{"id":"https://openalex.org/W1990679391","doi":"https://doi.org/10.1161/01.cir.55.1.195","title":"Increases in plasma oncotic pressure during acute cardiogenic pulmonary edema.","display_name":"Increases in plasma oncotic pressure during acute cardiogenic pulmonary edema.","publication_year":1977,"publication_date":"1977-01-01","ids":{"openalex":"https://openalex.org/W1990679391","doi":"https://doi.org/10.1161/01.cir.55.1.195","mag":"1990679391","pmid":"https://pubmed.ncbi.nlm.nih.gov/830208"},"language":"en","primary_location":{"id":"doi:10.1161/01.cir.55.1.195","doi":"https://doi.org/10.1161/01.cir.55.1.195","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.cir.55.1.195","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.55.1.195","source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.55.1.195","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038079151","display_name":"Jaume Figueras","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Figueras","raw_affiliation_strings":["J Figueras"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"J Figueras","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112800612","display_name":"Max Harry Weil","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M H Weil","raw_affiliation_strings":["M H Weil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M H Weil","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.2499,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.86553469,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"55","issue":"1","first_page":"195","last_page":"199"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.8583999872207642,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.8583999872207642,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12082","display_name":"Takotsubo Cardiomyopathy and Associated Phenomena","score":0.10350000113248825,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiogenic-pulmonary-edema","display_name":"cardiogenic pulmonary edema","score":0.9290000200271606},{"id":"https://openalex.org/keywords/colloid-osmotic-pressure","display_name":"colloid osmotic pressure","score":0.8939999938011169},{"id":"https://openalex.org/keywords/plasma-oncotic-pressure","display_name":"plasma oncotic pressure","score":0.9110000133514404},{"id":"https://openalex.org/keywords/plasma-proteins","display_name":"plasma proteins","score":0.6959999799728394},{"id":"https://openalex.org/keywords/hematocrit","display_name":"hematocrit","score":0.984000027179718},{"id":"https://openalex.org/keywords/transudation","display_name":"transudation","score":0.7789999842643738},{"id":"https://openalex.org/keywords/liquid-filtration","display_name":"liquid filtration","score":0.6520000100135803},{"id":"https://openalex.org/keywords/fluid-reabsorption","display_name":"fluid reabsorption","score":0.9309999942779541},{"id":"https://openalex.org/keywords/furosemide","display_name":"furosemide","score":0.8790000081062317},{"id":"https://openalex.org/keywords/morphine","display_name":"morphine","score":0.9369999766349792},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.47699999809265137}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9289819002151489},{"id":"https://openalex.org/C104471311","wikidata":"https://www.wikidata.org/wiki/Q16670987","display_name":"Oncotic pressure","level":3,"score":0.9245516061782837},{"id":"https://openalex.org/C2776468924","wikidata":"https://www.wikidata.org/wiki/Q857667","display_name":"Pulmonary edema","level":3,"score":0.8294570446014404},{"id":"https://openalex.org/C2780886150","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Edema","level":2,"score":0.6056484580039978},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5665560960769653},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5386208891868591},{"id":"https://openalex.org/C2777955127","wikidata":"https://www.wikidata.org/wiki/Q388801","display_name":"Furosemide","level":2,"score":0.5296368598937988},{"id":"https://openalex.org/C146556889","wikidata":"https://www.wikidata.org/wiki/Q1414127","display_name":"Pulmonary wedge pressure","level":3,"score":0.46933355927467346},{"id":"https://openalex.org/C2780959883","wikidata":"https://www.wikidata.org/wiki/Q111146","display_name":"Hematocrit","level":2,"score":0.45759114623069763},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4562470018863678},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.4489150643348694},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.42799314856529236},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.31509143114089966},{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001798","descriptor_name":"Blood Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003102","descriptor_name":"Colloids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005665","descriptor_name":"Furosemide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006400","descriptor_name":"Hematocrit","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009994","descriptor_name":"Osmolar Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009997","descriptor_name":"Osmotic Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010949","descriptor_name":"Plasma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011654","descriptor_name":"Pulmonary