{"id":"https://openalex.org/W1985932355","doi":"https://doi.org/10.1074/jbc.m114.603845","title":"p32 Is a Novel Target for Viral Protein ICP34.5 of Herpes Simplex Virus Type 1 and Facilitates Viral Nuclear Egress","display_name":"p32 Is a Novel Target for Viral Protein ICP34.5 of Herpes Simplex Virus Type 1 and Facilitates Viral Nuclear Egress","publication_year":2014,"publication_date":"2014-10-30","ids":{"openalex":"https://openalex.org/W1985932355","doi":"https://doi.org/10.1074/jbc.m114.603845","mag":"1985932355","pmid":"https://pubmed.ncbi.nlm.nih.gov/25355318","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4276848"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.m114.603845","doi":"https://doi.org/10.1074/jbc.m114.603845","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m114.603845","pdf_url":"http://www.jbc.org/article/S002192582057974X/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.jbc.org/article/S002192582057974X/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090302033","display_name":"Yu Wang","orcid":"https://orcid.org/0000-0001-5665-3164","observed_orcids":["https://orcid.org/0000-0001-5665-3164"]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Wang","raw_affiliation_strings":["From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102714782","display_name":"Yin Yang","orcid":"https://orcid.org/0009-0005-6855-8494","observed_orcids":["https://orcid.org/0009-0005-6855-8494"]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yin Yang","raw_affiliation_strings":["From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030651742","display_name":"Songfang Wu","orcid":"https://orcid.org/0000-0001-7464-6398","observed_orcids":["https://orcid.org/0000-0001-7464-6398"]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Songfang Wu","raw_affiliation_strings":["From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036309714","display_name":"Shuang Pan","orcid":"https://orcid.org/0000-0002-5087-3737","observed_orcids":["https://orcid.org/0000-0002-5087-3737"]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuang Pan","raw_affiliation_strings":["From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chaodong Zhou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chaodong Zhou","raw_affiliation_strings":["Department of Biochemistry, Institute for Drug Control, Tianjin 300070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Institute for Drug Control, Tianjin 300070, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055167302","display_name":"Yijie Ma","orcid":"https://orcid.org/0000-0002-8750-8354","observed_orcids":["https://orcid.org/0000-0002-8750-8354"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yijie Ma","raw_affiliation_strings":["Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois 60612, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois 60612, and","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021333610","display_name":"Yongxin Ru","orcid":"https://orcid.org/0000-0001-6304-1270","observed_orcids":["https://orcid.org/0000-0001-6304-1270"]},"institutions":[{"id":"https://openalex.org/I4210147887","display_name":"Institute of Hematology & Blood Diseases Hospital","ror":"https://ror.org/04n16t016","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147887"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongxin Ru","raw_affiliation_strings":["Department of Electron Microscopy, Institute of Hematology and Blood Diseases Hospital, Peking Union College, Tianjin 300020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electron Microscopy, Institute of Hematology and Blood Diseases Hospital, Peking Union College, Tianjin 300020, China","institution_ids":["https://openalex.org/I4210147887"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100562782","display_name":"Shuxu Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210147887","display_name":"Institute of Hematology & Blood Diseases Hospital","ror":"https://ror.org/04n16t016","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147887"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuxu Dong","raw_affiliation_strings":["Department of Electron Microscopy, Institute of Hematology and Blood Diseases Hospital, Peking Union College, Tianjin 300020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electron Microscopy, Institute of Hematology and Blood Diseases Hospital, Peking Union College, Tianjin 300020, China","institution_ids":["https://openalex.org/I4210147887"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101494989","display_name":"Bin