{"id":"https://openalex.org/W1990924057","doi":"https://doi.org/10.1046/j.1365-2605.2003.00391.x","title":"Comparison of sibling oocyte outcomes after intracytoplasmic sperm injection and in vitro fertilization in severe teratozoospermic patients in the first cycle","display_name":"Comparison of sibling oocyte outcomes after intracytoplasmic sperm injection and in vitro fertilization in severe teratozoospermic patients in the first cycle","publication_year":2003,"publication_date":"2003-01-10","ids":{"openalex":"https://openalex.org/W1990924057","doi":"https://doi.org/10.1046/j.1365-2605.2003.00391.x","mag":"1990924057","pmid":"https://pubmed.ncbi.nlm.nih.gov/12534939"},"language":"en","primary_location":{"id":"doi:10.1046/j.1365-2605.2003.00391.x","doi":"https://doi.org/10.1046/j.1365-2605.2003.00391.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1365-2605.2003.00391.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1365-2605.2003.00391.x","source":{"id":"https://openalex.org/S4394735506","display_name":"International Journal of Andrology","issn_l":"0105-6263","issn":["0105-6263","1365-2605"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Andrology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1365-2605.2003.00391.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070868630","display_name":"Paul E. Kihaile","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154840374","display_name":"Muhimbili University of Health and Allied Sciences","ror":"https://ror.org/027pr6c67","country_code":"TZ","type":"education","lineage":["https://openalex.org/I154840374"]},{"id":"https://openalex.org/I4405257666","display_name":"Omuta City Hospital","ror":"https://ror.org/05j05sz90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257666"]}],"countries":["JP","TZ"],"is_corresponding":true,"raw_author_name":"Paul E. Kihaile","raw_affiliation_strings":["Oita Medical University, Oita City, Japan, St Luke IVF Center, Oita City, Japan. kihaile@oita-med.ac.jp","Muhimbili University College of Health Science, Dar Es Salaam, Tanzania","Oita Medical University, Oita City, Japan,","St Luke IVF Center, Oita City, Japan, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oita Medical University, Oita City, Japan, St Luke IVF Center, Oita City, Japan. kihaile@oita-med.ac.jp","institution_ids":[]},{"raw_affiliation_string":"Muhimbili University College of Health Science, Dar Es Salaam, Tanzania","institution_ids":["https://openalex.org/I154840374"]},{"raw_affiliation_string":"Oita Medical University, Oita City, Japan,","institution_ids":["https://openalex.org/I4405257666"]},{"raw_affiliation_string":"St Luke IVF Center, Oita City, Japan, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066418156","display_name":"Junichi Misumi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Junichi Misumi","raw_affiliation_strings":["St Luke IVF Center, Oita City, Japan, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Luke IVF Center, Oita City, Japan, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061730646","display_name":"Keiko Hirotsuru","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Keiko Hirotsuru","raw_affiliation_strings":["St Luke IVF Center, Oita City, Japan, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Luke IVF Center, Oita City, Japan, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056684171","display_name":"Yoko Kumasako","orcid":"https://orcid.org/0000-0002-4814-7963","observed_orcids":["https://orcid.org/0000-0002-4814-7963"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yoko Kumasako","raw_affiliation_strings":["St Luke IVF Center, Oita City, Japan, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Luke IVF Center, Oita City, Japan, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063051633","display_name":"Ramzy E. Kisanga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154840374","display_name":"Muhimbili University of Health and Allied Sciences","ror":"https://ror.org/027pr6c67","country_code":"TZ","type":"education","lineage":["https://openalex.org/I154840374"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Ramzy E. Kisanga","raw_affiliation_strings":["Muhimbili University College of Health Science, Dar Es Salaam, Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Muhimbili University College of Health Science, Dar Es Salaam, Tanzania","institution_ids":["https://openalex.org/I154840374"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075561413","display_name":"Takafumi Utsunomiya","orcid":"https://orcid.org/0000-0003-2691-5519","observed_orcids":["https://orcid.org/0000-0003-2691-5519"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Takafumi Utsunomiya","raw_affiliation_strings":["St