{"id":"https://openalex.org/W1990689337","doi":"https://doi.org/10.1148/radiology.204.3.9280272","title":"Invasive thymoma: treatment with postoperative radiation therapy.","display_name":"Invasive thymoma: treatment with postoperative radiation therapy.","publication_year":1997,"publication_date":"1997-09-01","ids":{"openalex":"https://openalex.org/W1990689337","doi":"https://doi.org/10.1148/radiology.204.3.9280272","mag":"1990689337","pmid":"https://pubmed.ncbi.nlm.nih.gov/9280272"},"language":"en","primary_location":{"id":"doi:10.1148/radiology.204.3.9280272","doi":"https://doi.org/10.1148/radiology.204.3.9280272","is_oa":false,"landing_page_url":"https://doi.org/10.1148/radiology.204.3.9280272","pdf_url":null,"source":{"id":"https://openalex.org/S50280174","display_name":"Radiology","issn_l":"0033-8419","issn":["0033-8419","1527-1315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315931","host_organization_name":"Radiological Society of North America","host_organization_lineage":["https://openalex.org/P4310315931"],"host_organization_lineage_names":["Radiological Society of North America"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066766230","display_name":"Detlev Latz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"D Latz","raw_affiliation_strings":["Department of Radiotherapy, University of Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiotherapy, University of Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086770411","display_name":"P. Schraube","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Schraube","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083350503","display_name":"Ulrich Oppitz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"U Oppitz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113732465","display_name":"C Kugler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Kugler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086106205","display_name":"Chris Manegold","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Manegold","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046756579","display_name":"Michael P. Flentje","orcid":"https://orcid.org/0000-0002-9463-4535","observed_orcids":["https://orcid.org/0000-0002-9463-4535"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Flentje","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5060443914","display_name":"Michael F. Wannenmacher","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M F Wannenmacher","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.5493,"has_fulltext":false,"cited_by_count":67,"citation_normalized_percentile":{"value":0.88233474,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"204","issue":"3","first_page":"859","last_page":"864"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11271","display_name":"Myasthenia Gravis and Thymoma","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11271","display_name":"Myasthenia Gravis and Thymoma","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11638","display_name":"Cardiac tumors and thrombi","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/invasive-thymoma","display_name":"invasive thymoma","score":0.9940000176429749},{"id":"https://openalex.org/keywords/thymic-carcinoma","display_name":"thymic carcinoma","score":1.0},{"id":"https://openalex.org/keywords/postoperative-radiotherapy","display_name":"postoperative radiotherapy","score":0.8759999871253967},{"id":"https://openalex.org/keywords/adjuvant-radiotherapy","display_name":"adjuvant radiotherapy","score":0.7770000100135803},{"id":"https://openalex.org/keywords/thymectomy","display_name":"thymectomy","score":0.6340000033378601},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.5889999866485596},{"id":"https://openalex.org/keywords/masaoka-stage","display_name":"Masaoka stage","score":0.7889999747276306},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.746999979019165},{"id":"https://openalex.org/keywords/local-control","display_name":"local control","score":0.871999979019165},{"id":"https://openalex.org/keywords/thoracic-radiotherapy","display_name":"thoracic radiotherapy","score":0.6000000238418579}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9593856334686279},{"id":"https://openalex.org/C2779159893","wikidata":"https://www.wikidata.org/wiki/Q1429863","display_name":"Thymoma","level":2,"score":0.8890984058380127},{"id":"https://openalex.org/C2776349617","wikidata":"https://www.wikidata.org/wiki/Q7799620","display_name":"Thymic