{"id":"https://openalex.org/W1985669372","doi":"https://doi.org/10.1080/10426500601087301","title":"Part 7: Synthesis of Some New 1,5-Benzodiazepines Fused with Different Heterocyclic Moieties","display_name":"Part 7: Synthesis of Some New 1,5-Benzodiazepines Fused with Different Heterocyclic Moieties","publication_year":2007,"publication_date":"2007-02-15","ids":{"openalex":"https://openalex.org/W1985669372","doi":"https://doi.org/10.1080/10426500601087301","mag":"1985669372"},"language":"en","primary_location":{"id":"doi:10.1080/10426500601087301","doi":"https://doi.org/10.1080/10426500601087301","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10426500601087301","pdf_url":null,"source":{"id":"https://openalex.org/S70121411","display_name":"Phosphorus, sulfur, and silicon and the related elements","issn_l":"1026-7719","issn":["1026-7719","1042-6507","1563-5325"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phosphorus, Sulfur, and Silicon and the Related Elements","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101435089","display_name":"Ahmed Mohamed Elsayed","orcid":"https://orcid.org/0000-0002-1227-4426","observed_orcids":["https://orcid.org/0000-0002-1227-4426","https://orcid.org/0000-0002-1692-5708"]},"institutions":[{"id":"https://openalex.org/I189575948","display_name":"South Valley University","ror":"https://ror.org/00jxshx33","country_code":"EG","type":"education","lineage":["https://openalex.org/I189575948"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"A. M. El-Sayed","raw_affiliation_strings":["a   Chemistry Department , South Valley University ,  Sohag ,  Egypt","Chemistry Department , South Valley University , Sohag , Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a   Chemistry Department , South Valley University ,  Sohag ,  Egypt","institution_ids":["https://openalex.org/I189575948"]},{"raw_affiliation_string":"Chemistry Department , South Valley University , Sohag , Egypt","institution_ids":["https://openalex.org/I189575948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020340156","display_name":"A. Khodairy","orcid":"https://orcid.org/0000-0002-7893-0385","observed_orcids":["https://orcid.org/0000-0002-7893-0385"]},"institutions":[{"id":"https://openalex.org/I189575948","display_name":"South Valley University","ror":"https://ror.org/00jxshx33","country_code":"EG","type":"education","lineage":["https://openalex.org/I189575948"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"A. Khodairy","raw_affiliation_strings":["a   Chemistry Department , South Valley University ,  Sohag ,  Egypt","Chemistry Department , South Valley University , Sohag , Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a   Chemistry Department , South Valley University ,  Sohag ,  Egypt","institution_ids":["https://openalex.org/I189575948"]},{"raw_affiliation_string":"Chemistry Department , South Valley University , Sohag , Egypt","institution_ids":["https://openalex.org/I189575948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102733390","display_name":"Hanan A. Salah","orcid":"https://orcid.org/0000-0003-3645-0874","observed_orcids":["https://orcid.org/0000-0003-3645-0874"]},"institutions":[{"id":"https://openalex.org/I189575948","display_name":"South Valley University","ror":"https://ror.org/00jxshx33","country_code":"EG","type":"education","lineage":["https://openalex.org/I189575948"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"H. Salah","raw_affiliation_strings":["a   Chemistry Department , South Valley University ,  Sohag ,  Egypt","Chemistry Department , South Valley University , Sohag , Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a   Chemistry Department , South Valley University ,  Sohag ,  Egypt","institution_ids":["https://openalex.org/I189575948"]},{"raw_affiliation_string":"Chemistry Department , South Valley University , Sohag , Egypt","institution_ids":["https://openalex.org/I189575948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112875397","display_name":"H. Abdel\u2010Ghany","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189575948","display_name":"South Valley University","ror":"https://ror.org/00jxshx33","country_code":"EG","type":"education","lineage":["https://openalex.org/I189575948"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"H. Abdel-Ghany","raw_affiliation_strings":["a   Chemistry Department , South Valley University ,  Sohag ,  Egypt","Chemistry Department , South Valley University , Sohag , Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a   Chemistry Department , South Valley University ,  Sohag ,  Egypt","institution_ids":["https://openalex.org/I189575948"]},{"raw_affiliation_string":"Chemistry Department , South Valley University , Sohag , Egypt","institution_ids":["https://openalex.org/I189575948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I189575948"],"apc_list":null,"apc_paid":null,"fwci":0.3409,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.532,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"182","issue":"4","first_page":"711","last_page":"722"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13105","display_name":"Synthesis and pharmacology of benzodiazepine derivatives","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13105","display_name":"Synthesis and pharmacology of benzodiazepine