{"id":"https://openalex.org/W1985654472","doi":"https://doi.org/10.1523/jneurosci.5425-06.2007","title":"Sensory Deprivation Alters Aggrecan and Perineuronal Net Expression in the Mouse Barrel Cortex","display_name":"Sensory Deprivation Alters Aggrecan and Perineuronal Net Expression in the Mouse Barrel Cortex","publication_year":2007,"publication_date":"2007-05-16","ids":{"openalex":"https://openalex.org/W1985654472","doi":"https://doi.org/10.1523/jneurosci.5425-06.2007","mag":"1985654472","pmid":"https://pubmed.ncbi.nlm.nih.gov/17507562","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6672348"},"language":"en","primary_location":{"id":"doi:10.1523/jneurosci.5425-06.2007","doi":"https://doi.org/10.1523/jneurosci.5425-06.2007","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.5425-06.2007","pdf_url":"https://www.jneurosci.org/content/jneuro/27/20/5405.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jneurosci.org/content/jneuro/27/20/5405.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077722727","display_name":"Paulette A. McRae","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paulette A. McRae","raw_affiliation_strings":["Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077250479","display_name":"Mary M. Rocco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121847817","display_name":"The Graduate Center, CUNY","ror":"https://ror.org/00awd9g61","country_code":"US","type":"education","lineage":["https://openalex.org/I121847817"]},{"id":"https://openalex.org/I174216632","display_name":"City University of New York","ror":"https://ror.org/00453a208","country_code":"US","type":"education","lineage":["https://openalex.org/I174216632"]},{"id":"https://openalex.org/I20388574","display_name":"SUNY Upstate Medical University","ror":"https://ror.org/040kfrw16","country_code":"US","type":"education","lineage":["https://openalex.org/I20388574"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary M. Rocco","raw_affiliation_strings":["Department of Neuroscience and Physiology , WH 3238 , State University of New York Upstate Medical University , Syracuse , NY 13210 ","Neuropsychology PhD Subprogram, The Graduate Center, City University of New York (CUNY), New York, New York 10016,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience and Physiology , WH 3238 , State University of New York Upstate Medical University , Syracuse , NY 13210 ","institution_ids":["https://openalex.org/I20388574"]},{"raw_affiliation_string":"Neuropsychology PhD Subprogram, The Graduate Center, City University of New York (CUNY), New York, New York 10016,","institution_ids":["https://openalex.org/I121847817","https://openalex.org/I174216632"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103338581","display_name":"Gail M. Kelly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gail Kelly","raw_affiliation_strings":["Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520,","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058534161","display_name":"Joshua C. Brumberg","orcid":"https://orcid.org/0000-0002-9480-7547","observed_orcids":["https://orcid.org/0000-0002-9480-7547"]},"institutions":[{"id":"https://openalex.org/I111455621","display_name":"Queens College, CUNY","ror":"https://ror.org/03v8adn41","country_code":"US","type":"education","lineage":["https://openalex.org/I111455621"]},{"id":"https://openalex.org/I121847817","display_name":"The Graduate Center, CUNY","ror":"https://ror.org/00awd9g61","country_code":"US","type":"education","lineage":["https://openalex.org/I121847817"]},{"id":"https://openalex.org/I174216632","display_name":"City University of New York","ror":"https://ror.org/00453a208","country_code":"US","type":"education","lineage":["https://openalex.org/I174216632"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua C. Brumberg","raw_affiliation_strings":["Department of Psychology, Queens College, CUNY, Flushing, New York 11367, and","Neuropsychology PhD Subprogram, The Graduate Center, City University of New York (CUNY), New York, New York 10016,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, Queens College, CUNY, Flushing, New York 11367, and","institution_ids":["https://openalex.org/I111455621"]},{"raw_affiliation_string":"Neuropsychology PhD Subprogram, The Graduate Center, City University of New York (CUNY), New York, New York 10016,","institution_ids":["https://openalex.org/I121847817","https://openalex.org/I174216632"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003238248","display_name":"Russell T. Matthews","orcid":"https://orcid.org/0000-0002-9376-4215","observed_orcids":["https://orcid.org/0000-0002-9376-4215"]},"institutions":[{"id":"https://openalex.org/I20388574","display_name":"SUNY Upstate Medical University","ror":"https://ror.org/040kfrw16","country_code":"US","type":"education","lineage":["https://openalex.org/I20388574"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Russell T. Matthews","raw_affiliation_strings":["Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520,","Department of Neuroscience and Physiology, State University of New York Upstate Medical University, Syracuse, New York 13210"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520,","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Neuroscience and Physiology, State University of New York Upstate Medical University, Syracuse, New York 