{"id":"https://openalex.org/W1985777182","doi":"https://doi.org/10.1074/jbc.m207862200","title":"Identification of a Novel Transcription Factor, GAGATA-binding Protein, Involved in Androgen-mediated Expression of Prostate-specific Antigen","display_name":"Identification of a Novel Transcription Factor, GAGATA-binding Protein, Involved in Androgen-mediated Expression of Prostate-specific Antigen","publication_year":2003,"publication_date":"2003-08-01","ids":{"openalex":"https://openalex.org/W1985777182","doi":"https://doi.org/10.1074/jbc.m207862200","mag":"1985777182","pmid":"https://pubmed.ncbi.nlm.nih.gov/12782640"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.m207862200","doi":"https://doi.org/10.1074/jbc.m207862200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m207862200","pdf_url":"http://www.jbc.org/article/S002192582084054X/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.jbc.org/article/S002192582084054X/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001965208","display_name":"Chihuei Wang","orcid":"https://orcid.org/0000-0002-4948-4662","observed_orcids":["https://orcid.org/0000-0002-4948-4662"]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Chihuei Wang","raw_affiliation_strings":["Orthopedic Research Center and Department of Biology, Kaohsiung Medical University, Kaohsiung 807, Taiwan. chwang@kmu.edu.tw","Orthopedic Research Center and Department of Biology, Kaohsiung Medical University, Kaohsiung 807, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopedic Research Center and Department of Biology, Kaohsiung Medical University, Kaohsiung 807, Taiwan. chwang@kmu.edu.tw","institution_ids":["https://openalex.org/I152743029"]},{"raw_affiliation_string":"Orthopedic Research Center and Department of Biology, Kaohsiung Medical University, Kaohsiung 807, Taiwan","institution_ids":["https://openalex.org/I152743029"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021934968","display_name":"Fan Yeung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fan Yeung","raw_affiliation_strings":["Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018642124","display_name":"Po-Chun Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Po-Chun Liu","raw_affiliation_strings":["Orthopedic Research Center and Department of Biology, Kaohsiung Medical University, Kaohsiung 807, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopedic Research Center and Department of Biology, Kaohsiung Medical University, Kaohsiung 807, Taiwan","institution_ids":["https://openalex.org/I152743029"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055963089","display_name":"Ricardo M. Attar","orcid":"https://orcid.org/0000-0002-6942-8019","observed_orcids":["https://orcid.org/0000-0002-6942-8019"]},"institutions":[{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ricardo M. Attar","raw_affiliation_strings":["Department of Oncology, Bristol-Myers Squibb Co., Lawrenceville, New Jersey 08543"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Bristol-Myers Squibb Co., Lawrenceville, New Jersey 08543","institution_ids":["https://openalex.org/I4210091812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067917259","display_name":"Jieping Geng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jieping Geng","raw_affiliation_strings":["Department of Oncology, Bristol-Myers Squibb Co., Lawrenceville, New Jersey 08543"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Bristol-Myers Squibb Co., Lawrenceville, New Jersey 08543","institution_ids":["https://openalex.org/I4210091812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010686592","display_name":"Leland W.K. Chung","orcid":"https://orcid.org/0000-0003-0072-6939","observed_orcids":["https://orcid.org/0000-0003-0072-6939","https://orcid.org/0000-0001-9445-3569"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leland W.K. Chung","raw_affiliation_strings":["Department of Urology and Winship Cancer Institute, Emory University, Atlanta, Georgia 30322"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology and Winship Cancer Institute, Emory University, Atlanta, Georgia 30322","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040094376","display_name":"Marco M. Gottardis","orcid":"https://orcid.org/0000-0003-2280-8708","observed_orcids":["https://orcid.org/0000-0003-2280-8708"]},"institutions":[{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marco Gottardis","raw_affiliation_strings":["Department of