{"id":"https://openalex.org/W1990250249","doi":"https://doi.org/10.1021/ja993452o","title":"An Antibiotic Cloaked by Its Own Resistance Enzyme","display_name":"An Antibiotic Cloaked by Its Own Resistance Enzyme","publication_year":1999,"publication_date":"1999-12-01","ids":{"openalex":"https://openalex.org/W1990250249","doi":"https://doi.org/10.1021/ja993452o","mag":"1990250249"},"language":"en","primary_location":{"id":"doi:10.1021/ja993452o","doi":"https://doi.org/10.1021/ja993452o","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ja993452o","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038357408","display_name":"Jalal Haddad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jalal Haddad","raw_affiliation_strings":["Department of Chemistry, Wayne State University, Detroit, Michigan 48202-3489"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Wayne State University, Detroit, Michigan 48202-3489","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043351423","display_name":"Sergei B. Vakulenko","orcid":"https://orcid.org/0000-0002-5327-8124","observed_orcids":["https://orcid.org/0000-0002-5327-8124"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sergei Vakulenko","raw_affiliation_strings":["Department of Chemistry, Wayne State University, Detroit, Michigan 48202-3489"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Wayne State University, Detroit, Michigan 48202-3489","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013812375","display_name":"Shahriar Mobashery","orcid":"https://orcid.org/0000-0002-7695-7883","observed_orcids":["https://orcid.org/0000-0002-7695-7883"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shahriar Mobashery","raw_affiliation_strings":["Department of Chemistry, Wayne State University, Detroit, Michigan 48202-3489"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Wayne State University, Detroit, Michigan 48202-3489","institution_ids":["https://openalex.org/I185443292"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I185443292"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":2.9703,"has_fulltext":false,"cited_by_count":80,"citation_normalized_percentile":{"value":0.91029724,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"121","issue":"50","first_page":"11922","last_page":"11923"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.7484999895095825,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.7484999895095825,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.16689999401569366,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.007899999618530273,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antibiotic-resistance","display_name":"antibiotic resistance","score":0.75},{"id":"https://openalex.org/keywords/beta-lactamase","display_name":"beta-lactamase","score":0.7689999938011169},{"id":"https://openalex.org/keywords/antibiotic-hydrolysis","display_name":"antibiotic hydrolysis","score":0.48100000619888306},{"id":"https://openalex.org/keywords/enzyme-inhibitor-complex","display_name":"enzyme-inhibitor complex","score":0.40299999713897705},{"id":"https://openalex.org/keywords/beta-lactam-antibiotics","display_name":"beta-lactam antibiotics","score":0.652999997138977}],"concepts":[{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.7037183046340942},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.5014169216156006},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4972551167011261},{"id":"https://openalex.org/C518677369","wikidata":"https://www.wikidata.org/wiki/Q202833","display_name":"Social