{"id":"https://openalex.org/W1985752907","doi":"https://doi.org/10.1088/0031-9155/59/2/327","title":"Dynamic electron arc radiotherapy (DEAR): a feasibility study","display_name":"Dynamic electron arc radiotherapy (DEAR): a feasibility study","publication_year":2013,"publication_date":"2013-12-19","ids":{"openalex":"https://openalex.org/W1985752907","doi":"https://doi.org/10.1088/0031-9155/59/2/327","mag":"1985752907","pmid":"https://pubmed.ncbi.nlm.nih.gov/24351857"},"language":"en","primary_location":{"id":"doi:10.1088/0031-9155/59/2/327","doi":"https://doi.org/10.1088/0031-9155/59/2/327","is_oa":true,"landing_page_url":"https://doi.org/10.1088/0031-9155/59/2/327","pdf_url":"https://iopscience.iop.org/article/10.1088/0031-9155/59/2/327/pdf","source":{"id":"https://openalex.org/S20241394","display_name":"Physics in Medicine and Biology","issn_l":"0031-9155","issn":["0031-9155","1361-6560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physics in Medicine and Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://iopscience.iop.org/article/10.1088/0031-9155/59/2/327/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069207760","display_name":"Anna Rodrigues","orcid":"https://orcid.org/0000-0003-1843-0415","observed_orcids":["https://orcid.org/0000-0003-1843-0415"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anna Rodrigues","raw_affiliation_strings":["Medical Physics Graduate Program, Duke University Medical Center, Durham, NC 27705, USA. Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","Medical Physics Graduate Program, Duke University Medical Center, Durham, NC 27705, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Physics Graduate Program, Duke University Medical Center, Durham, NC 27705, USA. Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Medical Physics Graduate Program, Duke University Medical Center, Durham, NC 27705, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100651695","display_name":"F.-F. Yin","orcid":"https://orcid.org/0000-0002-2025-4740","observed_orcids":["https://orcid.org/0000-0002-2025-4740"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fang-Fang Yin","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","Medical Physics Graduate Program, Duke University Medical Center, Durham, NC 27705, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Medical Physics Graduate Program, Duke University Medical Center, Durham, NC 27705, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069570157","display_name":"Qiuwen Wu","orcid":"https://orcid.org/0000-0003-0748-7280","observed_orcids":["https://orcid.org/0000-0003-0748-7280"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Qiuwen Wu","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","Medical Physics Graduate Program, Duke University Medical Center, Durham, NC 27705, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Medical Physics Graduate Program, Duke University Medical Center, Durham, NC 27705, USA","institution_ids":["https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5069570157"],"corresponding_institution_ids":["https://openalex.org/I4210126298"],"apc_list":{"value":3325,"currency":"USD","value_usd":3325},"apc_paid":null,"fwci":1.6502,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.80920944,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"59","issue":"2","first_page":"327","last_page":"345"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10844","display_name":"Radiation Dose and Imaging","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gantry-rotation","display_name":"gantry rotation","score":0.9210000038146973},{"id":"https://openalex.org/keywords/dose-rate-modulation","display_name":"dose rate modulation","score":0.9950000047683716},{"id":"https://openalex.org/keywords/dose-distribution","display_name":"dose distribution","score":0.5379999876022339},{"id":"https://openalex.org/keywords/penumbra","display_name":"penumbra","score":0.7490000128746033},{"id":"https://openalex.org/keywords/dose-uniformity","display_name":"dose homogeneity","score":0.7680000066757202},{"id":"https://openalex.org/keywords/truebeam-linac","display_name":"TrueBeam linac","score":0.7749999761581421},{"id":"https://openalex.org/keywords/superficial-tumors","display_name":"superficial