{"id":"https://openalex.org/W1990642605","doi":"https://doi.org/10.1016/j.physbeh.2012.02.012","title":"Effects of leptin treatment and Western diet on wheel running in selectively bred high runner mice","display_name":"Effects of leptin treatment and Western diet on wheel running in selectively bred high runner mice","publication_year":2012,"publication_date":"2012-02-16","ids":{"openalex":"https://openalex.org/W1990642605","doi":"https://doi.org/10.1016/j.physbeh.2012.02.012","mag":"1990642605","pmid":"https://pubmed.ncbi.nlm.nih.gov/22361262"},"language":"en","primary_location":{"id":"doi:10.1016/j.physbeh.2012.02.012","doi":"https://doi.org/10.1016/j.physbeh.2012.02.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.physbeh.2012.02.012","pdf_url":null,"source":{"id":"https://openalex.org/S167407068","display_name":"Physiology & Behavior","issn_l":"0031-9384","issn":["0031-9384","1873-507X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","erih-plus","jufo-1","ki-jl-1","medline","norway-2","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiology & Behavior","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042249966","display_name":"Thomas H. Meek","orcid":"https://orcid.org/0000-0002-4922-7009","observed_orcids":["https://orcid.org/0000-0002-4922-7009"]},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Thomas H. Meek","raw_affiliation_strings":["Department of Biology, University of California, Riverside, Riverside, CA 92521, USA. thmeek@uw.edu","Department of Biology, University of California-Riverside, Riverside, CA, 92521, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of California, Riverside, Riverside, CA 92521, USA. thmeek@uw.edu","institution_ids":["https://openalex.org/I103635307"]},{"raw_affiliation_string":"Department of Biology, University of California-Riverside, Riverside, CA, 92521, USA","institution_ids":["https://openalex.org/I103635307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043142440","display_name":"Elizabeth M. Dlugosz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth M. Dlugosz","raw_affiliation_strings":["Department of Biology, University of California, Riverside, Riverside, CA 92521, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of California, Riverside, Riverside, CA 92521, USA","institution_ids":["https://openalex.org/I103635307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011373190","display_name":"Kim T. Vu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kim T. Vu","raw_affiliation_strings":["Department of Biology, University of California, Riverside, Riverside, CA 92521, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of California, Riverside, Riverside, CA 92521, USA","institution_ids":["https://openalex.org/I103635307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019388483","display_name":"Theodore Garland","orcid":"https://orcid.org/0000-0002-7916-3552","observed_orcids":["https://orcid.org/0000-0002-7916-3552"]},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theodore Garland","raw_affiliation_strings":["Department of Biology, University of California, Riverside, Riverside, CA 92521, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of California, Riverside, Riverside, CA 92521, USA","institution_ids":["https://openalex.org/I103635307"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5042249966"],"corresponding_institution_ids":["https://openalex.org/I103635307"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":0.8504,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.67907878,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"106","issue":"2","first_page":"252","last_page":"258"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/wheel-running","display_name":"wheel running","score":0.7979999780654907},{"id":"https://openalex.org/keywords/voluntary-exercise","display_name":"voluntary exercise","score":0.7549999952316284},{"id":"https://openalex.org/keywords/western-diet","display_name":"Western diet","score":0.8610000014305115},{"id":"https://openalex.org/keywords/selective-breeding","display_name":"selective breeding","score":0.6290000081062317},{"id":"https://openalex.org/keywords/energy-intake","display_name":"energy intake","score":0.9039999842643738},{"id":"https://openalex.org/keywords/body-mass","display_name":"body mass","score":0.7950000166893005},{"id":"https://openalex.org/keywords/insulin","display_name":"insulin","score":0.6110000014305115},{"id":"https://openalex.org/keywords/resistin","display_name":"resistin","score":0.8270000219345093},{"id":"https://openalex.org/keywords/glucose-dependent-insulinotropic-polypeptide","display_name":"glucose-dependent insulinotropic polypeptide","score":0.9409999847412109},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.5139999985694885},{"id":"https://openalex.org/keywords/locomotor-activity","display_name":"locomotor