carcinoma","level":3,"score":0.7024487257003784},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6942815780639648},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.6298642158508301},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.6074212193489075},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.536436915397644},{"id":"https://openalex.org/C2776283816","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Survival rate","level":2,"score":0.510709285736084},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.4578797221183777},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24253451824188232},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013945","descriptor_name":"Thymoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D013945","descriptor_name":"Thymoma","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D013945","descriptor_name":"Thymoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D013953","descriptor_name":"Thymus Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D013953","descriptor_name":"Thymus Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D013953","descriptor_name":"Thymus Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1148/radiology.204.3.9280272","doi":"https://doi.org/10.1148/radiology.204.3.9280272","is_oa":false,"landing_page_url":"https://doi.org/10.1148/radiology.204.3.9280272","pdf_url":null,"source":{"id":"https://openalex.org/S50280174","display_name":"Radiology","issn_l":"0033-8419","issn":["0033-8419","1527-1315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315931","host_organization_name":"Radiological Society of North America","host_organization_lineage":["https://openalex.org/P4310315931"],"host_organization_lineage_names":["Radiological Society of North America"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiology","raw_type":"journal-article"},{"id":"pmid:9280272","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9280272","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W155121692","https://openalex.org/W1973959930","https://openalex.org/W2066874194","https://openalex.org/W2104048219","https://openalex.org/W2148086522","https://openalex.org/W2034096683","https://openalex.org/W2158542993","https://openalex.org/W2328065948","https://openalex.org/W1996652471","https://openalex.org/W2070747210"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"assess":[2],"radiation":[3,150,176,216],"therapy":[4],"and":[5,13,59,79,114,121,128,133,136,156,175,182],"chemotherapy":[6,174,226],"in":[7,53,57,61,227],"the":[8,149,162,169,223,228],"treatment":[9,229],"of":[10,96,186,196,225,230],"invasive":[11,44,106],"thymoma":[12,45,107],"thymic":[14,38,90,180],"carcinoma.":[15],"MATERIALS":[16],"AND":[17],"METHODS:":[18],"In":[19],"1981-1995,":[20],"43":[21],"patients":[22,74,104,171,207],"received":[23,85,173],"irradiation":[24],"after":[25,203,217],"total":[26,64,194],"(n":[27,32,40,46],"=":[28,33,41,47,109,143],"23)":[29],"or":[30,43],"subtotal":[31],"20)":[34],"resection.":[35,205],"Tumors":[36],"were":[37,118],"carcinoma":[39,91,181],"10)":[42],"33).":[48],"Masaoka":[49],"stage":[50,77,82,124,131,139,211],"was":[51,67,152,164],"II":[52,212],"10":[54],"patients,":[55],"III":[56,78],"14,":[58],"IV":[60,140],"19.":[62],"Median":[63],"dose":[65],"applied":[66],"50":[68,101],"Gy":[69],"(range,":[70,189],"10-72":[71],"Gy).":[72],"Seventeen":[73],"(five":[75],"with":[76,81,89,100,105,208],"12":[80,187],"IV)":[83],"also":[84],"chemotherapy.":[86],"RESULTS:":[87],"Patients":[88],"had":[92,179],"a":[93,183],"median":[94,112,184],"survival":[95,113,116,185],"9.5":[97],"months,":[98],"compared":[99],"months":[102,120,127,135,188],"for":[103,123,130,138],"(P":[108,142],".008).":[110],"Patients'":[111],"5-year":[115],"rates":[117],"97":[119],"90%":[122],"II,":[125],"65":[126],"67%":[129],"III,":[132],"32.5":[134],"30%":[137],"tumors":[141],".024).":[144],"Overall":[145],"control":[146,159,200],"rate":[147,160],"within":[148,161],"field":[151],"81%":[153],"(35":[154],"patients)":[155],"overall":[157],"local":[158,199],"thorax":[163],"74%":[165],"(32":[166],"patients).":[167],"Of":[168],"17":[170],"who":[172],"therapy,":[177],"nine":[178],"1.4-23.0":[190],"months).":[191],"CONCLUSION:":[192],"With":[193],"doses":[195],"45-50":[197],"Gy,":[198],"is":[201],"achievable":[202],"radical":[204],"Whether":[206],"completely":[209],"resected":[210],"thymomas":[213],"should":[214],"receive":[215],"surgery":[218],"remains":[219],"uncertain,":[220],"as":[221],"does":[222],"role":[224],"thymoma.":[231]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}