{"id":"https://openalex.org/W1985654855","doi":"https://doi.org/10.3109/13880209.2011.577436","title":"Anti-inflammatory, antioxidant and antifungal activity ofChuquiraga spinosa","display_name":"Anti-inflammatory, antioxidant and antifungal activity ofChuquiraga spinosa","publication_year":2011,"publication_date":"2011-05-09","ids":{"openalex":"https://openalex.org/W1985654855","doi":"https://doi.org/10.3109/13880209.2011.577436","mag":"1985654855","pmid":"https://pubmed.ncbi.nlm.nih.gov/21554005"},"language":"en","primary_location":{"id":"doi:10.3109/13880209.2011.577436","doi":"https://doi.org/10.3109/13880209.2011.577436","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13880209.2011.577436","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13880209.2011.577436?needAccess=true","source":{"id":"https://openalex.org/S130009153","display_name":"Pharmaceutical Biology","issn_l":"0925-1618","issn":["0925-1618","1388-0209","1744-5116"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutical Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.3109/13880209.2011.577436?needAccess=true","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Raquel Casado","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Raquel Casado","raw_affiliation_strings":["Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain. rcasado@alumni.unav.es","Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain. rcasado@alumni.unav.es","institution_ids":["https://openalex.org/I88155538"]},{"raw_affiliation_string":"Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058911434","display_name":"Amaya Landa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Amaya Landa","raw_affiliation_strings":["Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091359080","display_name":"Javier Calvo","orcid":"https://orcid.org/0000-0001-9513-0518","observed_orcids":["https://orcid.org/0000-0001-9513-0518"]},"institutions":[{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Javier Calvo","raw_affiliation_strings":["Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055463544","display_name":"Jos\u00e9 Mar\u00eda Garc\u00eda\u2010Mina","orcid":"https://orcid.org/0000-0001-6352-9612","observed_orcids":["https://orcid.org/0000-0001-6352-9612"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Mar\u00eda Garc\u00eda-Mina","raw_affiliation_strings":["R&D Department, Timac Agro Espa\u00f1a-Roullier Group, Pol\u00edgono Arazuri-Orcoyen, Orcoyen, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"R&D Department, Timac Agro Espa\u00f1a-Roullier Group, Pol\u00edgono Arazuri-Orcoyen, Orcoyen, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108488696","display_name":"Andrew Marston","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Andrew Marston","raw_affiliation_strings":["Laboratory of Pharmacognosy and Phytochemistry, School of Pharmacy Geneva-Lausanne, University of Geneva, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pharmacognosy and Phytochemistry, School of Pharmacy Geneva-Lausanne, University of Geneva, Geneva, Switzerland","institution_ids":["https://openalex.org/I114457229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056051113","display_name":"Kurt Hostettmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Kurt Hostettmann","raw_affiliation_strings":["Laboratory of Pharmacognosy and Phytochemistry, School of Pharmacy Geneva-Lausanne, University of Geneva, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pharmacognosy and Phytochemistry, School of Pharmacy Geneva-Lausanne, University of Geneva, Geneva, Switzerland","institution_ids":["https://openalex.org/I114457229"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101653676","display_name":"Mar\u00eda Isabel Calvo","orcid":"https://orcid.org/0000-0002-3159-0336","observed_orcids":["https://orcid.org/0000-0002-3159-0336"]},"institutions":[{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Mar\u00eda Isabel Calvo","raw_affiliation_strings":["Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I88155538"],"apc_list":{"value":2085,"currency":"GBP","value_usd":2557},"apc_paid":null,"fwci":1.1333,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.79139986,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"49","issue":"6","first_page":"620","last_page":"626"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.5717999935150146,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.5717999935150146,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.3005000054836273,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.10329999774694443,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asteraceae","display_name":"Asteraceae","score":0.8370000123977661},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.8379999995231628},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.9980000257492065},{"id":"https://openalex.org/keywords/antifungal-activity","display_name":"antifungal activity","score":1.0},{"id":"https://openalex.org/keywords/polyphenols","display_name":"polyphenols","score":0.75},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.9959999918937683},{"id":"https://openalex.org/keywords/phenolic-acids","display_name":"phenolic