{"id":"https://openalex.org/W1985504657","doi":"https://doi.org/10.1021/np020145e","title":"Cytotoxic Pyrrolo- and Furanoterpenoids from the Sponge Sarcotragus Species","display_name":"Cytotoxic Pyrrolo- and Furanoterpenoids from the Sponge Sarcotragus Species","publication_year":2002,"publication_date":"2002-08-20","ids":{"openalex":"https://openalex.org/W1985504657","doi":"https://doi.org/10.1021/np020145e","mag":"1985504657","pmid":"https://pubmed.ncbi.nlm.nih.gov/12350153"},"language":"en","primary_location":{"id":"doi:10.1021/np020145e","doi":"https://doi.org/10.1021/np020145e","is_oa":false,"landing_page_url":"https://doi.org/10.1021/np020145e","pdf_url":null,"source":{"id":"https://openalex.org/S166799026","display_name":"Journal of Natural Products","issn_l":"0163-3864","issn":["0163-3864","1520-6025"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Natural Products","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100620728","display_name":"Yonghong Liu","orcid":"https://orcid.org/0000-0001-8327-3108","observed_orcids":["https://orcid.org/0000-0001-8327-3108","https://orcid.org/0009-0003-7509-2157","https://orcid.org/0000-0002-4964-4996"]},"institutions":[{"id":"https://openalex.org/I4210139925","display_name":"Korea Basic Science Institute","ror":"https://ror.org/0417sdw47","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210139925","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]},{"id":"https://openalex.org/I4210151417","display_name":"Korea Research Institute of Chemical Technology","ror":"https://ror.org/043k4kk20","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210151417"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]},{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yonghong Liu","raw_affiliation_strings":["College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea","institution_ids":["https://openalex.org/I4210139925","https://openalex.org/I4210151417","https://openalex.org/I4921948","https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112325926","display_name":"Jongki Hong","orcid":"https://orcid.org/0000-0003-0456-3014","observed_orcids":["https://orcid.org/0000-0003-0456-3014","https://orcid.org/0000-0001-7742-5232"]},"institutions":[{"id":"https://openalex.org/I4210139925","display_name":"Korea Basic Science Institute","ror":"https://ror.org/0417sdw47","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210139925","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]},{"id":"https://openalex.org/I4210151417","display_name":"Korea Research Institute of Chemical Technology","ror":"https://ror.org/043k4kk20","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210151417"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]},{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jongki Hong","raw_affiliation_strings":["College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea","institution_ids":["https://openalex.org/I4210139925","https://openalex.org/I4210151417","https://openalex.org/I4921948","https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007751763","display_name":"Chong\u2010O. Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139925","display_name":"Korea Basic Science Institute","ror":"https://ror.org/0417sdw47","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210139925","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]},{"id":"https://openalex.org/I4210151417","display_name":"Korea Research Institute of Chemical Technology","ror":"https://ror.org/043k4kk20","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210151417"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]},{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chong-O. Lee","raw_affiliation_strings":["College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea","institution_ids":["https://openalex.org/I4210139925","https://openalex.org/I4210151417","https://openalex.org/I4921948","https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110053800","display_name":"Kwang Sik Im","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139925","display_name":"Korea Basic Science Institute","ror":"https://ror.org/0417sdw47","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210139925","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]},{"id":"https://openalex.org/I4210151417","display_name":"Korea Research Institute of Chemical Technology","ror":"https://ror.org/043k4kk20","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210151417"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]},{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kwang Sik Im","raw_affiliation_strings":["College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea","institution_ids":["https://openalex.org/I4210139925","https://openalex.org/I4210151417","https://openalex.org/I4921948","https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058337989","display_name":"Nam