{"id":"https://openalex.org/W1990798640","doi":"https://doi.org/10.1016/j.jpainsymman.2007.10.005","title":"Intravenous Ibandronate Rapidly Reduces Pain, Neurochemical Indices of Central Sensitization, Tumor Burden, and Skeletal Destruction in a Mouse Model of Bone Cancer","display_name":"Intravenous Ibandronate Rapidly Reduces Pain, Neurochemical Indices of Central Sensitization, Tumor Burden, and Skeletal Destruction in a Mouse Model of Bone Cancer","publication_year":2008,"publication_date":"2008-04-15","ids":{"openalex":"https://openalex.org/W1990798640","doi":"https://doi.org/10.1016/j.jpainsymman.2007.10.005","mag":"1990798640","pmid":"https://pubmed.ncbi.nlm.nih.gov/18411018","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2638081"},"language":"en","primary_location":{"id":"doi:10.1016/j.jpainsymman.2007.10.005","doi":"https://doi.org/10.1016/j.jpainsymman.2007.10.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpainsymman.2007.10.005","pdf_url":"http://www.jpsmjournal.com/article/S0885392408001012/pdf","source":{"id":"https://openalex.org/S135898356","display_name":"Journal of Pain and Symptom Management","issn_l":"0885-3924","issn":["0885-3924","1873-6513"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pain and Symptom Management","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jpsmjournal.com/article/S0885392408001012/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063032024","display_name":"Kyle Gregory Halvorson","orcid":"https://orcid.org/0000-0002-4405-3900","observed_orcids":["https://orcid.org/0000-0002-4405-3900"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyle G. Halvorson","raw_affiliation_strings":["Neurosystems Center and Department of Diagnostic and Biological Sciences, University of Minnesota, Minneapolis, Minnesota, USA","Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurosystems Center and Department of Diagnostic and Biological Sciences, University of Minnesota, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111888855","display_name":"Molly A. Sevcik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Molly A. Sevcik","raw_affiliation_strings":["Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069547559","display_name":"Joseph R. Ghilardi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I4210117246","display_name":"Minneapolis VA Health Care System","ror":"https://ror.org/02ry60714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924"]},{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph R. Ghilardi","raw_affiliation_strings":["Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center , University of Minnesota (K","and Research Service ,","Research Service VA Medical Center, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center , University of Minnesota (K","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"and Research Service ,","institution_ids":[]},{"raw_affiliation_string":"Research Service VA Medical Center, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I4210117246","https://openalex.org/I4210140408"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lucy J. Sullivan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lucy J. Sullivan","raw_affiliation_strings":["Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005344125","display_name":"Nathan J. Koewler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nathan J. Koewler","raw_affiliation_strings":["Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center , University of Minnesota (K","VA Medical Center (J.R. G., P.W.M.) , Minneapolis , Minnesota , USA;","Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center , University of Minnesota (K","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"VA Medical Center (J.R. G., P.W.M.) , Minneapolis , Minnesota , USA;","institution_ids":["https://openalex.org/I4210140408"]},{"raw_affiliation_string":"Neurosystems Center and Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, and Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021205472","display_name":"Frieder Bauss","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Frieder Bauss","raw_affiliation_strings":["Roche Diagnostics GmbH, Pharma Research Penzberg, Penzberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roche Diagnostics GmbH, Pharma Research Penzberg, Penzberg, Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113547658","display_name":"P.W. Mantyh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]},{"id":"https://openalex.org/I4210117246","display_name":"Minneapolis VA Health Care System","ror":"https://ror.org/02ry60714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924"]},{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Patrick\u00a0W. Mantyh","raw_affiliation_strings":["Department of Pharmacology, University of Arizona College of Medicine, Tucson, Arizona, USA","Research Service, VA Medical Center, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Arizona College of Medicine, Tucson, Arizona, USA","institution_ids":["https://openalex.org/I138006243"]},{"raw_affiliation_string":"Research Service, VA Medical