{"id":"https://openalex.org/W1987343103","doi":"https://doi.org/10.1210/endo.139.10.6238","title":"The Pulsatile Characteristics of Hypothalamo-Pituitary-Adrenal Activity in Female Lewis and Fischer 344 Rats and Its Relationship to Differential Stress Responses","display_name":"The Pulsatile Characteristics of Hypothalamo-Pituitary-Adrenal Activity in Female Lewis and Fischer 344 Rats and Its Relationship to Differential Stress Responses","publication_year":1998,"publication_date":"1998-10-01","ids":{"openalex":"https://openalex.org/W1987343103","doi":"https://doi.org/10.1210/endo.139.10.6238","mag":"1987343103","pmid":"https://pubmed.ncbi.nlm.nih.gov/9751481"},"language":"en","primary_location":{"id":"doi:10.1210/endo.139.10.6238","doi":"https://doi.org/10.1210/endo.139.10.6238","is_oa":false,"landing_page_url":"https://doi.org/10.1210/endo.139.10.6238","pdf_url":null,"source":{"id":"https://openalex.org/S157527038","display_name":"Endocrinology","issn_l":"0013-7227","issn":["0013-7227","1945-7170"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089859138","display_name":"RJ Windle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802901496","display_name":"Bristol Royal Infirmary","ror":"https://ror.org/031p4kj21","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802901496","https://openalex.org/I4405276282"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"R. J. Windle","raw_affiliation_strings":["Neuroendocrine Research Group, Department of Anatomy, School of Medical Sciences (R.J.W., S.A.W., C.D.I.), Bristol, United Kingdom BS8 1TD;","The Department of Medicine, University of Bristol, Bristol Royal Infirmary (R.J.W., S.A.W., S.L.L.), Bristol, United Kingdom BS2 8HW"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroendocrine Research Group, Department of Anatomy, School of Medical Sciences (R.J.W., S.A.W., C.D.I.), Bristol, United Kingdom BS8 1TD;","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"The Department of Medicine, University of Bristol, Bristol Royal Infirmary (R.J.W., S.A.W., S.L.L.), Bristol, United Kingdom BS2 8HW","institution_ids":["https://openalex.org/I2802901496","https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108224944","display_name":"S. A. Wood","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802901496","display_name":"Bristol Royal Infirmary","ror":"https://ror.org/031p4kj21","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802901496","https://openalex.org/I4405276282"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. A. Wood","raw_affiliation_strings":["Neuroendocrine Research Group, Department of Anatomy, School of Medical Sciences (R.J.W., S.A.W., C.D.I.), Bristol, United Kingdom BS8 1TD;","The Department of Medicine, University of Bristol, Bristol Royal Infirmary (R.J.W., S.A.W., S.L.L.), Bristol, United Kingdom BS2 8HW"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroendocrine Research Group, Department of Anatomy, School of Medical Sciences (R.J.W., S.A.W., C.D.I.), Bristol, United Kingdom BS8 1TD;","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"The Department of Medicine, University of Bristol, Bristol Royal Infirmary (R.J.W., S.A.W., S.L.L.), Bristol, United Kingdom BS2 8HW","institution_ids":["https://openalex.org/I2802901496","https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017571758","display_name":"Stafford Louis Lightman","orcid":"https://orcid.org/0000-0002-8546-9646","observed_orcids":["https://orcid.org/0000-0002-8546-9646"]},"institutions":[{"id":"https://openalex.org/I2802901496","display_name":"Bristol Royal Infirmary","ror":"https://ror.org/031p4kj21","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802901496","https://openalex.org/I4405276282"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. L. Lightman","raw_affiliation_strings":["The Department of Medicine, University of Bristol, Bristol Royal Infirmary (R.J.W., S.A.W., S.L.L.), Bristol, United Kingdom BS2 8HW"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Medicine, University of Bristol, Bristol Royal Infirmary (R.J.W., S.A.W., S.L.L.), Bristol, United Kingdom BS2 8HW","institution_ids":["https://openalex.org/I2802901496","https://openalex.org/I36234482"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003145112","display_name":"Colin D Ingram","orcid":"https://orcid.org/0000-0001-6434-3350","observed_orcids":["https://orcid.org/0000-0001-6434-3350"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C. D. Ingram","raw_affiliation_strings":["Neuroendocrine Research Group, Department of Anatomy, School of Medical Sciences (R.J.W., S.A.W., C.D.I.), Bristol, United Kingdom BS8 1TD;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroendocrine Research Group, Department of Anatomy, School of Medical Sciences (R.J.W., S.A.W., C.D.I.), Bristol, United Kingdom BS8 