{"id":"https://openalex.org/W1990373465","doi":"https://doi.org/10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.0.co;2-e","title":"Kindled seizures increase metabotropic glutamate receptor expression and function in the rat supraoptic nucleus","display_name":"Kindled seizures increase metabotropic glutamate receptor expression and function in the rat supraoptic nucleus","publication_year":1998,"publication_date":"1998-11-01","ids":{"openalex":"https://openalex.org/W1990373465","doi":"https://doi.org/10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.0.co;2-e","mag":"1990373465","pmid":"https://pubmed.ncbi.nlm.nih.gov/9819146"},"language":"en","primary_location":{"id":"doi:10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.0.co;2-e","doi":"https://doi.org/10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.0.co;2-e","is_oa":false,"landing_page_url":"https://doi.org/10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.0.co;2-e","pdf_url":null,"source":{"id":"https://openalex.org/S76417895","display_name":"Journal of Neuroscience Research","issn_l":"0360-4012","issn":["0360-4012","1097-4547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroscience Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052285767","display_name":"Walid M. Al\u2010Ghoul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W.M. Al-Ghoul","raw_affiliation_strings":["Department of Neurology, University of North Carolina, Chapel Hill 27599, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of North Carolina, Chapel Hill 27599, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023078550","display_name":"Rick B. Meeker","orcid":"https://orcid.org/0000-0002-7487-5315","observed_orcids":["https://orcid.org/0000-0002-7487-5315"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"R.B. Meeker","raw_affiliation_strings":["Department of Neurology, University of North Carolina, Chapel Hill, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of North Carolina, Chapel Hill, North Carolina","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037746759","display_name":"Robert Greenwood","orcid":"https://orcid.org/0000-0002-6231-0253","observed_orcids":["https://orcid.org/0000-0002-6231-0253"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.S. Greenwood","raw_affiliation_strings":["Department of Neurology, University of North Carolina, Chapel Hill, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of North Carolina, Chapel Hill, North Carolina","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5023078550"],"corresponding_institution_ids":["https://openalex.org/I114027177"],"apc_list":{"value":4840,"currency":"USD","value_usd":4840},"apc_paid":null,"fwci":2.2375,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.86798702,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"54","issue":"3","first_page":"412","last_page":"423"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.6650000214576721,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.6650000214576721,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.305400013923645,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kindled-seizures","display_name":"kindled seizures","score":0.9490000009536743},{"id":"https://openalex.org/keywords/metabotropic-glutamate-receptors","display_name":"metabotropic glutamate receptors","score":0.9940000176429749},{"id":"https://openalex.org/keywords/supraoptic-nucleus","display_name":"supraoptic nucleus","score":0.8389999866485596},{"id":"https://openalex.org/keywords/vasopressin","display_name":"vasopressin","score":0.8799999952316284},{"id":"https://openalex.org/keywords/amygdala-kindling","display_name":"amygdala kindling","score":0.9259999990463257},{"id":"https://openalex.org/keywords/mglur1","display_name":"mGluR1","score":0.8619999885559082},{"id":"https://openalex.org/keywords/mglur3","display_name":"mGluR3","score":0.996999979019165},{"id":"https://openalex.org/keywords/mglur7","display_name":"mGluR7","score":0.8629999756813049},{"id":"https://openalex.org/keywords/mglur2-3","display_name":"mGluR2/3","score":0.8309999704360962},{"id":"https://openalex.org/keywords/intracellular-calcium","display_name":"intracellular calcium","score":0.781000018119812},{"id":"https://openalex.org/keywords/acpd","display_name":"ACPD","score":0.7360000014305115},{"id":"https://openalex.org/keywords/neuroendocrine-cells","display_name":"neuroendocrine