{"id":"https://openalex.org/W1985657707","doi":"https://doi.org/10.1161/01.res.71.1.3","title":"Exclusion of cardiac myosin heavy chain and actin gene involvement in hypertrophic cardiomyopathy of several French families.","display_name":"Exclusion of cardiac myosin heavy chain and actin gene involvement in hypertrophic cardiomyopathy of several French families.","publication_year":1992,"publication_date":"1992-07-01","ids":{"openalex":"https://openalex.org/W1985657707","doi":"https://doi.org/10.1161/01.res.71.1.3","mag":"1985657707","pmid":"https://pubmed.ncbi.nlm.nih.gov/1606666"},"language":"en","primary_location":{"id":"doi:10.1161/01.res.71.1.3","doi":"https://doi.org/10.1161/01.res.71.1.3","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.res.71.1.3","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.RES.71.1.3","source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.RES.71.1.3","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113764465","display_name":"Ketty Schwartz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"K Schwartz","raw_affiliation_strings":["Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036868448","display_name":"Jacques Samuel Beckmann","orcid":"https://orcid.org/0000-0002-9741-1900","observed_orcids":["https://orcid.org/0000-0002-9741-1900"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J Beckmann","raw_affiliation_strings":["Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004691865","display_name":"C\u00e9cile Dufour","orcid":"https://orcid.org/0000-0001-7708-0641","observed_orcids":["https://orcid.org/0000-0001-7708-0641"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C Dufour","raw_affiliation_strings":["Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095"]}]},{"author_position":"middle","author":{"id":null,"display_name":"L Faure","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"L Faure","raw_affiliation_strings":["Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109169511","display_name":"Fran\u00e7oise Fougerousse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F Fougerousse","raw_affiliation_strings":["Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043563400","display_name":"Lucie Carrier","orcid":"https://orcid.org/0000-0001-8776-5820","observed_orcids":["https://orcid.org/0000-0001-8776-5820"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"L Carrier","raw_affiliation_strings":["Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003272933","display_name":"Christian Hengstenberg","orcid":"https://orcid.org/0000-0002-8284-2994","observed_orcids":["https://orcid.org/0000-0002-8284-2994"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C Hengstenberg","raw_affiliation_strings":["Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095"]}]},{"author_position":"middle","author":{"id":null,"display_name":"D Cohen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"D Cohen","raw_affiliation_strings":["Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111425852","display_name":"Hans-Peter Vosberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"H P Vosberg","raw_affiliation_strings":["Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108584144","display_name":"A Sacrez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A Sacrez","raw_affiliation_strings":["Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 127, H\u00f4pital Lariboisi\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":10.2473,"has_fulltext":true,"cited_by_count":59,"citation_normalized_percentile":{"value":0.98556144,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"71","issue":"1","first_page":"3","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/familial-hypertrophic-cardiomyopathy","display_name":"familial hypertrophic cardiomyopathy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/linkage-analysis","display_name":"linkage analysis","score":0.7770000100135803},{"id":"https://openalex.org/keywords/chromosome-15q","display_name":"chromosome 15q","score":0.953000009059906},{"id":"https://openalex.org/keywords/microsatellite-markers","display_name":"microsatellite markers","score":0.7139999866485596},{"id":"https://openalex.org/keywords/genetic-heterogeneity","display_name":"genetic heterogeneity","score":0.5920000076293945},{"id":"https://openalex.org/keywords/exclusion-mapping","display_name":"exclusion mapping","score":0.5040000081062317},{"id":"https://openalex.org/keywords/autosomal-dominant-inheritance","display_name":"autosomal dominant inheritance","score":0.781000018119812},{"id":"https://openalex.org/keywords/sudden-cardiac-death","display_name":"sudden cardiac death","score":0.6809999942779541}],"concepts":[{"id":"https://openalex.org/C2780185194","wikidata":"https://www.wikidata.org/wiki/Q1364270","display_name":"Hypertrophic cardiomyopathy","level":2,"score":0.7453830242156982},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.6717313528060913},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6410726308822632},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6317493915557861},{"id":"https://openalex.org/C142870003","wikidata":"https://www.wikidata.org/wiki/Q843863","display_name":"Genetic linkage","level":3,"score":0.5799657106399536},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.48410284519195557},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.46200060844421387},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.45765718817710876},{"id":"https://openalex.org/C6997183","wikidata":"https://www.wikidata.org/wiki/Q271727","display_name":"Myosin","level":2,"score":0.4194333553314209},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13663527369499207},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.13422980904579163},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11326387524604797},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.09853896498680115},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005602","descriptor_name":"France","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008040","descriptor_name":"Genetic