{"id":"https://openalex.org/W1990216353","doi":"https://doi.org/10.2307/3578829","title":"Radiosensitivity of Testicular Cells in the Prepubertal Mouse","display_name":"Radiosensitivity of Testicular Cells in the Prepubertal Mouse","publication_year":1994,"publication_date":"1994-09-01","ids":{"openalex":"https://openalex.org/W1990216353","doi":"https://doi.org/10.2307/3578829","mag":"1990216353","pmid":"https://pubmed.ncbi.nlm.nih.gov/8073114"},"language":"en","primary_location":{"id":"doi:10.2307/3578829","doi":"https://doi.org/10.2307/3578829","is_oa":false,"landing_page_url":"https://doi.org/10.2307/3578829","pdf_url":null,"source":{"id":"https://openalex.org/S152208300","display_name":"Radiation Research","issn_l":"0033-7587","issn":["0033-7587","1938-5404"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315745","host_organization_name":"Radiation Research Society","host_organization_lineage":["https://openalex.org/P4310315745"],"host_organization_lineage_names":["Radiation Research Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000134032","display_name":"R. P. F. A. Vergouwen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"R. P. F. A. Vergouwen","raw_affiliation_strings":["University of Utrecht, Department of Cell Biology, Medical School, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Utrecht, Department of Cell Biology, Medical School, The Netherlands","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081111677","display_name":"R. Huiskamp","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Huiskamp","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036443584","display_name":"R. J. Bas","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. J. Bas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000755399","display_name":"Hermien L. Roepers\u2010Gajadien","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. L. Roepers-Gajadien","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087549185","display_name":"Frank H. de Jong","orcid":"https://orcid.org/0000-0003-3578-1065","observed_orcids":["https://orcid.org/0000-0003-3578-1065"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. H. de Jong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091649463","display_name":"Frank J. C. M. Van Eerdenburg","orcid":"https://orcid.org/0000-0002-6024-6905","observed_orcids":["https://orcid.org/0000-0002-6024-6905"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. J. C. M. van Eerdenburg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113651264","display_name":"Jan A. G. Davids","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. A. G. Davids","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5055162786","display_name":"Dirk G. de Rooij","orcid":"https://orcid.org/0000-0003-3932-4419","observed_orcids":["https://orcid.org/0000-0003-3932-4419"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. G. de Rooij","raw_affiliation_strings":["Other departments"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Other departments","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.1802545,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"139","issue":"3","first_page":"316","last_page":"316"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9003999829292297,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9003999829292297,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.0778999999165535,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.011699999682605267,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiosensitivity","display_name":"radiosensitivity","score":0.8399999737739563},{"id":"https://openalex.org/keywords/prepubertal-testis","display_name":"prepubertal testis","score":0.9210000038146973},{"id":"https://openalex.org/keywords/spermatogonial-stem-cells","display_name":"spermatogonial stem cells","score":0.9679999947547913},{"id":"https://openalex.org/keywords/x-ray-irradiation","display_name":"X-ray irradiation","score":0.7239999771118164},{"id":"https://openalex.org/keywords/total-body-irradiation","display_name":"total body irradiation","score":0.7490000128746033},{"id":"https://openalex.org/keywords/d0-value","display_name":"D0 value","score":0.7059999704360962},{"id":"https://openalex.org/keywords/sertoli-cells","display_name":"Sertoli