acids","score":0.9789999723434448},{"id":"https://openalex.org/keywords/carrageenan-induced-paw-edema","display_name":"carrageenan-induced paw edema","score":0.8700000047683716},{"id":"https://openalex.org/keywords/tpa-induced-ear-edema","display_name":"TPA-induced ear edema","score":0.9649999737739563},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.9350000023841858},{"id":"https://openalex.org/keywords/cladosporium-cucumerinum","display_name":"Cladosporium cucumerinum","score":0.9990000128746033},{"id":"https://openalex.org/keywords/plant-pathogenic-fungi","display_name":"plant pathogenic fungi","score":0.9279999732971191},{"id":"https://openalex.org/keywords/vaginitis","display_name":"vaginal infection","score":0.7670000195503235},{"id":"https://openalex.org/keywords/traditional-medicine","display_name":"traditional medicine","score":0.6620000004768372},{"id":"https://openalex.org/keywords/plant-extracts","display_name":"plant extracts","score":0.5009999871253967}],"concepts":[{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.7312248349189758},{"id":"https://openalex.org/C2781031786","wikidata":"https://www.wikidata.org/wiki/Q287582","display_name":"ABTS","level":4,"score":0.6421487331390381},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.5923704504966736},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.5823565125465393},{"id":"https://openalex.org/C70899900","wikidata":"https://www.wikidata.org/wiki/Q290439","display_name":"Polyphenol","level":3,"score":0.5733338594436646},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.5577419996261597},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5568550229072571},{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.54449462890625},{"id":"https://openalex.org/C2779703632","wikidata":"https://www.wikidata.org/wiki/Q581996","display_name":"Anti-inflammatory","level":2,"score":0.53282231092453},{"id":"https://openalex.org/C176947019","wikidata":"https://www.wikidata.org/wiki/Q597889","display_name":"Minimum inhibitory concentration","level":3,"score":0.4641464948654175},{"id":"https://openalex.org/C2781227287","wikidata":"https://www.wikidata.org/wiki/Q421991","display_name":"Carrageenan","level":2,"score":0.4551957845687866},{"id":"https://openalex.org/C2780751074","wikidata":"https://www.wikidata.org/wiki/Q7189797","display_name":"Phytomedicine","level":2,"score":0.41508129239082336},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2643902897834778},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.2586776614189148},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.25354862213134766},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2269708514213562},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.22183531522750854},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19734957814216614},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.07696306705474854}],"mesh":[{"descriptor_ui":"D000432","descriptor_name":"Methanol","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002351","descriptor_name":"Carrageenan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002963","descriptor_name":"Cladosporium","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004353","descriptor_name":"Drug Evaluation, Preclinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005419","descriptor_name":"Flavonoids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005419","descriptor_name":"Flavonoids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008517","descriptor_name":"Phytotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008519","descriptor_name":"Medicine, Traditional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010568","descriptor_name":"Peru","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013755","descriptor_name":"Tetradecanoylphorbol Acetate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019659","descriptor_name":"Asteraceae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D035261","descriptor_name":"Plant Components, Aerial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059808","descriptor_name":"Polyphenols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3109/13880209.2011.577436","doi":"https://doi.org/10.3109/13880209.2011.577436","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13880209.2011.577436","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13880209.2011.577436?needAccess=true","source":{"id":"https://openalex.org/S130009153","display_name":"Pharmaceutical Biology","issn_l":"0925-1618","issn":["0925-1618","1388-0209","1744-5116"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutical Biology","raw_type":"journal-article"},{"id":"pmid:21554005","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21554005","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutical biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3109/13880209.2011.577436","doi":"https://doi.org/10.3109/13880209.2011.577436","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13880209.2011.577436","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13880209.2011.577436?needAccess=true","source":{"id":"https://openalex.org/S130009153","display_name":"Pharmaceutical Biology","issn_l":"0925-1618","issn":["0925-1618","1388-0209","1744-5116"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutical Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1985654855.pdf","grobid_xml":"https://content.openalex.org/works/W1985654855.