Linkage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009218","descriptor_name":"Myosins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009218","descriptor_name":"Myosins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010375","descriptor_name":"Pedigree","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015335","descriptor_name":"Molecular Probes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1161/01.res.71.1.3","doi":"https://doi.org/10.1161/01.res.71.1.3","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.res.71.1.3","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.RES.71.1.3","source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"},{"id":"pmid:1606666","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1606666","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation research","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unil.ch:iris/203653","doi":null,"is_oa":false,"landing_page_url":"https://iris.unil.ch/handle/iris/203653","pdf_url":null,"source":{"id":"https://openalex.org/S7407055444","display_name":"IRIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:oai:serval.unil.ch:BIB_B4DB7BF07223","doi":null,"is_oa":false,"landing_page_url":"https://serval.unil.ch/notice/serval:BIB_B4DB7BF07223","pdf_url":null,"source":{"id":"https://openalex.org/S4306401797","display_name":"SERVAL (Universit\u00e9 de Lausanne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210093590","host_organization_name":"Swiss School of Archaeology in Greece","host_organization_lineage":["https://openalex.org/I4210093590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Circulation Research, vol. 71, no. 1, pp. 3-8","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1161/01.res.71.1.3","doi":"https://doi.org/10.1161/01.res.71.1.3","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.res.71.1.3","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.RES.71.1.3","source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5600000023841858}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320320893","display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","ror":"https://ror.org/02vjkv261"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1985657707.pdf","grobid_xml":"https://content.openalex.org/works/W1985657707.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W2081632","https://openalex.org/W1542836032","https://openalex.org/W1604929717","https://openalex.org/W1608137383","https://openalex.org/W1987191674","https://openalex.org/W1999251970","https://openalex.org/W2004091176","https://openalex.org/W2021600728","https://openalex.org/W2032852179","https://openalex.org/W2122509013","https://openalex.org/W2342124050","https://openalex.org/W2471042242"],"related_works":["https://openalex.org/W2006377884","https://openalex.org/W2024321813","https://openalex.org/W1999652280","https://openalex.org/W2044735954","https://openalex.org/W2415113777","https://openalex.org/W2039090726","https://openalex.org/W1987191674","https://openalex.org/W7039477294","https://openalex.org/W1861605635","https://openalex.org/W1563098722"],"abstract_inverted_index":{"Familial":[0],"hypertrophic":[1],"cardiomyopathy":[2],"(FHC)":[3],"is":[4,20,31,41,112,132],"characterized":[5],"by":[6,118],"idiopathic":[7],"myocardial":[8],"hypertrophy,":[9],"which":[10],"often":[11],"and":[12,27,44,128,151],"predominantly":[13],"involves":[14],"the":[15,52,65,84,91,130,136,157,160,169,178,181],"interventricular":[16],"septum.":[17],"The":[18],"disease":[19,40,131],"transmitted":[21],"as":[22,165],"an":[23],"autosomal":[24],"dominant":[25],"trait,":[26],"its":[28],"major":[29],"risk":[30],"sudden":[32],"death.":[33],"It":[34],"was":[35],"recently":[36],"demonstrated":[37],"that":[38,45,109],"this":[39],"genetically":[42],"heterogeneous":[43],"in":[46,61,82,125,141,156],"13":[47],"of":[48,105,143,148,153,159,180],"18":[49],"unrelated":[50],"families":[51,101,117],"morbid":[53,170],"locus,":[54],"termed":[55],"FHC-1,":[56],"maps":[57],"to":[58,114,135],"chromosome":[59,97,149,154],"14q11-12":[60],"and/or":[62],"very":[63],"near":[64],"cardiac":[66,85,92],"beta-myosin":[67,86],"heavy":[68,87],"chain":[69,88],"gene.":[70],"We":[71,107],"have":[72],"performed":[73],"linkage":[74],"analysis":[75],"with":[76],"five":[77],"chromosomal":[78],"markers":[79,123,162],"detecting":[80],"polymorphisms":[81],"either":[83],"gene":[89,94],"or":[90],"actin":[93],"(located":[95],"on":[96,99],"15q)":[98],"eight":[100],"from":[102],"different":[103],"regions":[104],"France.":[106],"show":[108],"1)":[110],"it":[111],"possible":[113,166],"analyze":[115],"medium-sized":[116],"using":[119],"highly":[120],"informative":[121],"microsatellite":[122],"located":[124],"these":[126,144],"genes":[127,140,182],"2)":[129],"not":[133],"linked":[134],"two":[137],"contractile":[138],"protein":[139],"any":[142],"families.":[145],"Moreover,":[146],"10-20%":[147],"14":[150],"20-40%":[152],"15":[155],"vicinity":[158],"respective":[161],"were":[163],"excluded":[164],"locations":[167],"for":[168,184],"locus.":[171],"These":[172],"results":[173],"provide":[174],"new":[175],"insights":[176],"into":[177],"identification":[179],"responsible":[183],"FHC.":[185]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}