Edema","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D011654","descriptor_name":"Pulmonary Edema","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1161/01.cir.55.1.195","doi":"https://doi.org/10.1161/01.cir.55.1.195","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.cir.55.1.195","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.55.1.195","source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},{"id":"pmid:830208","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/830208","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"Journal Article"},{"id":"mag:3142419341","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/abs/10.1161/circ.55.1.830208?55/1/195=&related-urls=yes&legid=circulationaha%3B55%2F1%2F195","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null}],"best_oa_location":{"id":"doi:10.1161/01.cir.55.1.195","doi":"https://doi.org/10.1161/01.cir.55.1.195","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.cir.55.1.195","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.55.1.195","source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1990679391.pdf","grobid_xml":"https://content.openalex.org/works/W1990679391.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1513635469","https://openalex.org/W1566894921","https://openalex.org/W1957072063","https://openalex.org/W1978154934","https://openalex.org/W1983028781","https://openalex.org/W1993995599","https://openalex.org/W1994430247","https://openalex.org/W2000123435","https://openalex.org/W2004776482","https://openalex.org/W2008534964","https://openalex.org/W2015320013","https://openalex.org/W2018926789","https://openalex.org/W2032828707","https://openalex.org/W2043893950","https://openalex.org/W2055867454","https://openalex.org/W2061115958","https://openalex.org/W2069289355","https://openalex.org/W2078682555","https://openalex.org/W2118320100","https://openalex.org/W2162433124","https://openalex.org/W2269606079","https://openalex.org/W2313121787","https://openalex.org/W2398284360","https://openalex.org/W2418817841"],"related_works":["https://openalex.org/W2017981394","https://openalex.org/W2015320013","https://openalex.org/W2126734230","https://openalex.org/W2080462100","https://openalex.org/W2012182358","https://openalex.org/W2165491740","https://openalex.org/W2080885209","https://openalex.org/W2019189693","https://openalex.org/W2042571585","https://openalex.org/W2609736153"],"abstract_inverted_index":{"Colloid":[0],"osmotic":[1],"pressure":[2],"(COP)":[3],"was":[4,33,102],"measured":[5],"in":[6,28,65,71,92,104,118,132,137],"95":[7],"patients":[8,20,37,66,94,138],"with":[9,67,95,114],"clinical":[10],"and":[11,35,61,98,122,162],"radiological":[12],"evidence":[13,45],"of":[14,46,56,81,89,108,126,149,158,164,173],"acute":[15,30,41],"cardiogenic":[16,159],"pulmonary":[17,68,74,90,100,127,160,174],"edema.":[18,69,128,175],"Fifty":[19],"who":[21,38,139],"were":[22,63,76,135],"admitted":[23],"for":[24],"coronary":[25],"observation":[26],"but":[27],"whom":[29],"myocardial":[31,42],"infarctin":[32],"excluded,":[34],"21":[36],"had":[39],"sustained":[40],"infarction":[43],"without":[44],"left":[47],"ventricular":[48],"failure":[49],"served":[50],"as":[51],"controls.":[52],"Significantly":[53],"higher":[54],"values":[55],"COP,":[57,119],"total":[58,120],"plasma":[59],"protein,":[60],"hematocrit":[62,123],"observed":[64,136],"Increases":[70],"COP":[72],"during":[73,156,171],"edema":[75,91,101,161],"best":[77],"explained":[78],"by":[79],"transudation":[80],"hypooncotic":[82,109,150,165],"fluid":[83,110,151,166],"into":[84,167],"extravascular":[85,112],"spaces.":[86],"Following":[87],"treatment":[88],"76":[93],"furosemide,":[96],"morphine,":[97],"oxygen,":[99],"reversed":[103],"65":[105],"patients.":[106],"Reabsorption":[107],"from":[111,152],"sites":[113],"a":[115],"significant":[116,130],"decline":[117],"protein":[121],"followed":[124],"reversal":[125,172],"No":[129],"changes":[131],"these":[133],"parameters":[134],"failed":[140],"to":[141,143],"respond":[142],"therapy.":[144],"These":[145],"observations":[146],"implicate":[147],"filtration":[148],"the":[153,168],"intravascular":[154,169],"compartment":[155,170],"onset":[157],"reabsorption":[163]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}