{"id":"https://openalex.org/W1986983983","doi":"https://doi.org/10.1016/s0959-440x(99)80031-1","title":"Structural studies of the translational apparatus","display_name":"Structural studies of the translational apparatus","publication_year":1999,"publication_date":"1999-04-01","ids":{"openalex":"https://openalex.org/W1986983983","doi":"https://doi.org/10.1016/s0959-440x(99)80031-1","mag":"1986983983","pmid":"https://pubmed.ncbi.nlm.nih.gov/10322215"},"language":"en","primary_location":{"id":"doi:10.1016/s0959-440x(99)80031-1","doi":"https://doi.org/10.1016/s0959-440x(99)80031-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0959-440x(99)80031-1","pdf_url":null,"source":{"id":"https://openalex.org/S175155502","display_name":"Current Opinion in Structural Biology","issn_l":"0959-440X","issn":["0959-440X","1879-033X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Structural Biology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076801513","display_name":"Rajendra Kumar Agrawal","orcid":"https://orcid.org/0000-0001-9392-0065","observed_orcids":["https://orcid.org/0000-0001-9392-0065"]},"institutions":[{"id":"https://openalex.org/I1327163397","display_name":"State University of New York","ror":"https://ror.org/01q1z8k08","country_code":"US","type":"education","lineage":["https://openalex.org/I1327163397"]},{"id":"https://openalex.org/I1339417872","display_name":"Wadsworth Center","ror":"https://ror.org/050kf9c55","country_code":"US","type":"facility","lineage":["https://openalex.org/I1298060332","https://openalex.org/I1339417872"]},{"id":"https://openalex.org/I392282","display_name":"University at Albany, State University of New York","ror":"https://ror.org/012zs8222","country_code":"US","type":"education","lineage":["https://openalex.org/I392282"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rajendra K Agrawal","raw_affiliation_strings":["Wadsworth Center, Department of Biomedical Sciences, State University of New York at Albany, Empire State Plaza, Albany, NY 12201-0509, USA. agrawal@wadsworth.org","Wadsworth Center, Department of Biom\u00e9dical Sciences, State University of New York at Albany, Empire State Plaza, Albany, NY 12201-0509, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wadsworth Center, Department of Biomedical Sciences, State University of New York at Albany, Empire State Plaza, Albany, NY 12201-0509, USA. agrawal@wadsworth.org","institution_ids":["https://openalex.org/I1327163397","https://openalex.org/I1339417872","https://openalex.org/I392282"]},{"raw_affiliation_string":"Wadsworth Center, Department of Biom\u00e9dical Sciences, State University of New York at Albany, Empire State Plaza, Albany, NY 12201-0509, USA","institution_ids":["https://openalex.org/I1327163397","https://openalex.org/I1339417872","https://openalex.org/I392282"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042892654","display_name":"Joachim Frank","orcid":"https://orcid.org/0000-0001-5449-6943","observed_orcids":["https://orcid.org/0000-0001-5449-6943","https://orcid.org/0000-0002-2442-1112"]},"institutions":[{"id":"https://openalex.org/I1327163397","display_name":"State University of New York","ror":"https://ror.org/01q1z8k08","country_code":"US","type":"education","lineage":["https://openalex.org/I1327163397"]},{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I392282","display_name":"University at Albany, State University of New York","ror":"https://ror.org/012zs8222","country_code":"US","type":"education","lineage":["https://openalex.org/I392282"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joachim Frank","raw_affiliation_strings":["Howard Hughes Medical Institute, and Department of Biom\u00e9dical Sciences, State University of New York at Albany, Empire State Plaza, Albany, NY 12201-0509, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute, and Department of Biom\u00e9dical Sciences, State University of New York at Albany, Empire State Plaza, Albany, NY 12201-0509, USA","institution_ids":["https://openalex.org/I1327163397","https://openalex.org/I1344073410","https://openalex.org/I392282"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5042892654","https://openalex.org/A5076801513"],"corresponding_institution_ids":["https://openalex.org/I1327163397","https://openalex.org/I1339417872","https://openalex.org/I1344073410","https://openalex.org/I392282"],"apc_list":{"value":4360,"currency":"USD","value_usd":4360},"apc_paid":null,"fwci":0.7909,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.62797125,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"9","issue":"2","first_page":"215","last_page":"221"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ribosome-structure","display_name":"ribosome structure","score":0.9269999861717224},{"id":"https://openalex.org/keywords/70s-ribosome","display_name":"70S ribosome","score":0.8659999966621399},{"id":"https://openalex.org/keywords/50s-subunit","display_name":"50S subunit","score":0.8700000047683716},{"id":"https://openalex.org/keywords/80s-ribosome","display_name":"80S ribosome","score":0.9800000190734863},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.7609999775886536},{"id":"https://openalex.org/keywords/haloarcula-marismortui","display_name":"Haloarcula marismortui","score":0.9919999837875366},{"id":"https://openalex.org/keywords/yeast-ribosome","display_name":"yeast ribosome","score":0.6710000038146973},{"id":"https://openalex.org/keywords/mammalian-ribosome","display_name":"mammalian