{"id":"https://openalex.org/W1988056396","doi":"https://doi.org/10.1016/j.jacc.2012.12.018","title":"Metformin Impairs Vascular Endothelial Recovery After Stent Placement in the Setting of Locally Eluted Mammalian Target of Rapamycin Inhibitors Via S6 Kinase-Dependent Inhibition of Cell Proliferation","display_name":"Metformin Impairs Vascular Endothelial Recovery After Stent Placement in the Setting of Locally Eluted Mammalian Target of Rapamycin Inhibitors Via S6 Kinase-Dependent Inhibition of Cell Proliferation","publication_year":2013,"publication_date":"2013-02-25","ids":{"openalex":"https://openalex.org/W1988056396","doi":"https://doi.org/10.1016/j.jacc.2012.12.018","mag":"1988056396","pmid":"https://pubmed.ncbi.nlm.nih.gov/23449430","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3942872"},"language":"en","primary_location":{"id":"doi:10.1016/j.jacc.2012.12.018","doi":"https://doi.org/10.1016/j.jacc.2012.12.018","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2012.12.018","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0735109713000193/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S0735109713000193/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043809413","display_name":"Anwer Habib","orcid":"https://orcid.org/0000-0002-3693-1224","observed_orcids":["https://orcid.org/0000-0002-3693-1224"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anwer Habib","raw_affiliation_strings":["Department of Internal Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067649857","display_name":"Vinit Karmali","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vinit Karmali","raw_affiliation_strings":["Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044374576","display_name":"Rohini Polavarapu","orcid":"https://orcid.org/0000-0002-2320-6103","observed_orcids":["https://orcid.org/0000-0002-2320-6103"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rohini Polavarapu","raw_affiliation_strings":["Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008489130","display_name":"Hirokuni Akahori","orcid":"https://orcid.org/0000-0003-3680-5719","observed_orcids":["https://orcid.org/0000-0003-3680-5719"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hirokuni Akahori","raw_affiliation_strings":["Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072323000","display_name":"Masataka Nakano","orcid":"https://orcid.org/0009-0006-9884-2768","observed_orcids":["https://orcid.org/0009-0006-9884-2768"]},"institutions":[{"id":"https://openalex.org/I4210135350","display_name":"CVPath Institute","ror":"https://ror.org/03gbzhd34","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210135350"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Masataka Nakano","raw_affiliation_strings":["CVPath Institute, Inc., Gaithersburg, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CVPath Institute, Inc., Gaithersburg, Maryland","institution_ids":["https://openalex.org/I4210135350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084430681","display_name":"Saami K. Yazdani","orcid":"https://orcid.org/0000-0002-9719-6382","observed_orcids":["https://orcid.org/0000-0002-9719-6382"]},"institutions":[{"id":"https://openalex.org/I4210135350","display_name":"CVPath Institute","ror":"https://ror.org/03gbzhd34","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210135350"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saami Yazdani","raw_affiliation_strings":["CVPath Institute, Inc., Gaithersburg, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CVPath Institute, Inc., Gaithersburg, Maryland","institution_ids":["https://openalex.org/I4210135350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044666284","display_name":"Fumiyuki Otsuka","orcid":"https://orcid.org/0000-0003-4162-2036","observed_orcids":["https://orcid.org/0000-0003-4162-2036"]},"institutions":[{"id":"https://openalex.org/I4210135350","display_name":"CVPath Institute","ror":"https://ror.org/03gbzhd34","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210135350"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fumiyuki Otsuka","raw_affiliation_strings":["CVPath Institute, Inc., Gaithersburg, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CVPath Institute, Inc., Gaithersburg, Maryland","institution_ids":["https://openalex.org/I4210135350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019215867","display_name":"Kim Pachura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kim Pachura","raw_affiliation_strings":["Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006723799","display_name":"Talina Davis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Talina Davis","raw_affiliation_strings":["Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000545244","display_name":"Jagat Narula","orcid":"https://orcid.org/0000-0002-0280-3996","observed_orcids":["https://orcid.org/0000-0002-0280-3996"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jagat Narula","raw_affiliation_strings":["Department of Internal Medicine, Mount Sinai School of Medicine, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Mount Sinai School of Medicine, New York, New York","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068524141","display_name":"Frank D. Kolodgie","orcid":"https://orcid.org/0000-0002-6007-2044","observed_orcids":["https://orcid.org/0000-0002-6007-2044"]},"institutions":[{"id":"https://openalex.org/I4210135350","display_name":"CVPath Institute","ror":"https://ror.org/03gbzhd34","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210135350"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frank D. Kolodgie","raw_affiliation_strings":["CVPath Institute, Inc., Gaithersburg, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CVPath Institute, Inc., Gaithersburg, Maryland","institution_ids":["https://openalex.org/I4210135350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071287538","display_name":"Renu Virmani","orcid":"https://orcid.org/0000-0003-1879-0015","observed_orcids":["https://orcid.org/0000-0003-1879-0015"]},"institutions":[{"id":"https://openalex.org/I4210135350","display_name":"CVPath Institute","ror":"https://ror.org/03gbzhd34","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210135350"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Renu Virmani","raw_affiliation_strings":["CVPath Institute, Inc., Gaithersburg, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CVPath Institute, Inc., Gaithersburg, Maryland","institution_ids":["https://openalex.org/I4210135350"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062478846","display_name":"Aloke Virmani Finn","orcid":"https://orcid.org/0000-0003-0359-0184","observed_orcids":["https://orcid.org/0000-0003-0359-0184"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Aloke V. Finn","raw_affiliation_strings":["Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5062478846"],"corresponding_institution_ids":["https://openalex.org/I150468666"],"apc_list":{"value":7166,"currency":"USD","value_usd":7166},"apc_paid":null,"fwci":5.5409,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.957599,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"61","issue":"9","first_page":"971","last_page":"980"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metformin","display_name":"metformin","score":1.0},{"id":"https://openalex.org/keywords/drug-eluting-stents","display_name":"drug-eluting