{"id":"https://openalex.org/W1990869971","doi":"https://doi.org/10.1016/j.biomaterials.2008.02.004","title":"Polyurethane with tethered copper(II)\u2013cyclen complex: Preparation, characterization and catalytic generation of nitric oxide from S-nitrosothiols","display_name":"Polyurethane with tethered copper(II)\u2013cyclen complex: Preparation, characterization and catalytic generation of nitric oxide from S-nitrosothiols","publication_year":2008,"publication_date":"2008-03-12","ids":{"openalex":"https://openalex.org/W1990869971","doi":"https://doi.org/10.1016/j.biomaterials.2008.02.004","mag":"1990869971","pmid":"https://pubmed.ncbi.nlm.nih.gov/18314189","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2408722"},"language":"en","primary_location":{"id":"doi:10.1016/j.biomaterials.2008.02.004","doi":"https://doi.org/10.1016/j.biomaterials.2008.02.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2008.02.004","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC2408722","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104050708","display_name":"Sangyeul Hwang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sangyeul Hwang","raw_affiliation_strings":["Department of Chemistry, The University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109-1055, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, The University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109-1055, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042520154","display_name":"Mark E. Meyerhoff","orcid":"https://orcid.org/0000-0002-7841-281X","observed_orcids":["https://orcid.org/0000-0002-7841-281X"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark E. Meyerhoff","raw_affiliation_strings":["Department of Chemistry, The University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109-1055, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, The University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109-1055, USA","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5042520154"],"corresponding_institution_ids":["https://openalex.org/I27837315"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":null,"fwci":2.254,"has_fulltext":false,"cited_by_count":83,"citation_normalized_percentile":{"value":0.85369936,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"29","issue":"16","first_page":"2443","last_page":"2452"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.635699987411499,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.635699987411499,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.14069999754428864,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10660","display_name":"Conducting polymers and applications","score":0.03620000183582306,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polyurethane","display_name":"polyurethane","score":0.8970000147819519},{"id":"https://openalex.org/keywords/nitric-oxide-production","display_name":"nitric oxide production","score":0.9079999923706055},{"id":"https://openalex.org/keywords/s-nitrosothiols","display_name":"S-nitrosothiols","score":0.9950000047683716},{"id":"https://openalex.org/keywords/s-nitrosoglutathione","display_name":"S-nitrosoglutathione","score":0.9929999709129333},{"id":"https://openalex.org/keywords/s-nitrosocysteine","display_name":"S-nitrosocysteine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/thiol-reducing-agents","display_name":"thiol reducing agents","score":0.7260000109672546},{"id":"https://openalex.org/keywords/chemiluminescence","display_name":"chemiluminescence","score":0.6510000228881836},{"id":"https://openalex.org/keywords/hemocompatibility","display_name":"hemocompatibility","score":0.8140000104904175},{"id":"https://openalex.org/keywords/medical-device-coatings","display_name":"medical device coatings","score":0.8479999899864197}],"concepts":[{"id":"https://openalex.org/C2777459166","wikidata":"https://www.wikidata.org/wiki/Q416407","display_name":"Cyclen","level":2,"score":0.8176775574684143},{"id":"https://openalex.org/C2779578285","wikidata":"https://www.wikidata.org/wiki/Q146322","display_name":"Polyurethane","level":2,"score":0.7957339286804199},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.575446605682373},{"id":"https://openalex.org/C2781448156","wikidata":"https://www.wikidata.org/wiki/Q1570182","display_name":"Coating","level":2,"score":0.5737344026565552},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.5706220269203186},{"id":"https://openalex.org/C2779201268","wikidata":"https://www.wikidata.org/wiki/Q186474","display_name":"Cysteine","level":3,"score":0.5650343894958496},{"id":"https://openalex.org/C2781324293","wikidata":"https://www.wikidata.org/wiki/Q220410","display_name":"Thiol","level":2,"score":0.5286477208137512},{"id":"https://openalex.org/C544778455","wikidata":"https://www.wikidata.org/wiki/Q753","display_name":"Copper","level":2,"score":0.5097135901451111},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.43454331159591675},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.4323226809501648},{"id":"https://openalex.org/C180577832","wikidata":"https://www.wikidata.org/wiki/Q127920","display_name":"Covalent