1TD;","institution_ids":["https://openalex.org/I36234482"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5089859138"],"corresponding_institution_ids":["https://openalex.org/I2802901496","https://openalex.org/I36234482"],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":2.5282,"has_fulltext":false,"cited_by_count":203,"citation_normalized_percentile":{"value":0.89381443,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"139","issue":"10","first_page":"4044","last_page":"4052"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.9670000076293945},{"id":"https://openalex.org/keywords/circadian-variation","display_name":"circadian variation","score":0.7900000214576721},{"id":"https://openalex.org/keywords/corticotropin-releasing-factor","display_name":"corticotropin-releasing factor","score":0.8220000267028809},{"id":"https://openalex.org/keywords/strain-differences","display_name":"strain differences","score":0.5490000247955322},{"id":"https://openalex.org/keywords/lewis-rats","display_name":"Lewis rats","score":0.9259999990463257},{"id":"https://openalex.org/keywords/fischer-344-rats","display_name":"F344 rats","score":0.9909999966621399},{"id":"https://openalex.org/keywords/female-rats","display_name":"female rats","score":0.7490000128746033},{"id":"https://openalex.org/keywords/behavioral-stress-response","display_name":"behavioral stress response","score":0.43700000643730164},{"id":"https://openalex.org/keywords/automated-blood-sampling","display_name":"automated blood sampling","score":0.5019999742507935}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8510091304779053},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8503725528717041},{"id":"https://openalex.org/C2780352252","wikidata":"https://www.wikidata.org/wiki/Q422543","display_name":"Corticosterone","level":3,"score":0.8394111394882202},{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.6900544762611389},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.6755392551422119},{"id":"https://openalex.org/C2776476923","wikidata":"https://www.wikidata.org/wiki/Q7725","display_name":"Evening","level":2,"score":0.5512691736221313},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5145754218101501},{"id":"https://openalex.org/C79191276","wikidata":"https://www.wikidata.org/wiki/Q7259620","display_name":"Pulsatile flow","level":2,"score":0.5091566443443298},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.34434399008750916},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3016655445098877},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22384178638458252},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003345","descriptor_name":"Corticosterone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003346","descriptor_name":"Corticotropin-Releasing Hormone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007030","descriptor_name":"Hypothalamo-Hypophyseal System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010913","descriptor_name":"Pituitary-Adrenal System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011916","descriptor_name":"Rats, Inbred F344","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011917","descriptor_name":"Rats, Inbred Lew","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1210/endo.139.10.6238","doi":"https://doi.org/10.1210/endo.139.10.6238","is_oa":false,"landing_page_url":"https://doi.org/10.1210/endo.139.10.6238","pdf_url":null,"source":{"id":"https://openalex.org/S157527038","display_name":"Endocrinology","issn_l":"0013-7227","issn":["0013-7227","1945-7170"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology","raw_type":"journal-article"},{"id":"doi:10.1210/en.139.10.4044","doi":"https://doi.org/10.1210/en.139.10.4044","is_oa":false,"landing_page_url":"https://doi.org/10.1210/en.139.10.4044","pdf_url":null,"source":{"id":"https://openalex.org/S157527038","display_name":"Endocrinology","issn_l":"0013-7227","issn":["0013-7227","1945-7170"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology","raw_type":"journal-article"},{"id":"pmid:9751481","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9751481","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.326.8564","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.326.8564","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://endo.endojournals.org/content/139/10/4044.full.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.327.758","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.327.758","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.staff.ncl.ac.uk/c.d.ingram/Windle (1998) Endocrinology 139-4044.