{"id":"https://openalex.org/W1990952440","doi":"https://doi.org/10.1016/s0920-1211(02)00063-3","title":"New horizons in the development of antiepileptic drugs","display_name":"New horizons in the development of antiepileptic drugs","publication_year":2002,"publication_date":"2002-06-01","ids":{"openalex":"https://openalex.org/W1990952440","doi":"https://doi.org/10.1016/s0920-1211(02)00063-3","mag":"1990952440","pmid":"https://pubmed.ncbi.nlm.nih.gov/12151112"},"language":"en","primary_location":{"id":"doi:10.1016/s0920-1211(02)00063-3","doi":"https://doi.org/10.1016/s0920-1211(02)00063-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0920-1211(02)00063-3","pdf_url":null,"source":{"id":"https://openalex.org/S144140688","display_name":"Epilepsy Research","issn_l":"0920-1211","issn":["0920-1211","1872-6844"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy Research","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010235451","display_name":"Wolfgang L\u00f6scher","orcid":"https://orcid.org/0000-0002-9648-8973","observed_orcids":["https://orcid.org/0000-0002-9648-8973"]},"institutions":[{"id":"https://openalex.org/I189991","display_name":"University of Veterinary Medicine Hannover, Foundation","ror":"https://ror.org/015qjqf64","country_code":"DE","type":"education","lineage":["https://openalex.org/I189991"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Wolfgang L\u00f6scher","raw_affiliation_strings":["Department of Pharmacology, Toxicology and Pharmacy, School of Veterinary Medicine, Buenteweg 17, Hannover, Germany. wolfgang.loescher@tiho-hannover.de","Department of Pharmacology, Toxicology and Pharmacy, School of Veterinary Medicine, Buenteweg 17, D-30551 Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Toxicology and Pharmacy, School of Veterinary Medicine, Buenteweg 17, Hannover, Germany. wolfgang.loescher@tiho-hannover.de","institution_ids":["https://openalex.org/I189991"]},{"raw_affiliation_string":"Department of Pharmacology, Toxicology and Pharmacy, School of Veterinary Medicine, Buenteweg 17, D-30551 Hannover, Germany","institution_ids":["https://openalex.org/I189991"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108191251","display_name":"Dieter Schmidt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dieter Schmidt","raw_affiliation_strings":["Epilepsy Research Group, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epilepsy Research Group, Berlin, Germany","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5010235451"],"corresponding_institution_ids":["https://openalex.org/I189991"],"apc_list":{"value":2880,"currency":"USD","value_usd":2880},"apc_paid":null,"fwci":1.8731,"has_fulltext":false,"cited_by_count":130,"citation_normalized_percentile":{"value":0.86926606,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"50","issue":"1-2","first_page":"3","last_page":"16"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12267","display_name":"Diet and metabolism studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antiepileptic-drugs","display_name":"antiepileptic drugs","score":0.9919999837875366},{"id":"https://openalex.org/keywords/epilepsy","display_name":"epilepsy","score":0.8180000185966492},{"id":"https://openalex.org/keywords/drug-resistant-epilepsy","display_name":"drug-resistant epilepsy","score":0.8040000200271606},{"id":"https://openalex.org/keywords/pharmacoresistance","display_name":"pharmacoresistance","score":0.7210000157356262},{"id":"https://openalex.org/keywords/epilepsy-prevention","display_name":"epilepsy prevention","score":0.8399999737739563},{"id":"https://openalex.org/keywords/disease-modifying-therapy","display_name":"disease-modifying therapy","score":0.7200000286102295},{"id":"https://openalex.org/keywords/epilepsy-progression","display_name":"epilepsy progression","score":0.6600000262260437},{"id":"https://openalex.org/keywords/head-trauma","display_name":"head trauma","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.9154485464096069},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.680184006690979},{"id":"https://openalex.org/C2994127763","wikidata":"https://www.wikidata.org/wiki/Q576618","display_name":"Antiepileptic