{"id":"https://openalex.org/W1985778139","doi":"https://doi.org/10.1007/s100480100122","title":"APOE and APOC1 genetic polymorphisms in age-associated memory impairment","display_name":"APOE and APOC1 genetic polymorphisms in age-associated memory impairment","publication_year":2001,"publication_date":"2001-10-01","ids":{"openalex":"https://openalex.org/W1985778139","doi":"https://doi.org/10.1007/s100480100122","mag":"1985778139","pmid":"https://pubmed.ncbi.nlm.nih.gov/11714102"},"language":"en","primary_location":{"id":"doi:10.1007/s100480100122","doi":"https://doi.org/10.1007/s100480100122","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s100480100122","pdf_url":null,"source":{"id":"https://openalex.org/S185726200","display_name":"Neurogenetics","issn_l":"1364-6745","issn":["1364-6745","1364-6753"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"neurogenetics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054762575","display_name":"David Bartr\u00e9s\u2010Faz","orcid":"https://orcid.org/0000-0001-6020-4118","observed_orcids":["https://orcid.org/0000-0001-6020-4118"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Bartrés-Faz D.","raw_affiliation_strings":["Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Casanova 143, 08036 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Casanova 143, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035192499","display_name":"Imma C. Clemente","orcid":"https://orcid.org/0000-0003-0728-0925","observed_orcids":["https://orcid.org/0000-0003-0728-0925"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"I.C. Clemente","raw_affiliation_strings":["Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Casanova 143, 08036 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Casanova 143, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027053507","display_name":"Carme Junqu\u00e9","orcid":"https://orcid.org/0000-0002-6381-3063","observed_orcids":["https://orcid.org/0000-0002-6381-3063"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Junqué C.","raw_affiliation_strings":["Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Casanova 143, 08036 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Casanova 143, 08036 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016390524","display_name":"Neus Valveny","orcid":"https://orcid.org/0000-0003-1105-5018","observed_orcids":["https://orcid.org/0000-0003-1105-5018"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Valveny N.","raw_affiliation_strings":["Anthropology Unit, Department of Animal Biology, University of Barcelona, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anthropology Unit, Department of Animal Biology, University of Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110058471","display_name":"Antoni L\u00f3pez\u2010Alomar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"López-Alomar A.","raw_affiliation_strings":["Anthropology Unit, Department of Animal Biology, University of Barcelona, Barcelona, Spain,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anthropology Unit, Department of Animal Biology, University of Barcelona, Barcelona, Spain,","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003952457","display_name":"Josep S\u00e1nchez-Aldeguer","orcid":"https://orcid.org/0000-0002-5430-809X","observed_orcids":["https://orcid.org/0000-0002-5430-809X"]},"institutions":[{"id":"https://openalex.org/I123044942","display_name":"Universitat Aut\u00f2noma de Barcelona","ror":"https://ror.org/052g8jq94","country_code":"ES","type":"education","lineage":["https://openalex.org/I123044942"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Sánchez-Aldeguer J.","raw_affiliation_strings":["E.U. Gimbernat, Autonomous University of Barcelona, Barcelona, Spain,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"E.U. Gimbernat, Autonomous University of Barcelona, Barcelona, Spain,","institution_ids":["https://openalex.org/I123044942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5097453871","display_name":"A. L x F pez-Guill x E n","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"López-Guillén A.","raw_affiliation_strings":["CAP, Rambla, Sabadell, Catalonian Institute of Health, Barcelona, Spain,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAP, Rambla, Sabadell, Catalonian Institute of Health, Barcelona, Spain,","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000454872","display_name":"Pedro Moral","orcid":"https://orcid.org/0000-0001-5072-5892","observed_orcids":["https://orcid.org/0000-0001-5072-5892"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Moral P.","raw_affiliation_strings":["Anthropology Unit, Department of Animal Biology, University of Barcelona, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anthropology Unit, Department of Animal Biology, University of Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":0.9265,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.73535902,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"3","issue":"4","first_page":"215","last_page":"219"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.8446999788284302,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.8446999788284302,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.11270000040531158,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.007300000172108412,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/apolipoprotein-e","display_name":"apolipoprotein E","score":0.8569999933242798},{"id":"https://openalex.org/keywords/apoc1","display_name":"APOC1","score":1.0},{"id":"https://openalex.org/keywords/age-associated-memory-impairment","display_name":"age-associated memory impairment","score":0.8830000162124634},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.9509999752044678},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.7120000123977661},{"id":"https://openalex.org/keywords/cognitive-aging","display_name":"cognitive aging","score":0.9449999928474426},{"id":"https://openalex.org/keywords/alzheimer-s-disease-risk","display_name":"Alzheimer's disease risk","score":0.5799999833106995}],"concepts":[{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.7266690731048584},{"id":"https://openalex.org/C3018842126","wikidata":"https://www.wikidata.org/wiki/Q11072","display_name":"Memory impairment","level":3,"score":0.666034460067749},{"id":"https://openalex.org/C47042493","wikidata":"https://www.wikidata.org/wiki/Q265799","display_name":"Human genetics","level":3,"score":0.5852521061897278},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.5373623967170715},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4198923110961914},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.4141799509525299},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.40171876549720764},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.38429099321365356},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3680642545223236},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.3630351424217224},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.30317628383636475},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.25950610637664795},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2372206151485443},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1718127429485321},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.09747046232223511}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001056","descriptor_name":"Apolipoproteins C","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001057","descriptor_name":"Apolipoproteins E","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008569","descriptor_name":"Memory Disorders","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s100480100122","doi":"https://doi.org/10.1007/s100480100122","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s100480100122","pdf_url":null,"source":{"id":"https://openalex.org/S185726200","display_name":"Neurogenetics","issn_l":"1364-6745","issn":["1364-6745","1364-6753"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"neurogenetics","raw_type":"journal-article"},{"id":"pmid:11714102","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11714102","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurogenetics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W130023239","https://openalex.org/W1968968959","https://openalex.org/W1979891407","https://openalex.org/W1984468609","https://openalex.org/W1986541322","https://openalex.org/W1989259683","https://openalex.org/W1999631936","https://openalex.org/W2005126818","https://openalex.org/W2005980822","https://openalex.org/W2006472832","https://openalex.org/W2008526075","https://openalex.org/W2012355806","https://openalex.org/W2021181758","https://openalex.org/W2022477061","https://openalex.org/W2033128526","https://openalex.org/W2036362108","https://openalex.org/W2060803759","https://openalex.org/W2065697451","https://openalex.org/W2076867654","https://openalex.org/W2079488381","https://openalex.org/W2085686969","https://openalex.org/W2093415700","https://openalex.org/W2095514207","https://openalex.org/W2099905211","https://openalex.org/W2109206948","https://openalex.org/W2143285785","https://openalex.org/W2156523774","https://openalex.org/W2162527657","https://openalex.org/W2163718643","https://openalex.org/W2169787112","https://openalex.org/W2185186232","https://openalex.org/W2416367823","https://openalex.org/W3188902609"],"related_works":["https://openalex.org/W2027538248","https://openalex.org/W1979891407","https://openalex.org/W1526540789","https://openalex.org/W2156523774","https://openalex.org/W7120644314","https://openalex.org/W2980722999","https://openalex.org/W2013448179","https://openalex.org/W144585240","https://openalex.org/W2048561105","https://openalex.org/W3031612874"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}