{"id":"https://openalex.org/W1990699323","doi":"https://doi.org/10.1007/bf00685675","title":"Decreased resistance toN,N-dimethylated anthracyclines in multidrug-resistant Friend erythroleukemia cells","display_name":"Decreased resistance toN,N-dimethylated anthracyclines in multidrug-resistant Friend erythroleukemia cells","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W1990699323","doi":"https://doi.org/10.1007/bf00685675","mag":"1990699323","pmid":"https://pubmed.ncbi.nlm.nih.gov/8422694"},"language":"en","primary_location":{"id":"doi:10.1007/bf00685675","doi":"https://doi.org/10.1007/bf00685675","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00685675","pdf_url":null,"source":{"id":"https://openalex.org/S117498271","display_name":"Cancer Chemotherapy and Pharmacology","issn_l":"0344-5704","issn":["0344-5704","1432-0843"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Chemotherapy and Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109982467","display_name":"A. Schaefer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4923324","display_name":"Fraunhofer-Gesellschaft","ror":"https://ror.org/05hkkdn48","country_code":"DE","type":"government","lineage":["https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andr\ufffds Schaefer","raw_affiliation_strings":["Department of Toxicology, University of Hamburg Medical School, Germany","Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057936407","display_name":"Johannes Westendorf","orcid":"https://orcid.org/0000-0002-2895-1655","observed_orcids":["https://orcid.org/0000-0002-2895-1655"]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4923324","display_name":"Fraunhofer-Gesellschaft","ror":"https://ror.org/05hkkdn48","country_code":"DE","type":"government","lineage":["https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Johannes Westendorf","raw_affiliation_strings":["Department of Pharmacology, University of Hamburg Medical School, D-2000, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Grindelallee 117, D-2000, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, D-2000, Hamburg, Germany","Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, D-2000, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Grindelallee 117, D-2000, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, D-2000, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]},{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076438694","display_name":"Klaus R. Lingelbach","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4923324","display_name":"Fraunhofer-Gesellschaft","ror":"https://ror.org/05hkkdn48","country_code":"DE","type":"government","lineage":["https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Klaus Lingelbach","raw_affiliation_strings":["Department of Pharmacology, University of Hamburg Medical School, D-2000, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Grindelallee 117, D-2000, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, D-2000, Hamburg, Germany","Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, D-2000, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Grindelallee 117, D-2000, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, D-2000, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]},{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103576528","display_name":"Christian Andreas Schmidt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christian A. Schmidt","raw_affiliation_strings":["Laboratory of Immunibiochemistry, University Hospital Rudolf Virchow, D-1000, Berlin, Germany","Laboratory of Immunibiochemistry, University Hospital Rudolf Virchow, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunibiochemistry, University Hospital Rudolf Virchow, D-1000, Berlin, Germany","institution_ids":[]},{"raw_affiliation_string":"Laboratory of Immunibiochemistry, University Hospital Rudolf Virchow, Berlin, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042255894","display_name":"Doina-Lucia Mihalache","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4923324","display_name":"Fraunhofer-Gesellschaft","ror":"https://ror.org/05hkkdn48","country_code":"DE","type":"government","lineage":["https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Doina-Lucia Mihalache","raw_affiliation_strings":["Department of Pharmacology, University of Hamburg Medical School, D-2000, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Grindelallee 117, D-2000, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, D-2000, Hamburg, Germany","Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, D-2000, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Grindelallee 117, D-2000, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, D-2000, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]},{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010983747","display_name":"Andreas Reymann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4923324","display_name":"Fraunhofer-Gesellschaft","ror":"https://ror.org/05hkkdn48","country_code":"DE","type":"government","lineage":["https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andreas Reymann","raw_affiliation_strings":["Department of Pharmacology, University of Hamburg Medical School, D-2000, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Grindelallee 117, D-2000, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, D-2000, Hamburg, Germany","Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, D-2000, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Grindelallee 117, D-2000, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, D-2000, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]},{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091500719","display_name":"Hans Marquardt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4923324","display_name":"Fraunhofer-Gesellschaft","ror":"https://ror.org/05hkkdn48","country_code":"DE","type":"government","lineage":["https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hans Marquardt","raw_affiliation_strings":["Department of Pharmacology, University of Hamburg Medical School, D-2000, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Grindelallee 117, D-2000, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, D-2000, Hamburg, Germany","Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, D-2000, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Grindelallee 117, D-2000, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, D-2000, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]},{"raw_affiliation_string":"Department of Pharmacology, University of Hamburg Medical School, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Department of Toxicology, University of Hamburg Medical School, Hamburg 13, Germany","institution_ids":["https://openalex.org/I159176309"]},{"raw_affiliation_string":"Fraunhofer Institute of Toxicology and Molecular