Deuk Kim","orcid":"https://orcid.org/0000-0001-9033-9865","observed_orcids":["https://orcid.org/0000-0001-9033-9865"]},"institutions":[{"id":"https://openalex.org/I4210139925","display_name":"Korea Basic Science Institute","ror":"https://ror.org/0417sdw47","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210139925","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]},{"id":"https://openalex.org/I4210151417","display_name":"Korea Research Institute of Chemical Technology","ror":"https://ror.org/043k4kk20","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210151417"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]},{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Nam Deuk Kim","raw_affiliation_strings":["College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea","institution_ids":["https://openalex.org/I4210139925","https://openalex.org/I4210151417","https://openalex.org/I4921948","https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101670664","display_name":"Jae Sue Choi","orcid":"https://orcid.org/0000-0001-9034-8868","observed_orcids":["https://orcid.org/0000-0001-9034-8868"]},"institutions":[{"id":"https://openalex.org/I4210139925","display_name":"Korea Basic Science Institute","ror":"https://ror.org/0417sdw47","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210139925","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]},{"id":"https://openalex.org/I4210151417","display_name":"Korea Research Institute of Chemical Technology","ror":"https://ror.org/043k4kk20","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210151417"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]},{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jae Sue Choi","raw_affiliation_strings":["College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea","institution_ids":["https://openalex.org/I4210139925","https://openalex.org/I4210151417","https://openalex.org/I4921948","https://openalex.org/I8991828"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035224329","display_name":"Jee Hyung Jung","orcid":"https://orcid.org/0000-0002-6299-0383","observed_orcids":["https://orcid.org/0000-0002-6299-0383"]},"institutions":[{"id":"https://openalex.org/I4210139925","display_name":"Korea Basic Science Institute","ror":"https://ror.org/0417sdw47","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210139925","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]},{"id":"https://openalex.org/I4210151417","display_name":"Korea Research Institute of Chemical Technology","ror":"https://ror.org/043k4kk20","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210151417"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]},{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jee H. Jung","raw_affiliation_strings":["College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Pusan National University, Pusan 609-735, Korea, Hazardous Substance Research Team, Korea Basic Science Institute, Seoul, Korea, Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology, Taejon, Korea, and Faculty of Food Science and Biotechnology, Pukyung National University, Pusan, Korea","institution_ids":["https://openalex.org/I4210139925","https://openalex.org/I4210151417","https://openalex.org/I4921948","https://openalex.org/I8991828"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":2.7356,"has_fulltext":false,"cited_by_count":58,"citation_normalized_percentile":{"value":0.87272727,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"65","issue":"9","first_page":"1307","last_page":"1314"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11340","display_name":"Marine Sponges and Natural Products","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11340","display_name":"Marine Sponges and Natural Products","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13971","display_name":"Isoquinoline Alkaloid Synthesis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/marine-sponge-natural-products","display_name":"marine sponge natural products","score":0.8130000233650208},{"id":"https://openalex.org/keywords/diterpenes","display_name":"diterpenoids","score":0.9660000205039978},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.753000020980835},{"id":"https://openalex.org/keywords/human-cancer-cell-lines","display_name":"human cancer cell lines","score":0.8560000061988831},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.5659999847412109}],"concepts":[{"id":"https://openalex.org/C2778849931","wikidata":"https://www.wikidata.org/wiki/Q18960","display_name":"Sponge","level":2,"score":0.9115482568740845},{"id":"https://openalex.org/C2776568683","wikidata":"https://www.wikidata.org/wiki/Q23005640","display_name":"Moiety","level":2,"score":0.8075350522994995},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.7953047752380371},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.6336703896522522},{"id":"https://openalex.org/C66974803","wikidata":"https://www.wikidata.org/wiki/Q10359898","display_name":"Nuclear