{"id":"https://openalex.org/W1990365018","doi":"https://doi.org/10.1371/journal.pcbi.1002813","title":"Integration of the Transcriptome and Glycome for Identification of Glycan Cell Signatures","display_name":"Integration of the Transcriptome and Glycome for Identification of Glycan Cell Signatures","publication_year":2013,"publication_date":"2013-01-10","ids":{"openalex":"https://openalex.org/W1990365018","doi":"https://doi.org/10.1371/journal.pcbi.1002813","mag":"1990365018","pmid":"https://pubmed.ncbi.nlm.nih.gov/23326219","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3542073"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1002813","doi":"https://doi.org/10.1371/journal.pcbi.1002813","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002813","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002813&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","ccf-b","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002813&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074409919","display_name":"Sandra V. Bennun","orcid":"https://orcid.org/0009-0003-8720-6369","observed_orcids":["https://orcid.org/0009-0003-8720-6369"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210101611","display_name":"ReacTech (United States)","ror":"https://ror.org/00yp48s31","country_code":"US","type":"company","lineage":["https://openalex.org/I4210101611"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sandra V. Bennun","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America. svbennun@gmail.com","Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America","ReacTech Inc., Alexandria, Virginia, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America. svbennun@gmail.com","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"ReacTech Inc., Alexandria, Virginia, United States of America","institution_ids":["https://openalex.org/I4210101611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067156333","display_name":"Kevin J. Yarema","orcid":"https://orcid.org/0000-0002-4279-1459","observed_orcids":["https://orcid.org/0000-0002-4279-1459"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin J. Yarema","raw_affiliation_strings":["Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014510444","display_name":"Michael J. Betenbaugh","orcid":"https://orcid.org/0000-0002-6336-4659","observed_orcids":["https://orcid.org/0000-0002-6336-4659"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J. Betenbaugh","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033290269","display_name":"Frederick J. Krambeck","orcid":"https://orcid.org/0000-0003-3838-3775","observed_orcids":["https://orcid.org/0000-0003-3838-3775"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210101611","display_name":"ReacTech (United States)","ror":"https://ror.org/00yp48s31","country_code":"US","type":"company","lineage":["https://openalex.org/I4210101611"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frederick J. Krambeck","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America","ReacTech Inc., Alexandria, Virginia, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"ReacTech Inc., Alexandria, Virginia, United States of America","institution_ids":["https://openalex.org/I4210101611"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5074409919"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210101611"],"apc_list":{"value":3043,"currency":"USD","value_usd":3043},"apc_paid":{"value":3043,"currency":"USD","value_usd":3043},"fwci":2.7222,"has_fulltext":true,"cited_by_count":62,"citation_normalized_percentile":{"value":0.91940403,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"9","issue":"1","first_page":"e1002813","last_page":"e1002813"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/n-glycosylation","display_name":"N-glycosylation","score":0.871999979019165},{"id":"https://openalex.org/keywords/glycan-biosynthesis","display_name":"glycan biosynthesis","score":0.6769999861717224},{"id":"https://openalex.org/keywords/lncap-cells","display_name":"LNCaP cells","score":0.7039999961853027},{"id":"https://openalex.org/keywords/prostate-cancer-progression","display_name":"prostate cancer progression","score":0.7889999747276306},{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.8190000057220459},{"id":"https://openalex.org/keywords/glycan-biomarkers","display_name":"glycan biomarkers","score":0.7239999771118164},{"id":"https://openalex.org/keywords/fut1","display_name":"FUT1","score":0.6150000095367432},{"id":"https://openalex.org/keywords/mgat5","display_name":"MGAT5","score":0.8429999947547913},{"id":"https://openalex.org/keywords/glycan-epitopes","display_name":"carbohydrate epitopes","score":0.5860000252723694}],"concepts":[{"id":"https://openalex.org/C158650290","wikidata":"https://www.wikidata.org/wiki/Q3063952","display_name":"Glycome","level":4,"score":0.8861585855484009},{"id":"https://openalex.org/C206212055","wikidata":"https://www.wikidata.org/wiki/Q2553138","display_name":"Glycan","level":3,"score":0.8150505423545837},{"id":"https://openalex.org/C2777313579","wikidata":"https://www.wikidata.org/wiki/Q898365","display_name":"Glycosylation","level":2,"score":0.6771319508552551},{"id":"https://openalex.org/C106686826","wikidata":"https://www.wikidata.org/wiki/Q741206","display_name":"Glycomics","level":4,"score":0.6647226810455322},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6317025423049927},{"id":"https://openalex.org/C204641814","wikidata":"https://www.wikidata.org/wiki/Q899224","display_name":"Glycobiology","level":4,"score":0.6176635026931763},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6027837991714478},{"id":"https://openalex.org/C2779723316","wikidata":"https://www.wikidata.org/wiki/Q6459234","display_name":"LNCaP","level":4,"score":0.5814977884292603},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.4459006190299988},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.3768974542617798},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2680979371070862},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.208359956741333},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18535098433494568},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.15031787753105164},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1440521478652954},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.13677865266799927}],"mesh":[{"descriptor_ui":"D002241","descriptor_name":"Carbohydrates","