derivatives","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13208","display_name":"Synthesis of heterocyclic compounds","score":0.014399999752640724,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13876","display_name":"Chemical synthesis and pharmacological studies","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/1-5-benzodiazepines","display_name":"1,5-benzodiazepines","score":0.9919999837875366},{"id":"https://openalex.org/keywords/fused-heterocycles","display_name":"fused heterocycles","score":0.8799999952316284},{"id":"https://openalex.org/keywords/intramolecular-cyclization","display_name":"intramolecular cyclization","score":0.6629999876022339},{"id":"https://openalex.org/keywords/s-alkylation","display_name":"S-alkylation","score":0.7239999771118164},{"id":"https://openalex.org/keywords/phenyl-isothiocyanate","display_name":"phenyl isothiocyanate","score":0.843999981880188}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7819704413414001},{"id":"https://openalex.org/C2779854550","wikidata":"https://www.wikidata.org/wiki/Q407775","display_name":"Acetic anhydride","level":3,"score":0.6470726728439331},{"id":"https://openalex.org/C2780378348","wikidata":"https://www.wikidata.org/wiki/Q25351438","display_name":"Ring (chemistry)","level":2,"score":0.6314997673034668},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.5613164901733398},{"id":"https://openalex.org/C2779607818","wikidata":"https://www.wikidata.org/wiki/Q243354","display_name":"Carbon disulfide","level":2,"score":0.5591541528701782},{"id":"https://openalex.org/C2778173252","wikidata":"https://www.wikidata.org/wiki/Q83871","display_name":"Benzodiazepine","level":3,"score":0.55223149061203},{"id":"https://openalex.org/C164361826","wikidata":"https://www.wikidata.org/wiki/Q177604","display_name":"Alkylation","level":3,"score":0.5506809949874878},{"id":"https://openalex.org/C75079739","wikidata":"https://www.wikidata.org/wiki/Q1571801","display_name":"Intramolecular force","level":2,"score":0.49720457196235657},{"id":"https://openalex.org/C518881349","wikidata":"https://www.wikidata.org/wiki/Q682","display_name":"Sulfur","level":2,"score":0.4602891206741333},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.34416916966438293},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.22014394402503967},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.12831375002861023},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1080/10426500601087301","doi":"https://doi.org/10.1080/10426500601087301","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10426500601087301","pdf_url":null,"source":{"id":"https://openalex.org/S70121411","display_name":"Phosphorus, sulfur, and silicon and the related elements","issn_l":"1026-7719","issn":["1026-7719","1042-6507","1563-5325"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phosphorus, Sulfur, and Silicon and the Related Elements","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1860901295","https://openalex.org/W2010646930","https://openalex.org/W2015966867","https://openalex.org/W2024881763","https://openalex.org/W2068883123","https://openalex.org/W2109797349","https://openalex.org/W2145195979","https://openalex.org/W2177520640","https://openalex.org/W2475917507","https://openalex.org/W2950501711","https://openalex.org/W2950676609","https://openalex.org/W2951758541"],"related_works":["https://openalex.org/W2145195979","https://openalex.org/W4244405936","https://openalex.org/W2106360595","https://openalex.org/W2113023538","https://openalex.org/W2109797349","https://openalex.org/W2040407537","https://openalex.org/W2110125782","https://openalex.org/W2292041703","https://openalex.org/W2044991860","https://openalex.org/W2083509210"],"abstract_inverted_index":{"3-cyano-1,11-dihydro-4,5-diphenyl-2-thioxopyrido[2,3-b](1,5)benzodiazepine":[0],"2":[1,16,56],"and":[2,67,77,84,99,109],"3-(2\u2032-cyano-1\u2032-phenyl-2\u2032-ethanethiocarboxamide)-4-phenyl-1(H)(1,5)benzodiazepin2-one":[3],"3":[4],"were":[5,70],"prepared":[6],"via":[7,51],"the":[8,24,52,58],"reaction":[9,53,102],"of":[10,45,54,87,103],"1,3-dihydro-4-phenyl-(1,5)benzodiazepin-2-one":[11],"1":[12,66,105],"with":[13,19,57,72,90,106],"benzylidenecyanothioacetamide.":[14],"Compound":[15,65],"was":[17,49],"treated":[18,71],"halo":[20,60],"compounds":[21,27,46],"to":[22,36,80],"give":[23],"corresponding":[25],"S-alkylated":[26],"4":[28],"a\u2212c,":[29],"which":[30],"underwent":[31],"as":[32],"intramolecular":[33],"ring":[34],"closure":[35],"thieno[3,2.5,6]pyrido[2,3-b](1,5)benzodiazepines":[37],"5":[38,47],"a\u2212c":[39,48],"under":[40,62],"PTC":[41,63],"conditions.":[42,64],"One-pot":[43],"syntheis":[44],"achieved":[50],"compound":[55,61,88,104],"appropriate":[59],"1-ethyl-4-phenyl-(1,5)benzodiazepin-2-one":[68],"9":[69],"carbon":[73],"disulfide":[74],"or":[75,92],"phenylisothiocyanate":[76,91],"active":[78,110],"nitriles":[79,111],"afford":[81],"4-thioxothiopyrano[4,3-b](1,5)benzodiazepines":[82],"8":[83],"10\u201314.":[85],"Treatment":[86],"10":[89],"acetic":[93],"anhydride":[94],"yielded":[95,112],"oxazino-and":[96],"pyrimido[4,5-b]thiopyrano-[4\u2032,3\u2032-b\u2032](1,5)benzodiazepine":[97],"15":[98],"17.":[100],"The":[101],"elemental":[107],"sulfur":[108],"thieno[3,2-b](1,5)benzodiazepines":[113],"18\u201321,":[114],"respectively.":[115]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}