{"id":"https://openalex.org/W1986223281","doi":"https://doi.org/10.1002/dvdy.10316","title":"Three\u2010dimensional morphology of inner ear development in Xenopus laevis","display_name":"Three\u2010dimensional morphology of inner ear development in Xenopus laevis","publication_year":2003,"publication_date":"2003-05-29","ids":{"openalex":"https://openalex.org/W1986223281","doi":"https://doi.org/10.1002/dvdy.10316","mag":"1986223281","pmid":"https://pubmed.ncbi.nlm.nih.gov/12815629"},"language":"en","primary_location":{"id":"doi:10.1002/dvdy.10316","doi":"https://doi.org/10.1002/dvdy.10316","is_oa":false,"landing_page_url":"https://doi.org/10.1002/dvdy.10316","pdf_url":null,"source":{"id":"https://openalex.org/S104993753","display_name":"Developmental Dynamics","issn_l":"1058-8388","issn":["1058-8388","1097-0177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Dynamics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023574734","display_name":"Michele Miller Bever","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michele Miller Bever","raw_affiliation_strings":["Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000806148","display_name":"Ying Y. Jean","orcid":"https://orcid.org/0000-0002-1004-0108","observed_orcids":["https://orcid.org/0000-0002-1004-0108"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ying Y. Jean","raw_affiliation_strings":["Department of Biological Sciences, Purdue University, West Lafayette, Indiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Purdue University, West Lafayette, Indiana","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055156340","display_name":"Donna M. Fekete","orcid":"https://orcid.org/0000-0003-0662-0246","observed_orcids":["https://orcid.org/0000-0003-0662-0246"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Donna M. Fekete","raw_affiliation_strings":["Department of Biological Sciences, Purdue University, West Lafayette, Indiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Purdue University, West Lafayette, Indiana","institution_ids":["https://openalex.org/I219193219"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5055156340"],"corresponding_institution_ids":["https://openalex.org/I219193219"],"apc_list":{"value":4430,"currency":"USD","value_usd":4430},"apc_paid":null,"fwci":1.298,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.76370887,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"227","issue":"3","first_page":"422","last_page":"430"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.9286999702453613,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.9286999702453613,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0272000003606081,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13738","display_name":"Congenital Ear and Nasal Anomalies","score":0.021299999207258224,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inner-ear-development","display_name":"inner ear development","score":0.996999979019165},{"id":"https://openalex.org/keywords/membranous-labyrinth","display_name":"membranous labyrinth","score":0.9359999895095825},{"id":"https://openalex.org/keywords/xenopus-laevis","display_name":"Xenopus laevis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/otic-vesicle","display_name":"otic vesicle","score":0.8629999756813049},{"id":"https://openalex.org/keywords/semicircular-canals","display_name":"semicircular canals","score":0.7900000214576721},{"id":"https://openalex.org/keywords/endolymphatic-space","display_name":"endolymphatic space","score":0.8349999785423279},{"id":"https://openalex.org/keywords/three-dimensional-morphology","display_name":"three-dimensional morphology","score":0.7210000157356262},{"id":"https://openalex.org/keywords/vestibular-organs","display_name":"vestibular organs","score":0.6320000290870667},{"id":"https://openalex.org/keywords/hearing-organ","display_name":"auditory organ","score":0.9120000004768372},{"id":"https://openalex.org/keywords/tadpole-development","display_name":"tadpole development","score":0.7580000162124634}],"concepts":[{"id":"https://openalex.org/C2779535977","wikidata":"https://www.wikidata.org/wiki/Q1342298","display_name":"Xenopus","level":3,"score":0.9293457269668579},{"id":"https://openalex.org/C2778869571","wikidata":"https://www.wikidata.org/wiki/Q7108726","display_name":"Otic vesicle","level":5,"score":0.8638557195663452},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8511552214622498},{"id":"https://openalex.org/C2778500370","wikidata":"https://www.wikidata.org/wiki/Q212344","display_name":"Inner ear","level":2,"score":0.8487699031829834},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.7210829257965088},{"id":"https://openalex.org/C190041318","wikidata":"https://www.wikidata.org/wiki/Q596832","display_name":"Vestibular system","level":2,"score":0.681634247303009},{"id":"https://openalex.org/C2778311813","wikidata":"https://www.wikidata.org/wiki/Q7674671","display_name":"Tadpole (physics)","level":2,"score":0.6627082228660583},{"id":"https://openalex.org/C2778596372","wikidata":"https://www.wikidata.org/wiki/Q6593307","display_name":"Membranous labyrinth","level":3,"score":0.6332578659057617},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.45119333267211914},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.31338363885879517},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.2596759796142578},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.14699241518974304},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07833743095397949},{"id":"https://openalex.org/C81439078","wikidata":"https://www.wikidata.org/wiki/Q2304142","display_name":"In