magnetic resonance spectroscopy","level":2,"score":0.5426119565963745},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5048266053199768},{"id":"https://openalex.org/C19549132","wikidata":"https://www.wikidata.org/wiki/Q11141463","display_name":"Two-dimensional nuclear magnetic resonance spectroscopy","level":2,"score":0.5004673004150391},{"id":"https://openalex.org/C160492267","wikidata":"https://www.wikidata.org/wiki/Q319616","display_name":"Pharmacognosy","level":4,"score":0.4899224638938904},{"id":"https://openalex.org/C97428945","wikidata":"https://www.wikidata.org/wiki/Q15305109","display_name":"Fractionation","level":2,"score":0.4566383361816406},{"id":"https://openalex.org/C116073593","wikidata":"https://www.wikidata.org/wiki/Q864491","display_name":"Biological activity","level":3,"score":0.338143527507782},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.242156982421875},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.19243159890174866},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18641236424446106},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.1653393805027008},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.1568184494972229}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004354","descriptor_name":"Drug Screening Assays, Antitumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005663","descriptor_name":"Furans","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D005663","descriptor_name":"Furans","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005663","descriptor_name":"Furans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010679","descriptor_name":"Philippines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011161","descriptor_name":"Porifera","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013237","descriptor_name":"Stereoisomerism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016543","descriptor_name":"Central Nervous System Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019906","descriptor_name":"Nuclear Magnetic Resonance, Biomolecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/np020145e","doi":"https://doi.org/10.1021/np020145e","is_oa":false,"landing_page_url":"https://doi.org/10.1021/np020145e","pdf_url":null,"source":{"id":"https://openalex.org/S166799026","display_name":"Journal of Natural Products","issn_l":"0163-3864","issn":["0163-3864","1520-6025"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Natural Products","raw_type":"journal-article"},{"id":"pmid:12350153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12350153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of natural products","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1563124950","https://openalex.org/W2026515463","https://openalex.org/W2050304407","https://openalex.org/W2065213774","https://openalex.org/W2081401414","https://openalex.org/W2109630875","https://openalex.org/W2951510597","https://openalex.org/W2952181549"],"related_works":["https://openalex.org/W2017676705","https://openalex.org/W2045360949","https://openalex.org/W2036825209","https://openalex.org/W2950548313","https://openalex.org/W4319063077","https://openalex.org/W2092020513","https://openalex.org/W2051660130","https://openalex.org/W2138934549","https://openalex.org/W2082078525","https://openalex.org/W2310155704"],"abstract_inverted_index":{"Reexamination":[0],"of":[1,4,20,71,83],"the":[2,10,17,21,57,69],"configuration":[3],"sarcotins":[5],"A-C,":[6],"first":[7],"isolated":[8,55],"from":[9,56],"marine":[11],"sponge":[12,59],"Sarcotragus":[13],"sp.,":[14],"revealed":[15],"that":[16],"proposed":[18],"stereochemistry":[19,77],"tetronic":[22],"acid":[23],"moiety":[24],"needs":[25],"to":[26,105,108],"be":[27],"revised":[28],"as":[29],"shown":[30],"in":[31],"1-3.":[32],"Additional":[33],"new":[34],"pyrrolosesterterpenes":[35],"(5-11),":[36],"furanosesterpene":[37],"derivatives":[38],"(4,":[39],"12-14,":[40],"19),":[41],"and":[42,49,73,87,102],"furanoterpenoids,":[43],"including":[44],"two":[45,50],"trinorsesterterpenes":[46],"(15,":[47],"16)":[48],"diterpenes":[51],"(17,":[52],"18),":[53],"were":[54,66,92,103],"same":[58],"by":[60,80],"bioactivity-guided":[61],"fractionation.":[62],"The":[63,76,90],"planar":[64],"structures":[65],"established":[67],"on":[68],"basis":[70],"NMR":[72],"MS":[74],"analysis.":[75],"was":[78],"defined":[79],"combined":[81],"use":[82],"NMR,":[84],"CD":[85],"spectroscopy,":[86],"chemical":[88],"degradation.":[89],"compounds":[91],"evaluated":[93],"for":[94],"cytotoxicity":[95],"against":[96],"five":[97],"human":[98],"tumor":[99],"cell":[100],"lines":[101],"found":[104],"exhibit":[106],"moderate":[107],"significant":[109],"activity.":[110]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":6},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}