He","orcid":"https://orcid.org/0000-0001-7385-5542","observed_orcids":["https://orcid.org/0000-0001-7385-5542"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Bin He","raw_affiliation_strings":["Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois 60612, and tshuo@uic.edu","\u00b6Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois 60612, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois 60612, and tshuo@uic.edu","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"\u00b6Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois 60612, and","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048723811","display_name":"Cuizhu Zhang","orcid":"https://orcid.org/0009-0007-6722-8180","observed_orcids":["https://orcid.org/0009-0007-6722-8180"]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Cuizhu Zhang","raw_affiliation_strings":["From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China, czz912@aliyun.com","From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China, czz912@aliyun.com","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001017107","display_name":"Youjia Cao","orcid":"https://orcid.org/0000-0003-2077-1999","observed_orcids":["https://orcid.org/0000-0003-2077-1999"]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Youjia Cao","raw_affiliation_strings":["From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China, caoyj@nankai.edu.cn","From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China, caoyj@nankai.edu.cn","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"From the Key laboratory of Microbial Functional Genomics of the Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China","institution_ids":["https://openalex.org/I205237279"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5001017107","https://openalex.org/A5048723811","https://openalex.org/A5101494989"],"corresponding_institution_ids":["https://openalex.org/I205237279","https://openalex.org/I39422238"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":4.8177,"has_fulltext":true,"cited_by_count":49,"citation_normalized_percentile":{"value":0.95586386,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"289","issue":"52","first_page":"35795","last_page":"35805"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-1","display_name":"herpes simplex virus type 1","score":0.9869999885559082},{"id":"https://openalex.org/keywords/icp34-5","display_name":"ICP34.5","score":0.9959999918937683},{"id":"https://openalex.org/keywords/p32","display_name":"p32","score":0.925000011920929},{"id":"https://openalex.org/keywords/inner-nuclear-membrane","display_name":"inner nuclear membrane","score":0.6970000267028809},{"id":"https://openalex.org/keywords/host-virus-protein-interaction","display_name":"host-virus protein interaction","score":0.8429999947547913},{"id":"https://openalex.org/keywords/viral-virulence-factors","display_name":"viral virulence factors","score":0.75}],"concepts":[{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.8489540815353394},{"id":"https://openalex.org/C94912109","wikidata":"https://www.wikidata.org/wiki/Q687194","display_name":"Nuclear lamina","level":5,"score":0.7443392276763916},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6075536012649536},{"id":"https://openalex.org/C59157529","wikidata":"https://www.wikidata.org/wiki/Q994741","display_name":"Nuclear transport","level":4,"score":0.5580278038978577},{"id":"https://openalex.org/C65871279","wikidata":"https://www.wikidata.org/wiki/Q42884945","display_name":"Inner membrane","level":3,"score":0.5383163094520569},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.5212545990943909},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5139941573143005},{"id":"https://openalex.org/C29512474","wikidata":"https://www.wikidata.org/wiki/Q16860021","display_name":"Nuclear protein","level":4,"score":0.4954146146774292},{"id":"https://openalex.org/C2777896290","wikidata":"https://www.wikidata.org/wiki/Q465608","display_name":"Nuclear membrane","level":3,"score":0.49015888571739197},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4880751371383667},{"id":"https://openalex.org/C179093185","wikidata":"https://www.wikidata.org/wiki/Q424506","display_name":"Lamin","level":3,"score":0.48689261078834534},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.48405805230140686},{"id":"https://openalex.org/C2780879997","wikidata":"https://www.wikidata.org/wiki/Q952587","display_name":"Viral