situ hybridization","level":4,"score":0.057533711194992065},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.057205915451049805},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C109214941","wikidata":"https://www.wikidata.org/wiki/Q18334","display_name":"Particle physics","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007758","descriptor_name":"Ear, Inner","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D007758","descriptor_name":"Ear, Inner","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D008675","descriptor_name":"Metamorphosis, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008953","descriptor_name":"Models, Anatomic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010037","descriptor_name":"Otolithic Membrane","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014982","descriptor_name":"Xenopus laevis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/dvdy.10316","doi":"https://doi.org/10.1002/dvdy.10316","is_oa":false,"landing_page_url":"https://doi.org/10.1002/dvdy.10316","pdf_url":null,"source":{"id":"https://openalex.org/S104993753","display_name":"Developmental Dynamics","issn_l":"1058-8388","issn":["1058-8388","1097-0177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Dynamics","raw_type":"journal-article"},{"id":"pmid:12815629","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12815629","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental dynamics : an official publication of the American Association of Anatomists","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5776691312","display_name":"PROGRAMMED CELL DEATH IN INNER EAR MORPHOGENESIS","funder_award_id":"F32DC000413","funder_id":"https://openalex.org/F4320337352","funder_display_name":"National Institute on Deafness and Other Communication Disorders"}],"funders":[{"id":"https://openalex.org/F4320337352","display_name":"National Institute on Deafness and Other Communication Disorders","ror":"https://ror.org/04mhx6838"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W30761492","https://openalex.org/W34443399","https://openalex.org/W39155963","https://openalex.org/W157193484","https://openalex.org/W570111120","https://openalex.org/W620783196","https://openalex.org/W957636845","https://openalex.org/W1484821918","https://openalex.org/W1518787232","https://openalex.org/W1555769725","https://openalex.org/W1598975690","https://openalex.org/W1608867551","https://openalex.org/W1871855518","https://openalex.org/W1890207703","https://openalex.org/W1902668062","https://openalex.org/W1970517203","https://openalex.org/W1976931512","https://openalex.org/W1979495004","https://openalex.org/W1980241872","https://openalex.org/W2000925682","https://openalex.org/W2001653494","https://openalex.org/W2001673618","https://openalex.org/W2009956304","https://openalex.org/W2012836418","https://openalex.org/W2014755422","https://openalex.org/W2017343222","https://openalex.org/W2029036708","https://openalex.org/W2036766806","https://openalex.org/W2046120901","https://openalex.org/W2046791598","https://openalex.org/W2047089209","https://openalex.org/W2053405523","https://openalex.org/W2057063345","https://openalex.org/W2075517999","https://openalex.org/W2086972110","https://openalex.org/W2091640904","https://openalex.org/W2100557347","https://openalex.org/W2121951679","https://openalex.org/W2133983394","https://openalex.org/W2143944956","https://openalex.org/W2149443501","https://openalex.org/W2153863650","https://openalex.org/W2173757756","https://openalex.org/W2258324663","https://openalex.org/W2523794187","https://openalex.org/W2914409230","https://openalex.org/W3143201166","https://openalex.org/W4254767053","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2019942860","https://openalex.org/W1893775119","https://openalex.org/W2086972110","https://openalex.org/W2036766806","https://openalex.org/W2478989188","https://openalex.org/W1976389341","https://openalex.org/W2053305953","https://openalex.org/W2370452344","https://openalex.org/W1993185984","https://openalex.org/W2012106220"],"abstract_inverted_index":{"The":[0,82],"three-dimensional":[1],"morphology":[2],"of":[3,7,31,37,51,78,100,109],"the":[4,28,41,48,52,58,79,86,97,101],"membranous":[5],"labyrinth":[6],"Xenopus":[8,32],"laevis":[9],"is":[10,75],"presented":[11],"from":[12],"embryonic":[13,42],"through":[14],"late":[15,53],"tadpole":[16],"development":[17],"(stages":[18],"28":[19,72],"to":[20,90],"52,":[21,57],"inclusive).":[22],"This":[23],"was":[24],"accomplished":[25],"by":[26],"paint-filling":[27,83],"endolymphatic":[29],"spaces":[30],"ears":[33],"at":[34],"a":[35,76,92,119],"series":[36],"stages,":[38],"beginning":[39],"with":[40,47,70],"otic":[43],"vesicle":[44,95],"and":[45,73,107,111,114],"ending":[46],"complex":[49],"ear":[50,60,94],"tadpole.":[54],"At":[55],"stage":[56,71],"inner":[59],"has":[61],"expanded":[62],"approximately":[63],"23-fold":[64],"in":[65,124],"its":[66],"anterior/posterior":[67],"dimension":[68],"compared":[69],"it":[74,115],"miniature":[77],"adult":[80],"form.":[81],"technique":[84],"illustrates":[85],"dramatic":[87],"changes":[88],"required":[89],"convert":[91],"simple":[93],"into":[96],"elaborate":[98],"form":[99],"adult,":[102],"including":[103],"semicircular":[104],"canal":[105],"formation":[106],"genesis":[108],"vestibular":[110],"auditory":[112],"organs,":[113],"can":[116],"serve":[117],"as":[118],"basis":[120],"for":[121],"phenotype":[122],"identification":[123],"experimentally":[125],"or":[126],"genetically":[127],"manipulated":[128],"ears.":[129]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}