{"id":"https://openalex.org/W1986182352","doi":"https://doi.org/10.1007/s00439-006-0147-8","title":"Ascertainment adjustment in genetic studies of ordinal traits","display_name":"Ascertainment adjustment in genetic studies of ordinal traits","publication_year":2006,"publication_date":"2006-03-09","ids":{"openalex":"https://openalex.org/W1986182352","doi":"https://doi.org/10.1007/s00439-006-0147-8","mag":"1986182352","pmid":"https://pubmed.ncbi.nlm.nih.gov/16528520"},"language":"en","primary_location":{"id":"doi:10.1007/s00439-006-0147-8","doi":"https://doi.org/10.1007/s00439-006-0147-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00439-006-0147-8","pdf_url":null,"source":{"id":"https://openalex.org/S199832308","display_name":"Human Genetics","issn_l":"0018-7348","issn":["0018-7348","0340-6717","1432-1203"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Genetics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100680619","display_name":"Rui Feng","orcid":"https://orcid.org/0000-0003-4151-7228","observed_orcids":["https://orcid.org/0000-0003-4151-7228"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rui Feng","raw_affiliation_strings":["Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA","Department of Biostatistics, University of Alabama at Birmingham, Birmingham, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Department of Biostatistics, University of Alabama at Birmingham, Birmingham, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100775543","display_name":"Heping Zhang D","orcid":"https://orcid.org/0000-0002-0688-4076","observed_orcids":["https://orcid.org/0000-0002-0688-4076","https://orcid.org/0000-0003-3608-2549"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Heping Zhang","raw_affiliation_strings":["Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, 06520-803, USA","Department of Epidemiology and Public Health, Yale University, School of Medicine, New Haven, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, 06520-803, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Epidemiology and Public Health, Yale University, School of Medicine, New Haven, USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100775543"],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":null,"fwci":0.3788,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.62227388,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"119","issue":"4","first_page":"429","last_page":"435"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ascertainment-bias","display_name":"ascertainment bias","score":0.8690000176429749},{"id":"https://openalex.org/keywords/ordinal-traits","display_name":"ordinal traits","score":0.9039999842643738},{"id":"https://openalex.org/keywords/latent-variable-modeling","display_name":"latent variable models","score":0.9129999876022339},{"id":"https://openalex.org/keywords/familial-aggregation","display_name":"familial aggregation","score":0.953000009059906},{"id":"https://openalex.org/keywords/heritability","display_name":"heritability","score":0.8989999890327454},{"id":"https://openalex.org/keywords/alcoholism","display_name":"alcoholism","score":0.8759999871253967},{"id":"https://openalex.org/keywords/comorbid-anxiety","display_name":"anxiety comorbidity","score":0.824999988079071},{"id":"https://openalex.org/keywords/high-risk-families","display_name":"high-risk families","score":0.7689999938011169},{"id":"https://openalex.org/keywords/simulation-study","display_name":"simulation study","score":0.42100000381469727}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6369604468345642},{"id":"https://openalex.org/C85461838","wikidata":"https://www.wikidata.org/wiki/Q7100785","display_name":"Ordinal data","level":2,"score":0.5856592059135437},{"id":"https://openalex.org/C47042493","wikidata":"https://www.wikidata.org/wiki/Q265799","display_name":"Human genetics","level":3,"score":0.5563240051269531},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4817793071269989},{"id":"https://openalex.org/C51167844","wikidata":"https://www.wikidata.org/wiki/Q4422623","display_name":"Latent variable","level":2,"score":0.4362598657608032},{"id":"https://openalex.org/C75917345","wikidata":"https://www.wikidata.org/wiki/Q2725298","display_name":"Sampling bias","level":3,"score":0.4132671654224396},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.39927399158477783},{"id":"https://openalex.org/C149782125","wikidata":"https://www.wikidata.org/wiki/Q160039","display_name":"Econometrics","level":1,"score":0.34028691053390503},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3174002170562744},{"id":"https://openalex.org/C129848803","wikidata":"https://www.wikidata.org/wiki/Q2564360","display_name":"Sample size determination","level":2,"score":0.2737357020378113},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.24704071879386902},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18343499302864075},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.17345395684242249},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008040","descriptor_name":"Genetic Linkage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019655","descriptor_name":"Quantitative Trait, Heritable","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00439-006-0147-8","doi":"https://doi.org/10.1007/s00439-006-0147-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00439-006-0147-8","pdf_url":null,"source":{"id":"https://openalex.org/S199832308","display_name":"Human Genetics","issn_l":"0018-7348","issn":["0018-7348","0340-6717","1432-1203"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Genetics","raw_type":"journal-article"},{"id":"pmid:16528520","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16528520","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human genetics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2991635374","display_name":"Methodological Research on Substance Use","funder_award_id":"K02DA017713","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G8471955614","display_name":"Analysis of Genomic Data for Complex Traits","funder_award_id":"R01DA016750","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"}],"funders":[{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W621715","https://openalex.org/W3492591","https://openalex.org/W29491502","https://openalex.org/W155004817","https://openalex.org/W1975737929","https://openalex.org/W1980365517","https://openalex.org/W1984369236","https://openalex.org/W1999401528","https://openalex.org/W2008179914","https://openalex.org/W2023706504","https://openalex.org/W2049633694","https://openalex.org/W2083497187","https://openalex.org/W2132042667","https://openalex.org/W2151031021","https://openalex.org/W2152173558"],"related_works":["https://openalex.org/W1971499416","https://openalex.org/W2152158299","https://openalex.org/W1907121252","https://openalex.org/W1975737929","https://openalex.org/W2034590388","https://openalex.org/W1976466685","https://openalex.org/W1980365517","https://openalex.org/W2035508428","https://openalex.org/W2083497187","https://openalex.org/W7097817297"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}