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.428600013256073}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W40556112","https://openalex.org/W181028834","https://openalex.org/W1936724401","https://openalex.org/W1951323992","https://openalex.org/W1969222626","https://openalex.org/W1978954584","https://openalex.org/W1982356068","https://openalex.org/W1984509885","https://openalex.org/W1988729957","https://openalex.org/W1998405496","https://openalex.org/W2000021703","https://openalex.org/W2001231789","https://openalex.org/W2003231994","https://openalex.org/W2004120547","https://openalex.org/W2005130856","https://openalex.org/W2006004036","https://openalex.org/W2008076130","https://openalex.org/W2008271123","https://openalex.org/W2009978910","https://openalex.org/W2013064775","https://openalex.org/W2015611430","https://openalex.org/W2022294881","https://openalex.org/W2023507956","https://openalex.org/W2024551842","https://openalex.org/W2027873041","https://openalex.org/W2030849325","https://openalex.org/W2033866290","https://openalex.org/W2033896439","https://openalex.org/W2034889240","https://openalex.org/W2039616793","https://openalex.org/W2042952590","https://openalex.org/W2044075990","https://openalex.org/W2049205766","https://openalex.org/W2052237528","https://openalex.org/W2055237606","https://openalex.org/W2062063610","https://openalex.org/W2064583088","https://openalex.org/W2065184114","https://openalex.org/W2073521351","https://openalex.org/W2074499459","https://openalex.org/W2088071720","https://openalex.org/W2094903580","https://openalex.org/W2104064137","https://openalex.org/W2120837287","https://openalex.org/W2125118393","https://openalex.org/W2131902751","https://openalex.org/W2137236202","https://openalex.org/W2148022513","https://openalex.org/W2156154823","https://openalex.org/W2167166930","https://openalex.org/W2167628947","https://openalex.org/W2292416077"],"related_works":["https://openalex.org/W7100562192","https://openalex.org/W2331746089","https://openalex.org/W2031996691","https://openalex.org/W2076061256","https://openalex.org/W2017928623","https://openalex.org/W2148022513","https://openalex.org/W7172363645","https://openalex.org/W2091514232","https://openalex.org/W68564744","https://openalex.org/W7100955648"],"abstract_inverted_index":{"The":[0,255],"dynamic":[1],"patterns":[2],"of":[3,10,89,184,208,327],"basal":[4,161,186],"and":[5,15,65,92,119,140,142,162,324,342],"stimulated":[6,163],"hypothalamo-pituitary-adrenal":[7],"(HPA)":[8],"activity":[9],"freely":[11],"moving":[12],"female":[13,340],"Lewis":[14,37,97,154,236,282,310,341],"Fischer":[16,85,130,202,246,291,343],"344":[17],"rats":[18,38,86,98,131,155,203],"were":[19,150],"compared":[20,301],"using":[21],"an":[22],"automated":[23],"blood-sampling":[24],"system.":[25],"Both":[26],"strains":[27,116],"showed":[28,39,103,117,132,204],"pulsatile":[29],"corticosterone":[30,112,148,231,256,285],"release":[31],"throughout":[32],"the":[33,100,147,175,179,209,215,275,281,328,333],"24":[34],"h":[35,53,73],"cycle.":[36],"clear":[40,157],"circadian":[41,105],"variation":[42],"in":[43,96,108,136,146,153,166,235,245,249,266,280,290,309,316,321,336],"both":[44,115,267,322],"pulse":[45,211,264],"frequency":[46,91],"(8.4":[47],"+/-":[48,56,68,76,223,228,298,306],"0.4":[49],"pulses":[50,58,88],"between":[51,59,71,79,160,339],"1700-2300":[52,72],"vs.":[54,74],"5.3":[55],"0.8":[57],"0500-1100":[60,80],"h;":[61,81],"P":[62,82],"<":[63,83],"0.05)":[64],"height":[66,93],"(198":[67],"27":[69],"ng/ml":[70,78],"107":[75],"14":[77],"0.05).":[84],"exhibited":[87],"similar":[90,205],"to":[94,122,258,278,332],"those":[95],"during":[99],"evening,":[101],"but":[102,238],"no":[104,197],"variation,":[106],"resulting":[107,248],"higher":[109],"mean":[110],"daily":[111],"concentrations.":[113],"Although":[114],"behavioral":[118],"HPA":[120,164,329],"responses":[121,149,206],"white":[123],"noise":[124],"stress":[125,176,189,279,337],"(10":[126],"min;":[127],"114":[128],"dB),":[129],"much":[133],"greater":[134,252,313],"increases":[135],"total":[137],"activity,":[138],"grooming,":[139],"rearings,":[141],"two":[143],"important":[144],"differences":[145,320],"observed.":[151],"First,":[152],"a":[156,168,185,192,250,271],"relationship":[158],"existed":[159],"activities,":[165],"that":[167,270],"significant":[169,198],"response":[170,217,257,277],"was":[171,261],"seen":[172],"only":[173],"when":[174],"coincided":[177],"with":[178,191,302],"rising":[180],"(secretory":[181],"active)":[182],"phase":[183,195,265],"pulse.":[187],"Noise":[188],"coinciding":[190],"falling":[193],"(nonsecretory)":[194],"elicited":[196],"response.":[199,254],"In":[200],"contrast,":[201],"regardless":[207],"underlying":[210],"phase.":[212],"Second,":[213],"after":[214],"peak":[216],"at":[218,294],"20":[219,243],"min":[220,244,296,304],"(Lewis,":[221],"237":[222],"67":[224],"ng/ml;":[225],"Fischer,":[226],"390":[227],"57":[229],"ng/ml),":[230],"levels":[232,286],"fell":[233],"rapidly":[234,289],"rats,":[237,247,292,311],"remained":[239],"maximally":[240],"elevated":[241],"for":[242],"significantly":[251],"integrated":[253],"i.v.":[259],"CRF":[260],"unaffected":[262],"by":[263],"strains,":[268],"suggesting":[269,312],"suprapituitary":[272],"mechanism":[273],"mediates":[274],"phase-dependent":[276],"strain.":[283,318],"CRF-induced":[284],"rose":[287],"more":[288],"peaking":[293],"10":[295],"(473":[297],"95":[299],"ng/ml)":[300,308],"30":[303],"(390":[305],"75":[307],"pituitary":[314,325],"sensitivity":[315],"this":[317],"Thus,":[319],"central":[323],"control":[326],"axis":[330],"contribute":[331],"strain":[334],"difference":[335],"responsiveness":[338],"rats.":[344]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
