{"id":"https://openalex.org/W1989463753","doi":"https://doi.org/10.1111/j.1750-3639.2003.tb00009.x","title":"Astrocyte Activation and Apoptosis: Their Roles in the Neuropathology of HIV Infection","display_name":"Astrocyte Activation and Apoptosis: Their Roles in the Neuropathology of HIV Infection","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W1989463753","doi":"https://doi.org/10.1111/j.1750-3639.2003.tb00009.x","mag":"1989463753","pmid":"https://pubmed.ncbi.nlm.nih.gov/12580548","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8095843"},"language":"en","primary_location":{"id":"doi:10.1111/j.1750-3639.2003.tb00009.x","doi":"https://doi.org/10.1111/j.1750-3639.2003.tb00009.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1750-3639.2003.tb00009.x","pdf_url":null,"source":{"id":"https://openalex.org/S9094144","display_name":"Brain Pathology","issn_l":"1015-6305","issn":["1015-6305","1750-3639"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Pathology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8095843","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052453485","display_name":"Farideh Sabri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Farideh Sabri","raw_affiliation_strings":["Microbiology and Tumor Biology Center, Karolinska Institute, Nobels v\u00e4g 16, S-17177 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Tumor Biology Center, Karolinska Institute, Nobels v\u00e4g 16, S-17177 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014015676","display_name":"Kehmia Titanji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Kehmia Titanji","raw_affiliation_strings":["Microbiology and Tumor Biology Center, Karolinska Institute, Nobels va\u0308g 16, S-17177 Stockholm, Sweden","Microbiology and Tumor Biology Center, Karolinska Institute, Nobels v\u00e4g 16, S-17177 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Tumor Biology Center, Karolinska Institute, Nobels va\u0308g 16, S-17177 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Microbiology and Tumor Biology Center, Karolinska Institute, Nobels v\u00e4g 16, S-17177 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041516398","display_name":"Angelo De Milito","orcid":"https://orcid.org/0000-0003-2591-2914","observed_orcids":["https://orcid.org/0000-0003-2591-2914"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Angelo De Milito","raw_affiliation_strings":["Microbiology and Tumor Biology Center, Karolinska Institute, Nobels va\u0308g 16, S-17177 Stockholm, Sweden","Microbiology and Tumor Biology Center, Karolinska Institute, Nobels v\u00e4g 16, S-17177 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Tumor Biology Center, Karolinska Institute, Nobels va\u0308g 16, S-17177 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Microbiology and Tumor Biology Center, Karolinska Institute, Nobels v\u00e4g 16, S-17177 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055230480","display_name":"Francesca Chiodi","orcid":"https://orcid.org/0000-0002-1385-8343","observed_orcids":["https://orcid.org/0000-0002-1385-8343"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Francesca Chiodi","raw_affiliation_strings":["Microbiology and Tumor Biology Center, Karolinska Institute, Nobels va\u0308g 16, S-17177 Stockholm, Sweden","Microbiology and Tumor Biology Center, Karolinska Institute, Nobels v\u00e4g 16, S-17177 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Tumor Biology Center, Karolinska Institute, Nobels va\u0308g 16, S-17177 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Microbiology and Tumor Biology Center, Karolinska Institute, Nobels v\u00e4g 16, S-17177 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5055230480"],"corresponding_institution_ids":["https://openalex.org/I28166907"],"apc_list":{"value":4080,"currency":"USD","value_usd":4080},"apc_paid":null,"fwci":1.2953,"has_fulltext":false,"cited_by_count":88,"citation_normalized_percentile":{"value":0.76397516,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"13","issue":"1","first_page":"84","last_page":"94"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9434000253677368,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9434000253677368,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.04450000077486038,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/astrocyte-activation","display_name":"astrocyte activation","score":0.9810000061988831},{"id":"https://openalex.org/keywords/astrocyte-apoptosis","display_name":"astrocyte