{"id":"https://openalex.org/W1985759436","doi":"https://doi.org/10.1016/0198-8859(92)90052-o","title":"T-cell receptor V\u03b2 selectivity in T-cell clones alloreactive to HLA-Dw14","display_name":"T-cell receptor V\u03b2 selectivity in T-cell clones alloreactive to HLA-Dw14","publication_year":1992,"publication_date":"1992-01-01","ids":{"openalex":"https://openalex.org/W1985759436","doi":"https://doi.org/10.1016/0198-8859(92)90052-o","mag":"1985759436","pmid":"https://pubmed.ncbi.nlm.nih.gov/1532170"},"language":"en","primary_location":{"id":"doi:10.1016/0198-8859(92)90052-o","doi":"https://doi.org/10.1016/0198-8859(92)90052-o","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0198-8859(92)90052-o","pdf_url":null,"source":{"id":"https://openalex.org/S6860681","display_name":"Human Immunology","issn_l":"0198-8859","issn":["0198-8859","1879-1166"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Katsuo Yamanaka","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katsuo Yamanaka","raw_affiliation_strings":["Virginia Mason Research Center, Seattle, Washington 98101"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virginia Mason Research Center, Seattle, Washington 98101","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090475940","display_name":"William W. Kwok","orcid":"https://orcid.org/0000-0003-4843-4599","observed_orcids":["https://orcid.org/0000-0003-4843-4599"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William W. Kwok","raw_affiliation_strings":["From the Virginia Mason Research Center, Seattle, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Virginia Mason Research Center, Seattle, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110162493","display_name":"Eric Mickelson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric M. Mickelson","raw_affiliation_strings":["The Fred Hutchinson Cancer Research Center, Seattle, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Fred Hutchinson Cancer Research Center, Seattle, Washington, USA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070155625","display_name":"Susan Masewicz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Masewicz","raw_affiliation_strings":["The Fred Hutchinson Cancer Research Center, Seattle, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Fred Hutchinson Cancer Research Center, Seattle, Washington, USA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038423187","display_name":"Gerald T. Nepom","orcid":"https://orcid.org/0000-0002-8063-1464","observed_orcids":["https://orcid.org/0000-0002-8063-1464"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gerald T. Nepom","raw_affiliation_strings":["From the Virginia Mason Research Center, Seattle, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Virginia Mason Research Center, Seattle, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":null,"fwci":0.9652,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.74623942,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"33","issue":"1","first_page":"57","last_page":"64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tcr-beta-chain","display_name":"T cell receptor beta chain","score":0.9049999713897705},{"id":"https://openalex.org/keywords/hla-dr4","display_name":"HLA-DR4","score":0.765999972820282},{"id":"https://openalex.org/keywords/hla-dw4","display_name":"HLA-Dw4","score":0.9480000138282776},{"id":"https://openalex.org/keywords/alloreactive-t-cell-clones","display_name":"alloreactive T cell clones","score":0.8450000286102295},{"id":"https://openalex.org/keywords/allospecificity","display_name":"allospecificity","score":0.8370000123977661},{"id":"https://openalex.org/keywords/tcr-gene-usage","display_name":"TCR gene usage","score":0.7269999980926514},{"id":"https://openalex.org/keywords/mixed-lymphocyte-reaction","display_name":"mixed lymphocyte reaction","score":0.7360000014305115}],"concepts":[{"id":"https://openalex.org/C19317047","wikidata":"https://www.wikidata.org/wiki/Q412037","display_name":"T-cell receptor","level":4,"score":0.795002818107605},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6963163614273071},{"id":"https://openalex.org/C200315206","wikidata":"https://www.wikidata.org/wiki/Q4733146","display_name":"Allorecognition","level":4,"score":0.6947018504142761},{"id":"https://openalex.org/C81089528","wikidata":"https://www.wikidata.org/wiki/Q5134986","display_name":"clone (Java method)","level":3,"score":0.649970531463623},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5510674715042114},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.5354084968566895},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5046957731246948},{"id":"https://openalex.org/C2776174256","wikidata":"https://www.wikidata.org/wiki/Q830842","display_name":"BETA (programming language)","level":2,"score":0.4789469838142395},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.46682021021842957},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4553123712539673},{"id":"https://openalex.org/C956191","wikidata":"https://www.wikidata.org/wiki/Q930144","display_name":"Polyclonal antibodies","level":3,"score":0.4255574345588684},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.42243343591690063},{"id":"https://openalex.org/C187882448","wikidata":"https://www.wikidata.org/wiki/Q283478","display_name":"Complementary DNA","level":3,"score":0.41926640272140503},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.2934378981590271},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.2550373673439026},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.09600484371185303},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002999","descriptor_name":"Clone Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D005784","descriptor_name":"Gene Amplification","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006681","descriptor_name":"HLA-D Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006681","descriptor_name":"HLA-D Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015152","descriptor_name":"Blotting, Northern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016693","descriptor_name":"Receptors, Antigen, T-Cell, alpha-beta","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016693","descriptor_name":"Receptors, Antigen, T-Cell, alpha-beta","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0198-8859(92)90052-o","doi":"https://doi.org/10.1016/0198-8859(92)90052-o","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0198-8859(92)90052-o","pdf_url":null,"source":{"id":"https://openalex.org/S6860681","display_name":"Human Immunology","issn_l":"0198-8859","issn":["0198-8859","1879-1166"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Immunology","raw_type":"journal-article"},{"id":"pmid:1532170","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1532170","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G392172342","display_name":null,"funder_award_id":"AR 37296","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G8170033159","display_name":"HLA Susceptibility Genes in Rheumatoid Arthritis","funder_award_id":"R01AR037296","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1579000294","https://openalex.org/W1964561330","https://openalex.org/W1967524558","https://openalex.org/W1983323502","https://openalex.org/W2015865604","https://openalex.org/W2018023050","https://openalex.org/W2021673452","https://openalex.org/W2031011895","https://openalex.org/W2035757181","https://openalex.org/W2037184580","https://openalex.org/W2042371846","https://openalex.org/W2053613574","https://openalex.org/W2068530163","https://openalex.org/W2080824017","https://openalex.org/W2093599503","https://openalex.org/W2124626123","https://openalex.org/W2130709219","https://openalex.org/W2134812217","https://openalex.org/W2140443312","https://openalex.org/W2154350567","https://openalex.org/W2160037356","https://openalex.org/W4229743643","https://openalex.org/W4294216491","https://openalex.org/W6659965374","https://openalex.org/W6663601495"],"related_works":["https://openalex.org/W1906951031","https://openalex.org/W2087603211","https://openalex.org/W2058255412","https://openalex.org/W2050097454","https://openalex.org/W1975535600","https://openalex.org/W2115025752","https://openalex.org/W1562295473","https://openalex.org/W2022846020","https://openalex.org/W2054803385","https://openalex.org/W2154350567"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}