-620X","1557-7600"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","kci-registered","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Food","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048378801","display_name":"Zacharoula I. Linardaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Zacharoula I. Linardaki","raw_affiliation_strings":["University of Patras","Laboratory of Human and Animal Physiology, Department of Biology, University of Patras, Patras, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Patras","institution_ids":["https://openalex.org/I174878644"]},{"raw_affiliation_string":"Laboratory of Human and Animal Physiology, Department of Biology, University of Patras, Patras, Greece","institution_ids":["https://openalex.org/I174878644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017693247","display_name":"Catherine G. Vasilopoulou","orcid":"https://orcid.org/0000-0002-6622-1979","observed_orcids":["https://orcid.org/0000-0002-6622-1979"]},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Catherine G. Vasilopoulou","raw_affiliation_strings":["University of Patras","Laboratory of Human and Animal Physiology, Department of Biology, University of Patras, Patras, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Patras","institution_ids":["https://openalex.org/I174878644"]},{"raw_affiliation_string":"Laboratory of Human and Animal Physiology, Department of Biology, University of Patras, Patras, Greece","institution_ids":["https://openalex.org/I174878644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075140778","display_name":"Caterina Constantinou","orcid":"https://orcid.org/0000-0003-3589-0739","observed_orcids":["https://orcid.org/0000-0003-3589-0739"]},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Caterina Constantinou","raw_affiliation_strings":["University of Patras","Laboratory of Human and Animal Physiology, Department of Biology, University of Patras, Patras, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Patras","institution_ids":["https://openalex.org/I174878644"]},{"raw_affiliation_string":"Laboratory of Human and Animal Physiology, Department of Biology, University of Patras, Patras, Greece","institution_ids":["https://openalex.org/I174878644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052940239","display_name":"Gregoris Iatro\u00fa","orcid":"https://orcid.org/0000-0001-9575-8524","observed_orcids":["https://orcid.org/0000-0001-9575-8524"]},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Gregoris Iatrou","raw_affiliation_strings":["University of Patras","Division of Plant Biology, Department of Biology, University of Patras, Patras, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Patras","institution_ids":["https://openalex.org/I174878644"]},{"raw_affiliation_string":"Division of Plant Biology, Department of Biology, University of Patras, Patras, Greece","institution_ids":["https://openalex.org/I174878644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041852809","display_name":"Fotini N. Lamari","orcid":"https://orcid.org/0000-0002-6938-3500","observed_orcids":["https://orcid.org/0000-0002-6938-3500"]},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Fotini N. Lamari","raw_affiliation_strings":["University of Patras","Laboratory of Pharmacognosy & Chemistry of Natural Products, Department of Pharmacy, University of Patras, Patras, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Patras","institution_ids":["https://openalex.org/I174878644"]},{"raw_affiliation_string":"Laboratory of Pharmacognosy & Chemistry of Natural Products, Department of Pharmacy, University of Patras, Patras, Greece","institution_ids":["https://openalex.org/I174878644"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028257697","display_name":"Marigoula Margarity","orcid":"https://orcid.org/0000-0002-5429-3465","observed_orcids":["https://orcid.org/0000-0002-5429-3465"]},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Marigoula Margarity","raw_affiliation_strings":["University of Patras","Laboratory of Human and Animal Physiology, Department of Biology, University of Patras, Patras, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Patras","institution_ids":["https://openalex.org/I174878644"]},{"raw_affiliation_string":"Laboratory of Human and Animal Physiology, Department of Biology, University of Patras, Patras, Greece","institution_ids":["https://openalex.org/I174878644"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5028257697"],"corresponding_institution_ids":["https://openalex.org/I174878644"],"apc_list":null,"apc_paid":null,"fwci":0.7609,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.65470452,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"14","issue":"9","first_page":"1060","last_page":"1064"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.01510000042617321,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11411","display_name":"Tea Polyphenols and Effects","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mountain-tea","display_name":"mountain tea","score":0.8769999742507935},{"id":"https://openalex.org/keywords/herbal-tea","display_name":"herbal tea","score":0.6140000224113464},{"id":"https://openalex.org/keywords/antioxidant-status","display_name":"antioxidant status","score":0.6050000190734863},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9810000061988831},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.800000011920929},{"id":"https://openalex.org/keywords/brain-regions","display_name":"brain regions","score":0.6790000200271606},{"id":"https://openalex.org/keywords/cerebral-cortex","display_name":"cerebral cortex","score":0.6209999918937683},{"id":"https://openalex.org/keywords/cerebellum","display_name":"cerebellum","score":0.9929999709129333},{"id":"https://openalex.org/keywords/midbrain","display_name":"midbrain","score":1.0},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.906000018119812},{"id":"https://openalex.org/keywords/reduced-glutathione","display_name":"reduced glutathione","score":0.902999997138977},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.968999981880188},{"id":"https://openalex.org/keywords/polyphenols","display_name":"polyphenols","score":0.9079999923706055},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.7680000066757202},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.6470000147819519},{"id":"https://openalex.org/keywords/dietary-supplementation","display_name":"dietary