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W176585269","https://openalex.org/W332380621","https://openalex.org/W1537995961","https://openalex.org/W1883060321","https://openalex.org/W1981819970","https://openalex.org/W1997600674","https://openalex.org/W2000434713","https://openalex.org/W2012916551","https://openalex.org/W2015237826","https://openalex.org/W2026607868","https://openalex.org/W2040790475","https://openalex.org/W2043105940","https://openalex.org/W2047895809","https://openalex.org/W2050188943","https://openalex.org/W2069182775","https://openalex.org/W2071775811","https://openalex.org/W2078949221","https://openalex.org/W2081085034","https://openalex.org/W2086860395","https://openalex.org/W2089966048","https://openalex.org/W2092343007","https://openalex.org/W2092976065","https://openalex.org/W2095279035","https://openalex.org/W2146387229","https://openalex.org/W2164705448","https://openalex.org/W2254470205","https://openalex.org/W4256525953","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W3197035519","https://openalex.org/W3111881","https://openalex.org/W2616081685","https://openalex.org/W3217187995","https://openalex.org/W3080361926","https://openalex.org/W2329156815","https://openalex.org/W2754030830","https://openalex.org/W3122361912","https://openalex.org/W1692721100","https://openalex.org/W7035946002"],"abstract_inverted_index":{"CONTEXT:":[0],"Stem":[1],"and":[2,22,36,54,72,81,107,123,131,154,161,201,215,237,256,291,297,331],"leaves":[3],"infusion":[4],"of":[5,26,39,50,65,93,103,110,117,189,191,197,213,240,265,269,276,281,294,303,310,329,337],"Chuquiraga":[6],"spinosa":[7,41,60,312],"(R&P)":[8],"Don.":[9],"(Asteraceae)":[10],"is":[11],"used":[12],"in":[13,141,175,195,279],"the":[14,24,33,43,66,100,118,148,159,172,192,238,241,251,266,289,304,318,327,334],"Peruvian":[15],"traditional":[16],"medicine":[17],"for":[18,23,42,317],"its":[19],"anti-inflammatory":[20,35,277,292],"properties":[21,293],"treatment":[25],"vaginal":[27],"infections.":[28],"OBJECTIVE:":[29],"This":[30,181],"study":[31],"evaluated":[32,69,98],"antioxidant,":[34],"antifungal":[37,115,132,223,301],"activities":[38],"C.":[40,59,208,226,311],"first":[44,319],"time.":[45,320],"MATERIALS":[46],"AND":[47,232],"METHODS:":[48],"Extracts":[49],"methanol,":[51],"50%":[52,94,166,202,282],"methanol":[53,95,167,203,283],"water":[55],"were":[56,205],"obtained":[57,306],"from":[58,307],"aerial":[61,308],"parts.":[62],"Antioxidant":[63],"activity":[64,92,116,133,160,224,268,302],"extracts":[67,119,149,204,243,271,305],"was":[68,85,97,126,137,156,169,177],"(DPPH\u02d9,":[70],"ABTS\u02d9(+)":[71],"superoxide":[73],"radical-scavenging":[74,267],"activity).":[75],"The":[76,114,199,219,300],"correlation":[77,157],"between":[78,158],"these":[79,270],"results":[80],"total":[82,162],"polyphenolic":[83,163],"content":[84],"determined":[86],"by":[87,128,139,183,244],"Pearson's":[88],"Correlation":[89],"Coefficient.":[90],"Anti-inflammatory":[91],"extract":[96,168,221],"with":[99],"rat":[101],"model":[102,109],"carrageenan-induced":[104],"acute":[105,112],"inflammation":[106],"mouse":[108],"TPA-induced":[111,194],"inflammation.":[113],"against":[120,134,207,225],"Cladosporium":[121],"cucumerinum":[122,227],"Candida":[124],"albicans":[125,209],"studied":[127],"direct":[129],"bioautography,":[130],"phytopathogenic":[135],"fungi":[136],"performed":[138],"culture":[140],"potato":[142],"dextrose":[143],"agar":[144],"plates.":[145],"RESULTS:":[146],"All":[147],"showed":[150,222,250],"high":[151],"antioxidant":[152,290],"activity,":[153],"there":[155],"compounds.":[164],"As":[165],"administered":[170],"orally,":[171],"paw":[173],"edema":[174,193],"rats":[176],"reduced":[178],"significantly":[179],"(52.5%).":[180],"extract,":[182],"topical":[184],"administration,":[185],"produced":[186],"a":[187],"reduction":[188],"88.07%":[190],"ear":[196],"mice.":[198],"aqueous":[200,220],"active":[206],"(minimum":[210],"inhibitory":[211],"concentration":[212],"2.5":[214,229],"6.25":[216],"\u00b5g,":[217],"respectively).":[218],"(MIC:":[228],"\u00b5g).":[230],"DISCUSSION":[231],"CONCLUSION:":[233],"Preliminary":[234],"phytochemical":[235],"screening":[236],"analysis":[239],"three":[242],"high-performance":[245],"liquid":[246],"chromatography":[247],"diode-array":[248],"detection":[249],"majority":[252],"compounds":[253,261,336],"are":[254,323],"flavonoids":[255,296],"phenolic":[257,298],"acid":[258],"derivatives.":[259],"These":[260],"may":[262],"be":[263],"responsible":[264,275],"as":[272,274],"well":[273],"effect":[278],"vivo":[280],"extract.":[284],"Several":[285],"authors":[286],"have":[287],"demonstrated":[288],"some":[295],"acids.":[299],"parts":[309],"has":[313],"been":[314],"investigated":[315],"here":[316],"Other":[321],"studies":[322],"necessary":[324],"to":[325,332],"determine":[326],"mechanism":[328],"action":[330],"identify":[333],"bioactive":[335],"this":[338],"plant.":[339]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}