protein","level":3,"score":0.4825848639011383},{"id":"https://openalex.org/C146998594","wikidata":"https://www.wikidata.org/wiki/Q7933625","display_name":"Viral tegument","level":2,"score":0.4812285900115967},{"id":"https://openalex.org/C126725582","wikidata":"https://www.wikidata.org/wiki/Q30679","display_name":"Nuclear pore","level":3,"score":0.4559417963027954},{"id":"https://openalex.org/C58475186","wikidata":"https://www.wikidata.org/wiki/Q4118894","display_name":"Viral entry","level":4,"score":0.44894763827323914},{"id":"https://openalex.org/C202878990","wikidata":"https://www.wikidata.org/wiki/Q830465","display_name":"Capsid","level":3,"score":0.41800931096076965},{"id":"https://openalex.org/C2780114586","wikidata":"https://www.wikidata.org/wiki/Q40260","display_name":"Cell nucleus","level":3,"score":0.4141859710216522},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.348501980304718},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14652201533317566},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08025479316711426},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.0},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000097682","descriptor_name":"Lamin B Receptor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D002522","descriptor_name":"Chlorocebus aethiops","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014709","descriptor_name":"Vero Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018259","descriptor_name":"Herpesvirus 1, Human","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057074","descriptor_name":"Virus Release","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057809","descriptor_name":"HEK293 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1074/jbc.m114.603845","doi":"https://doi.org/10.1074/jbc.m114.603845","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m114.603845","pdf_url":"http://www.jbc.org/article/S002192582057974X/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3661761","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4276848","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:25355318","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25355318","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4276848","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4276848/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biol Chem","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1074/jbc.m114.603845","doi":"https://doi.org/10.1074/jbc.m114.603845","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m114.603845","pdf_url":"http://www.jbc.org/article/S002192582057974X/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2950883129","display_name":"ICP34.5\u5728HSV\u8bf1\u5bfc\u6dcb\u5df4T\u7ec6\u80de\u51cb\u4ea1\u4e2d\u7684\u5206\u5b50\u673a\u5236\u7814\u7a76","funder_award_id":"81171556","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4379802052","display_name":"HSV encoded viral functions","funder_award_id":"R21AI092230","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5188208148","display_name":null,"funder_award_id":"B08011","funder_id":"https://openalex.org/F4320335785","funder_display_name":"Project 211"},{"id":"https://openalex.org/G5918436104","display_name":null,"funder_award_id":"B08011","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7192542328","display_name":"\u9e1f\u82f7\u9178\u4ea4\u6362\u56e0\u5b50Vav1\u5bf9\u9499\u4fe1\u53f7\u7684\u8c03\u63a7\u53ca\u5176\u5728T\u7ec6\u80de\u4e0e\u764c\u7ec6\u80de\u4e2d\u7684\u4f5c\u7528\u673a\u5236\u63a2\u8ba8","funder_award_id":"31370862","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320324787","display_name":"Peking University","ror":"https://ror.org/02v51f717"},{"id":"https://openalex.org/F4320326234","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334969","display_name":"Cancer Institute and Hospital, Chinese Academy of Medical Sciences","ror":"https://ror.org/03x937183"},{"id":"https://openalex.org/F4320335785","display_name":"Project 