{"id":"https://openalex.org/W1986554137","doi":"https://doi.org/10.1039/b807498b","title":"Metal-enhanced chemiluminescence: advanced chemiluminescence concepts for the 21st century","display_name":"Metal-enhanced chemiluminescence: advanced chemiluminescence concepts for the 21st century","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W1986554137","doi":"https://doi.org/10.1039/b807498b","mag":"1986554137","pmid":"https://pubmed.ncbi.nlm.nih.gov/19690736","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2744048"},"language":"en","primary_location":{"id":"doi:10.1039/b807498b","doi":"https://doi.org/10.1039/b807498b","is_oa":false,"landing_page_url":"https://doi.org/10.1039/b807498b","pdf_url":null,"source":{"id":"https://openalex.org/S316438","display_name":"Chemical Society Reviews","issn_l":"0306-0012","issn":["0306-0012","1460-4744"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Society Reviews","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2744048","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038160973","display_name":"Kadir Aslan","orcid":"https://orcid.org/0000-0002-7617-0175","observed_orcids":["https://orcid.org/0000-0002-7617-0175"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I4405261596","display_name":"University of Maryland Biotechnology Institute","ror":"https://ror.org/05j636y43","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405261322","https://openalex.org/I4405261596"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kadir Aslan","raw_affiliation_strings":["The Institute of Fluorescence, University of Maryland Biotechnology Institute, 701 East Pratt Street, Baltimore, MD 21202, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute of Fluorescence, University of Maryland Biotechnology Institute, 701 East Pratt Street, Baltimore, MD 21202, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I4405261596"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047713796","display_name":"Chris D. Geddes","orcid":"https://orcid.org/0000-0002-9110-6374","observed_orcids":["https://orcid.org/0000-0002-9110-6374"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I4405261596","display_name":"University of Maryland Biotechnology Institute","ror":"https://ror.org/05j636y43","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405261322","https://openalex.org/I4405261596"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Chris D. Geddes","raw_affiliation_strings":["The Institute of Fluorescence, University of Maryland Biotechnology Institute, 701 East Pratt Street, Baltimore, MD 21202, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute of Fluorescence, University of Maryland Biotechnology Institute, 701 East Pratt Street, Baltimore, MD 21202, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I4405261596"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5047713796"],"corresponding_institution_ids":["https://openalex.org/I126744593","https://openalex.org/I4405261596"],"apc_list":null,"apc_paid":null,"fwci":0.6109,"has_fulltext":true,"cited_by_count":144,"citation_normalized_percentile":{"value":0.49710145,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"38","issue":"9","first_page":"2556","last_page":"2556"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12561","display_name":"bioluminescence and chemiluminescence research","score":0.9609000086784363,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12561","display_name":"bioluminescence and chemiluminescence research","score":0.9609000086784363,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.010400000028312206,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10295","display_name":"Plasmonic and Surface Plasmon Research","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/surface-plasmons","display_name":"surface plasmons","score":0.7670000195503235},{"id":"https://openalex.org/keywords/thin-metal-films","display_name":"thin metal films","score":0.8389999866485596},{"id":"https://openalex.org/keywords/directional-emission","display_name":"directional emission","score":0.8029999732971191},{"id":"https://openalex.org/keywords/quantum-yield","display_name":"quantum yield","score":0.6110000014305115},{"id":"https://openalex.org/keywords/chemiluminescent-probes","display_name":"chemiluminescent probes","score":0.6850000023841858}],"concepts":[{"id":"https://openalex.org/C145802702","wikidata":"https://www.wikidata.org/wiki/Q2931725","display_name":"Chemiluminescence","level":2,"score":0.9927253127098083},{"id":"https://openalex.org/C10390740","wikidata":"https://www.wikidata.org/wiki/Q2282401","display_name":"Analyte","level":2,"score":0.5462623834609985},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.5155682563781738},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4962158799171448},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.49563372135162354},{"id":"https://openalex.org/C171001562","wikidata":"https://www.wikidata.org/wiki/Q2856048","display_name":"Quantum yield","level":3,"score":0.493161141872406},{"id":"https://openalex.org/C110879396","wikidata":"https://www.wikidata.org/wiki/Q58392","display_name":"Plasmon","level":2,"score":0.445356160402298},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.3704371154308319},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.34984004497528076},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2856711745262146},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.18803054094314575},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.144460529088974},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.13121235370635986},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.12268117070198059},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.06676691770553589},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D008163","descriptor_name":"Luminescent Measurements","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008670","descriptor_name":"Metals","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008872","descriptor_name":"Microwaves","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020349","descriptor_name":"Surface Plasmon Resonance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1039/b807498b","doi":"https://doi.org/10.1039/b807498b","is_oa":false,"landing_page_url":"https://doi.org/10.1039/b807498b","pdf_url":null,"source":{"id":"https://openalex.org/S316438","display_name":"Chemical Society