Center, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I4210117246","https://openalex.org/I4210140408"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5113547658"],"corresponding_institution_ids":["https://openalex.org/I138006243","https://openalex.org/I4210117246","https://openalex.org/I4210140408"],"apc_list":{"value":4760,"currency":"USD","value_usd":4760},"apc_paid":null,"fwci":0.3683,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.6622759,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"36","issue":"3","first_page":"289","last_page":"303"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":0.6582000255584717,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":0.6582000255584717,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.22200000286102295,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.09769999980926514,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ibandronate","display_name":"ibandronate","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bisphosphonates","display_name":"bisphosphonates","score":0.9520000219345093},{"id":"https://openalex.org/keywords/bone-cancer-pain","display_name":"bone cancer pain","score":0.9269999861717224},{"id":"https://openalex.org/keywords/bone-metastases","display_name":"bone metastasis","score":0.6639999747276306},{"id":"https://openalex.org/keywords/central-sensitization","display_name":"central sensitization","score":0.8569999933242798},{"id":"https://openalex.org/keywords/tumor-induced-bone-destruction","display_name":"tumor-induced bone destruction","score":0.8090000152587891},{"id":"https://openalex.org/keywords/non-opioid-analgesia","display_name":"non-opioid analgesia","score":0.7889999747276306},{"id":"https://openalex.org/keywords/intravenous-administration","display_name":"intravenous administration","score":0.6959999799728394},{"id":"https://openalex.org/keywords/neurochemical-markers","display_name":"neurochemical markers","score":0.6990000009536743},{"id":"https://openalex.org/keywords/tumor-burden","display_name":"tumor burden","score":0.6389999985694885},{"id":"https://openalex.org/keywords/chronic-cancer-pain","display_name":"chronic cancer pain","score":0.656000018119812}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9449262619018555},{"id":"https://openalex.org/C2776035513","wikidata":"https://www.wikidata.org/wiki/Q1328805","display_name":"Bone cancer","level":3,"score":0.762887716293335},{"id":"https://openalex.org/C2776139714","wikidata":"https://www.wikidata.org/wiki/Q3480107","display_name":"Bone pain","level":2,"score":0.6362928748130798},{"id":"https://openalex.org/C25876315","wikidata":"https://www.wikidata.org/wiki/Q15197465","display_name":"Neurochemical","level":2,"score":0.6318791508674622},{"id":"https://openalex.org/C2777251235","wikidata":"https://www.wikidata.org/wiki/Q412205","display_name":"Bisphosphonate","level":3,"score":0.5979142189025879},{"id":"https://openalex.org/C2776217527","wikidata":"https://www.wikidata.org/wiki/Q944828","display_name":"Sensitization","level":2,"score":0.5795612335205078},{"id":"https://openalex.org/C2778904085","wikidata":"https://www.wikidata.org/wiki/Q3712728","display_name":"Cancer pain","level":3,"score":0.5727372169494629},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5429529547691345},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5009140968322754},{"id":"https://openalex.org/C673006","wikidata":"https://www.wikidata.org/wiki/Q4941581","display_name":"Bone resorption","level":2,"score":0.41376766562461853},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3251780867576599},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31436681747436523},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.29809653759002686},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.11041736602783203}],"mesh":[{"descriptor_ui":"D000077557","descriptor_name":"Ibandronic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004164","descriptor_name":"Diphosphonates","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007275","descriptor_name":"Injections, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008809","descriptor_name":"Mice, Inbred C3H","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010014","descriptor_name":"Osteolysis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010014","descriptor_name":"Osteolysis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010014","descriptor_name":"Osteolysis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D010014","descriptor_name":"Osteolysis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012516","descriptor_name":"Osteosarcoma","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012516","descriptor_name":"Osteosarcoma","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012516","descriptor_name":"Osteosarcoma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012516","descriptor_name":"Osteosarcoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050071","descriptor_name":"Bone Density Conservation Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jpainsymman.2007.10.005","doi":"https://doi.org/10.1016/j.jpainsymman.2007.10.