{"id":"https://openalex.org/W1985693752","doi":"https://doi.org/10.1001/jama.1960.03030160038009","title":"Use of Silicone in the Treatment of Intestinal Gas and Bloating","display_name":"Use of Silicone in the Treatment of Intestinal Gas and Bloating","publication_year":1960,"publication_date":"1960-12-17","ids":{"openalex":"https://openalex.org/W1985693752","doi":"https://doi.org/10.1001/jama.1960.03030160038009","mag":"1985693752","pmid":"https://pubmed.ncbi.nlm.nih.gov/13741481"},"language":"en","primary_location":{"id":"doi:10.1001/jama.1960.03030160038009","doi":"https://doi.org/10.1001/jama.1960.03030160038009","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jama.1960.03030160038009","pdf_url":null,"source":{"id":"https://openalex.org/S172573765","display_name":"JAMA","issn_l":"0002-9955","issn":["0002-9955","0098-7484","1538-3598","2376-8118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111048052","display_name":"J. Alfred Rider","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"J. Alfred Rider","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5111048052"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9735,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.75152957,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"174","issue":"16","first_page":"2052","last_page":"2052"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10671","display_name":"Gastroesophageal reflux and treatments","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flatulence","display_name":"flatulence","score":0.8130000233650208},{"id":"https://openalex.org/keywords/bloating","display_name":"bloating","score":0.7710000276565552},{"id":"https://openalex.org/keywords/intestinal-gas","display_name":"intestinal gas","score":0.8640000224113464},{"id":"https://openalex.org/keywords/abdominal-distension","display_name":"abdominal distension","score":0.6679999828338623},{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.41100001335144043}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9460979700088501},{"id":"https://openalex.org/C2775913212","wikidata":"https://www.wikidata.org/wiki/Q160184","display_name":"Flatulence","level":2,"score":0.8985443115234375},{"id":"https://openalex.org/C2776956441","wikidata":"https://www.wikidata.org/wiki/Q4927059","display_name":"Bloating","level":3,"score":0.8123013377189636},{"id":"https://openalex.org/C2779769944","wikidata":"https://www.wikidata.org/wiki/Q146439","display_name":"Silicone","level":2,"score":0.7311453819274902},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.6443935632705688},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.46702244877815247},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.43985873460769653},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26614266633987427},{"id":"https://openalex.org/C2780580376","wikidata":"https://www.wikidata.org/wiki/Q186889","display_name":"Nausea","level":2,"score":0.20786768198013306},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07815244793891907},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D005762","descriptor_name":"Gastroenterology","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012828","descriptor_name":"Silicones","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1001/jama.1960.03030160038009","doi":"https://doi.org/10.1001/jama.1960.03030160038009","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jama.1960.03030160038009","pdf_url":null,"source":{"id":"https://openalex.org/S172573765","display_name":"JAMA","issn_l":"0002-9955","issn":["0002-9955","0098-7484","1538-3598","2376-8118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA","raw_type":"journal-article"},{"id":"pmid:13741481","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/13741481","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W1974412003","https://openalex.org/W1987239258","https://openalex.org/W2343128178","https://openalex.org/W2413343735"],"related_works":["https://openalex.org/W4242596805","https://openalex.org/W2408846035","https://openalex.org/W2402977561","https://openalex.org/W2399778628","https://openalex.org/W2398749186","https://openalex.org/W2410513273","https://openalex.org/W4366983387","https://openalex.org/W2074783335","https://openalex.org/W7099389944","https://openalex.org/W4392886166"],"abstract_inverted_index":{"Silicone":[0],"defoamers":[1],"have":[2],"been":[3],"used":[4],"successfully":[5],"to":[6,21,37,51],"eliminate":[7],"the":[8,17,97,100],"mucuscovered":[9],"bubbles":[10],"which":[11],"obstruct":[12],"a":[13,44,54,83,103],"gastroscopist's":[14],"view":[15],"of":[16,28,66,86,102],"stomach.":[18],"This":[19],"led":[20],"their":[22],"trial":[23],"in":[24,79,114],"treating":[25],"patients":[26,88],"complaining":[27],"flatulence":[29],"and":[30,53],"distention.":[31],"Two":[32],"hundred":[33],"patients,":[34],"aged":[35],"23":[36],"84":[38],"years,":[39],"were":[40],"given":[41],"methyl":[42,67,98],"polysiloxane,":[43,99],"physiologically":[45],"inert":[46],"silicone,":[47],"for":[48],"four":[49],"weeks":[50],"three":[52],"half":[55],"years.":[56],"Although":[57],"other":[58],"measures":[59],"had":[60,90,91],"not":[61],"relieved":[62],"symptoms,":[63],"40":[64],"mg.":[65],"polysiloxane":[68],"taken":[69],"orally":[70],"4":[71],"times":[72],"daily":[73],"produced":[74],"excellent":[75,92],"or":[76,93],"good":[77,94],"results":[78,95],"151":[80],"patients.":[81,116],"In":[82],"control":[84],"group":[85],"20":[87],"who":[89],"from":[96],"substitution":[101],"lactose":[104],"placebo":[105],"was":[106],"followed":[107],"by":[108],"renewed":[109],"complaints":[110],"within":[111],"24":[112],"hours":[113],"18":[115]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}