apoptosis","score":0.9789999723434448},{"id":"https://openalex.org/keywords/hiv-associated-neurocognitive-disorders","display_name":"HIV-associated neurocognitive disorders","score":0.8500000238418579},{"id":"https://openalex.org/keywords/fas-pathway","display_name":"Fas pathway","score":0.9330000281333923},{"id":"https://openalex.org/keywords/astrocyte-proliferation","display_name":"astrocyte proliferation","score":0.9660000205039978},{"id":"https://openalex.org/keywords/cerebrospinal-fluid-biomarkers","display_name":"cerebrospinal fluid biomarkers","score":0.9879999756813049},{"id":"https://openalex.org/keywords/highly-active-antiretroviral-therapy","display_name":"highly active antiretroviral therapy","score":0.7279999852180481},{"id":"https://openalex.org/keywords/t-cell-apoptosis","display_name":"T cell apoptosis","score":0.7409999966621399},{"id":"https://openalex.org/keywords/hiv-neuropathology","display_name":"HIV neuropathology","score":0.8410000205039978}],"concepts":[{"id":"https://openalex.org/C2779965356","wikidata":"https://www.wikidata.org/wiki/Q4811564","display_name":"Astrogliosis","level":3,"score":0.9782921075820923},{"id":"https://openalex.org/C2777542381","wikidata":"https://www.wikidata.org/wiki/Q502961","display_name":"Astrocyte","level":3,"score":0.8056038022041321},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.7028282880783081},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5393872261047363},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.525657057762146},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5224199295043945},{"id":"https://openalex.org/C2780130745","wikidata":"https://www.wikidata.org/wiki/Q1650750","display_name":"Neuropathology","level":3,"score":0.5108013153076172},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4436948299407959},{"id":"https://openalex.org/C2777682930","wikidata":"https://www.wikidata.org/wiki/Q1531490","display_name":"Gliosis","level":2,"score":0.42268407344818115},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.4156280755996704},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.34930163621902466},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2378992736339569},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.21966704726219177},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.20741859078407288},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.1098196804523468},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005911","descriptor_name":"Gliosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005911","descriptor_name":"Gliosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005911","descriptor_name":"Gliosis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019014","descriptor_name":"fas Receptor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019707","descriptor_name":"Receptors, Chemokine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D023241","descriptor_name":"Antiretroviral Therapy, Highly Active","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1750-3639.2003.tb00009.x","doi":"https://doi.org/10.1111/j.1750-3639.2003.tb00009.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1750-3639.2003.tb00009.x","pdf_url":null,"source":{"id":"https://openalex.org/S9094144","display_name":"Brain Pathology","issn_l":"1015-6305","issn":["1015-6305","1750-3639"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Pathology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8095843","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8095843","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Pathol","raw_type":"Text"},{"id":"pmid:12580548","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12580548","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain pathology (Zurich, Switzerland)","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8095843","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8095843","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Pathol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W124123819","https://openalex.org/W146744780","https://openalex.org/W1482688899","https://openalex.org/W1487397714","https://openalex.org/W1490297746","https://openalex.org/W1513727309","https://openalex.org/W1521936885","https://openalex.org/W1522823711","https://openalex.org/W1564489838","https://openalex.org/W1590295419","https://openalex.org/W1629086159","https://openalex.org/W1644579564","https://openalex.org/W1651324749","https://openalex.org/W1940105614","https://openalex.org/W1940897091","