Luke IVF Center, Oita City, Japan, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Luke IVF Center, Oita City, Japan, and","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5070868630"],"corresponding_institution_ids":["https://openalex.org/I154840374","https://openalex.org/I4405257666"],"apc_list":null,"apc_paid":null,"fwci":0.432,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.60522829,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"26","issue":"1","first_page":"57","last_page":"62"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.08829999715089798,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.03550000116229057,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intracytoplasmic-sperm-injection","display_name":"intracytoplasmic sperm injection","score":0.9909999966621399},{"id":"https://openalex.org/keywords/in-vitro-fertilization","display_name":"in vitro fertilization","score":0.9929999709129333},{"id":"https://openalex.org/keywords/sibling-oocytes","display_name":"sibling oocytes","score":0.8410000205039978},{"id":"https://openalex.org/keywords/fertilization-rate","display_name":"fertilization rate","score":0.902999997138977},{"id":"https://openalex.org/keywords/fertilization-failure","display_name":"fertilization failure","score":0.9660000205039978},{"id":"https://openalex.org/keywords/embryonic-development","display_name":"embryonic development","score":0.9049999713897705},{"id":"https://openalex.org/keywords/blastocyst-development","display_name":"blastocyst development","score":0.9810000061988831},{"id":"https://openalex.org/keywords/embryo-transfer","display_name":"embryo transfer","score":0.6650000214576721},{"id":"https://openalex.org/keywords/pregnancy-rate","display_name":"pregnancy rate","score":0.574999988079071},{"id":"https://openalex.org/keywords/male-infertility","display_name":"male infertility","score":0.6729999780654907}],"concepts":[{"id":"https://openalex.org/C2778278907","wikidata":"https://www.wikidata.org/wiki/Q28700","display_name":"Intracytoplasmic sperm injection","level":4,"score":0.9169367551803589},{"id":"https://openalex.org/C512716672","wikidata":"https://www.wikidata.org/wiki/Q200117","display_name":"In vitro fertilisation","level":3,"score":0.8214264512062073},{"id":"https://openalex.org/C2776690073","wikidata":"https://www.wikidata.org/wiki/Q3246226","display_name":"Oocyte","level":3,"score":0.7278103828430176},{"id":"https://openalex.org/C88972607","wikidata":"https://www.wikidata.org/wiki/Q2666904","display_name":"Human fertilization","level":2,"score":0.6800339818000793},{"id":"https://openalex.org/C2776194465","wikidata":"https://www.wikidata.org/wiki/Q31184","display_name":"Sibling","level":2,"score":0.6564317941665649},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.6014060974121094},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3988454043865204},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34919023513793945},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.346442848443985},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1735357642173767},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.16735562682151794},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.1481802761554718},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.12552255392074585},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.05683514475822449}],"mesh":[{"descriptor_ui":"D001757","descriptor_name":"Blastomeres","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003593","descriptor_name":"Cytoplasm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005307","descriptor_name":"Fertilization in Vitro","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008845","descriptor_name":"Microinjections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009845","descriptor_name":"Oligospermia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1046/j.1365-2605.2003.00391.x","doi":"https://doi.org/10.1046/j.1365-2605.2003.00391.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1365-2605.2003.00391.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1365-2605.2003.00391.x","source":{"id":"https://openalex.org/S4394735506","display_name":"International Journal of Andrology","issn_l":"0105-6263","issn":["0105-6263","1365-2605"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Andrology","raw_type":"journal-article"},{"id":"pmid:12534939","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12534939","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of andrology","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1046/j.1365-2605.2003.00391.x","doi":"https://doi.org/10.1046/j.1365-2605.2003.00391.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1365-2605.2003.00391.