supplementation","score":0.5070000290870667}],"concepts":[{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.7482936978340149},{"id":"https://openalex.org/C2778401633","wikidata":"https://www.wikidata.org/wiki/Q418661","display_name":"Malondialdehyde","level":3,"score":0.7287277579307556},{"id":"https://openalex.org/C70899900","wikidata":"https://www.wikidata.org/wiki/Q290439","display_name":"Polyphenol","level":3,"score":0.6140530109405518},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.599601686000824},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.5549893975257874},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.5474609732627869},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.4102303385734558},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4096829295158386},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3937166631221771},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3683260381221771},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3489668369293213},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.206222265958786},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001628","descriptor_name":"Beverages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005978","descriptor_name":"Glutathione","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008315","descriptor_name":"Malondialdehyde","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008636","descriptor_name":"Mesencephalon","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018547","descriptor_name":"Plant Stems","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D031365","descriptor_name":"Sideritis","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D035264","descriptor_name":"Flowers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059808","descriptor_name":"Polyphenols","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1089/jmf.2010.0187","doi":"https://doi.org/10.1089/jmf.2010.0187","is_oa":false,"landing_page_url":"https://doi.org/10.1089/jmf.2010.0187","pdf_url":null,"source":{"id":"https://openalex.org/S78718175","display_name":"Journal of Medicinal Food","issn_l":"1096-620X","issn":["1096-620X","1557-7600"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","kci-registered","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Food","raw_type":"journal-article"},{"id":"pmid:21480805","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21480805","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medicinal food","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1914622032","https://openalex.org/W1970742438","https://openalex.org/W1975001459","https://openalex.org/W1976865303","https://openalex.org/W1988819044","https://openalex.org/W1998936301","https://openalex.org/W2007658546","https://openalex.org/W2021233691","https://openalex.org/W2038118231","https://openalex.org/W2040455245","https://openalex.org/W2044627978","https://openalex.org/W2056317998","https://openalex.org/W2059382716","https://openalex.org/W2070018632","https://openalex.org/W2072348601","https://openalex.org/W2073633365","https://openalex.org/W2076123692","https://openalex.org/W2076371251","https://openalex.org/W2099556643","https://openalex.org/W2109561041","https://openalex.org/W2114004260","https://openalex.org/W2124220561","https://openalex.org/W2128635872","https://openalex.org/W2133387761","https://openalex.org/W2139042797","https://openalex.org/W2141974801","https://openalex.org/W2152381240","https://openalex.org/W2171626661"],"related_works":["https://openalex.org/W2014646226","https://openalex.org/W2076170698","https://openalex.org/W2760551277","https://openalex.org/W1919979990","https://openalex.org/W2054905608","https://openalex.org/W2091970981","https://openalex.org/W2392429586","https://openalex.org/W2046599839","https://openalex.org/W2937752332","https://openalex.org/W1970334266"],"abstract_inverted_index":{"Oxidative":[0],"stress":[1],"is":[2],"involved":[3],"in":[4,23,92,140,154,184,189,225],"the":[5,15,24,33,48,57,62,68,86,105,114,117,122,129,141,170,175,194,217,221],"pathophysiology":[6],"of":[7,14,35,37,51,79,85,116,131,134,165,174,193,220],"neurodegenerative":[8],"diseases":[9],"and":[10,67,76,82,128,137,145,187,197,200,203],"aging.":[11],"Many":[12],"species":[13],"genus":[16],"Sideritis":[17,43],"(mountain":[18],"tea)":[19],"are":[20],"widely":[21],"consumed":[22],"Mediterranean":[25],"region":[26],"as":[27,158],"herbal":[28,40,60,106,167],"tea.":[29],"This":[30],"study":[31],"evaluated":[32],"effect":[34],"supplementation":[36],"mice":[38,96],"with":[39],"tea":[41,107,168,214],"from":[42],"clandestina":[44,88],"subsp.":[45],"peloponnesiaca":[46],"on":[47],"antioxidant":[49,69,73,124,172,218],"status":[50],"different":[52,83],"brain":[53,224],"regions.":[54],"To":[55],"select":[56],"most":[58],"bioactive":[59],"tea,":[61],"polyphenolic":[63],"content":[64,192],"(Folin-Ciocalteu":[65],"method)":[66],"properties":[70],"(ferric":[71],"reducing":[72],"power":[74,125,173],"[FRAP]":[75],"2,2-diphenyl-1-picrylhydrazyl":[77],"assays)":[78],"several":[80],"taxa":[81],"populations":[84],"S.":[87],"infusions":[89],"were":[90,206],"measured":[91],"vitro.":[93],"Male":[94],"adult":[95,222],"had":[97],"ad":[98],"libitum":[99],"access":[100],"to":[101],"water":[102],"(control)":[103],"or":[104],"(4%":[108],"w/v)":[109],"for":[110],"6":[111],"weeks.":[112],"At":[113],"end":[115],"treatment":[118],"period":[119],"we":[120],"assessed":[121],"total":[123,171],"(FRAP":[126],"assay)":[127],"levels":[130,186],"malondialdehyde":[132,185],"(indicator":[133],"lipid":[135],"peroxidation)":[136],"reduced":[138,190],"glutathione":[139,191],"cerebral":[142],"cortex,":[143],"cerebellum,":[144],"midbrain.":[146],"These":[147,209],"biochemical":[148],"measures":[149],"have":[150],"also":[151,207],"been":[152],"determined":[153],"liver":[155],"samples":[156],"used":[157],"a":[159,180,226],"comparative":[160],"reference":[161],"peripheral":[162],"tissue.":[163],"Consumption":[164],"4%":[166],"increased":[169],"midbrain":[176,201],"by":[177],"72%":[178],"(P<.05);":[179],"significant":[181],"(P<.05)":[182],"decrease":[183],"increase":[188],"cerebellum":[195],"(78%":[196],"27%,":[198],"respectively)":[199,205],"(59%":[202],"32%,":[204],"observed.":[208],"findings":[210],"indicate":[211],"that":[212],"mountain":[213],"consumption":[215],"enhances":[216],"defense":[219],"rodent":[223],"region-specific":[227],"manner.":[228]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}