activity","score":0.8420000076293945},{"id":"https://openalex.org/keywords/genetic-background","display_name":"genetic background","score":0.6579999923706055}],"concepts":[{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.9481444358825684},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7689110040664673},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7547662258148193},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4503270387649536},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43420708179473877},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40389859676361084},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.32610857486724854}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002096","descriptor_name":"C-Peptide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002149","descriptor_name":"Energy Intake","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004041","descriptor_name":"Dietary Fats","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005749","descriptor_name":"Gastric Inhibitory Polypeptide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D020738","descriptor_name":"Leptin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D020738","descriptor_name":"Leptin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D052243","descriptor_name":"Resistin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.physbeh.2012.02.012","doi":"https://doi.org/10.1016/j.physbeh.2012.02.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.physbeh.2012.02.012","pdf_url":null,"source":{"id":"https://openalex.org/S167407068","display_name":"Physiology & Behavior","issn_l":"0031-9384","issn":["0031-9384","1873-507X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","erih-plus","jufo-1","ki-jl-1","medline","norway-2","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiology & Behavior","raw_type":"journal-article"},{"id":"pmid:22361262","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22361262","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiology & behavior","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9074000120162964,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332550","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43"},{"id":"https://openalex.org/F4320337399","display_name":"Division of Integrative Organismal Systems","ror":"https://ror.org/01rvays47"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W67836478","https://openalex.org/W70671500","https://openalex.org/W205125821","https://openalex.org/W1479752016","https://openalex.org/W1548178315","https://openalex.org/W1561443084","https://openalex.org/W1968055211","https://openalex.org/W1968314159","https://openalex.org/W1969099489","https://openalex.org/W1977915489","https://openalex.org/W1978485246","https://openalex.org/W1978711313","https://openalex.org/W1979174743","https://openalex.org/W1990545199","https://openalex.org/W1996493973","https://openalex.org/W1998198644","https://openalex.org/W2010602399","https://openalex.org/W2013914899","https://openalex.org/W2017421512","https://openalex.org/W2017709986","https://openalex.org/W2019118485","https://openalex.org/W2022974680","https://openalex.org/W2037331996","https://openalex.org/W2037372741","https://openalex.org/W2040798713","https://openalex.org/W2042784380","https://openalex.org/W2047662990","https://openalex.org/W2047820724","https://openalex.org/W2048047184","https://openalex.org/W2049254268","https://openalex.org/W2050639176","https://openalex.org/W2057525967","https://openalex.org/W2060682066","https://openalex.org/W2070076444","https://openalex.org/W2079395662","https://openalex.org/W2080304239","https://openalex.org/W2084590945","https://openalex.org/W2088666203","https://openalex.org/W2106225750","https://openalex.org/W2108981107","https://openalex.org/W2110501192","https://openalex.org/W2113382445","https://openalex.org/W2116068588","https://openalex.org/W2117585913","https://openalex.org/W2127555093","https://openalex.org/W2136755966","https://openalex.org/W2137902297","https://openalex.org/W2146798664","https://openalex.org/W2150568116","https://openalex.org/W2151566924","https://openalex.org/W2152832571","https://openalex.org/W2158069518","https://openalex.org/W2172115548","https://openalex.org/W2175843266","https://openalex.org/W2180277885","https://openalex.org/W2584647260","https://openalex.org/W2902146200"],"related_works":["https://openalex.org/W7098690811","https://openalex.org/W1602937610","https://openalex.org/W1996493973","https://openalex.org/W2136755966","https://openalex.org/W1963952573","https://openalex.org/W2013914899","https://openalex.org/W2471958874","https://openalex.org/W1868771870","https://openalex.org/W2109950366","https://openalex.org/W2010917587"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}