cells","score":0.9419999718666077},{"id":"https://openalex.org/keywords/leydig-cells","display_name":"Leydig cells","score":0.9810000061988831},{"id":"https://openalex.org/keywords/testicular-cell-types","display_name":"testicular cell types","score":0.609000027179718},{"id":"https://openalex.org/keywords/plasma-testosterone-levels","display_name":"plasma testosterone","score":0.6700000166893005}],"concepts":[{"id":"https://openalex.org/C206684579","wikidata":"https://www.wikidata.org/wiki/Q4387689","display_name":"Radiosensitivity","level":3,"score":0.8657659292221069},{"id":"https://openalex.org/C2781068068","wikidata":"https://www.wikidata.org/wiki/Q195614","display_name":"Sertoli cell","level":3,"score":0.7700619697570801},{"id":"https://openalex.org/C2777736315","wikidata":"https://www.wikidata.org/wiki/Q636846","display_name":"Leydig cell","level":4,"score":0.7637471556663513},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6242078542709351},{"id":"https://openalex.org/C58962609","wikidata":"https://www.wikidata.org/wiki/Q2353022","display_name":"Radioresistance","level":3,"score":0.6151759028434753},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5896187424659729},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.5680943131446838},{"id":"https://openalex.org/C2780918802","wikidata":"https://www.wikidata.org/wiki/Q25091543","display_name":"Repopulation","level":4,"score":0.5315567851066589},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5241832137107849},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5176668763160706},{"id":"https://openalex.org/C2779066085","wikidata":"https://www.wikidata.org/wiki/Q9384","display_name":"Testicle","level":2,"score":0.47280874848365784},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.4696585237979889},{"id":"https://openalex.org/C181152851","wikidata":"https://www.wikidata.org/wiki/Q712604","display_name":"Lymphatic system","level":2,"score":0.4341471195220947},{"id":"https://openalex.org/C123765429","wikidata":"https://www.wikidata.org/wiki/Q36961","display_name":"Spermatogenesis","level":2,"score":0.3293550908565521},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.2554154694080353},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.23684066534042358},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.19539326429367065},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1525392234325409},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.14987456798553467},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.14406991004943848},{"id":"https://openalex.org/C2778575703","wikidata":"https://www.wikidata.org/wiki/Q50265477","display_name":"Luteinizing hormone","level":3,"score":0.08607614040374756},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D007985","descriptor_name":"Leydig Cells","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008808","descriptor_name":"Mice, Inbred CBA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D012708","descriptor_name":"Sertoli Cells","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D013093","descriptor_name":"Spermatogonia","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D014965","descriptor_name":"X-Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.2307/3578829","doi":"https://doi.org/10.2307/3578829","is_oa":false,"landing_page_url":"https://doi.org/10.2307/3578829","pdf_url":null,"source":{"id":"https://openalex.org/S152208300","display_name":"Radiation Research","issn_l":"0033-7587","issn":["0033-7587","1938-5404"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315745","host_organization_name":"Radiation Research Society","host_organization_lineage":["https://openalex.org/P4310315745"],"host_organization_lineage_names":["Radiation Research Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation Research","raw_type":"journal-article"},{"id":"pmid:8073114","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8073114","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation research","raw_type":"Journal Article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire_cris_publications/c9b0457c-8a3e-4cd9-9d45-f0b8679c269d","doi":null,"is_oa":false,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/c9b0457c-8a3e-4cd9-9d45-f0b8679c269d","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vergouwen, R P, Huiskamp, R, Bas, R J, Roepers-Gajadien, H L, de Jong, F H, van Eerdenburg, F J, Davids, J A & de rooij, D G 1994, 'Radiosensitivity of testicular cells in the prepubertal mouse', Radiation research, vol. 139, no. 3, pp. 316-326. https://doi.org/10.2307/3578829","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:amcpub:oai:pure.amc.nl:publications/6cde2823-87cf-4156-bdc7-d1250edef8f3","doi":null,"is_oa":false,"landing_page_url":"https://pure.amc.nl/en/publications/radiosensitivity-of-testicular-cells-in-the-prepubertal-mouse(6cde2823-87cf-4156-bdc7-d1250edef8f3).