tumors","score":0.4860000014305115}],"concepts":[{"id":"https://openalex.org/C2780271382","wikidata":"https://www.wikidata.org/wiki/Q4993917","display_name":"Truebeam","level":4,"score":0.8265134692192078},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.5564000606536865},{"id":"https://openalex.org/C147120987","wikidata":"https://www.wikidata.org/wiki/Q2225","display_name":"Electron","level":2,"score":0.49621301889419556},{"id":"https://openalex.org/C180048950","wikidata":"https://www.wikidata.org/wiki/Q836828","display_name":"Linear particle accelerator","level":3,"score":0.49253949522972107},{"id":"https://openalex.org/C2780577055","wikidata":"https://www.wikidata.org/wiki/Q2069532","display_name":"Penumbra","level":3,"score":0.4890151917934418},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.4828915596008301},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4406163990497589},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.4313177466392517},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3943175673484802},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3235816955566406},{"id":"https://openalex.org/C168834538","wikidata":"https://www.wikidata.org/wiki/Q3705329","display_name":"Beam (structure)","level":2,"score":0.25126802921295166},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2212851345539093},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.14797624945640564},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.09048011898994446},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.0},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D005240","descriptor_name":"Feasibility Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010315","descriptor_name":"Particle Accelerators","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011874","descriptor_name":"Radiometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011879","descriptor_name":"Radiotherapy Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020266","descriptor_name":"Radiotherapy, Conformal","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D020266","descriptor_name":"Radiotherapy, Conformal","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1088/0031-9155/59/2/327","doi":"https://doi.org/10.1088/0031-9155/59/2/327","is_oa":true,"landing_page_url":"https://doi.org/10.1088/0031-9155/59/2/327","pdf_url":"https://iopscience.iop.org/article/10.1088/0031-9155/59/2/327/pdf","source":{"id":"https://openalex.org/S20241394","display_name":"Physics in Medicine and Biology","issn_l":"0031-9155","issn":["0031-9155","1361-6560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physics in Medicine and Biology","raw_type":"journal-article"},{"id":"pmid:24351857","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24351857","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physics in medicine and biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1088/0031-9155/59/2/327","doi":"https://doi.org/10.1088/0031-9155/59/2/327","is_oa":true,"landing_page_url":"https://doi.org/10.1088/0031-9155/59/2/327","pdf_url":"https://iopscience.iop.org/article/10.1088/0031-9155/59/2/327/pdf","source":{"id":"https://openalex.org/S20241394","display_name":"Physics in Medicine and Biology","issn_l":"0031-9155","issn":["0031-9155","1361-6560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physics in Medicine and Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.723800003528595,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.5600000023841858,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1985752907.pdf","grobid_xml":"https://content.openalex.org/works/W1985752907.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W106304874","https://openalex.org/W1968704148","https://openalex.org/W1977479214","https://openalex.org/W1978217978","https://openalex.org/W1978716186","https://openalex.org/W1979767755","https://openalex.org/W1983273276","https://openalex.org/W1983758590","https://openalex.org/W1992654860","https://openalex.org/W2005253624","https://openalex.org/W2008265395","https://openalex.org/W2008410918","https://openalex.org/W2009123901","https://openalex.org/W2010962051","https://openalex.org/W2011285164","https://openalex.org/W2018065849","https://openalex.org/W2018632599","https://openalex.org/W2024677092","https://openalex.org/W2025402333","https://openalex.org/W2028616601","https://openalex.org/W2030399884","https://openalex.org/W2031988239","https://openalex.org/W2038008306","https://openalex.org/W2040145532","https://openalex.org/W2040624787