{"id":"https://openalex.org/W1985512640","doi":"https://doi.org/10.1016/s0959-440x(02)00384-6","title":"Predicted and experimental structures of integrins and \u03b2-propellers","display_name":"Predicted and experimental structures of integrins and \u03b2-propellers","publication_year":2002,"publication_date":"2002-12-01","ids":{"openalex":"https://openalex.org/W1985512640","doi":"https://doi.org/10.1016/s0959-440x(02)00384-6","mag":"1985512640","pmid":"https://pubmed.ncbi.nlm.nih.gov/12504686"},"language":"en","primary_location":{"id":"doi:10.1016/s0959-440x(02)00384-6","doi":"https://doi.org/10.1016/s0959-440x(02)00384-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0959-440x(02)00384-6","pdf_url":null,"source":{"id":"https://openalex.org/S175155502","display_name":"Current Opinion in Structural Biology","issn_l":"0959-440X","issn":["0959-440X","1879-033X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Structural Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003615852","display_name":"Timothy A. Springer","orcid":"https://orcid.org/0000-0001-6627-2904","observed_orcids":["https://orcid.org/0000-0001-6627-2904"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"T Springer","raw_affiliation_strings":["Center for Blood Research and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA. springeroffice@cbr.med.harvard.edu","Center for Blood Research and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Blood Research and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA. springeroffice@cbr.med.harvard.edu","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Center for Blood Research and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5003615852"],"corresponding_institution_ids":["https://openalex.org/I136199984"],"apc_list":{"value":4360,"currency":"USD","value_usd":4360},"apc_paid":null,"fwci":2.7052,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.88682277,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"12","issue":"6","first_page":"802","last_page":"813"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.07289999723434448,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.010400000028312206,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/integrins","display_name":"integrins","score":0.9959999918937683},{"id":"https://openalex.org/keywords/beta-propeller-domain","display_name":"beta-propeller domain","score":0.7889999747276306},{"id":"https://openalex.org/keywords/protein-structure-prediction","display_name":"protein structure prediction","score":0.7950000166893005},{"id":"https://openalex.org/keywords/ligand-binding","display_name":"ligand binding","score":0.7940000295639038},{"id":"https://openalex.org/keywords/conformational-control","display_name":"conformational control","score":0.9900000095367432},{"id":"https://openalex.org/keywords/cell-surface-receptors","display_name":"cell surface receptors","score":0.875},{"id":"https://openalex.org/keywords/integrin-structure","display_name":"integrin structure","score":0.6309999823570251}],"concepts":[{"id":"https://openalex.org/C195687474","wikidata":"https://www.wikidata.org/wiki/Q409715","display_name":"Integrin","level":3,"score":0.8648451566696167},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5759395360946655},{"id":"https://openalex.org/C80055088","wikidata":"https://www.wikidata.org/wiki/Q205451","display_name":"Propeller","level":2,"score":0.4665864109992981},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.44263556599617004},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39577874541282654},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38491058349609375},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.363027423620224},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35826271772384644},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19453033804893494},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1695365011692047},{"id":"https://openalex.org/C199104240","wikidata":"https://www.wikidata.org/wiki/Q118291","display_name":"Marine engineering","level":1,"score":0.056506335735321045}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014841","descriptor_name":"von Willebrand Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014841","descriptor_name":"von Willebrand Factor","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016023","descriptor_name":"Integrins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016023","descriptor_name":"Integrins","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D016023","descriptor_name":"Integrins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021122","descriptor_name":"Protein Subunits","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D021122","descriptor_name":"Protein Subunits","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0959-440x(02)00384-6","doi":"https://doi.org/10.1016/s0959-440x(02)00384-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0959-440x(02)00384-6","pdf_url":null,"source":{"id":"https://openalex.org/S175155502","display_name":"Current Opinion in Structural Biology","issn_l":"0959-440X","issn":["0959-440X","1879-033X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Structural Biology","raw_type":"journal-article"},{"id":"pmid:12504686","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12504686","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in structural biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G180936245","display_name":null,"funder_award_id":"CA 31799","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6032462363","display_name":"INTEGRINS AND MODULAR SURFACE PROTEINS IN VASCULATURE","funder_award_id":"P01HL048675","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320338286","display_name":"Lawrence Livermore National Laboratory","ror":"https://ror.org/041nk4h53"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W84740065","https://openalex.org/W294119696","https://openalex.org/W1487053853","https://openalex.org/W1489612807","https://openalex.org/W1490451576","https://openalex.org/W1499450468","https://openalex.org/W1505634985","https://openalex.org/W1550140963","https://openalex.org/W1555059577","https://openalex.org/W1576773659","https://openalex.org/W1646222158","https://openalex.org/W1865931858","https://openalex.org/W1938388466","https://openalex.org/W1955186839","https://openalex.org/W1972470306","https://openalex.org/W1977922844","https://openalex.org/W1983052493","https://openalex.org/W1988827160","https://openalex.org/W1994065774","https://openalex.org/W1995782088","https://openalex.org/W1996257032","https://openalex.org/W1998072224","https://openalex.org/W2001803423","https://openalex.org/W2002590458","https://openalex.org/W2006481713","https://openalex.org/W2024022616","https://openalex.org/W2028575077","https://openalex.org/W2030390780","https://openalex.org/W2031122845","https://openalex.org/W2044831835","https://openalex.org/W2046757163","https://openalex.org/W2057979638","https://openalex.org/W2058685131","https://openalex.org/W2063559096","https://openalex.org/W2066371830","https://openalex.org/W2074492469","https://openalex.org/W2074619197","https://openalex.org/W2079357894","https://openalex.org/W2082439907","https://openalex.org/W2088730755","https://openalex.org/W2089860497","https://openalex.org/W2094469836","https://openalex.org/W2095272173","https://openalex.org/W2098438673","https://openalex.org/W2112715538","https://openalex.org/W2125717174","https://openalex.org/W2127883250","https://openalex.org/W2130285647","https://openalex.org/W2132717858","https://openalex.org/W2133169381","https://openalex.org/W2150670309","https://openalex.org/W2159874398","https://openalex.org/W2170877356","https://openalex.org/W2171335714","https://openalex.org/W2237362476","https://openalex.org/W3139752542"],"related_works":["https://openalex.org/W2074619197","https://openalex.org/W2079357894","https://openalex.org/W1550140963","https://openalex.org/W1975118393","https://openalex.org/W2574249624","https://openalex.org/W2005480360","https://openalex.org/W2147718912","https://openalex.org/W73966685","https://openalex.org/W3003854772","https://openalex.org/W2167743648"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
