{"id":"https://openalex.org/W1986354397","doi":"https://doi.org/10.1152/ajpgi.00287.2004","title":"Alterations in growth hormone receptor abundance regulate growth hormone signaling in murine obstructive cholestasis","display_name":"Alterations in growth hormone receptor abundance regulate growth hormone signaling in murine obstructive cholestasis","publication_year":2004,"publication_date":"2004-12-17","ids":{"openalex":"https://openalex.org/W1986354397","doi":"https://doi.org/10.1152/ajpgi.00287.2004","mag":"1986354397","pmid":"https://pubmed.ncbi.nlm.nih.gov/15604202"},"language":"en","primary_location":{"id":"doi:10.1152/ajpgi.00287.2004","doi":"https://doi.org/10.1152/ajpgi.00287.2004","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpgi.00287.2004","pdf_url":null,"source":{"id":"https://openalex.org/S34136372","display_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","issn_l":"0193-1857","issn":["0193-1857","1522-1547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110079029","display_name":"Matthew A. Held","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew A. Held","raw_affiliation_strings":["Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090138803","display_name":"Wilfredo Cosme\u2010Blanco","orcid":"https://orcid.org/0000-0002-2764-1487","observed_orcids":["https://orcid.org/0000-0002-2764-1487"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wilfredo Cosme-Blanco","raw_affiliation_strings":["","Yale University  ;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Yale University  ;","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110107509","display_name":"Lisa M. Difedele","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa M. Difedele","raw_affiliation_strings":["","Yale University  ;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Yale University  ;","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077159023","display_name":"Erin L. Bonkowski","orcid":"https://orcid.org/0000-0003-4798-1347","observed_orcids":["https://orcid.org/0000-0003-4798-1347"]},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erin L. Bonkowski","raw_affiliation_strings":["","University of Cincinnati"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"University of Cincinnati","institution_ids":["https://openalex.org/I63135867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110612744","display_name":"Ram K. Menon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ram K. Menon","raw_affiliation_strings":["","Pediatrics - Endocrinology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Pediatrics - Endocrinology","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037750455","display_name":"Lee A. Denson","orcid":"https://orcid.org/0000-0001-8045-7198","observed_orcids":["https://orcid.org/0000-0001-8045-7198"]},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lee A. Denson","raw_affiliation_strings":["","University of Cincinnati"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"University of Cincinnati","institution_ids":["https://openalex.org/I63135867"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2371,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.80633803,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"288","issue":"5","first_page":"G986","last_page":"G993"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/growth-hormone-resistance","display_name":"growth hormone resistance","score":0.8669999837875366},{"id":"https://openalex.org/keywords/growth-hormone-receptor","display_name":"growth hormone receptor","score":0.9810000061988831},{"id":"https://openalex.org/keywords/obstructive-cholestasis","display_name":"obstructive cholestasis","score":0.984000027179718},{"id":"https://openalex.org/keywords/biliary-atresia","display_name":"biliary atresia","score":0.8629999756813049},{"id":"https://openalex.org/keywords/insulin-like-growth-factor-i","display_name":"insulin-like growth factor I","score":0.9639999866485596},{"id":"https://openalex.org/keywords/stat5-phosphorylation","display_name":"STAT5 phosphorylation","score":0.8690000176429749},{"id":"https://openalex.org/keywords/sp3","display_name":"Sp3","score":0.9039999842643738},{"id":"https://openalex.org/keywords/bile-duct-ligation","display_name":"bile duct ligation","score":0.8500000238418579},{"id":"https://openalex.org/keywords/fat-free-mass","display_name":"fat-free mass","score":0.6779999732971191},{"id":"https://openalex.org/keywords/muscle-atrophy","display_name":"muscle atrophy","score":0.6240000128746033},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9700000286102295},{"id":"https://openalex.org/keywords/cholestatic-liver-disease","display_name":"cholestatic liver disease","score":0.8080000281333923},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"skeletal muscle","score":0.6299999952316284}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8724412322044373},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8463993072509766},{"id":"https://openalex.org/C113675107","wikidata":"https://www.wikidata.org/wiki/Q2299608","display_name":"Growth hormone receptor","level":4,"score":0.8015249967575073},{"id":"https://openalex.org/C2778593092","wikidata":"https://www.wikidata.org/wiki/Q1075923","display_name":"Cholestasis","level":2,"score":0.6706855893135071},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.5367672443389893},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5249859094619751},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.2886538803577423},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24608507752418518},{"id":"https://openalex.org/C2984496839","wikidata":"https://www.wikidata.org/wiki/Q29956617","display_name":"Growth hormone","level":3,"score":0.11668476462364197},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002779","descriptor_name":"Cholestasis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002779","descriptor_name":"Cholestasis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006128","descriptor_name":"Growth","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007334","descriptor_name":"Insulin-Like Growth Factor I","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008894","descriptor_name":"Milk Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011986","descriptor_name":"Receptors, Somatotropin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013006","descriptor_name":"Growth