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006031","descriptor_name":"Glycosylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pcbi.1002813","doi":"https://doi.org/10.1371/journal.pcbi.1002813","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002813","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002813&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","ccf-b","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2547683","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3542073","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:23326219","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23326219","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3542073","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3542073/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:cddeeac423a2421e825885b2eba762b7","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cddeeac423a2421e825885b2eba762b7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 9, Iss 1, p e1002813 (2013)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/114799","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Integration_of_the_Transcriptome_and_Glycome_for_Identification_of_Glycan_Cell_Signatures__/114799","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1002813","doi":"https://doi.org/10.1371/journal.pcbi.1002813","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002813","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002813&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","ccf-b","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6298318355","display_name":"JHU-UMD Diabetes Research Center","funder_award_id":"P30DK079637","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6619626","display_name":"Mechanism and Anti-Cancer Activity of SCFA-Hexosamine Analogs","funder_award_id":"R01CA112314","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7983805713","display_name":"Mathematical model relating gene expression to glycoform structure","funder_award_id":"R41CA127885","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8855295916","display_name":"Protein Carbohydrate Interactions in Cell Communication","funder_award_id":"U54GM062116","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1990365018.pdf","grobid_xml":"https://content.openalex.org/works/W1990365018.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W3501035","https://openalex.org/W104336579","https://openalex.org/W120175246","https://openalex.org/W1536242272","https://openalex.org/W1853970337","https://openalex.org/W1964243035","https://openalex.org/W1964816209","https://openalex.org/W1966333179","https://openalex.org/W1969592341","https://openalex.org/W1972393591","https://openalex.org/W1980541971","https://openalex.org/W1990217586","https://openalex.org/W1995243908","https://openalex.org/W2003131503","https://openalex.org/W2007519704","https://openalex.org/W2050858647","https://openalex.org/W2054931050","https://openalex.org/W2059529313","https://openalex.org/W2062440930","https://openalex.org/W2073185398","https://openalex.org/W2075672935","https://openalex.org/W2080168973","https://openalex.org/W2081352653","https://openalex.org/W2082352058","https://openalex.org/W2087070363","https://openalex.org/W2100331658","https://openalex.org/W2108244696","https://openalex.org/W2109731526","https://openalex.org/W2116222616","https://openalex.org/W2117286035","https://openalex.org/W2126040395","https://openalex.org/W2134690493","https://openalex.org/W2136408887","https://openalex.org/W2142760163","https://openalex.org/W2146795821","https://openalex.org/W2147118358","https://openalex.org/W2153389408","https://openalex.org/W2153905340","https://openalex.org/W2154258517","https://openalex.org/W2164144602","https://openalex.org/W2169026128","https://openalex.org/W2175766170","https://openalex.org/W2312972213"],"related_works":["https://openalex.org/W2147118358","https://openalex.org/W3184087830","https://openalex.org/W4400593060","https://openalex.org/W2747601729","https://openalex.org/W1931724297","https://openalex.org/W4409161305","https://openalex.org/W7107875822","https://openalex.org/W3045996369","https://openalex.org/W1898129651","https://openalex.org/W2460468455"],"abstract_inverted_index":{"Abnormalities":[0],"in":[1,23,101,113,122,130],"glycan":[2,21,79,151],"biosynthesis":[3],"have":[4],"been":[5],"conclusively":[6],"linked":[7],"to":[8,25,29,63,107],"many":[9],"diseases":[10],"but":[11],"the":[12,18,57,69,73,95,114,123,131,135,142],"complexity":[13],"of":[14,20,61,68,110,144,159,167],"glycosylation":[15,53],"has":[16],"hindered":[17],"analysis":[19],"data":[22,49,161],"order":[24],"identify":[26],"glycoforms":[27],"contributing":[28],"disease.":[30],"To":[31],"overcome":[32],"this":[33],"limitation,":[34],"we":[35],"developed":[36],"a":[37,128],"quantitative":[38],"N-glycosylation":[39,74],"model":[40,60,75,118],"that":[41],"interprets":[42],"and":[43,47,77,103,153],"integrates":[44],"mass":[45,87],"spectral":[46,88],"transcriptomic":[48],"by":[50],"incorporating":[51],"key":[52,150],"enzyme":[54],"activities.":[55],"Using":[56],"cancer":[58],"progression":[59],"androgen-dependent":[62],"androgen-independent":[64,115],"Lymph":[65],"Node":[66],"Carcinoma":[67],"Prostate":[70],"(LNCaP)":[71],"cells,":[72],"identified":[76],"quantified":[78],"structural":[80],"details":[81],"not":[82],"typically":[83],"derived":[84],"from":[85],"single-stage":[86],"or":[89],"gene":[90],"expression":[91],"data.":[92],"Differences":[93],"between":[94],"cell":[96],"types":[97],"uncovered":[98],"include":[99],"increases":[100],"H(II)":[102],"Le(y)":[104],"epitopes,":[105],"corresponding":[106],"greater":[108],"activity":[109],"\u03b12-Fuc-transferase":[111],"(FUT1)":[112],"cells.":[116],"The":[117,157],"further":[119],"elucidated":[120],"limitations":[121],"two":[124],"analytical":[125],"platforms":[126],"including":[127],"defect":[129],"microarray":[132],"for":[133,148,170],"detecting":[134],"GnTV":[136],"(MGAT5)":[137],"enzyme.":[138],"Our":[139],"results":[140],"demonstrate":[141],"potential":[143,154],"systems":[145,168],"glycobiology":[146],"tools":[147],"elucidating":[149],"biomarkers":[152],"therapeutic":[155],"targets.":[156],"integration":[158],"multiple":[160],"sets":[162],"represents":[163],"an":[164],"important":[165],"application":[166],"biology":[169],"understanding":[171],"complex":[172],"cellular":[173],"processes.":[174]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}