{"id":"https://openalex.org/W1989367285","doi":"https://doi.org/10.1007/bf00689448","title":"Kinetics of mitotic arrest and apoptosis in murine mammary and ovarian tumors treated with taxol","display_name":"Kinetics of mitotic arrest and apoptosis in murine mammary and ovarian tumors treated with taxol","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W1989367285","doi":"https://doi.org/10.1007/bf00689448","mag":"1989367285","pmid":"https://pubmed.ncbi.nlm.nih.gov/7828272"},"language":"en","primary_location":{"id":"doi:10.1007/bf00689448","doi":"https://doi.org/10.1007/bf00689448","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00689448","pdf_url":null,"source":{"id":"https://openalex.org/S117498271","display_name":"Cancer Chemotherapy and Pharmacology","issn_l":"0344-5704","issn":["0344-5704","1432-0843"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Chemotherapy and Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108796110","display_name":"Luka Milas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luka Milas","raw_affiliation_strings":["Department of Experimental Radiotherapy (66), University of Texas M. D. Anderson Cancer Center, Houston 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Radiotherapy (66), University of Texas M. D. Anderson Cancer Center, Houston 77030","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111443360","display_name":"Nancy R. Hunter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy R. Hunter","raw_affiliation_strings":["Department of Experimental Radiotherapy (66), The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, 77030, Houston, TX, USA","The University of Texas M.D. Anderson Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Radiotherapy (66), The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, 77030, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"The University of Texas M.D. Anderson Cancer Center","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079135575","display_name":"Belma Kurdoglu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Belma Kurdoglu","raw_affiliation_strings":["Department of Experimental Radiotherapy (66), The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, 77030, Houston, TX, USA","The University of Texas M.D. Anderson Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Radiotherapy (66), The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, 77030, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"The University of Texas M.D. Anderson Cancer Center","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012911897","display_name":"Kathryn A. Mason","orcid":"https://orcid.org/0000-0003-2639-1575","observed_orcids":["https://orcid.org/0000-0003-2639-1575"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kathryn A. Mason","raw_affiliation_strings":["Department of Experimental Radiotherapy (66), The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, 77030, Houston, TX, USA","The University of Texas M.D. Anderson Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Radiotherapy (66), The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, 77030, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"The University of Texas M.D. Anderson Cancer Center","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111506784","display_name":"Raymond E. Meyn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raymond E. Meyn","raw_affiliation_strings":["Department of Experimental Radiotherapy (66), The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, 77030, Houston, TX, USA","The University of Texas M.D. Anderson Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Radiotherapy (66), The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, 77030, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"The University of Texas M.D. Anderson Cancer Center","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103563066","display_name":"L. Clifton Stephens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. C. Stephens","raw_affiliation_strings":["Department of Veterinary Medicine and Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA","The University of Texas M.D. Anderson Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Medicine and Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"The University of Texas M.D. Anderson Cancer Center","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111959261","display_name":"Lester J. Peters","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lester J. Peters","raw_affiliation_strings":["Department of Clinical Radiotherapy, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA","The University of Texas M.D. Anderson Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Radiotherapy, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"The University of Texas M.D. Anderson Cancer Center","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1343551460"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":3.2414,"has_fulltext":false,"cited_by_count":184,"citation_normalized_percentile":{"value":0.92193836,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"35","issue":"4","first_page":"297","last_page":"303"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.5893999934196472,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.5893999934196472,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11752","display_name":"Cancer Treatment and Pharmacology","score":0.4077000021934509,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paclitaxel","display_name":"paclitaxel","score":0.9860000014305115},{"id":"https://openalex.org/keywords/mitotic-arrest","display_name":"mitotic arrest","score":0.9980000257492065},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.8130000233650208},{"id":"https://openalex.org/keywords/ovarian-carcinoma","display_name":"ovarian carcinoma","score":0.9819999933242798},{"id":"https://openalex.org/keywords/antitumor-efficacy","display_name":"antitumor efficacy","score":0.8880000114440918},{"id":"https://openalex.org/keywords/mitotic-index","display_name":"mitotic index","score":0.7710000276565552},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.36800000071525574},{"id":"https://openalex.org/keywords/tumor-growth-kinetics","display_name":"tumor growth kinetics","score":0.5170000195503235}],"concepts":[{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.6929604411125183},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6800962686538696},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6200866103172302},{"id":"https://openalex.org/C2778001805","wikidata":"https://www.wikidata.org/wiki/Q189961","display_name":"Mammary gland","level":4,"score":0.4469602406024933},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44629204273223877},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3433557152748108},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3193904161453247},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.23223483562469482},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.22348129749298096},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.17403897643089294},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11168283224105835}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008325","descriptor_name":"Mammary Neoplasms, Experimental","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008325","descriptor_name":"Mammary Neoplasms, Experimental","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008809","descriptor_name":"Mice, Inbred C3H","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008938","descriptor_name":"Mitosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017239","descriptor_name":"Paclitaxel","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/bf00689448","doi":"https://doi.org/10.1007/bf00689448","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00689448","pdf_url":null,"source":{"id":"https://openalex.org/S117498271","display_name":"Cancer Chemotherapy and Pharmacology","issn_l":"0344-5704","issn":["0344-5704","1432-0843"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Chemotherapy and Pharmacology","raw_type":"journal-article"},{"id":"doi:10.1007/s002800050236","doi":"https://doi.org/10.1007/s002800050236","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s002800050236","pdf_url":null,"source":{"id":"https://openalex.org/S117498271","display_name":"Cancer Chemotherapy and Pharmacology","issn_l":"0344-5704","issn":["0344-5704","1432-0843"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Chemotherapy and Pharmacology","raw_type":"journal-article"},{"id":"pmid:7828272","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7828272","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer chemotherapy and pharmacology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2178416488","display_name":"Extension of Radiotherapy Research","funder_award_id":"P01CA006294","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000878657","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA016672","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"},{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W57954726","https://openalex.org/W138721869","https://openalex.org/W1481358348","https://openalex.org/W1571233136","https://openalex.org/W1919221066","https://openalex.org/W2003422693","https://openalex.org/W2015288633","https://openalex.org/W2020796092","https://openalex.org/W2067299834","https://openalex.org/W2081406767","https://openalex.org/W2084609653","https://openalex.org/W2132574756","https://openalex.org/W4293311245","https://openalex.org/W4299315002","https://openalex.org/W4300155938"],"related_works":["https://openalex.org/W1980923728","https://openalex.org/W2364856246","https://openalex.org/W3038307504","https://openalex.org/W1995242738","https://openalex.org/W94322121","https://openalex.org/W2033799417","https://openalex.org/W2026238154","https://openalex.org/W2089161819","https://openalex.org/W1971822154","https://openalex.org/W33023422"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}