13210","institution_ids":["https://openalex.org/I20388574"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5003238248"],"corresponding_institution_ids":["https://openalex.org/I20388574","https://openalex.org/I32971472"],"apc_list":null,"apc_paid":null,"fwci":4.0954,"has_fulltext":true,"cited_by_count":279,"citation_normalized_percentile":{"value":0.95002676,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"27","issue":"20","first_page":"5405","last_page":"5413"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9375,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9375,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.02410000003874302,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/perineuronal-nets","display_name":"perineuronal nets","score":0.8970000147819519},{"id":"https://openalex.org/keywords/aggrecan","display_name":"aggrecan","score":0.996999979019165},{"id":"https://openalex.org/keywords/sensory-deprivation","display_name":"sensory deprivation","score":0.8659999966621399},{"id":"https://openalex.org/keywords/whisker-trimming","display_name":"whisker trimming","score":0.9369999766349792},{"id":"https://openalex.org/keywords/barrel-cortex","display_name":"barrel cortex","score":0.9900000095367432},{"id":"https://openalex.org/keywords/parvalbumin","display_name":"parvalbumin","score":0.7950000166893005},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.7990000247955322},{"id":"https://openalex.org/keywords/activity-dependent-synaptic-plasticity","display_name":"activity-dependent synaptic plasticity","score":0.7300000190734863},{"id":"https://openalex.org/keywords/critical-period","display_name":"critical period","score":0.972000002861023},{"id":"https://openalex.org/keywords/layer-4","display_name":"layer 4","score":0.6710000038146973},{"id":"https://openalex.org/keywords/proteoglycans","display_name":"proteoglycans","score":0.7590000033378601}],"concepts":[{"id":"https://openalex.org/C129987498","wikidata":"https://www.wikidata.org/wiki/Q7168586","display_name":"Perineuronal net","level":3,"score":0.9842496514320374},{"id":"https://openalex.org/C2781347215","wikidata":"https://www.wikidata.org/wiki/Q4863332","display_name":"Barrel cortex","level":3,"score":0.8851684331893921},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7364226579666138},{"id":"https://openalex.org/C141547260","wikidata":"https://www.wikidata.org/wiki/Q2720322","display_name":"Parvalbumin","level":2,"score":0.6907027363777161},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.635076105594635},{"id":"https://openalex.org/C197534660","wikidata":"https://www.wikidata.org/wiki/Q21121862","display_name":"Aggrecan","level":5,"score":0.6038994193077087},{"id":"https://openalex.org/C172497186","wikidata":"https://www.wikidata.org/wiki/Q328835","display_name":"Somatosensory system","level":2,"score":0.5603510737419128},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5018930435180664},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4646358788013458},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.0},{"id":"https://openalex.org/C3020332539","wikidata":"https://www.wikidata.org/wiki/Q2014564","display_name":"Articular cartilage","level":4,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012683","descriptor_name":"Sensory Deprivation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014738","descriptor_name":"Vibrissae","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D014738","descriptor_name":"Vibrissae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053674","descriptor_name":"Aggrecans","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D053674","descriptor_name":"Aggrecans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053674","descriptor_name":"Aggrecans","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1523/jneurosci.5425-06.2007","doi":"https://doi.org/10.1523/jneurosci.5425-06.2007","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.5425-06.2007","pdf_url":"https://www.jneurosci.org/content/jneuro/27/20/5405.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6672348","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6672348","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neurosci","raw_type":"Text"},{"id":"pmid:17507562","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17507562","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of neuroscience : the official journal of the Society for Neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.727.6819","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.727.6819","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://qcpages.qc.cuny.edu/Psychology/people/faculty/brumberg/Publications/McRaeetal2007.pdf","raw_type":"text"},{"id":"pmh:oai:academicworks.cuny.edu:qc_pubs-1387","doi":null,"is_oa":true,"landing_page_url":"https://academicworks.cuny.edu/qc_pubs/362","pdf_url":null,"source":{"id":"https://openalex.org/S4377196304","display_name":"CUNY Academic Works (City University of New York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I174216632","host_organization_name":"City University of New York","host_organization_lineage":["https://openalex.org/I174216632"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Publications and Research","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1523/jneurosci.5425-06.2007","doi":"https://doi.org/10.1523/jneurosci.5425-06.2007","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.5425-06.2007","pdf_url":"https://www.jneurosci.org/content/jneuro/27/20/5405.