stents","score":0.9769999980926514},{"id":"https://openalex.org/keywords/zotarolimus-eluting-stent","display_name":"zotarolimus-eluting stent","score":0.8709999918937683},{"id":"https://openalex.org/keywords/rapamycin","display_name":"rapamycin","score":0.9639999866485596},{"id":"https://openalex.org/keywords/mtor-inhibitors","display_name":"mTOR inhibitors","score":0.8920000195503235},{"id":"https://openalex.org/keywords/s6-kinase","display_name":"S6 kinase","score":0.9539999961853027},{"id":"https://openalex.org/keywords/endothelialization","display_name":"endothelialization","score":0.8859999775886536},{"id":"https://openalex.org/keywords/endothelial-cell-proliferation","display_name":"endothelial cell proliferation","score":0.9800000190734863},{"id":"https://openalex.org/keywords/cyclin-d1","display_name":"cyclin D1","score":0.8669999837875366},{"id":"https://openalex.org/keywords/drug-drug-interactions","display_name":"drug-drug interactions","score":0.781000018119812},{"id":"https://openalex.org/keywords/stent-thrombosis","display_name":"stent thrombosis","score":0.890999972820282},{"id":"https://openalex.org/keywords/diabetic-patients","display_name":"diabetic patients","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8370932936668396},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.6980979442596436},{"id":"https://openalex.org/C104202773","wikidata":"https://www.wikidata.org/wiki/Q18031289","display_name":"P70-S6 Kinase 1","level":4,"score":0.6919130086898804},{"id":"https://openalex.org/C2777921159","wikidata":"https://www.wikidata.org/wiki/Q32089","display_name":"Sirolimus","level":2,"score":0.6614260673522949},{"id":"https://openalex.org/C2780323712","wikidata":"https://www.wikidata.org/wiki/Q19484","display_name":"Metformin","level":3,"score":0.5315805673599243},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5183466672897339},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.5129877924919128},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.45143821835517883},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.43964868783950806},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.32474377751350403},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2654246687889099},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.23470696806907654},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2189292311668396},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10148200392723083},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.08851033449172974},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08022227883338928}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007083","descriptor_name":"Iliac Artery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008687","descriptor_name":"Metformin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D008687","descriptor_name":"Metformin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019893","descriptor_name":"Ribosomal Protein S6 Kinases","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D019893","descriptor_name":"Ribosomal Protein S6 Kinases","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020123","descriptor_name":"Sirolimus","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D020123","descriptor_name":"Sirolimus","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D020123","descriptor_name":"Sirolimus","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D054855","descriptor_name":"Drug-Eluting Stents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jacc.2012.12.018","doi":"https://doi.org/10.1016/j.jacc.2012.12.018","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2012.12.018","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0735109713000193/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},{"id":"pmid:23449430","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23449430","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2928549","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3942872","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3942872","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3942872","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Am Coll Cardiol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.jacc.2012.12.018","doi":"https://doi.org/10.1016/j.jacc.2012.12.018","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2012.12.018","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0735109713000193/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8760825607","display_name":"mTOR Signaling and Vascular Repair in an Experimental Model of Diabetes Mellitus","funder_award_id":"R01HL096970","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320310567","display_name":"Boston Scientific Corporation","ror":"https://ror.org/0385es521"},{"id":"https://openalex.org/F4320325270","display_name":"Terumo","ror":null},{"id":"https://openalex.org/F4320325446","display_name":"Biosensors International Group","ror":"https://ror.org/04bynv497"},{"id":"https://openalex.org/F4320330831","display_name":"OrbusNeich Medical","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332389","display_name":"St. Jude Medical","ror":"https://ror.org/00t9de449"},{"id":"https://openalex.org/F4320333259","display_name":"Abbott Vascular","ror":"https://ror.org/05d67dc31"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1988056396.pdf","grobid_xml":"https://content.openalex.org/works/W1988056396.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W9453318","https://openalex.org/W131092126","https://openalex.org/W1974130263","https://openalex.org/W1993222177","https://openalex.org/W1998877815","https://openalex.org/W1999999605","https://openalex.org/W2011424260","https://openalex.org/W2017331038","https://openalex.org/W2020474316","https://openalex.org/W2020844485","https://openalex.org/W2027717053","https://openalex.org/W2031726018","https://openalex.org/W2044138231","https://openalex.org/W2052223356","https://openalex.org/W2061556888","https://openalex.org/W2064656431","https://openalex.org/W2081920342","https://openalex.org/W2085567056","https://openalex.org/W2086338749","https://openalex.org/W2093664485","https://openalex.org/W2096237432","https://openalex.org/W2098930497","https://openalex.org/W2110443482","https://openalex.org/W2114391822","https://openalex.org/W2114949482","https://openalex.org/W2117748926","https://openalex.org/W2126783165","https://openalex.org/W2129585918","https://openalex.org/W2135265732","https://openalex.org/W2138226825","https://openalex.org/W2144209522","https://openalex.org/W2146415848","https://openalex.org/W2146743728","https://openalex.org/W2153371758","https://openalex.org/W2153607816","https://openalex.org/W2169226612"],"related_works":["https://openalex.org/W7717711","https://openalex.org/W1998512403","https://openalex.org/W2087092889","https://openalex.org/W2090469370","https://openalex.org/W2791258661","https://openalex.org/W2803897732","https://openalex.org/W7120570093","https://openalex.org/W3007110402","https://openalex.org/W2883573389","https://openalex.org/W3026510307"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":7}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}