Biology, Hamburg, Germany","institution_ids":["https://openalex.org/I4923324"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":0.2129,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.55471442,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"31","issue":"4","first_page":"301","last_page":"307"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11845","display_name":"Cancer therapeutics and mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multidrug-resistance","display_name":"multidrug resistance","score":0.9509999752044678},{"id":"https://openalex.org/keywords/anthracyclines","display_name":"anthracyclines","score":0.8790000081062317},{"id":"https://openalex.org/keywords/doxorubicin-resistance","display_name":"doxorubicin resistance","score":0.9079999923706055},{"id":"https://openalex.org/keywords/daunorubicin","display_name":"daunorubicin","score":0.8429999947547913},{"id":"https://openalex.org/keywords/friend-erythroleukemia-cells","display_name":"Friend erythroleukemia cells","score":0.9229999780654907},{"id":"https://openalex.org/keywords/drug-efflux-pumps","display_name":"drug efflux pumps","score":0.8529999852180481},{"id":"https://openalex.org/keywords/verapamil","display_name":"verapamil","score":0.7110000252723694},{"id":"https://openalex.org/keywords/drug-accumulation","display_name":"drug accumulation","score":0.6489999890327454},{"id":"https://openalex.org/keywords/n-alkylation","display_name":"N-alkylation","score":0.7350000143051147}],"concepts":[{"id":"https://openalex.org/C2781021840","wikidata":"https://www.wikidata.org/wiki/Q411659","display_name":"Daunorubicin","level":3,"score":0.9643995761871338},{"id":"https://openalex.org/C2781303535","wikidata":"https://www.wikidata.org/wiki/Q18936","display_name":"Doxorubicin","level":3,"score":0.8690557479858398},{"id":"https://openalex.org/C2776802502","wikidata":"https://www.wikidata.org/wiki/Q417589","display_name":"Anthracycline","level":4,"score":0.6531170010566711},{"id":"https://openalex.org/C133936738","wikidata":"https://www.wikidata.org/wiki/Q643839","display_name":"Multiple drug resistance","level":3,"score":0.6495190858840942},{"id":"https://openalex.org/C200082930","wikidata":"https://www.wikidata.org/wiki/Q22327148","display_name":"Efflux","level":2,"score":0.6477444171905518},{"id":"https://openalex.org/C2778707650","wikidata":"https://www.wikidata.org/wiki/Q412902","display_name":"P-glycoprotein","level":4,"score":0.5134116411209106},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44935134053230286},{"id":"https://openalex.org/C2777022698","wikidata":"https://www.wikidata.org/wiki/Q410291","display_name":"Verapamil","level":3,"score":0.4293726086616516},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3868810832500458},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34142935276031494},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3233427405357361},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.3127816915512085},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.305753618478775},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.26583153009414673},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.22293215990066528},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17713943123817444},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1667868196964264},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.10408776998519897},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.060960620641708374},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000903","descriptor_name":"Antibiotics, Antineoplastic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004351","descriptor_name":"Drug Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004915","descriptor_name":"Leukemia, Erythroblastic, Acute","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D005622","descriptor_name":"Friend murine leukemia virus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D015152","descriptor_name":"Blotting, Northern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf00685675","doi":"https://doi.org/10.1007/bf00685675","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00685675","pdf_url":null,"source":{"id":"https://openalex.org/S117498271","display_name":"Cancer Chemotherapy and Pharmacology","issn_l":"0344-5704","issn":["0344-5704","1432-0843"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Chemotherapy and Pharmacology","raw_type":"journal-article"},{"id":"pmid:8422694","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8422694","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer chemotherapy and pharmacology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W1494133090","https://openalex.org/W1514525963","https://openalex.org/W1532410496","https://openalex.org/W1569205373","https://openalex.org/W1571521625","https://openalex.org/W1574598087","https://openalex.org/W1583339960","https://openalex.org/W1645460279","https://openalex.org/W1837265740","https://openalex.org/W1862646181","https://openalex.org/W1887213001","https://openalex.org/W1964595610","https://openalex.org/W1981012161","https://openalex.org/W1988667160","https://openalex.org/W1989012593","https://openalex.org/W1990062577","https://openalex.org/W1993209096","https://openalex.org/W1997241897","https://openalex.org/W2005408885","https://openalex.org/W2005448080","https://openalex.org/W2014669590","https://openalex.org/W2016254453","https://openalex.org/W2018652769","https://openalex.org/W2025603165","https://openalex.org/W2028458233","https://openalex.org/W2045853679","https://openalex.org/W2049683781","https://openalex.org/W2063879198","https://openalex.org/W2064177299","https://openalex.org/W2065444128","https://openalex.org/W2066943324","https://openalex.org/W2077077811","https://openalex.org/W2086101456","https://openalex.org/W2090497028","https://openalex.org/W2093554313","https://openalex.org/W2097878215","https://openalex.org/W2104733808","https://openalex.org/W2106162029","https://openalex.org/W2107615796","https://openalex.org/W2113851207","https://openalex.org/W2117398529","https://openalex.org/W2133602906","https://openalex.org/W2134812217","https://openalex.org/W2138691689","https://openalex.org/W2149535267","https://openalex.org/W2152029190","https://openalex.org/W2161087497","https://openalex.org/W2163282661","https://openalex.org/W2174476953","https://openalex.org/W2230711222","https://openalex.org/W2408993012","https://openalex.org/W2412310120","https://openalex.org/W2469826906","https://openalex.org/W2473122656","https://openalex.org/W2952121902","https://openalex.org/W4253385789"],"related_works":["https://openalex.org/W7027946395","https://openalex.org/W2398375649","https://openalex.org/W2006534624","https://openalex.org/W2037468006","https://openalex.org/W1995035622","https://openalex.org/W1981012161","https://openalex.org/W2443261140","https://openalex.org/W2979118999","https://openalex.org/W2419298103","https://openalex.org/W1494133090"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}