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1325532920","display_name":null,"funder_award_id":"NS 007224-21S1","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000897817","display_name":"Neurobiology of Cortical Systems","funder_award_id":"T32NS007224","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320309001","display_name":"American Psychological Association","ror":"https://ror.org/00rt1d436"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1985654472.pdf","grobid_xml":"https://content.openalex.org/works/W1985654472.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W48695541","https://openalex.org/W235963444","https://openalex.org/W1484033711","https://openalex.org/W1488311471","https://openalex.org/W1565093490","https://openalex.org/W1839558765","https://openalex.org/W1870538900","https://openalex.org/W1883330555","https://openalex.org/W1923448222","https://openalex.org/W1963685656","https://openalex.org/W1966167828","https://openalex.org/W1968455009","https://openalex.org/W1974815300","https://openalex.org/W1983683998","https://openalex.org/W1986126224","https://openalex.org/W1989245052","https://openalex.org/W1993916224","https://openalex.org/W1993936506","https://openalex.org/W1995089204","https://openalex.org/W2012993742","https://openalex.org/W2023003530","https://openalex.org/W2026158445","https://openalex.org/W2027419157","https://openalex.org/W2032124585","https://openalex.org/W2034204817","https://openalex.org/W2035496764","https://openalex.org/W2045100245","https://openalex.org/W2055559689","https://openalex.org/W2062813684","https://openalex.org/W2065585647","https://openalex.org/W2071526203","https://openalex.org/W2077729437","https://openalex.org/W2077969408","https://openalex.org/W2081655757","https://openalex.org/W2085209794","https://openalex.org/W2088475496","https://openalex.org/W2091187766","https://openalex.org/W2093539222","https://openalex.org/W2099040370","https://openalex.org/W2108841190","https://openalex.org/W2111405228","https://openalex.org/W2117910613","https://openalex.org/W2120149411","https://openalex.org/W2120301129","https://openalex.org/W2129972752","https://openalex.org/W2153572755","https://openalex.org/W2157282099","https://openalex.org/W2157352643","https://openalex.org/W2159967267","https://openalex.org/W2325060126"],"related_works":["https://openalex.org/W7099403346","https://openalex.org/W4410860404","https://openalex.org/W2612023626","https://openalex.org/W2894865807","https://openalex.org/W7171621658","https://openalex.org/W2067716913","https://openalex.org/W2046833863","https://openalex.org/W2065527300","https://openalex.org/W2414377682","https://openalex.org/W3166229206"],"abstract_inverted_index":{"An":[0],"important":[1,98,215],"role":[2,216,231],"for":[3,217,232],"the":[4,26,31,46,56,69,72,83,86,122,131,171,178,192,220,239,242],"neural":[5,32],"extracellular":[6,51],"matrix":[7,33,52],"in":[8,100,121,130,137,167,174,211,219,237],"modulating":[9],"cortical":[10],"activity-dependent":[11,139,221],"synaptic":[12],"plasticity":[13],"has":[14,90,108],"been":[15,91],"established":[16],"by":[17,141],"a":[18,63,155,164,185,230],"number":[19],"of":[20,25,30,62,65,68,71,78,85,113,158,177,189,213,223,234,241],"recent":[21],"studies.":[22],"However,":[23],"identification":[24],"critical":[27,87,243],"molecular":[28],"components":[29],"that":[34,93,111,198],"mediate":[35],"these":[36,199,208,235],"processes":[37],"is":[38,45,115,191],"far":[39],"from":[40],"complete.":[41],"Of":[42],"particular":[43],"interest":[44],"perineuronal":[47],"net":[48],"(PN),":[49],"an":[50,138,214],"component":[53,188],"found":[54],"surrounding":[55],"cell":[57],"body":[58],"and":[59,76,103,228],"proximal":[60],"neurites":[61],"subset":[64],"neurons.":[66],"Because":[67],"apposition":[70],"PN":[73],"to":[74,154,163],"synapses":[75],"expression":[77,112,233],"this":[79,149],"structure":[80],"coincident":[81],"with":[82,170],"close":[84,240],"period,":[88],"it":[89],"hypothesized":[92],"nets":[94,236],"could":[95],"play":[96],"uniquely":[97],"roles":[99],"synapse":[101],"stabilization":[102],"maturation.":[104],"Interestingly,":[105],"previous":[106],"work":[107],"also":[109,196,204],"shown":[110],"PNs":[114,129,159,190,224],"dependent":[116],"on":[117,225],"appropriate":[118],"sensory":[119,143],"stimulation":[120],"visual":[123],"system.":[124],"Here,":[125],"we":[126,183],"investigated":[127],"whether":[128],"mouse":[132],"barrel":[133,179],"cortex":[134],"are":[135,210],"expressed":[136],"manner":[140],"manipulating":[142],"input":[144],"through":[145],"whisker":[146],"trimming.":[147],"Importantly,":[148],"manipulation":[150],"did":[151],"not":[152],"lead":[153],"global":[156],"loss":[157],"but":[160],"instead":[161],"led":[162],"specific":[165],"decrease":[166],"PNs,":[168],"detected":[169],"antibody":[172],"Cat-315,":[173],"layer":[175],"IV":[176],"cortex.":[180],"In":[181],"addition,":[182],"identified":[184],"key":[186],"activity-regulated":[187],"proteoglycan":[193],"aggrecan.":[194],"We":[195],"demonstrate":[197],"Cat-315-positive":[200],"neurons":[201],"virtually":[202],"all":[203],"express":[205],"parvalbumin.":[206],"Together,":[207],"data":[209],"support":[212],"aggrecan":[218],"formation":[222],"parvalbumin-expressing":[226],"cells":[227],"suggest":[229],"regulating":[238],"period.":[244]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":17},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":18},{"year":2018,"cited_by_count":19},{"year":2017,"cited_by_count":22},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":20},{"year":2014,"cited_by_count":24},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":14}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}