{"id":"https://openalex.org/W1986167698","doi":"https://doi.org/10.1016/s0092-8674(02)01169-8","title":"SRC-1 and TIF2 Control Energy Balance between White and Brown Adipose Tissues","display_name":"SRC-1 and TIF2 Control Energy Balance between White and Brown Adipose Tissues","publication_year":2002,"publication_date":"2002-12-01","ids":{"openalex":"https://openalex.org/W1986167698","doi":"https://doi.org/10.1016/s0092-8674(02)01169-8","mag":"1986167698","pmid":"https://pubmed.ncbi.nlm.nih.gov/12507421"},"language":"en","primary_location":{"id":"doi:10.1016/s0092-8674(02)01169-8","doi":"https://doi.org/10.1016/s0092-8674(02)01169-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0092-8674(02)01169-8","pdf_url":"http://www.cell.com/article/S0092867402011698/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0092867402011698/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068770639","display_name":"Fr\u00e9d\u00e9ric Picard","orcid":"https://orcid.org/0000-0003-4365-0743","observed_orcids":["https://orcid.org/0000-0003-4365-0743"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fr\u00e9d\u00e9ric Picard","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047505892","display_name":"Martine G\u00e9hin","orcid":"https://orcid.org/0000-0003-0780-1073","observed_orcids":["https://orcid.org/0000-0003-0780-1073"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Martine G\u00e9hin","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055079796","display_name":"Jean\u2010S\u00e9bastien Annicotte","orcid":"https://orcid.org/0000-0002-2109-4849","observed_orcids":["https://orcid.org/0000-0002-2109-4849"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-S\u00e9bastien Annicotte","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011959227","display_name":"St\u00e9phane Rocchi","orcid":"https://orcid.org/0000-0002-0943-1304","observed_orcids":["https://orcid.org/0000-0002-0943-1304"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"St\u00e9phane Rocchi","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112749977","display_name":"Marie\u2010France Champy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126578","display_name":"Ph\u00e9notypage et ing\u00e9nierie pr\u00e9cliniques des syst\u00e8mes d\u2019organismes mod\u00e8les","ror":"https://ror.org/03cjqqq10","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210126578"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie-France Champy","raw_affiliation_strings":["Institut Clinique de la Souris, G\u00e9nopole Strasbourg, 67404 Illkirch, France","ICS - Institut Clinique de la Souris (G\u00e9nopole de Strasbourg 67404 Illkirch Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Clinique de la Souris, G\u00e9nopole Strasbourg, 67404 Illkirch, France","institution_ids":["https://openalex.org/I4210126578"]},{"raw_affiliation_string":"ICS - Institut Clinique de la Souris (G\u00e9nopole de Strasbourg 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210126578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057978718","display_name":"Bert W. O\u2019Malley","orcid":"https://orcid.org/0000-0003-3332-1399","observed_orcids":["https://orcid.org/0000-0003-3332-1399"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bert W. O'Malley","raw_affiliation_strings":["Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 USA","BCM - Baylor College of Medicine (One Baylor Plaza, Houston, Texas 77030 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 USA","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"BCM - Baylor College of Medicine (One Baylor Plaza, Houston, Texas 77030 - United States)","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085761422","display_name":"Pierre Chambon","orcid":"https://orcid.org/0000-0002-7861-6046","observed_orcids":["https://orcid.org/0000-0002-7861-6046"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I4210126578","display_name":"Ph\u00e9notypage et ing\u00e9nierie pr\u00e9cliniques des syst\u00e8mes d\u2019organismes mod\u00e8les","ror":"https://ror.org/03cjqqq10","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210126578"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pierre Chambon","raw_affiliation_strings":["Institut Clinique de la Souris, G\u00e9nopole Strasbourg, 67404 Illkirch, France","Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","ICS - Institut Clinique de la Souris (G\u00e9nopole de Strasbourg 67404 Illkirch Cedex - France)","IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Clinique de la Souris, G\u00e9nopole Strasbourg, 67404 Illkirch, France","institution_ids":["https://openalex.org/I4210126578"]},{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"ICS - Institut Clinique de la Souris (G\u00e9nopole de Strasbourg 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210126578"]},{"raw_affiliation_string":"IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003154600","display_name":"Johan