{"id":"https://openalex.org/W1986807641","doi":"https://doi.org/10.1016/0006-291x(84)91435-9","title":"D-Arg2-dermorphin tetrapeptide analogs: A potent and long-lasting analgesic activity after subcutaneous administration","display_name":"D-Arg2-dermorphin tetrapeptide analogs: A potent and long-lasting analgesic activity after subcutaneous administration","publication_year":1984,"publication_date":"1984-04-01","ids":{"openalex":"https://openalex.org/W1986807641","doi":"https://doi.org/10.1016/0006-291x(84)91435-9","mag":"1986807641","pmid":"https://pubmed.ncbi.nlm.nih.gov/6712689"},"language":"en","primary_location":{"id":"doi:10.1016/0006-291x(84)91435-9","doi":"https://doi.org/10.1016/0006-291x(84)91435-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-291x(84)91435-9","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1986807641"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103416403","display_name":"Yusuke Sasaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yusuke Sasaki","raw_affiliation_strings":["Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michiko Matsui","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michiko Matsui","raw_affiliation_strings":["Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089014235","display_name":"Masumi Taguchi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Masumi Taguchi","raw_affiliation_strings":["Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100514303","display_name":"Kenji Suzuki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kenji Suzuki","raw_affiliation_strings":["Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112082492","display_name":"Shinobu Sakurada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shinobu Sakurada","raw_affiliation_strings":["Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103189730","display_name":"Takumi Sato","orcid":"https://orcid.org/0000-0001-7699-8768","observed_orcids":["https://orcid.org/0000-0001-7699-8768"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Takumi Sato","raw_affiliation_strings":["Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068482988","display_name":"Tsukasa Sakurada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tsukasa Sakurada","raw_affiliation_strings":["Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007214399","display_name":"Kensuke Kisara","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kensuke Kisara","raw_affiliation_strings":["Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tohoku College of Pharmacy, Komatsushima, Sendai 983, Japan","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":0.7851,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.62574439,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"120","issue":"1","first_page":"214","last_page":"218"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.836899995803833,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.836899995803833,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.07729999721050262,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.06880000233650208,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/opioid-analgesics","display_name":"opioid analgesics","score":0.7250000238418579},{"id":"https://openalex.org/keywords/subcutaneous-administration","display_name":"subcutaneous administration","score":0.9139999747276306},{"id":"https://openalex.org/keywords/morphine-comparison","display_name":"morphine comparison","score":0.921999990940094},{"id":"https://openalex.org/keywords/tail-flick-test","display_name":"tail-flick test","score":0.9729999899864197},{"id":"https://openalex.org/keywords/opioid-agonists","display_name":"opioid agonists","score":0.5}],"concepts":[{"id":"https://openalex.org/C2778981110","wikidata":"https://www.wikidata.org/wiki/Q1771654","display_name":"Dermorphin","level":5,"score":0.9920012950897217},{"id":"https://openalex.org/C2779564779","wikidata":"https://www.wikidata.org/wiki/Q7706647","display_name":"Tetrapeptide","level":3,"score":0.9779311418533325},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6784199476242065},{"id":"https://openalex.org/C2777389121","wikidata":"https://www.wikidata.org/wiki/Q81225","display_name":"Morphine","level":2,"score":0.6560015082359314},{"id":"https://openalex.org/C2780820201","wikidata":"https://www.wikidata.org/wiki/Q173235","display_name":"Analgesic","level":2,"score":0.6441131830215454},{"id":"https://openalex.org/C2776390293","wikidata":"https://www.wikidata.org/wiki/Q2035485","display_name":"Subcutaneous injection","level":2,"score":0.5133115649223328},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4648662209510803},{"id":"https://openalex.org/C13935069","wikidata":"https://www.wikidata.org/wiki/Q2157266","display_name":"Oligopeptide","level":3,"score":0.45740842819213867},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.43765193223953247},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.3715391457080841},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.2937755286693573},{"id":"https://openalex.org/C88016717","wikidata":"https://www.wikidata.org/wiki/Q417189","display_name":"Opioid peptide","level":4,"score":0.24017229676246643},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2373335063457489},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20341283082962036},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19529849290847778},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.1024014949798584}],"mesh":[{"descriptor_ui":"D000700","descriptor_name":"Analgesics","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007279","descriptor_name":"Injections, Subcutaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018847","descriptor_name":"Opioid Peptides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0006-291x(84)91435-9","doi":"https://doi.org/10.1016/0006-291x(84)91435-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-291x(84)91435-9","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},{"id":"pmid:6712689","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6712689","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and biophysical research communications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1963969282","https://openalex.org/W1975334707","https://openalex.org/W2007089779","https://openalex.org/W2015766640","https://openalex.org/W2016920726","https://openalex.org/W2019351891","https://openalex.org/W2040985113","https://openalex.org/W2059998958","https://openalex.org/W2079403651","https://openalex.org/W2089320192","https://openalex.org/W2134389598","https://openalex.org/W2319212396","https://openalex.org/W2328166096","https://openalex.org/W2401188729"],"related_works":["https://openalex.org/W2057324233","https://openalex.org/W2333829668","https://openalex.org/W2332005815","https://openalex.org/W2003331982","https://openalex.org/W1986258003","https://openalex.org/W3102690274","https://openalex.org/W1995816413","https://openalex.org/W2044029765","https://openalex.org/W2043406246","https://openalex.org/W2009402679"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}