cells","score":0.9449999928474426},{"id":"https://openalex.org/keywords/seizure-induced-gene-expression","display_name":"seizure-induced gene expression","score":0.49799999594688416}],"concepts":[{"id":"https://openalex.org/C49051014","wikidata":"https://www.wikidata.org/wiki/Q2033959","display_name":"Metabotropic glutamate receptor","level":4,"score":0.8776023387908936},{"id":"https://openalex.org/C207951395","wikidata":"https://www.wikidata.org/wiki/Q288431","display_name":"Metabotropic glutamate receptor 1","level":5,"score":0.7976787090301514},{"id":"https://openalex.org/C26702167","wikidata":"https://www.wikidata.org/wiki/Q901988","display_name":"Metabotropic receptor","level":4,"score":0.5324424505233765},{"id":"https://openalex.org/C119128870","wikidata":"https://www.wikidata.org/wiki/Q4859538","display_name":"Metabotropic glutamate receptor 2","level":5,"score":0.5214711427688599},{"id":"https://openalex.org/C2777687476","wikidata":"https://www.wikidata.org/wiki/Q492272","display_name":"Supraoptic nucleus","level":3,"score":0.5103217959403992},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4567412734031677},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44842463731765747},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.43814629316329956},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4178093373775482},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3960704505443573},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3909033536911011},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.30610716342926025},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2928978204727173},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14956119656562805}],"mesh":[{"descriptor_ui":"D000679","descriptor_name":"Amygdala","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003515","descriptor_name":"Cycloleucine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D003515","descriptor_name":"Cycloleucine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007696","descriptor_name":"Kindling, Neurologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013495","descriptor_name":"Supraoptic Nucleus","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D013495","descriptor_name":"Supraoptic Nucleus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013495","descriptor_name":"Supraoptic Nucleus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D017403","descriptor_name":"In Situ Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018094","descriptor_name":"Receptors, Metabotropic Glutamate","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018094","descriptor_name":"Receptors, Metabotropic Glutamate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018094","descriptor_name":"Receptors, Metabotropic Glutamate","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D020318","descriptor_name":"Rats, Long-Evans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.0.co;2-e","doi":"https://doi.org/10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.0.co;2-e","is_oa":false,"landing_page_url":"https://doi.org/10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.0.co;2-e","pdf_url":null,"source":{"id":"https://openalex.org/S76417895","display_name":"Journal of Neuroscience Research","issn_l":"0360-4012","issn":["0360-4012","1097-4547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroscience Research","raw_type":"journal-article"},{"id":"doi:10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.3.co;2-5","doi":"https://doi.org/10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.3.co;2-5","is_oa":false,"landing_page_url":"https://doi.org/10.1002/(sici)1097-4547(19981101)54:3<412::aid-jnr12>3.3.co;2-5","pdf_url":null,"source":{"id":"https://openalex.org/S76417895","display_name":"Journal of Neuroscience Research","issn_l":"0360-4012","issn":["0360-4012","1097-4547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroscience Research","raw_type":"journal-article"},{"id":"pmid:9819146","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9819146","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuroscience research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G546242809","display_name":"EXCITATORY AMINO ACID REGULATION OF VASOPRESSIN