ribosome","score":0.8410000205039978},{"id":"https://openalex.org/keywords/ligand-binding","display_name":"ligand binding","score":0.6069999933242798},{"id":"https://openalex.org/keywords/protein-synthesis","display_name":"protein synthesis","score":0.5640000104904175},{"id":"https://openalex.org/keywords/x-ray-crystallography","display_name":"X-ray crystallography","score":0.8510000109672546}],"concepts":[{"id":"https://openalex.org/C88478588","wikidata":"https://www.wikidata.org/wiki/Q42244","display_name":"Ribosome","level":4,"score":0.8693900108337402},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.5704806447029114},{"id":"https://openalex.org/C129194359","wikidata":"https://www.wikidata.org/wiki/Q2636953","display_name":"Eukaryotic Ribosome","level":5,"score":0.55808424949646},{"id":"https://openalex.org/C69080955","wikidata":"https://www.wikidata.org/wiki/Q1088533","display_name":"50S","level":5,"score":0.5536928772926331},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.5392246842384338},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5149086713790894},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.5008120536804199},{"id":"https://openalex.org/C52721335","wikidata":"https://www.wikidata.org/wiki/Q3305843","display_name":"30S","level":5,"score":0.46187400817871094},{"id":"https://openalex.org/C67905577","wikidata":"https://www.wikidata.org/wiki/Q215980","display_name":"Ribosomal RNA","level":3,"score":0.4233744442462921},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35881394147872925},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.34485486149787903},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3445896804332733},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.12042757868766785},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012269","descriptor_name":"Ribosomal Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012270","descriptor_name":"Ribosomes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012335","descriptor_name":"RNA, Ribosomal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020285","descriptor_name":"Cryoelectron Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0959-440x(99)80031-1","doi":"https://doi.org/10.1016/s0959-440x(99)80031-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0959-440x(99)80031-1","pdf_url":null,"source":{"id":"https://openalex.org/S175155502","display_name":"Current Opinion in Structural Biology","issn_l":"0959-440X","issn":["0959-440X","1879-033X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Structural Biology","raw_type":"journal-article"},{"id":"pmid:10322215","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10322215","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in structural biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4921166289","display_name":"Time-resolved Cryo-EM of Short-lived States in Eukaryotic Translation","funder_award_id":"R01GM055440","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5239950330","display_name":"STRUCTURAL ANALYSIS OF MACROMOLECULAR ASSEMBLY","funder_award_id":"R37GM029169","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W143946901","https://openalex.org/W1605208286","https://openalex.org/W1810161475","https://openalex.org/W1822012546","https://openalex.org/W1844993037","https://openalex.org/W1965252702","https://openalex.org/W1965698636","https://openalex.org/W1972003375","https://openalex.org/W1981899562","https://openalex.org/W1985884969","https://openalex.org/W1991658734","https://openalex.org/W1997581772","https://openalex.org/W2000064612","https://openalex.org/W2001422120","https://openalex.org/W2001596168","https://openalex.org/W2007728632","https://openalex.org/W2008025258","https://openalex.org/W2013172601","https://openalex.org/W2014451023","https://openalex.org/W2018566214","https://openalex.org/W2021761289","https://openalex.org/W2022082484","https://openalex.org/W2023864622","https://openalex.org/W2025170604","https://openalex.org/W2026817175","https://openalex.org/W2028214064","https://openalex.org/W2031225710","https://openalex.org/W2036870792","https://openalex.org/W2038686834","https://openalex.org/W2039846261","https://openalex.org/W2043247935","https://openalex.org/W2044113516","https://openalex.org/W2061146689","https://openalex.org/W2062887711","https://openalex.org/W2066644842","https://openalex.org/W2069312320","https://openalex.org/W2070436607","https://openalex.org/W2070798707","https://openalex.org/W2071043117","https://openalex.org/W2071748696","https://openalex.org/W2085536565","https://openalex.org/W2087173180","https://openalex.org/W2095855309","https://openalex.org/W2104400477","https://openalex.org/W2131710792","https://openalex.org/W2133678661","https://openalex.org/W2136936973","https://openalex.org/W2137457846","https://openalex.org/W2143086928","https://openalex.org/W2146469890","https://openalex.org/W2152348402","https://openalex.org/W2161116298","https://openalex.org/W2170908862","https://openalex.org/W6661032103","https://openalex.org/W7073569488"],"related_works":["https://openalex.org/W2096669109","https://openalex.org/W146191986","https://openalex.org/W2163593879","https://openalex.org/W2071840045","https://openalex.org/W1973350548","https://openalex.org/W1025390094","https://openalex.org/W7095282087","https://openalex.org/W78066905","https://openalex.org/W2043862477","https://openalex.org/W2060167034"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}