media","level":2,"score":0.47527235746383667},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.46825867891311646},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.4381721019744873},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3291562795639038}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/ja993452o","doi":"https://doi.org/10.1021/ja993452o","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ja993452o","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W593361858","https://openalex.org/W1508568715","https://openalex.org/W1562138142","https://openalex.org/W1567170006","https://openalex.org/W1973500454","https://openalex.org/W2005605166","https://openalex.org/W2031232438","https://openalex.org/W2038014125","https://openalex.org/W2046129015","https://openalex.org/W2117204128","https://openalex.org/W2469884426","https://openalex.org/W2492507518","https://openalex.org/W2498763738","https://openalex.org/W2499315139","https://openalex.org/W2951207033","https://openalex.org/W4211254771","https://openalex.org/W4294555143"],"related_works":["https://openalex.org/W2069966411","https://openalex.org/W4245137541","https://openalex.org/W2002681531","https://openalex.org/W11813446","https://openalex.org/W4296639073","https://openalex.org/W4244211283","https://openalex.org/W4241243252","https://openalex.org/W2093801665","https://openalex.org/W4248880661","https://openalex.org/W2017955739"],"abstract_inverted_index":{"ADVERTISEMENT":[0],"RETURN":[1],"TO":[2],"ISSUEPREVCommunicationNEXTAn":[3],"Antibiotic":[4],"Cloaked":[5],"by":[6,111],"Its":[7],"Own":[8],"Resistance":[9],"EnzymeJalal":[10],"Haddad,":[11],"Sergei":[12],"Vakulenko,":[13],"and":[14,79,84,113,157,174,190,192,211,214],"Shahriar":[15],"MobasheryView":[16],"Author":[17],"Information":[18,206,208],"Department":[19],"of":[20,69,104,130],"Chemistry,":[21],"Wayne":[22],"State":[23],"University":[24],"Detroit,":[25],"Michigan":[26],"48202-3489":[27],"Cite":[28],"this:":[29],"J.":[30],"Am.":[31],"Chem.":[32],"Soc.":[33],"1999,":[34],"121,":[35],"50,":[36],"11922\u201311923Publication":[37],"Date":[38],"(Web):December":[39],"4,":[40],"1999Publication":[41],"History":[42],"Received23":[43],"September":[44],"1999Published":[45,48],"online4":[46],"December":[47,51],"inissue":[49],"1":[50],"1999https://doi.org/10.1021/ja993452oCopyright":[52],"\u00a9":[53],"1999":[54],"American":[55],"Chemical":[56],"SocietyRIGHTS":[57],"&":[58],"PERMISSIONSArticle":[59],"Views571Altmetric-Citations68LEARN":[60],"ABOUT":[61],"THESE":[62],"METRICSArticle":[63],"Views":[64],"are":[65,88,101],"the":[66,97,102,131,142,155,158,163,170,176],"COUNTER-compliant":[67],"sum":[68],"full":[70],"text":[71],"article":[72,136],"downloads":[73],"since":[74],"November":[75],"2008":[76],"(both":[77],"PDF":[78],"HTML)":[80],"across":[81],"all":[82],"institutions":[83],"individuals.":[85],"These":[86],"metrics":[87],"regularly":[89],"updated":[90,114],"to":[91,96],"reflect":[92],"usage":[93],"leading":[94],"up":[95],"last":[98],"few":[99],"days.Citations":[100],"number":[103],"other":[105],"articles":[106],"citing":[107],"this":[108],"article,":[109],"calculated":[110],"Crossref":[112,120],"daily.":[115],"Find":[116,166],"more":[117,167],"information":[118,168],"about":[119,154],"citation":[121],"counts.The":[122],"Altmetric":[123,171],"Attention":[124,172],"Score":[125,173],"is":[126,178],"a":[127,134,147],"quantitative":[128],"measure":[129],"attention":[132],"that":[133],"research":[135],"has":[137],"received":[138],"online.":[139],"Clicking":[140],"on":[141,169],"donut":[143],"icon":[144],"will":[145],"load":[146],"page":[148],"at":[149],"altmetric.com":[150],"with":[151,186],"additional":[152],"details":[153],"score":[156,177],"social":[159],"media":[160],"presence":[161],"for":[162],"given":[164],"article.":[165],"how":[175],"calculated.":[179],"Share":[180,195],"Add":[181],"toView":[182],"InAdd":[183],"Full":[184],"Text":[185],"ReferenceAdd":[187],"Description":[188],"ExportRISCitationCitation":[189],"abstractCitation":[191],"referencesMore":[193],"Options":[194],"onFacebookTwitterWechatLinked":[196],"InReddit":[197],"Read":[198],"OnlinePDF":[199],"(138":[200],"KB)":[201],"Get":[202,216],"e-AlertscloseSupporting":[203],"Info":[204],"(1)\u00bbSupporting":[205],"Supporting":[207],"SUBJECTS:Antimicrobial":[209],"agents,Carbohydrates,Cell":[210],"molecular":[212],"biology,Peptides":[213],"proteins,Phosphates":[215],"e-Alerts":[217]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}