{"id":"https://openalex.org/W1990103493","doi":"https://doi.org/10.1021/np010095y","title":"Thalibealine, a Novel Tetrahydroprotoberberine\u2212Aporphine Dimeric Alkaloid from Thalictrum wangii","display_name":"Thalibealine, a Novel Tetrahydroprotoberberine\u2212Aporphine Dimeric Alkaloid from Thalictrum wangii","publication_year":2001,"publication_date":"2001-05-31","ids":{"openalex":"https://openalex.org/W1990103493","doi":"https://doi.org/10.1021/np010095y","mag":"1990103493","pmid":"https://pubmed.ncbi.nlm.nih.gov/11421755"},"language":"en","primary_location":{"id":"doi:10.1021/np010095y","doi":"https://doi.org/10.1021/np010095y","is_oa":false,"landing_page_url":"https://doi.org/10.1021/np010095y","pdf_url":null,"source":{"id":"https://openalex.org/S166799026","display_name":"Journal of Natural Products","issn_l":"0163-3864","issn":["0163-3864","1520-6025"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Natural Products","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037591141","display_name":"Tawfeq A. Al\u2010Howiriny","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tawfeq A. Al-Howiriny","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033621394","display_name":"Michael A. Zemaitis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael A. Zemaitis","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016064026","display_name":"Cong-yuan Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cong-yuan Gao","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062638238","display_name":"Chad E. Hadden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chad E. Hadden","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086697076","display_name":"Gary E. Martin","orcid":"https://orcid.org/0000-0003-0750-3041","observed_orcids":["https://orcid.org/0000-0003-0750-3041"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary E. Martin","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111750655","display_name":"Fu\u2010Tyan Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fu-tyan Lin","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110114140","display_name":"Paul L. Schiff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Paul L. Schiff","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Spectral Analysis, Beijing Medical University, Beijing, 100083, People's Republic of China, Pharmaceutical Development, Pharmacia Corporation, Kalamazoo, Michigan 49001, and Department of Chemistry, Faculty of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260","institution_ids":["https://openalex.org/I170201317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110114140"],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.6084,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.69342748,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"64","issue":"6","first_page":"819","last_page":"822"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12059","display_name":"Berberine and alkaloids research","score":0.9312000274658203,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12059","display_name":"Berberine and alkaloids research","score":0.9312000274658203,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12497","display_name":"Traditional and Medicinal Uses of Annonaceae","score":0.029999999329447746,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.009399999864399433,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dimeric-alkaloids","display_name":"dimeric alkaloids","score":0.8610000014305115},{"id":"https://openalex.org/keywords/tetrahydroprotoberberines","display_name":"tetrahydroprotoberberines","score":0.9549999833106995},{"id":"https://openalex.org/keywords/aporphine-alkaloids","display_name":"aporphine alkaloids","score":0.9049999713897705},{"id":"https://openalex.org/keywords/magnoflorine","display_name":"magnoflorine","score":0.9890000224113464},{"id":"https://openalex.org/keywords/berberine","display_name":"berberine","score":0.9940000176429749},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.6840000152587891},{"id":"https://openalex.org/keywords/natural-product-isolation","display_name":"natural product isolation","score":0.7260000109672546}],"concepts":[{"id":"https://openalex.org/C2778079118","wikidata":"https://www.wikidata.org/wiki/Q4780565","display_name":"Aporphine","level":3,"score":0.9364554286003113},{"id":"https://openalex.org/C2777667214","wikidata":"https://www.wikidata.org/wiki/Q70702","display_name":"Alkaloid","level":2,"score":0.8096688389778137},{"id":"https://openalex.org/C2780116568","wikidata":"https://www.wikidata.org/wiki/Q176525","display_name":"Berberine","level":2,"score":0.7378427386283875},{"id":"https://openalex.org/C2779411416","wikidata":"https://www.wikidata.org/wiki/Q145869","display_name":"Ranunculaceae","level":2,"score":0.6458355188369751},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.6200755834579468},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5857853293418884},{"id":"https://openalex.org/C2779546866","wikidata":"https://www.wikidata.org/wiki/Q531306","display_name":"Dimer","level":2,"score":0.5820748805999756},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1876424252986908},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.16792398691177368},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.09547290205955505}],"mesh":[{"descriptor_ui":"D001600","descriptor_name":"Berberine Alkaloids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001600","descriptor_name":"Berberine Alkaloids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001600","descriptor_name":"Berberine Alkaloids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002855","descriptor_name":"Chromatography, Thin Layer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002855","descriptor_name":"Chromatography, Thin Layer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002855","descriptor_name":"Chromatography, Thin Layer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010946","descriptor_name":"Plants, Medicinal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010946","descriptor_name":"Plants, Medicinal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010946","descriptor_name":"Plants, Medicinal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013056","descriptor_name":"Spectrophotometry, Ultraviolet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013056","descriptor_name":"Spectrophotometry, Ultraviolet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013056","descriptor_name":"Spectrophotometry, Ultraviolet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018517","descriptor_name":"Plant Roots","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018517","descriptor_name":"Plant Roots","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018517","descriptor_name":"Plant Roots","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/np010095y","doi":"https://doi.org/10.1021/np010095y","is_oa":false,"landing_page_url":"https://doi.org/10.1021/np010095y","pdf_url":null,"source":{"id":"https://openalex.org/S166799026","display_name":"Journal of Natural Products","issn_l":"0163-3864","issn":["0163-3864","1520-6025"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Natural Products","raw_type":"journal-article"},{"id":"pmid:11421755","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11421755","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of natural products","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/15","display_name":"Life on land","score":0.4699999988079071}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1800331116","https://openalex.org/W2037862780","https://openalex.org/W2062370885","https://openalex.org/W2066232721","https://openalex.org/W2318006168","https://openalex.org/W2331349411","https://openalex.org/W2679933436"],"related_works":["https://openalex.org/W1992559039","https://openalex.org/W2019459611","https://openalex.org/W2040533699","https://openalex.org/W2044452441","https://openalex.org/W2057113280","https://openalex.org/W2951572399","https://openalex.org/W2026711834","https://openalex.org/W4224113838","https://openalex.org/W4229059603","https://openalex.org/W1990103493"],"abstract_inverted_index":{"A":[0],"novel":[1],"tetrahydroprotoberberine-aporphine":[2,47],"dimeric":[3],"alkaloid,":[4],"(-)-thalibealine":[5],"(1),":[6],"was":[7],"isolated":[8],"from":[9,49,60],"the":[10,28,32,36,41,54],"roots":[11],"of":[12,45,58],"Thalictrum":[13,61],"wangiii,":[14],"and":[15,35],"its":[16],"structure":[17],"established":[18],"via":[19],"spectroscopic":[20],"analysis.":[21],"Three":[22],"other":[23],"alkaloids":[24],"were":[25],"isolated,":[26],"including":[27],"benzyltetrahydroisoquinoline-aporphine":[29],"dimer":[30,48],"(+)-thalmelatidine,":[31],"aporphine":[33],"(+)-magnoflorine,":[34],"protoberberine":[37],"berberine.":[38],"This":[39],"is":[40],"first":[42,55],"reported":[43,56],"isolation":[44,57],"a":[46],"nature,":[50],"as":[51,53],"well":[52],"constituents":[59],"wangii.":[62]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2016-06-24T00:00:00"}