{"id":"https://openalex.org/W1986794635","doi":"https://doi.org/10.1016/j.molimm.2009.05.210","title":"Proteases from the fungal allergen Aspergillus regulate airway epithelial expression of complement component C3 and its activation fragment C3A","display_name":"Proteases from the fungal allergen Aspergillus regulate airway epithelial expression of complement component C3 and its activation fragment C3A","publication_year":2009,"publication_date":"2009-08-11","ids":{"openalex":"https://openalex.org/W1986794635","doi":"https://doi.org/10.1016/j.molimm.2009.05.210","mag":"1986794635"},"language":"en","primary_location":{"id":"doi:10.1016/j.molimm.2009.05.210","doi":"https://doi.org/10.1016/j.molimm.2009.05.210","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molimm.2009.05.210","pdf_url":null,"source":{"id":"https://openalex.org/S92126311","display_name":"Molecular Immunology","issn_l":"0161-5890","issn":["0161-5890","1872-9142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Immunology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1986794635"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113718988","display_name":"\u00c9va Morschl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405281163","display_name":"Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases","ror":"https://ror.org/03z258t47","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405281163","https://openalex.org/I919571938"]},{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eva Morschl","raw_affiliation_strings":["Research Center for Immunology and Autoimmune Diseases, Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, The University of Texas Health Science Center at Houston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Immunology and Autoimmune Diseases, Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, The University of Texas Health Science Center at Houston, USA","institution_ids":["https://openalex.org/I4405281163","https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045762523","display_name":"Anne T. Bell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405281163","display_name":"Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases","ror":"https://ror.org/03z258t47","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405281163","https://openalex.org/I919571938"]},{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anne T. Bell","raw_affiliation_strings":["Research Center for Immunology and Autoimmune Diseases, Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, The University of Texas Health Science Center at Houston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Immunology and Autoimmune Diseases, Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, The University of Texas Health Science Center at Houston, USA","institution_ids":["https://openalex.org/I4405281163","https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108473799","display_name":"Paul Porter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul Porter","raw_affiliation_strings":["Departments of Medicine and Immunology, Baylor College of Medicine, Houston, TX 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Immunology, Baylor College of Medicine, Houston, TX 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077013841","display_name":"David Brian Corry","orcid":"https://orcid.org/0000-0001-9729-1016","observed_orcids":["https://orcid.org/0000-0001-9729-1016"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David B. Corry","raw_affiliation_strings":["Departments of Medicine and Immunology, Baylor College of Medicine, Houston, TX 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Immunology, Baylor College of Medicine, Houston, TX 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066652273","display_name":"Scott M. Drouin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405281163","display_name":"Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases","ror":"https://ror.org/03z258t47","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405281163","https://openalex.org/I919571938"]},{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott M. Drouin","raw_affiliation_strings":["Research Center for Immunology and Autoimmune Diseases, Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, The University of Texas Health Science Center at Houston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Immunology and Autoimmune Diseases, Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, The University of Texas Health Science Center at Houston, USA","institution_ids":["https://openalex.org/I4405281163","https://openalex.org/I919571938"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5113718988"],"corresponding_institution_ids":["https://openalex.org/I4405281163","https://openalex.org/I919571938"],"apc_list":{"value":3340,"currency":"USD","value_usd":3340},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"46","issue":"14","first_page":"2826","last_page":"2827"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.8788999915122986,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.8788999915122986,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.09000000357627869,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aspergillus","display_name":"Aspergillus","score":0.8679999709129333},{"id":"https://openalex.org/keywords/fungal-allergens","display_name":"fungal allergens","score":0.8539999723434448},{"id":"https://openalex.org/keywords/protease","display_name":"proteolytic enzymes","score":0.9169999957084656},{"id":"https://openalex.org/keywords/complement-c3","display_name":"complement C3","score":0.9120000004768372},{"id":"https://openalex.org/keywords/c3a","display_name":"C3a","score":0.8209999799728394},{"id":"https://openalex.org/keywords/airway-epithelium","display_name":"airway epithelium","score":0.8420000076293945},{"id":"https://openalex.org/keywords/complement-activation","display_name":"complement activation","score":0.8999999761581421},{"id":"https://openalex.org/keywords/allergic-airway-inflammation","display_name":"allergic airway inflammation","score":0.6119999885559082}],"concepts":[{"id":"https://openalex.org/C182220744","wikidata":"https://www.wikidata.org/wiki/Q7251226","display_name":"Proteases","level":3,"score":0.7940122485160828},{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.6728386878967285},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.635662317276001},{"id":"https://openalex.org/C2776235265","wikidata":"https://www.wikidata.org/wiki/Q18392052","display_name":"Fragment (logic)","level":2,"score":0.6061676740646362},{"id":"https://openalex.org/C112313634","wikidata":"https://www.wikidata.org/wiki/Q7886648","display_name":"Complement (music)","level":5,"score":0.5104936361312866},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4826124608516693},{"id":"https://openalex.org/C2779175654","wikidata":"https://www.wikidata.org/wiki/Q335130","display_name":"Aspergillus","level":2,"score":0.46284884214401245},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.44469690322875977},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.41357383131980896},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40043359994888306},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3742717504501343},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.23761531710624695},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1827893853187561},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.14927056431770325},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.1272428035736084},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0630139410495758},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.05705937743186951},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.0},{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.molimm.2009.05.210","doi":"https://doi.org/10.1016/j.molimm.2009.05.210","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molimm.2009.05.210","pdf_url":null,"source":{"id":"https://openalex.org/S92126311","display_name":"Molecular Immunology","issn_l":"0161-5890","issn":["0161-5890","1872-9142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Immunology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1935733700","https://openalex.org/W2167109916","https://openalex.org/W839576202","https://openalex.org/W1978482118","https://openalex.org/W2134758330","https://openalex.org/W3169165326","https://openalex.org/W2888020275","https://openalex.org/W2981719851","https://openalex.org/W2035412395"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}