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Radiation research, 139(3), 316 - 326. Radiation Research Society","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W15882602","https://openalex.org/W22122640","https://openalex.org/W1497136075","https://openalex.org/W1550106832","https://openalex.org/W1553744647","https://openalex.org/W1602040572","https://openalex.org/W1930774224","https://openalex.org/W1963794548","https://openalex.org/W1976268179","https://openalex.org/W1980434262","https://openalex.org/W1980921839","https://openalex.org/W1983969174","https://openalex.org/W2001087432","https://openalex.org/W2014466828","https://openalex.org/W2018663321","https://openalex.org/W2029944658","https://openalex.org/W2032676551","https://openalex.org/W2044674829","https://openalex.org/W2047417172","https://openalex.org/W2054568324","https://openalex.org/W2057185316","https://openalex.org/W2071409493","https://openalex.org/W2076950917","https://openalex.org/W2087281694","https://openalex.org/W2104047635","https://openalex.org/W2111647115","https://openalex.org/W2118628520","https://openalex.org/W2131727903","https://openalex.org/W2154838812","https://openalex.org/W2159127559","https://openalex.org/W2332422205","https://openalex.org/W2396660559"],"related_works":["https://openalex.org/W1992491661","https://openalex.org/W2049377682","https://openalex.org/W2075115403","https://openalex.org/W2332422205","https://openalex.org/W2396660559","https://openalex.org/W2066028896","https://openalex.org/W2030423650","https://openalex.org/W2073851597","https://openalex.org/W1976268179","https://openalex.org/W2136018070"],"abstract_inverted_index":{"The":[0,148],"effects":[1],"of":[2,10,33,55,63,93,125,197,206],"total-body":[3],"X":[4,34],"irradiation":[5,44,119],"on":[6],"the":[7,11,45,53,56,69,81,91,94,99,110,145,161,190,195,198,207],"prepubertal":[8,100,162,191,199],"testis":[9,102,124,201],"CBA/P":[12],"mouse":[13,101,200,209],"have":[14],"been":[15],"studied.":[16],"At":[17,40],"either":[18],"day":[19,22,73,85],"14":[20,74],"or":[21,115],"29":[23,86],"post":[24,75,87],"partum":[25,76],"male":[26],"mice":[27],"were":[28,142,171],"exposed":[29],"to":[30,51,106,156,183,186,204],"single":[31],"doses":[32,184],"rays":[35],"ranging":[36],"from":[37],"1.5-6.0":[38],"Gy.":[39],"1":[41],"week":[42],"after":[43,118,181],"repopulation":[46],"index":[47],"method":[48],"was":[49,66],"used":[50],"study":[52],"radiosensitivity":[54,92],"spermatogonial":[57,95],"stem":[58,70,82,96],"cells.":[59],"A":[60],"D0":[61],"value":[62],"1.8":[64],"Gy":[65,188],"determined":[67,143],"for":[68,80],"cells":[71,83,97,141,150],"at":[72,84],"as":[77,79],"well":[78],"partum,":[88],"indicating":[89,173],"that":[90,107,174,205],"in":[98,109,167],"is":[103,176,202],"already":[104],"comparable":[105,203],"observed":[108],"adult":[111,208],"mouse.":[112],"One,":[113],"2":[114],"3":[116],"weeks":[117],"total":[120],"cell":[121,153,179],"numbers":[122],"per":[123],"Sertoli":[126,149],"cells,":[127,129,131,134,137],"Leydig":[128,178],"mesenchymal":[130],"macrophages,":[132],"myoid":[133],"lymphatic":[135],"endothelial":[136],"endothelium":[138],"and":[139,151],"perivascular":[140],"using":[144],"disector":[146],"method.":[147],"interstitial":[152],"types":[154],"appeared":[155],"be":[157],"relatively":[158],"radioresistant":[159],"during":[160,189],"period.":[163,192],"No":[164],"significant":[165],"changes":[166],"plasma":[168],"testosterone":[169],"levels":[170],"found,":[172],"there":[175],"no":[177],"dysfunction":[180],"exposure":[182],"up":[185],"6":[187],"Taken":[193],"together,":[194],"radioresponse":[196],"testis.":[210]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}