bond","level":2,"score":0.4321698844432831},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.2856918275356293},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.26242151856422424},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.24739283323287964},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.08770692348480225},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000080027","descriptor_name":"Cyclams","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D002384","descriptor_name":"Catalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003300","descriptor_name":"Copper","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006571","descriptor_name":"Heterocyclic Compounds","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011140","descriptor_name":"Polyurethanes","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026403","descriptor_name":"S-Nitrosothiols","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.biomaterials.2008.02.004","doi":"https://doi.org/10.1016/j.biomaterials.2008.02.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2008.02.004","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},{"id":"pmid:18314189","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18314189","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:1454394","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC2408722","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2408722","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2408722","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1454394","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC2408722","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3660285987","display_name":null,"funder_award_id":"W81XWH-05-1-0602","funder_id":"https://openalex.org/F4320332447","funder_display_name":"U.S. Army"},{"id":"https://openalex.org/G4594127802","display_name":"Thromboresistant Polymers Via Catalytic Generation of NO","funder_award_id":"R01EB004527","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G7149412196","display_name":"Biocompatible Chemical Sensors Via Nitric Oxide Release/Generation","funder_award_id":"R01EB000783","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"}],"funders":[{"id":"https://openalex.org/F4320309454","display_name":"Lubrizol","ror":"https://ror.org/02pq7w335"},{"id":"https://openalex.org/F4320309652","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332447","display_name":"U.S. Army","ror":"https://ror.org/00afsp483"},{"id":"https://openalex.org/F4320332682","display_name":"Medical School, University of Michigan","ror":"https://ror.org/00jmfr291"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W189916423","https://openalex.org/W207776694","https://openalex.org/W1481997706","https://openalex.org/W1502565234","https://openalex.org/W1872156566","https://openalex.org/W1918557825","https://openalex.org/W1967225427","https://openalex.org/W1969484914","https://openalex.org/W1973873605","https://openalex.org/W1978953095","https://openalex.org/W1985284129","https://openalex.org/W1985864082","https://openalex.org/W1986227359","https://openalex.org/W1990268295","https://openalex.org/W1992404965","https://openalex.org/W1997360994","https://openalex.org/W1999511683","https://openalex.org/W2000880983","https://openalex.org/W2004649932","https://openalex.org/W2005281763","https://openalex.org/W2006883085","https://openalex.org/W2016811924","https://openalex.org/W2022143873","https://openalex.org/W2023803596","https://openalex.org/W2026021985","https://openalex.org/W2030038351","https://openalex.org/W2040852689","https://openalex.org/W2043033553","https://openalex.org/W2046001203","https://openalex.org/W2050651028","https://openalex.org/W2057764953","https://openalex.org/W2060119002","https://openalex.org/W2060707726","https://openalex.org/W2061142495","https://openalex.org/W2061950890","https://openalex.org/W2065931676","https://openalex.org/W2076416805","https://openalex.org/W2078406689","https://openalex.org/W2084569746","https://openalex.org/W2087614924","https://openalex.org/W2090431966","https://openalex.org/W2092175186","https://openalex.org/W2101288009","https://openalex.org/W2104380573","https://openalex.org/W2131365805","https://openalex.org/W2131648977","https://openalex.org/W2154962376","https://openalex.org/W2157869016","https://openalex.org/W2160935854","https://openalex.org/W2164428662","https://openalex.org/W2232894234","https://openalex.org/W2951769065","https://openalex.org/W3024318743","https://openalex.org/W3138138101","https://openalex.org/W4238867104"],"related_works":["https://openalex.org/W2160963552","https://openalex.org/W1970653801","https://openalex.org/W113602015","https://openalex.org/W2729105215","https://openalex.org/W2035260587","https://openalex.org/W3017054980","https://openalex.org/W2160935854","https://openalex.org/W2751703420","https://openalex.org/W2037640551","https://openalex.org/W2921068510"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}