{"id":"https://openalex.org/W1990201756","doi":"https://doi.org/10.1002/(sici)1520-6327(1998)38:1<19::aid-arch3>3.0.co;2-q","title":"Novel insecticidal peptides fromTegenaria agrestis spider venom may have a direct effect on the insect central nervous system","display_name":"Novel insecticidal peptides fromTegenaria agrestis spider venom may have a direct effect on the insect central nervous system","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W1990201756","doi":"https://doi.org/10.1002/(sici)1520-6327(1998)38:1<19::aid-arch3>3.0.co;2-q","mag":"1990201756","pmid":"https://pubmed.ncbi.nlm.nih.gov/9589602"},"language":"en","primary_location":{"id":"doi:10.1002/(sici)1520-6327(1998)38:1<19::aid-arch3>3.0.co;2-q","doi":"https://doi.org/10.1002/(sici)1520-6327(1998)38:1<19::aid-arch3>3.0.co;2-q","is_oa":false,"landing_page_url":"https://doi.org/10.1002/(sici)1520-6327(1998)38:1<19::aid-arch3>3.0.co;2-q","pdf_url":null,"source":{"id":"https://openalex.org/S14369749","display_name":"Archives of Insect Biochemistry and Physiology","issn_l":"0739-4462","issn":["0739-4462","1520-6327"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Insect Biochemistry and Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100924103","display_name":"JANICE H. JOHNSON","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Janice H. Johnson","raw_affiliation_strings":["NPS Pharmaceuticals, Salt Lake City, Utah 84108, USA. jdelmar@npsp.com","NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NPS Pharmaceuticals, Salt Lake City, Utah 84108, USA. jdelmar@npsp.com","institution_ids":[]},{"raw_affiliation_string":"NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064850975","display_name":"Jeffrey R. Bloomquist","orcid":"https://orcid.org/0000-0002-9136-4998","observed_orcids":["https://orcid.org/0000-0002-9136-4998"]},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey R. Bloomquist","raw_affiliation_strings":["Department of Entomology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Entomology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059664265","display_name":"Karen J. Krapcho","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Karen J. Krapcho","raw_affiliation_strings":["NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062407821","display_name":"Robert M. Kral","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert M. Kral","raw_affiliation_strings":["NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060272330","display_name":"Rich Trovato","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rich Trovato","raw_affiliation_strings":["NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048441010","display_name":"Kathryn G. Eppler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathryn G. Eppler","raw_affiliation_strings":["NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009699749","display_name":"Terry K. Morgan","orcid":"https://orcid.org/0000-0003-0742-5012","observed_orcids":["https://orcid.org/0000-0003-0742-5012"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Terry K. Morgan","raw_affiliation_strings":["NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089127732","display_name":"Eric G. DelMar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eric G. DelMar","raw_affiliation_strings":["NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NPS Pharmaceuticals, 420 Chipeta Way, Salt Lake City, Utah","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100924103"],"corresponding_institution_ids":[],"apc_list":{"value":3920,"currency":"USD","value_usd":3920},"apc_paid":null,"fwci":0.5835,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.66690941,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"38","issue":"1","first_page":"19","last_page":"31"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11353","display_name":"Venomous Animal Envenomation and Studies","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11353","display_name":"Venomous Animal Envenomation and Studies","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.007000000216066837,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11075","display_name":"Insect Resistance and Genetics","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spider-venom","display_name":"spider venom","score":0.9309999942779541},{"id":"https://openalex.org/keywords/insecticidal-peptides","display_name":"insecticidal peptides","score":0.8429999947547913},{"id":"https://openalex.org/keywords/insect-central-nervous-system","display_name":"insect central nervous system","score":0.8109999895095825},{"id":"https://openalex.org/keywords/housefly-larvae","display_name":"housefly larvae","score":0.7440000176429749},{"id":"https://openalex.org/keywords/caterpillars","display_name":"caterpillars","score":0.8700000047683716},{"id":"https://openalex.org/keywords/venom-fractionation","display_name":"venom