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1365-2605.2003.00391.x","source":{"id":"https://openalex.org/S4394735506","display_name":"International Journal of Andrology","issn_l":"0105-6263","issn":["0105-6263","1365-2605"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Andrology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1990924057.pdf","grobid_xml":"https://content.openalex.org/works/W1990924057.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1966560868","https://openalex.org/W1967119909","https://openalex.org/W1986902208","https://openalex.org/W1992112951","https://openalex.org/W2003562671","https://openalex.org/W2013055589","https://openalex.org/W2023711110","https://openalex.org/W2030055959","https://openalex.org/W2032430446","https://openalex.org/W2043178143","https://openalex.org/W2055511320","https://openalex.org/W2063337177","https://openalex.org/W2070549645","https://openalex.org/W2090044308","https://openalex.org/W2095930579","https://openalex.org/W2096869522","https://openalex.org/W2100619372","https://openalex.org/W2101972543","https://openalex.org/W2111943906","https://openalex.org/W2118068788","https://openalex.org/W2121997289","https://openalex.org/W2125539183","https://openalex.org/W2126012794","https://openalex.org/W2126563053","https://openalex.org/W2141106947","https://openalex.org/W2142499540","https://openalex.org/W2146799584","https://openalex.org/W2147452407","https://openalex.org/W2159936712","https://openalex.org/W2162283601","https://openalex.org/W2168769529","https://openalex.org/W2177272367","https://openalex.org/W2283892449","https://openalex.org/W2304418195","https://openalex.org/W2318928538","https://openalex.org/W2344638721","https://openalex.org/W2402511601","https://openalex.org/W2407399611","https://openalex.org/W2407609662","https://openalex.org/W4387989831"],"related_works":["https://openalex.org/W1500266564","https://openalex.org/W1986902208","https://openalex.org/W2349582463","https://openalex.org/W2040191348","https://openalex.org/W2980400233","https://openalex.org/W7027169819","https://openalex.org/W2151487505","https://openalex.org/W2273682203","https://openalex.org/W2355726884","https://openalex.org/W2159936712"],"abstract_inverted_index":{"To":[0],"follow":[1],"up":[2,218],"the":[3,22,59,63,75,80,91,99,104,140,186,223],"outcome":[4],"of":[5,25,36,106,193,213],"sibling":[6,38,178],"oocytes":[7,41,179],"subjected":[8],"to":[9,180,219],"both":[10,181],"conventional":[11],"in":[12,21,43,74,79,90,98,153,166,176,185,206],"vitro":[13],"fertilization":[14,69,87,195,204],"(IVF)":[15],"and":[16,55,58,86,114,127,133,183],"intracytoplasmic":[17],"sperm":[18,31],"injection":[19],"(ICSI)":[20],"first":[23,187],"cycles":[24,45,192],"severe":[26,170],"teratozoospermic":[27],"patients":[28],"with":[29,168,231,243],"normal":[30],"morphology":[32],"(NSM)<or=4%,":[33],"a":[34,145,148,174],"total":[35,194],"1193":[37],"metaphase":[39],"II":[40],"(MII)":[42],"85":[44],"were":[46,66,197,222],"randomly":[47],"allocated":[48],"into":[49],"two":[50,64,141],"groups:":[51],"588":[52],"underwent":[53],"IVF":[54,81,100,182,209],"605":[56],"ICSI":[57,76,92,184,207,227],"embryo":[60,107,116,156,238],"outcomes":[61],"between":[62,139],"groups":[65,77],"compared.":[67],"The":[68],"rate":[70,89,151],"was":[71,95,144,173,240],"significantly":[72,138],"higher":[73,203],"than":[78,97,208],"group":[82,93,101],"(p":[83],"<":[84],"0.05)":[85],"failure":[88,196],"(2.3%)":[94],"lower":[96],"(28.2%).":[102],"Subsequently,":[103],"rates":[105,205,212],"arrest":[108],"as":[109,111,233],"well":[110],"grade":[112],"1":[113],"2":[115],"formation":[117,129],"before":[118],"day":[119,125,235],"3,":[120,236],">or=6":[121,216],"cell":[122],"embryos":[123],"on":[124,130],"3":[126],"blastocyst":[128,220],"days":[131],"5":[132],"6,":[134],"did":[135],"not":[136],"differ":[137],"groups.":[142],"There":[143],"trend":[146],"towards":[147],"high":[149],"pregnancy":[150],"cycle":[152,188],"mixed":[154],"ICSI/IVF":[155],"transfer":[157],"(ET)":[158],"(49.1%).":[159],"In":[160],"conclusion,":[161],"this":[162],"study":[163],"showed":[164],"that":[165,226],"couples":[167],"only":[169],"teratozoospermia,":[171],"there":[172],"benefit":[175],"subjecting":[177],"because":[189],"24":[190],"(28.2%)":[191],"avoided.":[198],"Furthermore,":[199],"despite":[200],"initially":[201],"significant":[202],"oocytes,":[210],"subsequent":[211],"development":[214,239],"from":[215],"cells":[217],"stage":[221],"same":[224],"suggesting":[225],"should":[228],"be":[229],"used":[230],"caution,":[232],"after":[234],"ICSI-derived":[237],"compromised":[241],"compared":[242],"IVF.":[244]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}