Oncology, Bristol-Myers Squibb Co., Lawrenceville, New Jersey 08543"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Bristol-Myers Squibb Co., Lawrenceville, New Jersey 08543","institution_ids":["https://openalex.org/I4210091812"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111365848","display_name":"Chinghai H. Kao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Chinghai Kao","raw_affiliation_strings":["Department of Urology, University of Indiana, Indianapolis, Indiana 46202"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, University of Indiana, Indianapolis, Indiana 46202","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5001965208","https://openalex.org/A5111365848"],"corresponding_institution_ids":["https://openalex.org/I152743029"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":2.7014,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.89191673,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"278","issue":"34","first_page":"32423","last_page":"32430"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-specific-antigen","display_name":"prostate-specific antigen","score":0.9259999990463257},{"id":"https://openalex.org/keywords/androgen-receptor","display_name":"androgen receptor","score":0.871999979019165},{"id":"https://openalex.org/keywords/androgen-responsive-element","display_name":"androgen-responsive element","score":0.8009999990463257},{"id":"https://openalex.org/keywords/psa-promoter","display_name":"PSA promoter","score":0.6230000257492065},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.7900000214576721},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.6990000009536743},{"id":"https://openalex.org/keywords/transcription-factor-binding","display_name":"transcription factor binding","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C111936080","wikidata":"https://www.wikidata.org/wiki/Q913367","display_name":"Enhancer","level":4,"score":0.7482707500457764},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.6536957621574402},{"id":"https://openalex.org/C2781406297","wikidata":"https://www.wikidata.org/wiki/Q409450","display_name":"Prostate-specific antigen","level":4,"score":0.6295588612556458},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.6195724010467529},{"id":"https://openalex.org/C61367390","wikidata":"https://www.wikidata.org/wiki/Q416601","display_name":"Androgen receptor","level":4,"score":0.6014347076416016},{"id":"https://openalex.org/C183978625","wikidata":"https://www.wikidata.org/wiki/Q903596","display_name":"Electrophoretic mobility shift assay","level":4,"score":0.5948944091796875},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5341281890869141},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5113348364830017},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.45761269330978394},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.45550987124443054},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.41756486892700195},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3317135274410248},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.24941760301589966},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.22437044978141785},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2133743166923523},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2078191637992859},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11310699582099915},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.08633548021316528}],"mesh":[{"descriptor_ui":"D000728","descriptor_name":"Androgens","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011944","descriptor_name":"Receptors, Androgen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017430","descriptor_name":"Prostate-Specific Antigen","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017430","descriptor_name":"Prostate-Specific Antigen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D024202","descriptor_name":"Electrophoretic Mobility Shift Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1074/jbc.m207862200","doi":"https://doi.org/10.1074/jbc.m207862200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m207862200","pdf_url":"http://www.jbc.org/article/S002192582084054X/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:12782640","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12782640","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.m207862200","doi":"https://doi.org/10.1074/jbc.m207862200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m207862200","pdf_url":"http://www.jbc.org/article/S002192582084054X/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.7400000095367432,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2425109958","display_name":null,"funder_award_id":"CA74042","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320321040","display_name":"National Science Council","ror":"https://ror.org/02kv4zf79"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1985777182.pdf","grobid_xml":"https://content.openalex.org/works/W1985777182.