211","ror":null},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1985932355.pdf","grobid_xml":"https://content.openalex.org/works/W1985932355.grobid-xml"},"referenced_works_count":60,"referenced_works":["https://openalex.org/W1489196223","https://openalex.org/W1523693806","https://openalex.org/W1568132792","https://openalex.org/W1964969588","https://openalex.org/W1978968762","https://openalex.org/W1980477679","https://openalex.org/W1982401911","https://openalex.org/W1983813078","https://openalex.org/W1986536654","https://openalex.org/W1994614818","https://openalex.org/W2003152572","https://openalex.org/W2008542507","https://openalex.org/W2011625250","https://openalex.org/W2014190963","https://openalex.org/W2015149117","https://openalex.org/W2018535642","https://openalex.org/W2019186980","https://openalex.org/W2020520526","https://openalex.org/W2030981143","https://openalex.org/W2034700257","https://openalex.org/W2040541452","https://openalex.org/W2041303063","https://openalex.org/W2044267903","https://openalex.org/W2045707775","https://openalex.org/W2048030072","https://openalex.org/W2056952591","https://openalex.org/W2057702132","https://openalex.org/W2060922355","https://openalex.org/W2065634301","https://openalex.org/W2072681498","https://openalex.org/W2078714205","https://openalex.org/W2081021921","https://openalex.org/W2082779452","https://openalex.org/W2084942391","https://openalex.org/W2089667868","https://openalex.org/W2093256171","https://openalex.org/W2100837670","https://openalex.org/W2101919872","https://openalex.org/W2102716555","https://openalex.org/W2108583777","https://openalex.org/W2109863815","https://openalex.org/W2111368619","https://openalex.org/W2125283541","https://openalex.org/W2131617989","https://openalex.org/W2131870749","https://openalex.org/W2135433503","https://openalex.org/W2138346848","https://openalex.org/W2138395245","https://openalex.org/W2142404794","https://openalex.org/W2144026922","https://openalex.org/W2146525926","https://openalex.org/W2147881941","https://openalex.org/W2147928100","https://openalex.org/W2148750580","https://openalex.org/W2150198414","https://openalex.org/W2150840508","https://openalex.org/W2166570887","https://openalex.org/W2170689152","https://openalex.org/W2171236242","https://openalex.org/W2340807121"],"related_works":["https://openalex.org/W4389019148","https://openalex.org/W1821479442","https://openalex.org/W2519023924","https://openalex.org/W2110098549","https://openalex.org/W7143630089","https://openalex.org/W1983813078","https://openalex.org/W2550460113","https://openalex.org/W3200499403","https://openalex.org/W2111368619","https://openalex.org/W807431125"],"abstract_inverted_index":{"As":[0],"a":[1,30,49,59,66,123,197],"large":[2],"double-stranded":[3],"DNA":[4],"virus,":[5],"herpes":[6],"simplex":[7],"virus":[8],"type":[9],"1":[10],"(HSV-1)":[11],"assembles":[12],"capsids":[13],"in":[14,81,109],"the":[15,18,25,39,91,99,114,133,142,149,172],"nucleus":[16,161],"where":[17],"viral":[19,33,42,183,201,206],"particles":[20],"exit":[21],"by":[22,71,95,182],"budding":[23],"through":[24],"inner":[26,92],"nuclear":[27,93,104,127,145,150,156,189],"membrane.":[28],"Although":[29],"number":[31],"of":[32,41,55,62,103,107,116,125,144,152,174,196],"and":[34,101,138,147,191],"host":[35,52],"proteins":[36,54],"are":[37],"involved,":[38],"machinery":[40],"egress":[43,151,190],"is":[44,58,122,180],"not":[45],"well":[46],"understood.":[47],"In":[48],"search":[50],"for":[51,158,200,205],"interacting":[53],"ICP34.5,":[56,96],"which":[57,97],"virulence":[60],"factor":[61],"HSV-1,":[63],"we":[64],"identified":[65],"cellular":[67,167],"protein,":[68,168],"p32":[69,80,87,108,121,139,179],"(gC1qR/HABP1),":[70],"mass":[72],"spectrophotometer":[73],"analysis.":[74],"When":[75],"expressed,":[76],"ICP34.5":[77,137,185],"associated":[78],"with":[79],"mammalian":[82],"cells.":[83],"Upon":[84],"HSV-1":[85,126,136,153],"infection,":[86],"was":[88],"recruited":[89],"to":[90,141,171,186],"membrane":[94],"paralleled":[98],"phosphorylation":[100],"rearrangement":[102],"lamina.":[105],"Knockdown":[106],"HSV-1-infected":[110],"cells":[111],"significantly":[112],"reduced":[113],"production":[115],"cell-free":[117],"viruses,":[118],"suggesting":[119],"that":[120,132],"mediator":[124],"egress.":[128],"These":[129],"observations":[130],"suggest":[131],"interaction":[134],"between":[135],"leads":[140],"disintegration":[143],"lamina":[146,157],"facilitates":[148],"particles.HSV":[154],"disrupts":[155],"release":[159,173],"from":[160,176],"during":[162],"productive":[163],"infection.":[164],"Results":[165],"A":[166],"p32,":[169],"contributes":[170],"HSV":[175,188],"nucleus.":[177],"Conclusion":[178],"hijacked":[181],"protein":[184,202],"facilitate":[187],"growth.":[192],"Significance":[193],"The":[194],"discovery":[195],"novel":[198],"target":[199],"provides":[203],"insight":[204],"propagation.":[207]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":6}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}