fractionation","score":0.5770000219345093},{"id":"https://openalex.org/keywords/cdna-cloning","display_name":"cDNA cloning","score":0.7509999871253967}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8441030383110046},{"id":"https://openalex.org/C2779448229","wikidata":"https://www.wikidata.org/wiki/Q3386847","display_name":"Venom","level":2,"score":0.7875401973724365},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.6499282121658325},{"id":"https://openalex.org/C2777612826","wikidata":"https://www.wikidata.org/wiki/Q1390","display_name":"Insect","level":2,"score":0.6327545046806335},{"id":"https://openalex.org/C2780181586","wikidata":"https://www.wikidata.org/wiki/Q3966705","display_name":"Spider","level":2,"score":0.45667123794555664},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.4373728632926941},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.43475422263145447},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4310232698917389},{"id":"https://openalex.org/C2777773057","wikidata":"https://www.wikidata.org/wiki/Q2492887","display_name":"Spodoptera","level":4,"score":0.4276719093322754},{"id":"https://openalex.org/C2779341487","wikidata":"https://www.wikidata.org/wiki/Q1375305","display_name":"Trichoplusia","level":4,"score":0.41427645087242126},{"id":"https://openalex.org/C15358309","wikidata":"https://www.wikidata.org/wiki/Q24780345","display_name":"Spider toxin","level":4,"score":0.4105813503265381},{"id":"https://openalex.org/C173758957","wikidata":"https://www.wikidata.org/wiki/Q129270","display_name":"Larva","level":2,"score":0.31536442041397095},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.28345316648483276},{"id":"https://openalex.org/C2778350275","wikidata":"https://www.wikidata.org/wiki/Q459180","display_name":"Noctuidae","level":3,"score":0.19849076867103577},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.18184393644332886},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.11085501313209534},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09172070026397705},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0902847945690155},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.08324569463729858},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001517","descriptor_name":"Coleoptera","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001517","descriptor_name":"Coleoptera","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001517","descriptor_name":"Coleoptera","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001681","descriptor_name":"Biological Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001681","descriptor_name":"Biological Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001681","descriptor_name":"Biological Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005591","descriptor_name":"Chemical Fractionation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005591","descriptor_name":"Chemical Fractionation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005591","descriptor_name":"Chemical Fractionation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006793","descriptor_name":"Houseflies","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006793","descriptor_name":"Houseflies","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006793","descriptor_name":"Houseflies","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009036","descriptor_name":"Moths","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009036","descriptor_name":"Moths","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009036","descriptor_name":"Moths","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013111","descriptor_name":"Spider Venoms","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D013111","descriptor_name":"Spider Venoms","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D013111","descriptor_name":"Spider Venoms","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D013111","descriptor_name":"Spider Venoms","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D013111","descriptor_name":"Spider Venoms","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D013111","descriptor_name":"Spider Venoms","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D013111","descriptor_name":"Spider Venoms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013111","descriptor_name":"Spider Venoms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013111","descriptor_name":"Spider