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W94704893","https://openalex.org/W1577509897","https://openalex.org/W1588136567","https://openalex.org/W1602183952","https://openalex.org/W1629044468","https://openalex.org/W1837186493","https://openalex.org/W1891260587","https://openalex.org/W1973361095","https://openalex.org/W1987323136","https://openalex.org/W1989968124","https://openalex.org/W2000846615","https://openalex.org/W2000851169","https://openalex.org/W2002700673","https://openalex.org/W2007899417","https://openalex.org/W2023396505","https://openalex.org/W2043236550","https://openalex.org/W2043353211","https://openalex.org/W2043789254","https://openalex.org/W2053234324","https://openalex.org/W2069697845","https://openalex.org/W2079768382","https://openalex.org/W2080795487","https://openalex.org/W2080911219","https://openalex.org/W2084829629","https://openalex.org/W2085732523","https://openalex.org/W2087403436","https://openalex.org/W2103659378","https://openalex.org/W2116608195","https://openalex.org/W2144899441","https://openalex.org/W2748101318","https://openalex.org/W4252044604"],"related_works":["https://openalex.org/W2085732523","https://openalex.org/W7100995339","https://openalex.org/W2162612481","https://openalex.org/W2026615306","https://openalex.org/W2082413843","https://openalex.org/W2038672947","https://openalex.org/W101004691","https://openalex.org/W2023396505","https://openalex.org/W2103201026","https://openalex.org/W2145772312"],"abstract_inverted_index":{"Prostate-specific":[0],"antigen":[1],"(PSA)":[2],"is":[3,19,87,181],"the":[4,9,38,63,73,78,90,113,117,130,140,145,150,159,168,195,207,214],"most":[5],"valuable":[6],"marker":[7],"for":[8,213],"evaluation":[10],"of":[11,17,45,62,135,149,194,206],"prostate":[12,119],"cancer":[13,120],"progression.":[14],"The":[15,42,133],"expression":[16],"PSA":[18,40,48,79,208],"controlled":[20],"by":[21,99],"androgen":[22],"receptor":[23],"(AR)":[24],"through":[25,187],"its":[26],"binding":[27,171,193,197],"to":[28,72,96,201,218],"androgen-response":[29],"elements":[30],"(AREs).":[31],"Several":[32],"AREs":[33,75],"have":[34],"been":[35],"identified":[36,76,166],"within":[37],"5.8-kb":[39,47],"promoter.":[41],"main":[43],"activity":[44,148],"this":[46],"promoter":[49],"resides":[50],"in":[51,70,77,116,139,184],"a":[52,108,162],"455-bp":[53],"enhancer":[54,80,151,209],"core":[55,210],"region":[56,91],"located":[57,88],"about":[58],"4":[59],"kb":[60],"upstream":[61],"TATA":[64],"box.":[65],"Our":[66],"study":[67],"suggests":[68],"that":[69,107,125,179,192],"addition":[71],"four":[74],"core,":[81],"another":[82],"regulatory":[83],"element":[84],"(GAGATA),":[85],"which":[86],"at":[89],"designated":[92],"PSA3.1,":[93],"also":[94],"contributes":[95],"transcriptional":[97,110,147,216],"regulation":[98],"androgens.":[100,219],"Furthermore,":[101],"electrophoretic":[102],"mobility":[103],"shift":[104],"assay":[105,177],"revealed":[106],"putative":[109,169],"factor":[111,127,198],"bound":[112,129],"GAGATA":[114,126,141,170,196,202],"sequence":[115,142],"PSA-producing":[118],"cell.":[121],"Further":[122],"studies":[123],"demonstrated":[124],"preferentially":[128],"(G/C)(A/C/T)GATA":[131],"sequence.":[132],"replacement":[134],"ATA":[136],"with":[137],"GGG":[138],"completely":[143],"eliminated":[144],"androgen-mediated":[146,185],"core.":[152],"By":[153],"using":[154],"DNA-coupled":[155],"magnetic":[156],"beads":[157],"and":[158,174,199,203],"Southwestern":[160],"method,":[161],"56-60-kDa":[163],"protein":[164],"was":[165],"as":[167],"factor.":[172],"EMSA":[173],"Western":[175],"blotting":[176],"suggested":[178],"AR":[180,200],"not":[182],"involved":[183],"activation":[186],"PSA3.1.":[188],"Therefore,":[189],"we":[190],"propose":[191],"AREs,":[204],"respectively,":[205],"are":[211],"required":[212],"maximum":[215],"response":[217]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}