Reviews","issn_l":"0306-0012","issn":["0306-0012","1460-4744"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Society Reviews","raw_type":"journal-article"},{"id":"pmid:19690736","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19690736","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Society reviews","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2744048","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2744048","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Chem Soc Rev","raw_type":"Text"},{"id":"pmh:oai:mdsoar.org:11603/36555","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11603/36555","pdf_url":"https://mdsoar.org/bitstreams/b63abcb1-6e47-4caf-8e30-bc770ea4cba3/download","source":{"id":"https://openalex.org/S4306402556","display_name":"Maryland Shared Open Access Repository (USMAI Consortium)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"doi:10.13016/m29pxo-tlk6","doi":"https://doi.org/10.13016/m29pxo-tlk6","is_oa":true,"landing_page_url":"https://doi.org/10.13016/m29pxo-tlk6","pdf_url":null,"source":{"id":"https://openalex.org/S4306402644","display_name":"Digital Repository at the University of Maryland (University of Maryland College Park)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I66946132","host_organization_name":"University of Maryland, College Park","host_organization_lineage":["https://openalex.org/I66946132"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2744048","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2744048","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Chem Soc Rev","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3034087429","display_name":"Ultra Fast and Sensitive Fluorescence-Based Clinical Assays","funder_award_id":"K25EB007565","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G3510673192","display_name":"Middle Atlantic Regional Center for Excellence for Biodefense and Emerging Infect","funder_award_id":"U54AI057168","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8124738567","display_name":"Plasmonic Detection of Free-Bilirubin in Neonates","funder_award_id":"R21NS055187","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G897121438","display_name":null,"funder_award_id":"AI057168","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000018249","display_name":null,"funder_award_id":"AI057168","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W70975398","https://openalex.org/W154076782","https://openalex.org/W195765165","https://openalex.org/W1963872809","https://openalex.org/W1966264250","https://openalex.org/W1966909518","https://openalex.org/W1968030229","https://openalex.org/W1973007754","https://openalex.org/W1974316749","https://openalex.org/W1981606423","https://openalex.org/W1984227511","https://openalex.org/W1993364207","https://openalex.org/W1993693788","https://openalex.org/W1995177403","https://openalex.org/W2007473771","https://openalex.org/W2012025379","https://openalex.org/W2013361812","https://openalex.org/W2032165113","https://openalex.org/W2041356602","https://openalex.org/W2045563628","https://openalex.org/W2046798780","https://openalex.org/W2047861716","https://openalex.org/W2056001141","https://openalex.org/W2056051789","https://openalex.org/W2059807868","https://openalex.org/W2062698005","https://openalex.org/W2065236128","https://openalex.org/W2070342287","https://openalex.org/W2070622052","https://openalex.org/W2078520298","https://openalex.org/W2087032356","https://openalex.org/W2092139799","https://openalex.org/W2092363897","https://openalex.org/W2099230402","https://openalex.org/W2110937353","https://openalex.org/W2121378765","https://openalex.org/W2123370853","https://openalex.org/W2126880917","https://openalex.org/W2129637092","https://openalex.org/W2133605804","https://openalex.org/W2135678218","https://openalex.org/W2151175819","https://openalex.org/W2155290351","https://openalex.org/W2161146361","https://openalex.org/W2164345719","https://openalex.org/W2164417942","https://openalex.org/W2170424911","https://openalex.org/W3131593014","https://openalex.org/W4229487420","https://openalex.org/W4249090005"],"related_works":["https://openalex.org/W2129637092","https://openalex.org/W2059807868","https://openalex.org/W1993364207","https://openalex.org/W4401693423","https://openalex.org/W2950224468","https://openalex.org/W2093386776","https://openalex.org/W3126353707","https://openalex.org/W3214097979","https://openalex.org/W2150773033","https://openalex.org/W2096550465"],"abstract_inverted_index":{"Chemiluminescent-based":[0],"detection":[1,51],"is":[2,52],"entrenched":[3],"throughout":[4],"the":[5,19,27,56,68,83,133],"biosciences":[6],"today,":[7],"such":[8],"as":[9],"in":[10],"blotting,":[11],"analyte":[12],"and":[13,16,36,89],"protein":[14],"quantification":[15],"detection.":[17],"While":[18],"biological":[20],"applications":[21],"of":[22,30,60],"chemiluminescence":[23,91,98,117],"are":[24],"forever":[25],"growing,":[26],"underlying":[28],"principles":[29],"using":[31],"a":[32,37,72],"probe,":[33],"an":[34],"oxidizer":[35],"catalyst":[38],"(biological,":[39],"organic":[40],"or":[41],"inorganic)":[42],"have":[43],"remained":[44],"mostly":[45],"unchanged":[46],"for":[47],"decades.":[48],"Subsequently,":[49],"chemiluminescence-based":[50],"fundamentally":[53,81],"limited":[54],"by":[55],"classical":[57],"photochemical":[58],"properties":[59],"reaction":[61],"yield,":[62,64],"quantum":[63],"etc.":[65],"However,":[66],"over":[67],"last":[69],"5":[70],"years,":[71],"new":[73],"technology":[74],"has":[75],"emerged":[76],"which":[77],"looks":[78],"set":[79],"to":[80],"change":[82],"way":[84],"we":[85,127],"both":[86],"think":[87],"about":[88],"use":[90],"today.":[92],"Metal":[93],"surface":[94],"plasmons":[95],"can":[96,103,113],"amplify":[97],"signatures,":[99],"while":[100],"low-power":[101],"microwaves":[102],"complete":[104],"reactions":[105],"within":[106],"seconds.":[107],"In":[108,121],"addition,":[109],"thin":[110],"metal":[111],"films":[112],"convert":[114],"spatially":[115],"isotopic":[116],"into":[118],"directional":[119],"emission.":[120],"this":[122],"forward":[123],"looking":[124],"tutorial":[125],"review,":[126],"survey":[128],"what":[129],"could":[130],"well":[131],"be":[132],"next-generation":[134],"chemiluminescent-based":[135],"technologies.":[136]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":10}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}