H. Auwerx","orcid":"https://orcid.org/0000-0002-5065-5393","observed_orcids":["https://orcid.org/0000-0002-5065-5393"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I4210126578","display_name":"Ph\u00e9notypage et ing\u00e9nierie pr\u00e9cliniques des syst\u00e8mes d\u2019organismes mod\u00e8les","ror":"https://ror.org/03cjqqq10","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210126578"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Johan Auwerx","raw_affiliation_strings":["Institut Clinique de la Souris, G\u00e9nopole Strasbourg, 67404 Illkirch, France","Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","ICS - Institut Clinique de la Souris (G\u00e9nopole de Strasbourg 67404 Illkirch Cedex - France)","IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Clinique de la Souris, G\u00e9nopole Strasbourg, 67404 Illkirch, France","institution_ids":["https://openalex.org/I4210126578"]},{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP, 67404 Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872"]},{"raw_affiliation_string":"ICS - Institut Clinique de la Souris (G\u00e9nopole de Strasbourg 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210126578"]},{"raw_affiliation_string":"IGBMC - Institut de g\u00e9n\u00e9tique et biologie mol\u00e9culaire et cellulaire (I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX - France)","institution_ids":["https://openalex.org/I4210086872"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5003154600"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210126578"],"apc_list":{"value":11400,"currency":"USD","value_usd":11400},"apc_paid":null,"fwci":14.9322,"has_fulltext":false,"cited_by_count":448,"citation_normalized_percentile":{"value":0.99508288,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"111","issue":"7","first_page":"931","last_page":"941"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/src-1","display_name":"SRC-1","score":0.9869999885559082},{"id":"https://openalex.org/keywords/tif2","display_name":"TIF2","score":0.9620000123977661},{"id":"https://openalex.org/keywords/energy-homeostasis","display_name":"energy homeostasis","score":0.8799999952316284},{"id":"https://openalex.org/keywords/white-adipose-tissue","display_name":"white adipose tissue","score":0.8930000066757202},{"id":"https://openalex.org/keywords/brown-adipose-tissue","display_name":"brown adipose tissue","score":1.0},{"id":"https://openalex.org/keywords/thermogenesis","display_name":"thermogenesis","score":0.7730000019073486},{"id":"https://openalex.org/keywords/ppargamma","display_name":"PPAR\u03b3","score":0.7979999780654907},{"id":"https://openalex.org/keywords/pgc-1alpha","display_name":"PGC-1\u03b1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.871999979019165},{"id":"https://openalex.org/keywords/energy-expenditure","display_name":"energy expenditure","score":0.906000018119812},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.9779999852180481},{"id":"https://openalex.org/keywords/fat-deposition","display_name":"fat deposition","score":0.5979999899864197}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.938141942024231},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.6093227863311768},{"id":"https://openalex.org/C56273599","wikidata":"https://www.wikidata.org/wiki/Q3122841","display_name":"White (mutation)","level":3,"score":0.5743045210838318},{"id":"https://openalex.org/C2777423268","wikidata":"https://www.wikidata.org/wiki/Q3663116","display_name":"Energy balance","level":2,"score":0.5424959659576416},{"id":"https://openalex.org/C151955695","wikidata":"https://www.wikidata.org/wiki/Q654528","display_name":"White adipose tissue","level":3,"score":0.534466564655304},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4325488209724426},{"id":"https://openalex.org/C2780642333","wikidata":"https://www.wikidata.org/wiki/Q901269","display_name":"Brown adipose tissue","level":3,"score":0.41180163621902466},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39111340045928955},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2671797573566437},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.15641698241233826},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1283935010433197},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002001","descriptor_name":"Adipose Tissue, Brown","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002001","descriptor_name":"Adipose Tissue, Brown","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008066","descriptor_name":"Lipolysis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012689","descriptor_name":"Sequence Homology, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022722","descriptor_name":"Thermogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D050356","descriptor_name":"Lipid Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051548","descriptor_name":"Histone