Venoms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013112","descriptor_name":"Spiders","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013112","descriptor_name":"Spiders","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013112","descriptor_name":"Spiders","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/(sici)1520-6327(1998)38:1<19::aid-arch3>3.0.co;2-q","doi":"https://doi.org/10.1002/(sici)1520-6327(1998)38:1<19::aid-arch3>3.0.co;2-q","is_oa":false,"landing_page_url":"https://doi.org/10.1002/(sici)1520-6327(1998)38:1<19::aid-arch3>3.0.co;2-q","pdf_url":null,"source":{"id":"https://openalex.org/S14369749","display_name":"Archives of Insect Biochemistry and Physiology","issn_l":"0739-4462","issn":["0739-4462","1520-6327"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Insect Biochemistry and Physiology","raw_type":"journal-article"},{"id":"pmid:9589602","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9589602","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of insect biochemistry and physiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/15","score":0.5199999809265137,"display_name":"Life on land"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310164","display_name":"Texas A and M University","ror":"https://ror.org/01f5ytq51"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1485066469","https://openalex.org/W1511678313","https://openalex.org/W1524624799","https://openalex.org/W1557004700","https://openalex.org/W1584095986","https://openalex.org/W1976734142","https://openalex.org/W1978217041","https://openalex.org/W1978538042","https://openalex.org/W1981159024","https://openalex.org/W1987513835","https://openalex.org/W1992688643","https://openalex.org/W1993438237","https://openalex.org/W2003702564","https://openalex.org/W2010632030","https://openalex.org/W2028461059","https://openalex.org/W2029891516","https://openalex.org/W2030905289","https://openalex.org/W2033285343","https://openalex.org/W2040253039","https://openalex.org/W2045629573","https://openalex.org/W2054008617","https://openalex.org/W2062829057","https://openalex.org/W2064877498","https://openalex.org/W2068175109","https://openalex.org/W2084087308","https://openalex.org/W2089520622","https://openalex.org/W2092284863","https://openalex.org/W2108388593","https://openalex.org/W2122925309","https://openalex.org/W2134812217","https://openalex.org/W2356400847","https://openalex.org/W4244676685","https://openalex.org/W4294216491"],"related_works":["https://openalex.org/W4362611952","https://openalex.org/W1983830022","https://openalex.org/W2068175109","https://openalex.org/W2053953401","https://openalex.org/W2004976979","https://openalex.org/W7096960305","https://openalex.org/W575628402","https://openalex.org/W4235666122","https://openalex.org/W164252842","https://openalex.org/W2028719849"],"abstract_inverted_index":{"Fractionation":[0],"of":[1,13,16,39,45,109,123],"venom":[2],"from":[3,34,74,101,125],"an":[4,92,120],"agelenid":[5],"spider,":[6],"Tegenaria":[7,89],"agrestis,":[8],"resulted":[9],"in":[10,113,153],"the":[11,69,87,148,168],"isolation":[12],"a":[14,107,154],"family":[15],"three":[17],"peptides":[18],"with":[19,96],"potent":[20],"insecticidal":[21,88,160],"activity.":[22],"These":[23],"peptide":[24,161],"toxins,":[25,68],"TaITX-1,":[26],"-2,":[27],"and":[28,57,83],"-3,":[29],"whose":[30],"sequences":[31],"were":[32,133,142],"revealed":[33],"cloned":[35],"cDNAs,":[36],"each":[37],"consist":[38],"50":[40],"amino":[41],"acid":[42],"residues,":[43],"six":[44],"which":[46],"are":[47,72],"cysteines.":[48],"They":[49],"appear":[50],"to":[51,103],"be":[52],"amidated":[53],"at":[54],"their":[55],"C-termini":[56],"exhibit":[58],"greater":[59],"than":[60],"90%":[61],"sequence":[62],"identity.":[63],"Unlike":[64],"other":[65],"reported":[66,158],"spider":[67],"TaI":[70,149],"toxins":[71,90,118,150],"processed":[73],"precursors":[75],"containing":[76],"no":[77],"propeptide":[78],"sequences.":[79],"In":[80,106],"lepidopteran":[81],"larvae":[82],"corn":[84],"rootworm":[85],"beetles,":[86],"caused":[91,119],"unusual":[93],"excitatory":[94],"symptomatology":[95],"50%":[97],"paralytic":[98],"doses":[99],"ranging":[100],"0.23":[102],"2.6":[104],"nmol/g.":[105],"series":[108],"electrophysiological":[110],"experiments":[111],"performed":[112],"house":[114],"fly":[115],"larvae,":[116],"these":[117],"elevated":[121],"rate":[122],"firing":[124],"central":[126,170],"nervous":[127,171],"system":[128],"neurons.":[129],"No":[130],"significant":[131],"effects":[132],"found":[134],"when":[135],"any":[136],"peripheral":[137],"sensory":[138],"or":[139],"motor":[140],"systems":[141],"examined.":[143],"Thus,":[144],"it":[145],"appears":[146],"that":[147],"may":[151,164],"act":[152,165],"fashion":[155],"not":[156],"previously":[157],"for":[159],"toxins;":[162],"they":[163],"directly":[166],"on":[167],"insect":[169],"system.":[172]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-23T05:00:35.095934","created_date":"2016-06-24T00:00:00"}