","https://openalex.org/W2045073901","https://openalex.org/W2049643504","https://openalex.org/W2050633774","https://openalex.org/W2056837760","https://openalex.org/W2058114693","https://openalex.org/W2059108666","https://openalex.org/W2060231071","https://openalex.org/W2061772583","https://openalex.org/W2063773281","https://openalex.org/W2064930554","https://openalex.org/W2068617023","https://openalex.org/W2080419699","https://openalex.org/W2081478948","https://openalex.org/W2086453455","https://openalex.org/W2091037239","https://openalex.org/W2096889017","https://openalex.org/W2100442076","https://openalex.org/W2102776378","https://openalex.org/W2115161162","https://openalex.org/W2116153402","https://openalex.org/W2123507114","https://openalex.org/W2144465160","https://openalex.org/W2164707302","https://openalex.org/W2170038823","https://openalex.org/W2236483120","https://openalex.org/W2325120303","https://openalex.org/W2395293327"],"related_works":["https://openalex.org/W1416979305","https://openalex.org/W2057553066","https://openalex.org/W2088700222","https://openalex.org/W2763531884","https://openalex.org/W2757632199","https://openalex.org/W1995273419","https://openalex.org/W2470732876","https://openalex.org/W2987153594","https://openalex.org/W2469172380","https://openalex.org/W2144465160"],"abstract_inverted_index":{"Compared":[0],"to":[1,67,79,95,120,195,242],"other":[2],"radiation":[3,197],"therapy":[4,9,49],"modalities,":[5],"clinical":[6],"electron":[7,21,41,48,75,102,245],"beam":[8,246],"has":[10,192],"remained":[11],"practically":[12],"unchanged":[13],"for":[14,163,178,267],"the":[15,37,92,101,109,116,141,193],"past":[16],"few":[17],"decades":[18],"even":[19],"though":[20],"beams":[22],"with":[23,51,91,140,199],"multiple":[24],"energies":[25,165],"are":[26],"widely":[27],"available":[28],"on":[29,124,131,247],"most":[30],"linacs.":[31],"In":[32,104,138],"this":[33,105],"paper,":[34],"we":[35,107],"present":[36],"concept":[38],"of":[39,58,111,118,208,257,270],"dynamic":[40],"arc":[42],"radiotherapy":[43,269],"(DEAR),":[44],"a":[45,179,243,248,264],"new":[46],"conformal":[47,268],"technique":[50,266],"synchronized":[52,90],"couch":[53,61,87,216],"motion.":[54],"DEAR":[55,112,119,128,187,252,263],"utilizes":[56],"combination":[57],"gantry":[59,93],"rotation,":[60],"motion,":[62],"and":[63,82,100,114,149,157,167,170,175,191,213,218,232],"dose":[64,70,122,150,159,198,220],"rate":[65,151,221],"modulation":[66,152],"achieve":[68],"desirable":[69],"distributions":[71,123,160],"in":[72,135,230],"patient.":[73],"The":[74,86],"applicator":[76],"is":[77,89,189],"kept":[78],"minimize":[80],"scatter":[81],"maintain":[83],"narrow":[84],"penumbra.":[85],"motion":[88,147],"rotation":[94],"avoid":[96],"collision":[97],"between":[98],"patient":[99],"cone.":[103],"study,":[106],"investigate":[108],"feasibility":[110],"delivery":[113,188],"demonstrate":[115],"potential":[117,194],"improve":[121],"simple":[125],"cylindrical":[126],"phantoms.":[127],"was":[129],"delivered":[130],"Varian's":[132],"TrueBeam":[133],"linac":[134],"Research":[136],"Mode.":[137],"conjunction":[139],"recorded":[142],"trajectory":[143],"log":[144],"files,":[145],"mechanical":[146],"accuracies":[148],"precision":[153,222],"were":[154,161],"analyzed.":[155],"Experimental":[156],"calculated":[158],"investigated":[162],"different":[164],"(6":[166],"9":[168],"MeV)":[169],"cut-out":[171],"sizes":[172],"(1\u00d710":[173],"cm(2)":[174,177,181],"3\u00d710":[176],"15\u00d715":[180],"applicator).":[182],"Our":[183],"findings":[184],"show":[185],"that":[186],"feasible":[190],"deliver":[196],"high":[200],"accuracy":[201],"(root":[202],"mean":[203],"square":[204],"error,":[205],"or":[206],"RMSE":[207],"<0.1":[209,214],"MU,":[210],"<0.1\u00b0":[211],"gantry,":[212],"cm":[215],"positions)":[217],"good":[219],"(1.6":[223],"MU":[224],"min(-1)).":[225],"Dose":[226],"homogeneity":[227],"within":[228],"\u00b12%":[229],"large":[231],"curved":[233],"targets":[234],"can":[235],"be":[236],"achieved":[237],"while":[238],"maintaining":[239],"penumbra":[240],"comparable":[241],"standard":[244],"flat":[249],"surface.":[250],"Further,":[251],"does":[253],"not":[254],"require":[255],"fabrication":[256],"patient-specific":[258],"shields.":[259],"These":[260],"benefits":[261],"make":[262],"promising":[265],"superficial":[271],"tumors.":[272]},"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}