Acetyltransferases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051958","descriptor_name":"Nuclear Receptor Coactivator 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056920","descriptor_name":"Nuclear Receptor Coactivator 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/s0092-8674(02)01169-8","doi":"https://doi.org/10.1016/s0092-8674(02)01169-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0092-8674(02)01169-8","pdf_url":"http://www.cell.com/article/S0092867402011698/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},{"id":"pmid:12507421","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12507421","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04143721v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-04143721","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cell, 2002, 111 (7), pp.931-941. ⟨10.1016/s0092-8674(02)01169-8⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:infoscience.epfl.ch:135395","doi":null,"is_oa":true,"landing_page_url":"http://infoscience.epfl.ch/record/135395","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5124864","host_organization_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","host_organization_lineage":["https://openalex.org/I5124864"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:infoscience.tind.io:135395","doi":null,"is_oa":true,"landing_page_url":"https://infoscience.epfl.ch/handle/20.500.14299/36701","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5124864","host_organization_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","host_organization_lineage":["https://openalex.org/I5124864"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"research article"}],"best_oa_location":{"id":"doi:10.1016/s0092-8674(02)01169-8","doi":"https://doi.org/10.1016/s0092-8674(02)01169-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0092-8674(02)01169-8","pdf_url":"http://www.cell.com/article/S0092867402011698/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1280468257","display_name":null,"funder_award_id":"1P01-DK59820-01","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G594869359","display_name":"Genetic and Metabolic Fingerprints of Coativators \"Program Project\"","funder_award_id":"P01DK059820","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W1986167698.pdf"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W1493268813","https://openalex.org/W1504753880","https://openalex.org/W1527827101","https://openalex.org/W1646199134","https://openalex.org/W1672804368","https://openalex.org/W1919133853","https://openalex.org/W1922855511","https://openalex.org/W1969161886","https://openalex.org/W1969437387","https://openalex.org/W1984138776","https://openalex.org/W1990224158","https://openalex.org/W1993860478","https://openalex.org/W1994489610","https://openalex.org/W1996821192","https://openalex.org/W2002519246","https://openalex.org/W2004743215","https://openalex.org/W2005615930","https://openalex.org/W2006647733","https://openalex.org/W2008632158","https://openalex.org/W2010912571","https://openalex.org/W2012155675","https://openalex.org/W2015544639","https://openalex.org/W2017130430","https://openalex.org/W2021760176","https://openalex.org/W2031386195","https://openalex.org/W2033678540","https://openalex.org/W2046566365","https://openalex.org/W2057443869","https://openalex.org/W2061619516","https://openalex.org/W2061777482","https://openalex.org/W2064956340","https://openalex.org/W2086730539","https://openalex.org/W2087351233","https://openalex.org/W2096519088","https://openalex.org/W2099438920","https://openalex.org/W2107735993","https://openalex.org/W2112832648","https://openalex.org/W2130030488","https://openalex.org/W2130093817","https://openalex.org/W2134382958","https://openalex.org/W2141686420","https://openalex.org/W2149426905","https://openalex.org/W2156362611","https://openalex.org/W2156575042","https://openalex.org/W2168247299","https://openalex.org/W2172032447","https://openalex.org/W2280600749","https://openalex.org/W2293412032","https://openalex.org/W2322518660","https://openalex.org/W2418029645","https://openalex.org/W2885709656","https://openalex.org/W6825510413"],"related_works":["https://openalex.org/W2006074160","https://openalex.org/W2017725667","https://openalex.org/W7043387403","https://openalex.org/W2095243938","https://openalex.org/W2106956546","https://openalex.org/W2531565618","https://openalex.org/W2039992465","https://openalex.org/W3034636381","https://openalex.org/W2141791765","https://openalex.org/W2021281507"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":22},{"year":2014,"cited_by_count":36},{"year":2013,"cited_by_count":30},{"year":2012,"cited_by_count":19}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}