Hormone","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015534","descriptor_name":"Trans-Activators","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015536","descriptor_name":"Down-Regulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050799","descriptor_name":"STAT5 Transcription Factor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051705","descriptor_name":"Sp3 Transcription Factor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1152/ajpgi.00287.2004","doi":"https://doi.org/10.1152/ajpgi.00287.2004","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpgi.00287.2004","pdf_url":null,"source":{"id":"https://openalex.org/S34136372","display_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","issn_l":"0193-1857","issn":["0193-1857","1522-1547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","raw_type":"journal-article"},{"id":"pmid:15604202","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15604202","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiology. Gastrointestinal and liver physiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8600000143051147}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2700038842","display_name":null,"funder_award_id":"DK49845","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G291983892","display_name":null,"funder_award_id":"DK 02700","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4438749381","display_name":null,"funder_award_id":"DK63956","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G5746996282","display_name":"Cytokine Regulation of Liver Growth Hormone Signaling","funder_award_id":"R03DK063956","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337612","display_name":"Yale Liver Center","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1753849976","https://openalex.org/W1963687456","https://openalex.org/W1965464006","https://openalex.org/W1968882057","https://openalex.org/W1972763246","https://openalex.org/W1978147791","https://openalex.org/W1980129287","https://openalex.org/W1984828633","https://openalex.org/W1995059313","https://openalex.org/W2011030679","https://openalex.org/W2024369673","https://openalex.org/W2024433060","https://openalex.org/W2027708075","https://openalex.org/W2030789027","https://openalex.org/W2044748770","https://openalex.org/W2047003170","https://openalex.org/W2047054324","https://openalex.org/W2051405987","https://openalex.org/W2052009555","https://openalex.org/W2056788640","https://openalex.org/W2057159816","https://openalex.org/W2068853602","https://openalex.org/W2078126247","https://openalex.org/W2079103715","https://openalex.org/W2080232150","https://openalex.org/W2081977719","https://openalex.org/W2083251014","https://openalex.org/W2087696726","https://openalex.org/W2090588654","https://openalex.org/W2091532311","https://openalex.org/W2091829874","https://openalex.org/W2093081515","https://openalex.org/W2101193351","https://openalex.org/W2123169375","https://openalex.org/W2140656018","https://openalex.org/W2143319273","https://openalex.org/W2143887209","https://openalex.org/W2144665452","https://openalex.org/W2152251275","https://openalex.org/W2163387755","https://openalex.org/W2166044131","https://openalex.org/W2169057757","https://openalex.org/W4255221283","https://openalex.org/W4255565763","https://openalex.org/W4390567765"],"related_works":["https://openalex.org/W4237843973","https://openalex.org/W7096917614","https://openalex.org/W2028850435","https://openalex.org/W4414296937","https://openalex.org/W2009434408","https://openalex.org/W2070856202","https://openalex.org/W1963687456","https://openalex.org/W2090588654","https://openalex.org/W2526424764","https://openalex.org/W1980129287"],"abstract_inverted_index":{"Children":[0],"with":[1,84,184,205],"cholestatic":[2,66],"liver":[3,25,61,67,174],"diseases,":[4],"in":[5,60,65,78,104,146,160,173,197,200,217,259],"particular":[6],"biliary":[7,231],"atresia,":[8],"may":[9,241,255],"develop":[10],"an":[11],"acquired":[12],"growth":[13,34,41],"hormone":[14],"(GH)":[15],"resistance.":[16],"This":[17,181],"is":[18,69,221],"characterized":[19],"by":[20],"normal":[21],"GH":[22,26,58,233,257],"secretion,":[23],"reduced":[24,31,43,75,145,185,196,206,227],"receptor":[27],"(GHR)":[28],"abundance,":[29],"and":[30,46,50,62,89,95,117,124,163,175,189,230],"circulating":[32],"insulin-like":[33],"factor":[35],"I":[36],"(IGF-I).":[37],"Consequences":[38],"include":[39],"linear":[40],"failure,":[42],"muscle":[44,64,177],"mass,":[45],"increased":[47,172],"perioperative":[48],"morbidity":[49],"mortality.":[51],"However,":[52],"the":[53,87,246],"molecular":[54],"basis":[55],"for":[56],"altered":[57],"signaling":[59,258],"skeletal":[63,176],"disease":[68],"not":[70],"known.":[71],"We":[72],"hypothesized":[73],"that":[74,250],"IGF-I":[76,125,190],"expression":[77,126,194,240,254],"obstructive":[79,219,247],"cholestasis":[80,220],"would":[81],"be":[82,242],"associated":[83,183,204],"downregulation":[85,237],"of":[86,92,97,178,226,238],"GHR":[88,193,211,239,253],"impaired":[90],"phosphorylation":[91],"signal":[93],"transducers":[94],"activators":[96],"transcription":[98],"(STAT5).":[99],"Body":[100],"composition":[101],"was":[102,144,171,182,195,203],"determined":[103],"C57BL/6J":[105],"male":[106],"mice":[107,148],"after":[108],"bile":[109],"duct":[110],"ligation":[111],"(BDL)":[112],"relative":[113,149,166],"to":[114,150,156,167,209,223,236,245],"pair-fed":[115],"(PF)":[116],"ad":[118,151],"libitum-fed":[119,152],"controls.":[120,153,169],"GHR,":[121],"STAT5,":[122],"Sp3,":[123],"and/or":[127,138],"DNA":[128],"binding":[129,208],"were":[130],"assessed":[131],"using":[132],"immunoblots,":[133],"electrophoretic":[134],"mobility":[135],"shift":[136],"assays,":[137],"real":[139],"time":[140],"RT-PCR.":[141],"Fat-free":[142],"mass":[143,162,165],"PF":[147,168],"BDL":[154,179,198],"led":[155],"a":[157,210],"further":[158],"reduction":[159],"fat":[161],"fat-free":[164],"TNF-alpha":[170],"mice.":[180],"GH-dependent":[186],"STAT5":[187],"activation":[188],"RNA":[191],"expression.":[192],"mice;":[199],"liver,":[201],"this":[202,260],"Sp3":[207],"gene":[212],"promoter":[213],"cis":[214],"element.":[215],"Wasting":[216],"murine":[218],"due":[222,235],"combined":[224],"effects":[225],"caloric":[228],"intake":[229],"obstruction.":[232],"resistance":[234],"attributed":[243],"primarily":[244],"cholestasis;":[248],"therapies":[249],"specifically":[251],"increase":[252],"restore":[256],"setting.":[261]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}