CELLS","funder_award_id":"5r01ns013411-22","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G928335950","display_name":null,"funder_award_id":"NS13411","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1489966545","https://openalex.org/W1503737839","https://openalex.org/W1594563757","https://openalex.org/W1627535048","https://openalex.org/W1833489208","https://openalex.org/W1891815016","https://openalex.org/W1967552442","https://openalex.org/W1972183007","https://openalex.org/W1973689178","https://openalex.org/W1985892733","https://openalex.org/W1986899276","https://openalex.org/W1991679043","https://openalex.org/W2003058141","https://openalex.org/W2011212122","https://openalex.org/W2022475968","https://openalex.org/W2024240338","https://openalex.org/W2030193061","https://openalex.org/W2033722720","https://openalex.org/W2043166209","https://openalex.org/W2045876524","https://openalex.org/W2048621600","https://openalex.org/W2058291949","https://openalex.org/W2058385302","https://openalex.org/W2061831839","https://openalex.org/W2064186390","https://openalex.org/W2064767806","https://openalex.org/W2067098758","https://openalex.org/W2070760008","https://openalex.org/W2075979847","https://openalex.org/W2076644208","https://openalex.org/W2088912528","https://openalex.org/W2089530794","https://openalex.org/W2090493382","https://openalex.org/W2106189180","https://openalex.org/W2118664845","https://openalex.org/W2131024077","https://openalex.org/W2140142911","https://openalex.org/W2145055014","https://openalex.org/W2160789742","https://openalex.org/W2304512189","https://openalex.org/W2399727619","https://openalex.org/W2414831233","https://openalex.org/W2415577430","https://openalex.org/W2416575665","https://openalex.org/W2473331018"],"related_works":["https://openalex.org/W2067098758","https://openalex.org/W1985892733","https://openalex.org/W2415577430","https://openalex.org/W2105487742","https://openalex.org/W2121884595","https://openalex.org/W2051385653","https://openalex.org/W2093950888","https://openalex.org/W1984494320","https://openalex.org/W2055267971","https://openalex.org/W2082158700"],"abstract_inverted_index":{"The":[0],"spread":[1],"of":[2,30,151,188,205,217],"experimentally":[3],"kindled":[4],"seizures":[5],"in":[6,9,12,19,37,53,57,67,83,86,89,107,125,127,137,148,165,191,197,202],"rats":[7],"results":[8],"sustained":[10],"increases":[11,25],"plasma":[13],"vasopressin":[14],"(VP)":[15],"and":[16,101,111,133,161,185,208],"VP":[17],"mRNA":[18,65],"the":[20,31,68,87,90,108,128,140,198,203,215],"supraoptic":[21],"nucleus":[22],"(SON).":[23],"These":[24],"provide":[26],"an":[27],"excellent":[28],"example":[29],"pathological":[32],"plasticity":[33,49],"that":[34],"can":[35],"develop":[36],"normal":[38],"cells":[39,153],"exposed":[40],"to":[41,55,139,174,214],"recurrent":[42],"seizure":[43,223],"activity.":[44,224],"To":[45],"test":[46],"whether":[47],"this":[48],"might":[50],"be":[51],"due":[52],"part":[54],"changes":[56,220],"metabotropic":[58],"glutamate":[59],"receptors":[60,211],"(mGluRs),":[61],"we":[62],"examined":[63],"mGluR":[64,78,141],"expression":[66,132,204],"SON":[69,88,109],"1":[70],"month":[71],"after":[72,114,147,170],"stage":[73],"5":[74],"amygdala":[75],"kindling.":[76,115],"Three":[77],"subtypes":[79],"were":[80,104,145,195],"detected":[81],"by":[82,154],"situ":[84],"hybridization":[85],"following":[91],"relative":[92],"levels:":[93],"mGluR3":[94,102,210],">":[95,97],"mGluR1":[96,100,118,160,207],"mGluR7.":[98],"Both":[99,193],"mRNAs":[103],"significantly":[105,123],"increased":[106,124,196],"(+28-61%)":[110],"cortex":[112],"(+27-42%)":[113],"Immunoreactivity":[116],"for":[117,159],"but":[119],"not":[120],"mGluR2/3":[121,162],"was":[122,163],"vivo":[126],"SON.":[129],"Receptor":[130],"protein":[131],"intracellular":[134,189],"calcium":[135],"accumulation":[136],"response":[138],"agonist,":[142],"1S,3R":[143,177],"ACPD,":[144],"evaluated":[146],"vitro":[149],"\"kindling\"":[150],"neuroendocrine":[152],"Mg2+":[155],"deprivation.":[156],"Increased":[157],"immunoreactivity":[158],"seen":[164],"all":[166],"cultures":[167],"3":[168],"days":[169],"a":[171],"brief":[172],"exposure":[173],"Mg2+-free":[175],"medium.":[176],"1-aminocyclopentane-1,3-dicarboxylic":[178],"acid":[179],"(ACPD)":[180],"induced":[181],"rapid":[182],"peak":[183],"responses":[184,194],"gradual":[186],"accumulations":[187],"Ca2+":[190],"neurons.":[192],"\"kindled\"":[199],"cells.":[200],"Increases":[201],"functional":[206],"perhaps":[209],"may":[212],"contribute":[213],"development":[216],"long-lasting":[218],"plastic":[219],"associated":[221],"with":[222]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}