{"id":"https://openalex.org/W1986176552","doi":"https://doi.org/10.1016/s0025-6196(11)60545-4","title":"Impact of Ezetimibe on Atherosclerosis: Is the Jury Still Out?","display_name":"Impact of Ezetimibe on Atherosclerosis: Is the Jury Still Out?","publication_year":2009,"publication_date":"2009-04-01","ids":{"openalex":"https://openalex.org/W1986176552","doi":"https://doi.org/10.1016/s0025-6196(11)60545-4","mag":"1986176552","pmid":"https://pubmed.ncbi.nlm.nih.gov/19339654","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2665981"},"language":"en","primary_location":{"id":"doi:10.1016/s0025-6196(11)60545-4","doi":"https://doi.org/10.1016/s0025-6196(11)60545-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0025-6196(11)60545-4","pdf_url":null,"source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.mayoclinicproceedings.org/article/S0025619611605454/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083460733","display_name":"Firas J. Al Badarin","orcid":"https://orcid.org/0000-0003-1303-208X","observed_orcids":["https://orcid.org/0000-0003-1303-208X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Firas J. Al Badarin","raw_affiliation_strings":["Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065025844","display_name":"Iftikhar J. Kullo","orcid":"https://orcid.org/0000-0002-6524-3471","observed_orcids":["https://orcid.org/0000-0002-6524-3471"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Iftikhar J. Kullo","raw_affiliation_strings":["Cardiovascular Health Clinic, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Health Clinic, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038321413","display_name":"Stephen Louis Kopecky","orcid":"https://orcid.org/0000-0002-0506-405X","observed_orcids":["https://orcid.org/0000-0002-0506-405X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen L. Kopecky","raw_affiliation_strings":["Cardiovascular Health Clinic, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Health Clinic, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018346852","display_name":"Randal J. Thomas","orcid":"https://orcid.org/0000-0003-1448-7182","observed_orcids":["https://orcid.org/0000-0003-1448-7182"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Randal J. Thomas","raw_affiliation_strings":["Cardiovascular Health Clinic, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Health Clinic, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5018346852"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":0.9035,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.64615958,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"84","issue":"4","first_page":"353","last_page":"361"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ezetimibe","display_name":"ezetimibe","score":1.0},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/ldl-cholesterol-lowering","display_name":"LDL cholesterol lowering","score":0.6890000104904175},{"id":"https://openalex.org/keywords/statin-combination-therapy","display_name":"statin combination therapy","score":0.8299999833106995},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.671999990940094},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6990000009536743},{"id":"https://openalex.org/keywords/endothelial-function","display_name":"endothelial function","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cardiovascular-event-prevention","display_name":"cardiovascular event prevention","score":0.7400000095367432},{"id":"https://openalex.org/keywords/lipid-lowering-drugs","display_name":"lipid-lowering drugs","score":0.6499999761581421}],"concepts":[{"id":"https://openalex.org/C2778657065","wikidata":"https://www.wikidata.org/wiki/Q417997","display_name":"Ezetimibe","level":3,"score":0.9945870637893677},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9036664962768555},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.4963753819465637},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43462276458740234},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.41142284870147705},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3263234496116638}],"mesh":[{"descriptor_ui":"D000069438","descriptor_name":"Ezetimibe","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000924","descriptor_name":"Anticholesteremic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001384","descriptor_name":"Azetidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001384","descriptor_name":"Azetidines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/s0025-6196(11)60545-4","doi":"https://doi.org/10.1016/s0025-6196(11)60545-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0025-6196(11)60545-4","pdf_url":null,"source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},{"id":"doi:10.4065/84.4.353","doi":"https://doi.org/10.4065/84.4.353","is_oa":true,"landing_page_url":"https://doi.org/10.4065/84.4.353","pdf_url":"http://www.mayoclinicproceedings.org/article/S0025619611605454/pdf","source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2665981","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2665981","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clin