https://openalex.org/W1961326234","https://openalex.org/W1963857988","https://openalex.org/W1965588086","https://openalex.org/W1971091859","https://openalex.org/W1973792489","https://openalex.org/W1975291295","https://openalex.org/W1976471805","https://openalex.org/W1977395550","https://openalex.org/W1978456149","https://openalex.org/W1978759399","https://openalex.org/W1979491836","https://openalex.org/W2002733542","https://openalex.org/W2002946039","https://openalex.org/W2004667045","https://openalex.org/W2004992894","https://openalex.org/W2009361016","https://openalex.org/W2011168214","https://openalex.org/W2012694713","https://openalex.org/W2017523469","https://openalex.org/W2017840093","https://openalex.org/W2019143025","https://openalex.org/W2020214100","https://openalex.org/W2021151285","https://openalex.org/W2025554920","https://openalex.org/W2030692398","https://openalex.org/W2037089067","https://openalex.org/W2038752308","https://openalex.org/W2042418839","https://openalex.org/W2047953178","https://openalex.org/W2053066952","https://openalex.org/W2059030666","https://openalex.org/W2061095891","https://openalex.org/W2061497413","https://openalex.org/W2062643827","https://openalex.org/W2062704228","https://openalex.org/W2069166243","https://openalex.org/W2070647368","https://openalex.org/W2079723431","https://openalex.org/W2080254122","https://openalex.org/W2081200884","https://openalex.org/W2087343656","https://openalex.org/W2098393319","https://openalex.org/W2101446275","https://openalex.org/W2105833580","https://openalex.org/W2107755945","https://openalex.org/W2114601677","https://openalex.org/W2116130201","https://openalex.org/W2117390254","https://openalex.org/W2120862840","https://openalex.org/W2122310985","https://openalex.org/W2122845027","https://openalex.org/W2124561991","https://openalex.org/W2132586158","https://openalex.org/W2135146079","https://openalex.org/W2144414931","https://openalex.org/W2146384070","https://openalex.org/W2147638621","https://openalex.org/W2155018885","https://openalex.org/W2156945570","https://openalex.org/W2158544535","https://openalex.org/W2160030189","https://openalex.org/W2162205099","https://openalex.org/W2168945225","https://openalex.org/W2169241566","https://openalex.org/W2178964873","https://openalex.org/W2182036820","https://openalex.org/W2317271918","https://openalex.org/W2322485212","https://openalex.org/W2334281801","https://openalex.org/W4253997186","https://openalex.org/W4312955417","https://openalex.org/W4313341495"],"related_works":["https://openalex.org/W1991956638","https://openalex.org/W2335552127","https://openalex.org/W1976471805","https://openalex.org/W2019248029","https://openalex.org/W2004997979","https://openalex.org/W2041476640","https://openalex.org/W4249467054","https://openalex.org/W2953847566","https://openalex.org/W2158544535","https://openalex.org/W2900199650"],"abstract_inverted_index":{"Astrogliosis":[0],"is":[1],"a":[2,43],"common":[3],"neuropathological":[4],"finding":[5],"in":[6,29,73,106,116],"the":[7,26,30,47,63,68,74,82,95,113,125],"brains":[8],"of":[9,17,32,36,45,49,54,65,70,84,94,104,127],"HIV":[10,39,120,133],"infected":[11],"individuals;":[12],"both":[13],"activation":[14,87,101],"and":[15,34,41,102,135],"apoptosis":[16,35,103,118],"astrocytes":[18,37],"are":[19,60],"seen.":[20],"This":[21],"review":[22],"aims":[23],"to":[24,80,99,111,124],"discuss":[25],"Fas":[27],"pathway":[28],"context":[31],"proliferation":[33],"during":[38,88,119],"infection,":[40,121],"as":[42],"result":[44],"astrogliosis,":[46],"dysregulation":[48],"astrocyte-neuron":[50],"networks.":[51],"The":[52],"presence":[53],"molecules":[55,114],"reflecting":[56],"astrocyte":[57],"activation,":[58],"which":[59],"derived":[61],"from":[62,67],"solubilization":[64],"receptor/ligand":[66],"surface":[69],"proliferating":[71],"astrocytes,":[72,105],"cerebrospinal":[75],"fluid":[76],"may":[77,122],"be":[78],"used":[79],"evaluate":[81],"degree":[83],"brain":[85],"cell":[86],"HAART":[89],"therapy.":[90],"A":[91],"better":[92],"understanding":[93],"molecular":[96],"pathway(s)":[97],"leading":[98],"increase":[100],"parallel":[107],"with":[108],"studies":[109],"conducted":[110],"unravel":[112],"involved":[115],"T-cell":[117],"lead":[123],"development":[126],"new":[128],"therapeutic":[129],"strategies":[130],"for":[131],"controlling":[132],"replication":[134],"tissue":[136],"damage.":[137]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":6},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}