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpainsymman.2007.10.005","pdf_url":"http://www.jpsmjournal.com/article/S0885392408001012/pdf","source":{"id":"https://openalex.org/S135898356","display_name":"Journal of Pain and Symptom Management","issn_l":"0885-3924","issn":["0885-3924","1873-6513"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pain and Symptom Management","raw_type":"journal-article"},{"id":"pmid:18411018","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18411018","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pain and symptom management","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:1502236","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2638081","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2638081","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2638081","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Pain Symptom Manage","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.jpainsymman.2007.10.005","doi":"https://doi.org/10.1016/j.jpainsymman.2007.10.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpainsymman.2007.10.005","pdf_url":"http://www.jpsmjournal.com/article/S0885392408001012/pdf","source":{"id":"https://openalex.org/S135898356","display_name":"Journal of Pain and Symptom Management","issn_l":"0885-3924","issn":["0885-3924","1873-6513"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pain and Symptom Management","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3261739245","display_name":null,"funder_award_id":"NS23970","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3540671580","display_name":"Peripheral Nociceptors in Persistent Pain","funder_award_id":"R01NS023970","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G5162347089","display_name":"Cancer Pain and Breast Tumor Metastasis to Bone","funder_award_id":"R01NS048021","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G8258755420","display_name":"PERIPHERAL NOCICEPTORS IN PERSISTENT PAIN","funder_award_id":"R37NS023970","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000302653","display_name":null,"funder_award_id":"NS23970","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320309432","display_name":"F. Hoffmann-La Roche","ror":"https://ror.org/00by1q217"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1990798640.pdf","grobid_xml":"https://content.openalex.org/works/W1990798640.grobid-xml"},"referenced_works_count":78,"referenced_works":["https://openalex.org/W564852975","https://openalex.org/W1511198581","https://openalex.org/W1577265851","https://openalex.org/W1720952724","https://openalex.org/W1867790738","https://openalex.org/W1867981554","https://openalex.org/W1896223819","https://openalex.org/W1938796902","https://openalex.org/W1944967894","https://openalex.org/W1963668674","https://openalex.org/W1965511198","https://openalex.org/W1967875617","https://openalex.org/W1972227666","https://openalex.org/W1972611111","https://openalex.org/W1974642350","https://openalex.org/W1974903174","https://openalex.org/W1977203209","https://openalex.org/W1979253120","https://openalex.org/W1994414479","https://openalex.org/W1999085114","https://openalex.org/W2000144084","https://openalex.org/W2001026574","https://openalex.org/W2005039015","https://openalex.org/W2005865069","https://openalex.org/W2006825597","https://openalex.org/W2009067227","https://openalex.org/W2011195852","https://openalex.org/W2011398881","https://openalex.org/W2012291531","https://openalex.org/W2012553144","https://openalex.org/W2013001448","https://openalex.org/W2013255360","https://openalex.org/W2020558434","https://openalex.org/W2025605415","https://openalex.org/W2028991114","https://openalex.org/W2029466905","https://openalex.org/W2030266268","https://openalex.org/W2033421804","https://openalex.org/W2035190861","https://openalex.org/W2036545264","https://openalex.org/W2051337621","https://openalex.org/W2053916112","https://openalex.org/W2054012939","https://openalex.org/W2055870169","https://openalex.org/W2060314283","https://openalex.org/W2061235833","https://openalex.org/W2061539449","https://openalex.org/W2066362290","https://openalex.org/W2067177940","https://openalex.org/W2074781113","https://openalex.org/W2083499857","https://openalex.org/W2089158347","https://openalex.org/W2089272876","https://openalex.org/W2093164779","https://openalex.org/W2094127804","https://openalex.org/W2102482103","https://openalex.org/W2106142458","https://openalex.org/W2107705149","https://openalex.org/W2115377499","https://openalex.org/W2115745004","https://openalex.org/W2127461273","https://openalex.org/W2129296139","https://openalex.org/W2134664830","https://openalex.org/W2135607542","https://openalex.org/W2137575981","https://openalex.org/W2142402689","https://openalex.org/W2144860907","https://openalex.org/W2168222534","https://openalex.org/W2169491449","https://openalex.org/W2193657784","https://openalex.org/W2413083042","https://openalex.org/W2586865716","https://openalex.org/W2992368079","https://openalex.org/W4253401993","https://openalex.org/W6640777412","https://openalex.org/W6675323744","https://openalex.org/W6679090616","https://openalex.org/W6684967989"],"related_works":["https://openalex.org/W2057827863","https://openalex.org/W2185472936","https://openalex.org/W2020558434","https://openalex.org/W2011398881","https://openalex.org/W1590649174","https://openalex.org/W2387091606","https://openalex.org/W2014729952","https://openalex.org/W2028582802","https://openalex.org/W2358596651","https://openalex.org/W2366657111"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