Proc","raw_type":"Text"},{"id":"pmid:19339654","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19339654","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic proceedings","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.4065/84.4.353","doi":"https://doi.org/10.4065/84.4.353","is_oa":true,"landing_page_url":"https://doi.org/10.4065/84.4.353","pdf_url":"http://www.mayoclinicproceedings.org/article/S0025619611605454/pdf","source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1986176552.pdf","grobid_xml":"https://content.openalex.org/works/W1986176552.grobid-xml"},"referenced_works_count":85,"referenced_works":["https://openalex.org/W57851565","https://openalex.org/W93553949","https://openalex.org/W156853490","https://openalex.org/W1458263521","https://openalex.org/W1965408926","https://openalex.org/W1967516794","https://openalex.org/W1968240228","https://openalex.org/W1968676602","https://openalex.org/W1968973887","https://openalex.org/W1972926621","https://openalex.org/W1977317764","https://openalex.org/W1977429372","https://openalex.org/W1979034503","https://openalex.org/W1979599720","https://openalex.org/W1981851376","https://openalex.org/W1985258577","https://openalex.org/W1986215651","https://openalex.org/W1987507883","https://openalex.org/W1993783526","https://openalex.org/W1993966022","https://openalex.org/W1999531413","https://openalex.org/W2000050250","https://openalex.org/W2001593915","https://openalex.org/W2006115745","https://openalex.org/W2015503831","https://openalex.org/W2021422705","https://openalex.org/W2021879218","https://openalex.org/W2025321056","https://openalex.org/W2034914625","https://openalex.org/W2037251934","https://openalex.org/W2039816892","https://openalex.org/W2049092532","https://openalex.org/W2050327095","https://openalex.org/W2060479260","https://openalex.org/W2061489988","https://openalex.org/W2062693500","https://openalex.org/W2066011208","https://openalex.org/W2066383497","https://openalex.org/W2066963386","https://openalex.org/W2067231723","https://openalex.org/W2070396041","https://openalex.org/W2073693827","https://openalex.org/W2077048680","https://openalex.org/W2080203935","https://openalex.org/W2084969952","https://openalex.org/W2103825268","https://openalex.org/W2105672167","https://openalex.org/W2106384954","https://openalex.org/W2108066313","https://openalex.org/W2111385165","https://openalex.org/W2113284407","https://openalex.org/W2113295254","https://openalex.org/W2113842550","https://openalex.org/W2116416944","https://openalex.org/W2116968443","https://openalex.org/W2116999983","https://openalex.org/W2120289695","https://openalex.org/W2120491756","https://openalex.org/W2120860913","https://openalex.org/W2122146058","https://openalex.org/W2123341306","https://openalex.org/W2130249599","https://openalex.org/W2132725727","https://openalex.org/W2134068835","https://openalex.org/W2135201678","https://openalex.org/W2136964217","https://openalex.org/W2137930510","https://openalex.org/W2137983259","https://openalex.org/W2147346175","https://openalex.org/W2154095174","https://openalex.org/W2156465863","https://openalex.org/W2156593520","https://openalex.org/W2157653707","https://openalex.org/W2157794490","https://openalex.org/W2162985707","https://openalex.org/W2166131374","https://openalex.org/W2167045683","https://openalex.org/W2168876694","https://openalex.org/W2169523655","https://openalex.org/W2171546997","https://openalex.org/W2319045997","https://openalex.org/W2325048083","https://openalex.org/W3022401702","https://openalex.org/W4233806085","https://openalex.org/W4367363114"],"related_works":["https://openalex.org/W93553949","https://openalex.org/W2150093840","https://openalex.org/W2592774286","https://openalex.org/W1985867796","https://openalex.org/W1996873478","https://openalex.org/W189181430","https://openalex.org/W2058448686","https://openalex.org/W2115758193","https://openalex.org/W2238830788","https://openalex.org/W2109224891"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