drug","level":3,"score":0.6049032211303711},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5654124021530151},{"id":"https://openalex.org/C500440147","wikidata":"https://www.wikidata.org/wiki/Q701216","display_name":"Pharmacotherapy","level":2,"score":0.5176525712013245},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4667769968509674},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.21520283818244934},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10887396335601807}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000927","descriptor_name":"Anticonvulsants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004351","descriptor_name":"Drug Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0920-1211(02)00063-3","doi":"https://doi.org/10.1016/s0920-1211(02)00063-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0920-1211(02)00063-3","pdf_url":null,"source":{"id":"https://openalex.org/S144140688","display_name":"Epilepsy Research","issn_l":"0920-1211","issn":["0920-1211","1872-6844"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy Research","raw_type":"journal-article"},{"id":"pmid:12151112","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12151112","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307214","display_name":"Citizens United for Research in Epilepsy","ror":"https://ror.org/01awnfh35"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":91,"referenced_works":["https://openalex.org/W31012121","https://openalex.org/W125809592","https://openalex.org/W196026329","https://openalex.org/W260429138","https://openalex.org/W566223476","https://openalex.org/W1482293895","https://openalex.org/W1523564114","https://openalex.org/W1561389266","https://openalex.org/W1565381549","https://openalex.org/W1613517808","https://openalex.org/W1913636106","https://openalex.org/W1956099131","https://openalex.org/W1964220613","https://openalex.org/W1966224996","https://openalex.org/W1966718766","https://openalex.org/W1967913742","https://openalex.org/W1971175458","https://openalex.org/W1973017105","https://openalex.org/W1974809694","https://openalex.org/W1976515134","https://openalex.org/W1980710017","https://openalex.org/W1981475942","https://openalex.org/W1992190571","https://openalex.org/W1998249177","https://openalex.org/W2002377344","https://openalex.org/W2002800880","https://openalex.org/W2003829544","https://openalex.org/W2005359439","https://openalex.org/W2007191703","https://openalex.org/W2008283166","https://openalex.org/W2009709934","https://openalex.org/W2012015292","https://openalex.org/W2014182056","https://openalex.org/W2016367349","https://openalex.org/W2018648309","https://openalex.org/W2019047657","https://openalex.org/W2021759214","https://openalex.org/W2021858421","https://openalex.org/W2023544660","https://openalex.org/W2030775506","https://openalex.org/W2031974372","https://openalex.org/W2042511069","https://openalex.org/W2044794051","https://openalex.org/W2045895751","https://openalex.org/W2046826638","https://openalex.org/W2047744286","https://openalex.org/W2047884170","https://openalex.org/W2050163545","https://openalex.org/W2050231500","https://openalex.org/W2050919987","https://openalex.org/W2051201583","https://openalex.org/W2055378886","https://openalex.org/W2056134297","https://openalex.org/W2057552859","https://openalex.org/W2060441889","https://openalex.org/W2061928059","https://openalex.org/W2063229517","https://openalex.org/W2067063194","https://openalex.org/W2069448135","https://openalex.org/W2071025146","https://openalex.org/W2079473624","https://openalex.org/W2081050155","https://openalex.org/W2082427007","https://openalex.org/W2082765500","https://openalex.org/W2082769957","https://openalex.org/W2082770075","https://openalex.org/W2086752457","https://openalex.org/W2086954644","https://openalex.org/W2108379135","https://openalex.org/W2120032663","https://openalex.org/W2121860375","https://openalex.org/W2124531204","https://openalex.org/W2130853198","https://openalex.org/W2141474963","https://openalex.org/W2145567354","https://openalex.org/W2146329326","https://openalex.org/W2147926788","https://openalex.org/W2148776940","https://openalex.org/W2153825927","https://openalex.org/W2166543123","https://openalex.org/W2317495993","https://openalex.org/W2407377771","https://openalex.org/W2410142354","https://openalex.org/W2412945974","https://openalex.org/W2492672166","https://openalex.org/W2504478589","https://openalex.org/W2728974037","https://openalex.org/W2768985409","https://openalex.org/W4233722803","https://openalex.org/W6723464852","https://openalex.org/W6745677321"],"related_works":["https://openalex.org/W2044989922","https://openalex.org/W2154436525","https://openalex.org/W1968212169","https://openalex.org/W621120138","https://openalex.org/W1970117905","https://openalex.org/W2559901472","https://openalex.org/W2118583212","https://openalex.org/W2524801494","https://openalex.org/W2111168462","https://openalex.org/W2506472380"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}